Group B meningococcal vaccine science and policy by Drysdale, SB, Pollard, A

“…Capsular group B Neisseria meningitidis is one of the leading causes of death in developed countries. …”

Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. by Darton, T, Guiver, M, Naylor, S, Kaczmarski, E, Borrow, R, Read, R

“…Among 384 patients with confirmed meningococcal disease, the likelihood of detecting Neisseria meningitidis DNA in cerebrospinal fluid (CSF) increased with age, serogroup B infection, and prehospitalization antibiotic treatment. …”

Análise epidemiológica da meningite bacteriana no Estado do Amapá nos anos de 2013 a 2018 by Lissandra Gomes Pimentel, Ítalo Bruno Maciel Campos, Keren Hapuque da Silva Souza, Diego Henrique de Souza Monte de Almeida

“…Seus principais agentes etiológicos bacterianos são Neisseria meningitidis, Streptococcus pneumoniae e Haemophilus influenzae. …”
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The Diverse Spectrum of Invasive Meningococcal Disease in Pediatric and Adolescent Patients: Narrative Review of Cases and Case Series by Shravani Bobde, Woo-Yun Sohn, Rafik Bekkat-Berkani, Angelika Banzhoff, Athena Cavounidis, Ener Cagri Dinleyici, Wilfrido Coronell Rodriguez, Nelly Ninis

“…Abstract Introduction Invasive meningococcal disease (IMD) is a potentially life-threatening disease caused by Neisseria meningitidis infection. We reviewed case reports of IMD from newborns, infants, children, and adolescents, and described the real-life clinical presentations, diagnoses, treatment paradigms, and clinical outcomes. …”
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Practical Management for Use of Eculizumab in the Treatment of Severe, Refractory, Non-Thymomatous, AChR + Generalized Myasthenia Gravis: A Systematic Review [Erratum] by Waheed W, Newman E, Aboukhatwa M, Moin M, Tandan R

“…The value “1200 mg” in the Neisseria meningitidis vaccination row for the Induction Phase, Week 4 column for Refractory gMG Adult (≥18 years of age) Dosing Schedule, should read “900 mg”. …”
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Purulent cerebral meningitis presenting as eclampsia by A Okalawon Sule-Odu

“…The definite diagnosis of meningitis caused by Neisseria Meningitidis was made at postmortem. This is the only case of meningitis in pregnancy reported in the hospital in a period of ten years (1987 - 1996) with 7,300 and 6758 total deliveries and live birth respectively and 86 maternal deaths (11.8 per 1000 births). …”
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Epidemiology of meningococcal disease in north america. by Pollard, A, Scheifele, D, Rosenstein, N

“…Invasive disease caused by Neisseria meningitidis is one of the leading infectious causes of death in childhood in North America (1), but its prevention has not received the same priority on the health agenda as in Europe, Australia, and New Zealand. …”

Clinical studies : an overview. by Riordan, F, Pollard, A

“…Disease caused by Neisseria meningitidis is a worldwide problem (1). Epi- demics of meningococcal disease regularly occur in the "meningitis belt" of sub-Saharan Africa and in Asia (2-5) and high or increasing levels of endemic meningococcal disease have been reported recently in the UK (6), New Zealand (7), Cuba (8), Brazil (9), Norway (10), and the Pacific Northwest of the United States (11). …”

Mechanisms of meningococcal colonisation. by Trivedi, K, Tang, C, Exley, R

“…Despite advances against infectious diseases over the past century, Neisseria meningitidis remains a major causative agent of meningitis and septicaemia worldwide. …”

Invasive Meningococcal X Disease during the COVID-19 Pandemic, Brazil by Lucila O. Fukasawa, Bernadete L. Liphaus, Maria Gisele Gonçalves, Fabio T. Higa, Carlos H. Camargo, Telma R.M.P. Carvalhanas, Ana Paula S. Lemos

“…Although cases caused by Neisseria meningitidis serogroup X (MenX) occur infrequently, outbreaks have been reported in countries in Africa in recent decades. …”
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Quadrivalent meningococcal conjugate vaccines by Pace, D, Pollard, A, Messonier, N

“…<em>Neisseria meningitidis</em> is an important cause of bacterial meningitis and septicaemia with most disease caused by meningococci bearing serogroups A, B, C, Y and W-135 polysaccharides. …”

Bacterial meningitis in childhood. by Sadarangani, M, Pollard, A

“…Bacterial meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) is of particular importance as it has a high mortality and morbidity, has been relatively common and is treatable with antibiotics. …”

Evolution and exchange of plasmids in pathogenic Neisseria by Wearn-Xin Yee, Tabea Elsener, Ana Cehovin, Martin C. J. Maiden, Christoph M. Tang

“…Here, we show that pConj evolved in the related pathogen, Neisseria meningitidis, and has been acquired by the gonococcus from the meningococcus on multiple occasions. …”
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Vigilancia de eventos adversos de la vacuna plisacárida meningocócica A y C durante una campaña de vacunación en Níger by Meiby de la Caridad Rodríguez, Iván Edelberto Cuevas, Mayelín Mirabal, Luis Ruíz

“…La inmunoprofilaxis constituye la estrategia por excelencia para la prevención y control de las epidemias de meningitis meningocócica provocadas por el serogrupo A de Neisseria meningitidis en el llamado cinturón de la meningitis en África, donde alcanza altas tasas de morbimortalidad. …”
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Localized hypermutation is the major driver of meningococcal genetic variability during persistent asymptomatic carriage by Green, LR, Al-Rubaiawi, AA, Al-Maeni, MARM, Harrison, OB, Blades, M, Oldfield, NJ, Turner, DPJ, Maiden, MCJ, Bayliss, CD

“…Genetic variation was investigated during persistent asymptomatic carriage of Neisseria meningitidis. Interrogation of whole-genome sequences for paired isolates from 25 carriers showed that de novo mutations were infrequent, while horizontal gene transfer occurred in 16% of carriers. …”

To What Extent Should We Rely on Antibiotics to Reduce High Gonococcal Prevalence? Historical Insights from Mass-Meningococcal Campaigns by Chris Kenyon

“…To contribute to this debate, we assessed if mass treatment in the related species, <i>Neisseria meningitidis,</i> was associated with the emergence of antimicrobial resistance. …”
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Meningococcemia in an 11 Months Old Infant by Rachana Shrestha, Saurab Karki, Manoj Khadka, Suhail Sapkota, Bibek Timilsina, Sulochana Khadka

“…Meningococcemia is the infection of the blood caused by Neisseria meningitidis. Herein, we report a case of meningococcemia in an 11 months old infant who had a high-grade fever, nonblanching purpuric rash over the face and limbs, low blood pressure, tachycardia, and prolonged capillary refill time, but without neck rigidity and focal neurologic signs. …”
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Fulminans Purpura due to Morganella morganii by Mariana Guerra, Daniela Marado

“…The idiopathic/infectious form is the most common and usually associated with infection by Neisseria meningitidis or Streptococcus pneumoniae. We describe a case of Morganella morganii-induced bacteriaemia complicated with PF in an individual who had undergone a recent urinary tract infection intervention. …”
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Enter B and W: two new meningococcal vaccine programmes launched by Ladhani, S, Ramsay, M, Borrow, R, Riordan, A, Watson, J, Pollard, A

“…In 2015, the UK became the first country in the world to have a comprehensive routine meningococcal vaccine programme targeting all of the main capsular groups of N. meningitidis. 1 An infant vaccine programme against meningococcal capsular group B Neisseria meningitidis (MenB) was launched from 1st September with an aim to reduce endemic MenB disease in early childhood. …”

Trends in meningococcal disease: challenges for vaccine control when disease is rare by Pollard, A, Christensen, H

“…The clinical, social and economic value of vaccination varies both with time and by population group <br/> In most wealthy and in many middle income countries, capsular group B Neisseria meningitidis (MenB) remains an important cause of invasive disease, particularly in the era of control of other major bacterial pathogens, such as MenC, Haemophilus influenzae type b, and vaccine-type pneumococcus. …”