Cross-sectional analysis of use of real-world data in single technology appraisals of oncological medicine by the National Institute for Health and Care Excellence in 2011–2021 by Jiyeon Kang, John Cairns

“…Objectives This study aims to identify how real-world data (RWD) have been used in single technology appraisals (STAs) of cancer drugs by the National Institute for Health and Care Excellence (NICE).Design Cross-sectional study of NICE technology appraisals of cancer drugs for which guidance was issued between January 2011 and December 2021 (n=229). …”
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Prognostic value of acute National Institutes of Health Stroke Scale Items on disability: a registry study of first-ever stroke in the western part of Sweden by Katharina S Sunnerhagen, Hege Ihle Hansen, Tamar Abzhandadze, Haakon Ihle-Hansen, Guri Hagberg, Malin Reinholdsson

“…Objectives We aimed to study how the individual items of the National Institutes of Health Stroke Scale (NIHSS) at admission predict functional independence 3 months post-stroke in patients with first-ever stroke.Setting This registry-based study used data from two Swedish stroke registers (Riksstroke, the mandatory national quality register for stroke care in Sweden, and Väststroke, a local quality stroke register in Gothenburg).Participants This study included patients with first-ever acute stroke admitted from November 2014 to August 2018, with available NIHSS at admission and modified Rankin Scale (mRS) at 3-month follow-up.Primary outcome The primary outcome variable was mRS≤1 (defined as an excellent outcome) at 3-month follow-up.Results We included 1471 patients, mean age was 72 (± 14.5) years, 48% were female, and 66% had mild strokes (NIHSS≤3). …”
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National Institutes of Health-sponsored clinical islet transplantation consortium phase 3 trial: Manufacture of a complex cellular product at eight processing facilities. by Ricordi, C, Goldstein, J, Balamurugan, A, Szot, G, Kin, T, Liu, C, Czarniecki, C, Barbaro, B, Bridges, N, Cano, J, Clarke, W, Eggerman, T, Hunsicker, L, Kaufman, D, Khan, A, Lafontant, D, Linetsky, E, Luo, X, Markmann, J, Naji, A, Korsgren, O, Oberholzer, J, Turgeon, N, Brandhorst, D, Chen, X, Friberg, A, Lei, J, Wang, L, Wilhelm, J, Willits, J, Zhang, X, Hering, B, Posselt, A, Stock, P, Shapiro, A, Chen, X

“…Eight manufacturing facilities participating in the National Institutes of Health-sponsored Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a harmonized process for the manufacture of allogeneic purified human pancreatic islet (PHPI) product evaluated in a phase 3 trial in subjects with type 1 diabetes. …”

Markers of achievement for assessing and monitoring gender equity in a UK National Institute for Health Research Biomedical Research Centre: A two-factor model by Henderson, LR, Shah, SGS, Ovseiko, PV, Dam, R, Buchan, AM, McShane, H, Kiparoglou, V

“…Biomedical Research Centres (BRC), partnerships between leading National Health Service (NHS) organisations and universities, conduct world class translational research funded by the National Institute for Health Research (NIHR) in the UK. Since 2011 BRCs are required to demonstrate significant progress in gender equity (GE) to be eligible to apply for funding. …”

Markers of achievement for assessing and monitoring gender equity in a UK National Institute for Health Research Biomedical Research Centre: a two-factor model by Henderson, LR, Shah, SGS, Ovseiko, PV, Dam, R, Buchan, AM, McShane, H, Kiparoglou, V

“…Biomedical Research Centres (BRC), partnerships between leading National Health Service (NHS) organisations and universities, conduct world class translational research funded by the National Institute for Health Research (NIHR) in the UK. Since 2011 BRCs are required to demonstrate significant progress in gender equity (GE) to be eligible to apply for funding. …”

Setting research priorities for global respiratory medicine within the National Institute for Health Research (NIHR) Global Health Research Unit in Respiratory Health (RESPIRE) by Rudan, Igor, Agrawal, Dhiraj, Hussein, Norita, Ai, Theng Cheong, Cunningham, Steve, Dockerell, David, Shariff Ghazali, Sazlina, Ghorpade, Deesha, Habib, Monsur, Hazir, Tabish, Juvekar, Sanjay, Kawade, Anand, Ping, Yein Lee, Su, May Liew, Luz, Saturnino, Ee, Ming Khoo, Nair, Harish, Norrie, John, Patil, Rutuja, Pinnock, Hilary, Ramdzan, Siti Nurkamilla, Roy, Sudipto, Salim, Hani, Smith, Pam, Mahmood Yahya, Hana, Williams, Sian, Campbell, Harry, Sheikh, Aziz

Approaches to optimising access to NICE-approved biologic anti-TNFs for patients with rheumatoid arthritis with moderately active disease by Peter C. Taylor, Ayman Askari, Ernest Choy, Michael R. Ehrenstein, Sara Else, Muhammad K. Nisar

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Evaluation of the National Institutes of Health–supported relative citation ratio among American orthopedic spine surgery faculty: A new bibliometric measure of scientific influence by Christopher N. Dijanic, Suleiman Y. Sudah, Christopher R. Michel, Tiffany A. Smith, Aneesh Patankar, Joseph E. Manzi, Robert D Faccone, Daniel J. Kerrigan, Mariano E. Menendez, Jason Cohen

“…However, traditional bibliometrics lack field-normalization and are often biased towards time-dependent publication factors. The National Institutes of Health (NIH) has developed a new, field-normalized, article-level metric, known as the “relative citation ratio” (RCR), that can be used to make accurate self, departmental, and cross-specialty comparisons of research productivity. …”
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Research Priorities for Pediatric Intensive Care Nutrition Within the United Kingdom: A National Institute of Health Research James Lind Alliance Priority Setting Partnership by Graeme O’Connor, RD, PHD, Luise V. Marino, RD, PHD, Lyvonne N. Tume, RN, PHD, Alexandra Stewart, RCSLT, Simon Gates, BSC, Julie Lanigan, RD, PHD, Harish Bangalore, MBBS, MRCPCh, Suzannah Kinsella, BSC

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Glucagon-like Peptide-1 Receptor Agonists Associated Gastrointestinal Adverse Events: A Cross-Sectional Analysis of the National Institutes of Health All of Us Cohort by Wafa Ali Aldhaleei, Tadesse M. Abegaz, Akshaya Srikanth Bhagavathula

“…Methods: This retrospective cross-sectional analysis utilized real-world data on 10,328 adults with diabetes/obesity in the National Institutes of Health All of Us cohort. New GLP-1 RA users were identified, and GI adverse events were examined. …”
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HSCRP predicts mortality beyond Troponin in 102,337 patients with suspected acute coronary syndrome in the UK National Institute for Health Research CRP-risk study by Kaura, A, Hartley, A, Panoulas, V, Benjamin, G, Davies, J, Woods, K, Mulla, A, Shah, AD, Channon, K, Weber, JN, Thursz, MR, Elliott, P, Hemingway, H, Williams, B, Asselbergs, FW, Kharbanda, R, Lord, GM, Melikian, N, Patel, R, Perera, D, Shah, A, Francis, D, Koenig, W, Mayet, J, Khamis, R

Co-producing an online patient public community research hub: a qualitative study exploring the perspectives of national institute for health research (NIHR) research champions in England by Eleanor Hoverd, Sophie Staniszewska, Jeremy Dale, Rachel Spencer, Anne Devrell, Dena Khan, Carrol Lamouline, Sanya Saleem, Pam Smith

“…Methods This project involved working as partners with five National Institute for Health and Care Research (NIHR) Research Champions. …”
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Development and validation of a novel clinical prediction model to predict the 90-day functional outcome of spontaneous intracerebral hemorrhage by Zhi Geng, Zhi Geng, Zhi Geng, Tao Guo, Ziwei Cao, Xiaolu He, Jing Chen, Hong Yue, Aimei Wu, Lichao Wei, Lichao Wei, Lichao Wei, Lichao Wei

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Relationship Between the National Institutes of Health Chronic Prostatitis Symptom Index and the International Prostate Symptom Score in Middle-Aged Men According to the Presence of Chronic Prostatitis-Like Symptoms by Min Ho Lee, Deok Ha Seo, Chunwoo Lee, Jae Hwi Choi, Seong Uk Jeh, Sin Woo Lee, See Min Choi, Jeong Seok Hwa, Jae Seog Hyun, Ky Hyun Chung, Sung Chul Kam

“…Patients with CP often complain of lower urinary tract symptoms (LUTS); however, the voiding domain of the Chronic Prostatitis Symptom Index of the National Institutes of Health (NIH-CPSI) is not sufficient to evaluate LUTS. …”
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Getting our house in order: an audit of the registration and publication of clinical trials supported by the National Institute for Health Research Oxford Biomedical Research Centre and the Musculoskeletal Biomedical Research Unit. by Tompson, A, Petit-Zeman, S, Goldacre, B, Heneghan, C

“…To audit the proportion of clinical trials that had been publically registered and, of the completed trials, the proportion published.2 major research institutions supported by the National Institute of Health Research (NIHR).The proportion of trials reporting results within 12 months, 24 months and 'ever'. …”

Immunologic aspects of chronic fatigue syndrome. Report on a Research Symposium convened by The CFIDS Association of America and co-sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health. by Gerrity, T, Papanicolaou, D, Amsterdam, J, Bingham, S, Grossman, A, Hedrick, T, Herberman, R, Krueger, G, Levine, S, Mohagheghpour, N, Moore, R, Oleske, J, Snell, C

Descriptors of sepsis using the Sepsis-3 criteria: A cohort study in critical care units within the UK National Institute for Health Research Critical Care Health Informatics Collaborative by Shah, AD, MacCallum, NS, Harris, S, Brealey, DA, Palmer, E, Hetherington, J, Shi, S, Perez-Suarez, D, Ercole, A, Watkinson, PJ, Jones, A, Ashworth, S, Beale, R, Brett, SJ, Singer, M

“…National Health Service hospital trusts contributing to the National Institute for Health Research Critical Care Health Informatics Collaborative. …”

Paramedic Norwegian Acute Stroke Prehospital Project (ParaNASPP) study protocol: a stepped wedge randomised trial of stroke screening using the National Institutes of Health Stroke Scale in the ambulance by Helge Fagerheim Bugge, Mona Guterud, Kristi C. G. Bache, Anne-Cathrine Braarud, Erik Eriksen, Kjell Otto Fremstad, Hege Ihle-Hansen, Svein Håkon Ingebretsen, Jo Kramer-Johansen, Karianne Larsen, Jo Røislien, Kjetil Thorsen, Mathias Toft, Else Charlotte Sandset, Maren Ranhoff Hov

“…Prehospital stroke scales are developed for quick and easy identification of stroke, but have poor sensitivity and specificity compared to an in-hospital assessment with the National Institutes of Health Stroke Scale (NIHSS). The aim of the Paramedic Norwegian Acute Stroke Prehospital Project (ParaNASPP) is to assess whether a structured learning program, prehospital NIHSS and a mobile application facilitating communication with the stroke physician may improve triage of acute stroke patients. …”
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Patterns of progression differ between Kellgren-Lawrence 2 and 3 knees fulfilling different definitions of a cartilage-meniscus phenotype in the Foundation for National Institutes of Health Osteoarthritis Biomarkers study (FNIH) by Frank W. Roemer, Jamie E. Collins, David J. Hunter, Shadpour Demehri, Ali Guermazi

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Application of the National Institute for Health and Care Excellence Evidence Standards Framework for Digital Health Technologies in assessing mobile-delivered technologies for the self-management of type 2 diabetes mellitus: scoping review by Forsyth, JR, Chase, H, Roberts, NW, Armitage, LC, Farmer, AJ

“…In 2019, the National Institute for Health and Care Excellence (NICE) published the NICE Evidence Standards Framework for DHTs. …”