Immunological memory: the role of B cells in long-term protection against invasive bacterial pathogens. by Kelly, D, Pollard, A, Moxon, E

“…Protein-polysaccharide conjugate vaccines that protect against Haemophilus influenzae type b (Hib), serogroup C Neisseria meningitidis, and multiple capsular serotypes of Streptococcus pneumoniae have had a major impact on invasive bacterial disease in childhood when incorporated into routine infant immunization schedules. …”

Sustaining immunity after immunization against encapsulated bacteria. by Blanchard-Rohner, G, Pollard, A

“…Over the last 20 years protein-polysaccharide conjugate vaccines have been developed to protect against the major invasive bacterial diseases of childhood, Streptococcus pneumoniae, Haemophilus influenzae type b (Hib) and Neisseria meningitidis. These vaccines are highly immunogenic and have resulted in a huge reduction in the diseases caused by these bacteria in the countries that have introduced them in their immunisation schedules. …”

Serogroup B meningococcal vaccines-an unfinished story. by Sadarangani, M, Pollard, A

“…Most invasive meningococcal disease in developed countries is caused by Neisseria meningitidis with a serogroup B capsule. However, despite availability of vaccines for other serogroups since the 1960s, no serogroup B vaccine exists. …”

Membrane simulations of OpcA: gating in the loops? by Bond, P, Derrick, J, Sansom, MS

“…Molecular dynamics simulations of OpcA from Neisseria meningitidis, embedded in a lipid bilayer, have been used to explore the relationship between the crystal structure and dynamic function of this protein. …”

Transposon-like Correia elements: structure, distribution and genetic exchange between pathogenic Neisseria sp. by Buisine, N, Tang, C, Chalmers, R

“…Phylogenetic analysis suggests that their presence predates the divergence of Neisseria meningitidis and Neisseria gonorrhoeae.…”

Microsatellite instability regulates transcription factor binding and gene expression. by Martin, P, Makepeace, K, Hill, SA, Hood, D, Moxon, E

“…Phase-variable expression of NadA, an outer membrane protein and adhesin of the pathogen Neisseria meningitidis, is mediated by changes in the number of TAAA repeats located upstream of the core promoter of nadA. …”

Genetic bases of C7 deficiency: systematic review and report of a novel deletion determining functional hemizygosity by Andrea Balduit, Anna Monica Bianco, Alessandro Mangogna, Anna Maria Zicari, Lucia Leonardi, Bianca Laura Cinicola, Bianca Laura Cinicola, Martina Capponi, Alberto Tommasini, Alberto Tommasini, Chiara Agostinis, Adamo Pio d’Adamo, Adamo Pio d’Adamo, Roberta Bulla

“…Patients with terminal pathway C-deficiency have a 1,000- to 10,000-fold-higher risk of Neisseria meningitidis infections and should be therefore promptly identified to minimize the likelihood of further infections and to favor vaccination. …”
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Trends in laboratory-confirmed bacterial meningitis (2012–2019): national observational study, EnglandResearch in context by Sathyavani Subbarao, Sonia Ribeiro, Helen Campbell, Ifeanyichukwu Okike, Mary E. Ramsay, Shamez N. Ladhani

“…Data were extracted for positive bacterial cultures, PCR-positive results for Neisseria meningitidis or Streptococcus pneumoniae from cerebrospinal fluid and positive blood cultures in patients with clinical meningitis. …”
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Meningococcal surveillance in Southeast Asia and the Pacific by Helen S Marshall

“…Carriage rates of the causative bacteria, Neisseria meningitidis are also lower than in many other countries, with those of Asian ethnicity having a lower carriage prevalence than other ethnicities. …”
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Pneumococcal purpura fulminans in a 25-year-old patient with liver cirrhosis due to autoimmune hepatitis by Sarah J. Williamson, Rafael Ruiz-Gaviria

“…PF can be caused by acute infection, most commonly due to Neisseria meningitidis, followed by Streptococcus pneumoniae. …”
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Meningococcal Vaccines: Challenges and Prospects by Priyal Bagwe, Lotika Bajaj, Rikhav Gala, Susu M. Zughaier, Mohammad N. Uddin, Martin J. D’Souza

“…<i>Neisseria meningitidis</i> is a gram-negative bacterium that causes a severe acute infection, called the meningococcal disease [...]…”
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Title not available by Fábio Takenori Higa, Lucila Okuyama Fukasawa, Maria Gisele Gonçalves, Maristela Marques Salgado, Ana Paula Silva de Lemos, Lee H Harrison, Priscilla Lima de Oliveira, Carla Naufal da Silva, Claudio Tavares Sacchi

“…We evaluated the use of a newly described sodC-based real-time-polymerase chain reaction (RT-PCR) assay for detecting Neisseria meningitidis in normally sterile sites, such as cerebrospinal fluid and serum. …”
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Recent and Future Advances in the Chemoenzymatic Synthesis of Homogeneous Glycans for Bacterial Glycoconjugate Vaccine Development by Ayobami Adegbite, Pumtiwitt C. McCarthy

“…This review focuses on recent advances in the chemoenzymatic production of defined bacterial oligosaccharides for vaccine development with a focus on <i>Neisseria meningitidis</i> and selected WHO-prioritized antibacterial resistant-pathogens. …”
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A Syrian refugee with meningococcal empyema by Ozhan Akyol, Aslinur Ozkaya-Parlakay, Eda Uluman, Belgin Gulhan, Tugba Bedir Demirdag, Selin Nar-Otgun

“…Herein we report a 2-year-old Syrian refugee boy living in Turkey diagnosed with Neisseria meningitidis serotype B infection complicated with intracranial empyema. …”
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Epidemiological evidence for the role of the hemoglobin receptor, hmbR, in meningococcal virulence. by Harrison, O, Evans, N, Blair, J, Grimes, H, Tinsley, C, Nassif, X, Kriz, P, Ure, R, Gray, S, Derrick, J, Maiden, M, Feavers, I

“…The distribution of the hemoglobin receptor gene (hmbR) was investigated among disease and carriage Neisseria meningitidis isolates, revealing that the gene was detected at a significantly higher frequency among disease isolates than among carriage isolates. …”

Outer membrane vesicle vaccines by Micoli, F, MacLennan, CA

“…Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. …”

Long-term evolution of antigen repertoires among carried meningococci. by Buckee, C, Gupta, S, Kriz, P, Maiden, M, Jolley, K

“…For commensal organisms that occasionally cause disease, such as Neisseria meningitidis, however, the analysis of isolates from long-term asymptomatic carriage is necessary to elucidate their evolution and population structure. …”

Enter B and W: two new meningococcal vaccine programmes launched. by Ladhani, S, Ramsay, M, Borrow, R, Riordan, A, Watson, J, Pollard, A

“…In 2015, the UK became the first country in the world to have a comprehensive routine meningococcal vaccine programme targeting all of the main capsular groups of N. meningitidis. 1 An infant vaccine programme against meningococcal capsular group B Neisseria meningitidis (MenB) was launched from 1st September with an aim to reduce endemic MenB disease in early childhood. …”

Meningococcal A, C, Y and W-135 polysaccharide-protein conjugate vaccines. by Pace, D, Pollard, A

“…This article discusses the different glycoconjugate meningococcal vaccines which have been developed and the potential for their use to control disease caused by serogroups A, C, Y and W-135 of Neisseria meningitidis.…”

Experience with MCV-4, a meningococcal, diphtheria toxoid conjugate vaccine against serogroups A, C, Y and W-135. by Keyserling, H, Pollard, A, DeTora, L, Gilmet, G

“…Invasive disease due to Neisseria meningitidis continues to cause debility and death worldwide in otherwise healthy individuals. …”