Dry eye symptom questionnaires show adequate measurement precision and psychometric validity for clinical assessment of vision-related quality of life in glaucoma patients. by Stephen Ocansey, Ebenezer Oduro Antiri, Carl Haladay Abraham, Emmanuel Kwasi Abu

“…All the participants underwent dry eye examination and completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), the Dry Eye-related Quality of Life Score (DEQS) and the Ocular Surface Disease Index (OSDI). …”
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Prospective, Longitudinal Pilot Study by Tiarnan D.L. Keenan, BM BCh, PhD, Michaella Goldstein, MD, Dafna Goldenberg, MD, Dinah Zur, MD, Shiri Shulman, MD, Anat Loewenstein, MD

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Anti-Saccades in Cerebellar Ataxias Reveal a Contribution of the Cerebellum in Executive Functions by Elena Pretegiani, Elena Pretegiani, Pietro Piu, Francesca Rosini, Francesca Rosini, Pamela Federighi, Pamela Federighi, Valeria Serchi, Gemma Tumminelli, Gemma Tumminelli, Maria Teresa Dotti, Antonio Federico, Alessandra Rufa, Alessandra Rufa

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Clinical, social, and policy factors in COVID-19 cases and deaths: methodological considerations for feature selection and modeling in county-level analyses by Charisse Madlock-Brown, Ken Wilkens, Nicole Weiskopf, Nina Cesare, Sharmodeep Bhattacharyya, Naomi O. Riches, Juan Espinoza, David Dorr, Kerry Goetz, Jimmy Phuong, Anupam Sule, Hadi Kharrazi, Feifan Liu, Cindy Lemon, William G. Adams

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A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema by Noemi Lois, Evie Gardner, Margaret McFarland, David Armstrong, Christine McNally, Nuala Jane Lavery, Christina Campbell, Rita I Kirk, Daiva Bajorunas, Ann Dunne, Anthony Cerami, Michael Brines

“…There was no improvement in mean change baseline-week 12 in BCVA (−2.9 + 5.0), CRT (10 + 94.6 microns), central retinal sensitivity (−0.53 + 1.9 dB) or tear production (−0.13 + 7.7 mm), but there was an improvement in National Eye Institute Visual Function Questionnaire (NEI VFQ-25) composite scores (2.7 + 3.1). …”
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Retinal vessel caliber and cognitive performance: the multi-ethnic study of atherosclerosis (MESA) by Nada El Husseini, Christopher L. Schaich, Suzanne Craft, Stephen R. Rapp, Kathleen M. Hayden, Richey Sharrett, Mary Frances Cotch, Tien Y. Wong, Jose A. Luchsinger, Mark A. Espeland, Laura D. Baker, Alain G. Bertoni, Timothy M. Hughes

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Ophthalmic sequelae and psychosocial impact in pediatric ebola survivors by Jessica G. Shantha, Dominick Canady, Caleb Hartley, Amy Cassedy, Chris Miller, Sheila T. Angeles-Han, Lloyd C.M. Harrison-Williams, Matthew J. Vandy, Natalie Weil, Gilberte Bastien, Steven Yeh

“…Funding: National Institutes of Health R01 EY029594, K23 EY030158; National Eye Institute; Research to Prevent Blindness (Emory Eye Center); Marcus Foundation Combating Childhood Illness; Emory Global Health Institute; Stanley M. …”
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Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of FcεRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels by Hima Dhakal, Hima Dhakal, Soyoung Lee, Eun-Nam Kim, Jin Kyeong Choi, Min-Jong Kim, Jinjoo Kang, Young-Ae Choi, Moon-Chang Baek, Byungheon Lee, Hyun-Shik Lee, Tae-Yong Shin, Gil-Saeng Jeong, Sang-Hyun Kim, Sang-Hyun Kim

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Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device by Thanh-Tin P. Nguyen, Shuibin Ni, Shuibin Ni, Guangru Liang, Guangru Liang, Shanjida Khan, Shanjida Khan, Xiang Wei, Xiang Wei, Alison Skalet, Alison Skalet, Alison Skalet, Alison Skalet, Susan Ostmo, Michael F. Chiang, Yali Jia, Yali Jia, David Huang, David Huang, Yifan Jian, Yifan Jian, J. Peter Campbell

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Glaucomatous visual fields and neurocognitive function are independently associated with poor lane maintenance during driving simulation by David E. Anderson, John P. Bader, Emily A. Boes, Meghal Gagrani, Lynette M. Smith, Jideofor K. Ndulue, Sachin Kedar, Vikas Gulati, Deepta A. Ghate, Matthew Rizzo

“…Montreal Cognitive Assessment (MoCA) was administered to assess global and sub-domain neurocognitive performance. National Eye Institute Visual Function Questionnaire (NEI-VFQ) was administered to assess peripheral vision and driving difficulties sub-scores. …”
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Comparison of visual outcomes after bilateral implantation of two intraocular lenses with distinct diffractive optics by de Medeiros AL, Jones Saraiva F, Iguma CI, Kniggendorf DV, Alves G, Chaves MAPD, Vilar C, Motta AFP, Carricondo PC, Takashi Nakano C, Nosé W, Hida WT

“…Ophthalmological evaluation included the measurement of binocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected near visual acuity (UNVA) at 40 cm, uncorrected intermediate visual acuity (UIVA) at 70 cm, monocular visual defocus curve and the quality of life (QoL) questionnaire, National Eye Institute Visual Functioning Questionnaire - 25 ( NEI-VFQ 25).Results: Postoperative UDVA was 0.00 and 0.09 logMAR (P<0.001), UIVA was 0.20 and 0.39 logMAR (P<0.001) and UNVA was 0.16 and −0.01 logMAR (P<0.001) in groups A and B, respectively; postoperative CDVA was −0.05 and 0.06 logMAR (P<0.001) in groups A and B, respectively.Conclusion: Both groups reported good subjective quality of vision regarding long, intermediate and short distances. …”
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A randomized multicenter study comparing seawater washes and carmellose artificial tears eyedrops in the treatment of dry eye syndrome by Diaz-Llopis M, Pinazo-Duran MD, Diaz-Guiñon L, Rahhal-Ortuño M, Perez-Ramos M, Bosch R, Gallego-Pinazo R, Dolz-Marco R, Diaz-Guiñon T, Diaz M, Romero FJ, Cisneros A

“…The parameters studied and measured were as follows: Ocular Surface Disease Index questionnaire score, Schirmer I test (without anesthesia) score, tear osmolarity (TearLab®), tear breakup time, tear meniscus height (meniscography OCT), fluorescein corneal staining score (National Eye Institute scale), lissamine green conjunctival staining score, and levels of IL-1 beta and IL-6 in tears (Luminex® 200). …”
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Multi-parametric evaluation of autologous cultivated Limbal epithelial cell transplantation outcomes of Limbal stem cell deficiency due to chemical burn by Ozlem Barut Selver, Mehmet Gurdal, Ayse Yagci, Sait Egrilmez, Melis Palamar, Turker Cavusoglu, Ali Veral, Cagri Guven, Utku Ates, Zheng Wang, J. Mario Wolosin

“…Subjective scores were based on patient answers to a) perception of visual improvement/pain; b) the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ 25); and c) the 12-item Ocular Surface Disease Index Questionnaire (OSDI). …”
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Evaluation of the psychological effect and vision related quality of life enucleated/eviscerated patients with prosthetic eyes by Royan, Jeyarine Monica Joan Poopal

“…Methods: A cross sectional study was conducted between March 2017 and March 2018 involving patients with prosthetic eyes post evisceration or enucleation attending eye clinics of two tertiary hospitals in Malaysia; Hospital Selayang and Hospital Universiti Sains Malaysia.The patients were given two validated questionnaires: The National Eye Institute Visual Function Questionnaire – (NEI-VFQ) and the Hospital Anxiety and Depression (HADS) questionnaire. …”
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Pseudophakia and Lens Opacities in 70-Year-Olds in Gothenburg, Sweden; Gender Differences, Impact on Self-Reported Visual Function and Validation of Self-Reported Cataract and Pseu... by Nordström M, Holm M, Havstam Johansson L, Rydberg Sterner T, Ahlner F, Falk Erhag H, Skoog I, Zetterberg M

“…A total of 1139 subjects completed the National Eye Institute Visual Functioning Questionnaire‐25 (NEI VFQ‐25), 560 subjects underwent ophthalmic examination including visual acuity and lens photography. t-test, Pearson chi-square and Mann–Whitney U-test were used for obtaining p-values. …”
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Infigratinib Reduces Fibroblast Growth Factor 23 (FGF23) and Increases Blood Phosphate in Tumor‐Induced Osteomalacia by Iris R. Hartley, Kelly L. Roszko, Xiaobai Li, Karen Pozo, Jamie Streit, Jaydira delRivero, M. Teresa Magone, Michaele R. Smith, Roo Vold, Carl L. Dambkowski, Michael T. Collins, Rachel I. Gafni

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Deepfakes in Ophthalmology by Jimmy S. Chen, MD, Aaron S. Coyner, PhD, R.V. Paul Chan, MD, M. Elizabeth Hartnett, MD, Darius M. Moshfeghi, MD, Leah A. Owen, MD, PhD, Jayashree Kalpathy-Cramer, PhD, Michael F. Chiang, MD, MA, J. Peter Campbell, MD, MPH

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BALATON and COMINO: Phase III Randomized Clinical Trials of Faricimab for Retinal Vein Occlusion by Lars-Olof Hattenbach, MD, PhD, Francis Abreu, PhD, Pablo Arrisi, PhD, Karen Basu, PhD, Carl J. Danzig, MD, Robyn Guymer, MD, PhD, Zdenka Haskova, MD, PhD, Jeffrey S. Heier, MD, Aachal Kotecha, PhD, Ying Liu, PhD, Anat Loewenstein, MD, András Seres, MD, Jeffrey R. Willis, MD, PhD, Charles C. Wykoff, MD, PhD, Liliana P. Paris, MD, PhD

“…Secondary end points (weeks 0–24) were mean change from baseline in BCVA, CST, and National Eye Institute Visual Function Questionnaire 25 composite score; proportion of patients gaining or avoiding loss of ≥ 15/≥ 10/≥ 5/> 0 letters. …”
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Transcutaneous Electrical Stimulation for the Prevention of Dry Eye Disease after Photorefractive Keratectomy by Gyule Han, MD, Dong Hui Lim, MD, PhD, Young Sik Yoo, MD, PhD, Eun Hye Shin, MD, Jong Yup Park, MD, Dohyoung Kim, PhD, Pyungkyu Kim, BS, Tae-Young Chung, MD, PhD

“…Dry eye signs were assessed using tear break-up time (TBUT), total corneal fluorescein staining (tCFS), and total conjunctival staining score according to the National Eye Institute/Industry scale. The pain intensity was evaluated using a visual analog scale. …”
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Patient-Reported Health-Related Quality of Life in Individuals with Inherited Retinal Diseases by Deborah Schofield, PhD, Joshua Kraindler, MSc, Owen Tan, MComm, Rupendra Shrestha, PhD, Diana Jelovic, BAppSci, Sarah West, MBMSc, Alan Ma, PhD, FRACP, John Grigg, MD, FRANZCO, Robyn V. Jamieson, PhD, FRACP

“…Linear regressions were used to analyze the relationship between the 25-item and 39-item National Eye Institute Visual Function Questionnaires (NEI-VFQ-25 and NEI-VFQ-39, respectively) and health utilities from the AQoL-8D. …”
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