A Mouse Model with Ablated Asparaginase and Isoaspartyl Peptidase 1 (<i>Asrgl1</i>) Develops Early Onset Retinal Degeneration (RD) Recapitulating the Human Phenotype by Pooja Biswas, Anne Marie Berry, Qais Zawaydeh, Dirk-Uwe G. Bartsch, Pongali B. Raghavendra, J. Fielding Hejtmancik, Naheed W. Khan, S. Amer Riazuddin, Radha Ayyagari

Get full text

Positioning In Macular hole Surgery (PIMS): statistical analysis plan for a randomised controlled trial by Lauren Bell, Richard Hooper, Catey Bunce, Saruban Pasu, James Bainbridge

“…Secondary outcome measures at 3 months are: further surgery for macular holes performed or planned (of those with unsuccessful closure); patient-reported experience of positioning; whether patients report they would still have elected to have the operation given what they know at follow-up; best-corrected visual acuity (BCVA) measured using Snellen charts at a standard distance of 6 m; patient-reported health and quality of life assessed using the National Eye Institute Visual Function Questionnaire (VFQ-25). …”
Get full text

Efficacy of MP-3 microperimeter biofeedback fixation training for low vision rehabilitation in patients with maculopathy by Tianwei Qian, Xian Xu, Xinyi Liu, Manni Yen, Hao Zhou, Manman Mao, Huiting Cai, Hangqi Shen, Xun Xu, Yuanyuan Gong, Suqin Yu

“…Best corrected visual acuity (BCVA), reading speed, mean central sensitivity, the percentages of fixation points within specified regions, bivariate contour ellipse area (BCEA) and the 25-item National Eye Institute visual function questionnaire (NEI-VFQ-25) were recorded pre- and post-training. …”
Get full text

Clinical Documentation during Scribed and Nonscribed Ophthalmology Office Visits by Haley L. Dusek, MD, Isaac H. Goldstein, BA, Adam Rule, PhD, Michael F. Chiang, MD, Michelle R. Hribar, PhD

Get full text

Chronic central serous chorioretinopathy: long-term follow-up and vision-related quality of life by Breukink MB, Dingemans AJM, den Hollander AI, Keunen JEE, MacLaren RE, Fauser S, Querques G, Hoyng CB, Downes SM, Boon CJF

“…Extensive ophthalmic examination and a validated questionnaire concerning vision-related quality of life (National Eye Institute Visual Function Questionnaire [NEI-VFQ]-39) were analyzed.Results: Mean visual acuity showed a significant decline over time of 0.16 logarithm of minimum angle of resolution ([logMAR] range: -0.22 to 1.3;&nbsp;P=0.009) after a mean follow-up period of 10.6 years. …”
Get full text

Randomised, Single Blind, Controlled, Three-Month Clinical Trial on the Evaluation and Treatment of the Ocular Surface Damage Following Phacoemulsification by Gemma Caterina Maria Rossi, Carmine Tinelli, Giovanni Milano, Sara Lanteri, Gabriella Ricciarelli, Laura Giannì, Gian Maria Pasinetti, Luigia Scudeller

“…Design and Methods: Patients in the operative list for phacoemulsification have been screened for eligibility; they underwent (at time 0, 15, 45 and 90 days): slit lamp examination; tear film break-up time (BUT); corneal staining; tear volume; 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ); Ocular Surface Disease Index (OSDI). …”
Get full text

Efficacy of Qiju Dihuang decoction combined with sodium hyaluronate eye drops in the treatment of xerophthalmia after cataract surgery by Min Zhao, Xia Tian, Xi-Li Xiao, Xiao-Yan Wu

“…The clinical efficacy, Traditional Chinese Medicine(TCM)syndromes scores, tear film break-up time(BUT), Schirmer Ⅰ test(SⅠt), corneal fluorescein staining(FL)and quality of life [25-item National Eye Institute Visual Function Questionnaire(NEI-VFQ-25)]were compared between the two groups.RESULTS:After treatment, the total effective rate of treatment was 93% in observation group and was 75% in control group(P<0.05). …”
Get full text

Impacts of monocular, binocular, and functional visual acuity on vision-related quality of life in patients with type 2 diabetes by Kuo-Meng Liao, Wei-Chi Wu, Yuh Jang, Fan-Ya Su, Li-Ting Tsai

“…VRQoL and corrected VA were assessed with the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and Early Treatment Diabetic Retinopathy Study (ETDRS) chart, respectively. …”
Get full text

Multimodal Evaluation of Visual Function in Geographic Atrophy versus Normal Eyes by Burguera-Giménez N, García-Lázaro S, España-Gregori E, Gallego-Pinazo R, Burguera-Giménez N, Rodríguez-Vallejo M, Jonna G

“…Quality of life and vision were assessed with the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25).Results: Visual function and quality of life are reduced in patients with GA. …”
Get full text

Sex‐Specific Association of Obstructive Sleep Apnea With Retinal Microvascular Signs: The Multi‐Ethnic Study of Atherosclerosis by Gen‐Min Lin, Susan Redline, Ronald Klein, Laura A. Colangelo, Mary Frances Cotch, Tien Y. Wong, Barbara E. K. Klein, Sanjay R. Patel, Steven J. Shea, Kiang Liu

Get full text

Association of aquaporin-4 antibody-seropositive optic neuritis with vision-related quality of life and depression by Ruitong Song, Wenqiao Huang, Jun Yang, Xueshan Tang, Yihua Huang, Yingying Chen, Mukun Zhao, Qiuming Hu, Yi Du

“…However, the association between AQP4-ON and vision-related quality of life (QoL) and depression remains poorly understood.MethodsIn this cross-sectional study, 57 patients with optic neuritis were evaluated for their vision-related QoL using a Chinese version of the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) and assessed for depressive symptoms using a Chinese version of the Beck Depression Inventory-II (BDI-II). …”
Get full text

Tellurium Compounds Prevent and Reverse Type-1 Diabetes in NOD Mice by Modulating α4β7 Integrin Activity, IL-1β, and T Regulatory Cells by Tom Eitan Yossipof, Ziva Roy Bazak, Dvora Kenigsbuch-Sredni, Rachel R. Caspi, Yona Kalechman, Benjamin Sredni

Get full text

No improvement in injection frequency or in visual outcome over time in two cohorts of patients from the same Swedish county treated for wet age-related macular degeneration by Schroeder M, Rung L, Lövestam-Adrian M

“…Visual acuity (VA) was examined by Early Treatment Diabetic Retinopathy Study (ETDRS) charts. The National Eye Institute Visual Functioning Questionnaire 25 was answered by patients at baseline and at 37&plusmn;7 months (cohort 1) and at 45&plusmn;4 months (cohort 2). …”
Get full text

Microarray analysis of microRNA expression in the developing mammalian brain by Miska, Eric A., Alvarez-Saavedra, Ezequiel, Yoshii, Akira, Sestan, Nenad, Rakic, Pasko, Constantine-Paton, Martha, Horvitz, H. Robert, Townsend, Matthew R.

Get full text
Get full text
Get full text

Object decoding with attention in inferior temporal cortex by Zhang, Ying, Meyers, Ethan M., Bichot, Narcisse Pascal, Serre, Thomas R., Poggio, Tomaso A., Desimone, Robert

Get full text
Get full text
Get full text
Get full text

Using point process models to compare neural spiking activity in the nucleus of Parkinson's patients and a healthy primate by Sarma, Sridevi V., Eden, Uri T., Cheng, Ming L., Williams, Ziv M., Hu, Rollin, Eskandar, Emad, Brown, Emery N.

Get full text
Get full text

The ASCEND-Eye study: effect(s) of aspirin and omega-3 fatty acids on eye disease by Sammons, E

“…</p></br> <p><strong>Methods</strong></p> <p>Events were derived from three sources: 1) six-monthly follow-up questionnaires for ASCEND or a one-off eye questionnaire sent to a subset of participants after the parent trial ended, 2) electronic NHS Diabetic Eye Screening Programme (DESP) data and 3) responses to the National Eye Institute’s Visual Function Questionnaire-25 (NEI-VFQ-25). …”

بررسی کیفیت زندگی بیماران مبتلا به Retinitis Pigmentosa (RP) در شهر شیراز by فاطمه عزیزی, محمد آقازاده امیری, عباس ریاضی, حسین نوروززاده, سید مهدی طباطبایی

“…افراد شرکت­کننده نسخه فارسی پرسش­نامه 25 گزینه­ای National Eye Institute Visual Function Questionnare-25 (NEI VFQ-25) را پاسخ دادند. …”
Get full text

Early changes in macular optical coherence tomography parameters after Ranibizumab intravitreal injection in patients with exsudative age-related macular degeneration by Nicole Antunes de Almeida, Osias Francisco de Souza

“…The patients were evaluated on the first day, them at 7 and 30 days after the treatment. The National Eye Institute Visual Functioning Questionnaire was applied during the study period to assess early perception of ranibizumab injection effectiveness. …”
Get full text

The Effect of Visual Impairment and Its Severity on Vision-Related and Health-Related Quality of Life in Jordan: A Comparative Cross-Sectional Study by Jammal HM, Khader Y, Kanaan SF, Al-Dwairi R, Mohidat H, Al-Omari R, Alqudah N, Saleh OA, Alshorman H, Al Bdour M

“…An interviewer administered the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and the Medical Outcomes Study 12-Item Short Form Health Survey (SF-12) to all participants.Results: All the mean VFQ-25 subscales scores, physical component scale (PCS) and the mental component scale (MCS) of the SF-12 were significantly lower in patients with VI compared to controls with no VI. …”
Get full text