Analysis of pilus biogenesis genes in bacteria expressing type iv pili by Saeed AHMED, Ijaz AHMAD, Shakoor AHMAD, Zahir SHAH, Muqadar SHAH, Farhan Anwar KHAN, Ijaz AHMAD

“…The structural and sequences similarities of type-IV pili proteins were analysed in Pseudomonas aeruginosa, Vibrio cholerae, Neisseria meningitidis and Neisseria gonorrhoeae. Pathogenic Neisseria species possess pili-genes that code structural and assembly proteins of type-IV pili. …”
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Dendrimers as Antimicrobial Agents in the Central Nervous System Infections. A Review by Kucková Katarína, Bhide Mangesh

“…Streptococcus pneumoniae and Neisseria meningitidis are the most common pathogens causing meningeal inflammation in Europe. …”
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Inference of transmission dynamics and retrospective forecast of invasive meningococcal disease. by Jaime Cascante-Vega, Marta Galanti, Katharina Schley, Sen Pei, Jeffrey Shaman

“…The pathogenic bacteria Neisseria meningitidis, which causes invasive meningococcal disease (IMD), predominantly colonizes humans asymptomatically; however, invasive disease occurs in a small proportion of the population. …”
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Meningococcal disease in adolescents and young adults: a review of the rationale for prevention through vaccination by Cynthia Burman, Lidia Serra, Charles Nuttens, Jessica Presa, Paul Balmer, Laura York

“…Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is characterized by high mortality and morbidity. …”
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Impact of Meningococcal ACWY Vaccination Program during 2017–18 Epidemic, Western Australia, Australia by Krist Ewe, Parveen Fathima, Paul Effler, Carolien Giele, Peter Richmond

“… The rising incidence of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup W in Western Australia, Australia, presents challenges for prevention. …”
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Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021–2022 by Timothy J. Doyle, Megan Gumke, Danielle Stanek, Joshua Moore, Brian Buck, Timothy Locksmith, Kelly Tomson, Sarah Schmedes, George Churchwell, Shan Justin Hubsmith, Baskar Krishnamoorthy, Karalee Poschman, Brandi Danforth, Daniel Chacreton

“…The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. …”
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Community-acquired septicaemia in southern Viet Nam: the importance of multidrug-resistant Salmonella typhi. by Hoa, N, Diep, T, Wain, J, Parry, C, Hien, T, Smith, MD, Walsh, A, White, N

“…Other Salmonella spp. (1%), Pseudomonas aeruginosa (1%), Neisseria meningitidis (0.5%) and Haemophilus influenzae (0.2%) were uncommon. …”

Genetic analysis of meningococci carried by children and young adults. by Claus, H, Maiden, M, Wilson, D, McCarthy, N, Jolley, K, Urwin, R, Hessler, F, Frosch, M, Vogel, U

“… BACKGROUND: Neisseria meningitidis is a diverse commensal bacterium that occasionally causes severe invasive disease. …”

Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease. by Callaghan, M, Rockett, K, Banner, C, Haralambous, E, Betts, H, Faust, S, Maiden, M, Kroll, J, Levin, M, Kwiatkowski, D, Pollard, A

“…Adhesion between the opacity-associated adhesin (Opa) proteins of Neisseria meningitidis and human carcino-embryonic antigen cell adhesion molecule (CEACAM) proteins is an important stage in the pathogenesis of meningococcal disease, a globally important bacterial infection. …”

The impact of nucleotide sequence analysis on meningococcal vaccine development and assessment by Maiden, MCJ

“…Here, the impact of sequencing on the field of vaccinology will be illustrated with reference to the development and implementation of vaccines against Neisseria meningitidis (the meningococcus) over the 30-year period from the late-1980s to the late-2010s. …”

Aetiologies of central nervous system infections in adults in Kathmandu, Nepal: a prospective hospital-based study by Giri, A, Arjyal, A, Koirala, S, Karkey, A, Dongol, S, Thapa, S, Shilpakar, O, Shrestha, R, Van Tan, L, Thi Thuy Chinh, B, Krishna K C, R, Pathak, K, Shakya, M, Farrar, J, Van Doorn, H, Basnyat, B

“…The bacterial pathogens identified were Neisseria meningitidis (n = 6); Streptococcus pneumoniae (n = 5) and Staphylococcus aureus (n = 2) in 13/87(14%). …”

Characterization of capsule genes in non-pathogenic Neisseria species by Clemence, M, Maiden, M, Harrison, O

“…The genus Neisseria comprises a diverse group of commensal bacteria, which typically colonize the mucosal surfaces of humans and other animals. Neisseria meningitidis, the meningococcus, is notable for its potential to cause invasive meningococcal disease (IMD) in humans; however, IMD is comparatively rare, and meningococci normally colonize the nasopharynx asymptomatically. …”

The influence of IS1301 in the capsule biosynthesis locus on meningococcal carriage and disease. by Kugelberg, E, Gollan, B, Farrance, C, Bratcher, H, Lucidarme, J, Ibarz-Pavon, AB, Maiden, M, Borrow, R, Tang, C

“…Previously we have shown that insertion of IS1301 in the sia/ctr intergenic region (IGR) of serogroup C Neisseria meningitidis (MenC) isolates from Spain confers increased resistance against complement-mediated killing. …”

The evolution of genetic structure in the marine pathogen, Vibrio vulnificus. by Bisharat, N, Cohen, D, Maiden, M, Crook, D, Peto, T, Harding, R

“…The role of recombination relative to mutation in the generation of new MLST variants of V. vulnificus within the clusters is comparable to that of other highly recombining bacteria such as Neisseria meningitidis. However, across the divide between the two major clusters of V. vulnificus strains, there is substantial linkage disequilibrium, lower estimates for recombination rates and shorter estimates of recombination tract length. …”

Variation in the Neisseria lactamica porin, and its relationship to meningococcal PorB. by Bennett, J, Callaghan, M, Derrick, J, Maiden, M

“…One potential vaccine strategy in the fight against meningococcal disease involves the exploitation of outer-membrane components of Neisseria lactamica, a commensal bacterium closely related to the meningococcus, Neisseria meningitidis. Although N. lactamica shares many surface structures with the meningococcus, little is known about the antigenic diversity of this commensal bacterium or the antigenic relationships between N. lactamica and N. meningitidis. …”

Characterizing the diversity and commensal origins of penA mosaicism in the genus Neisseria by Unitt, A, Maiden, M, Harrison, O

“…This contrasted with Neisseria meningitidis penA, for which the primary source of recombinant DNA was other meningococci, followed by Neisseria lactamica. …”

An Observational Study to Assess the Effectiveness of 4CMenB against Meningococcal Disease and Carriage and Gonorrhea in Adolescents in the Northern Territory, Australia—Study Prot... by Helen S. Marshall, Prabha H. Andraweera, James Ward, John Kaldor, Ross Andrews, Kristine Macartney, Peter Richmond, Vicki Krause, Ann Koehler, David Whiley, Lynne Giles, Rosalind Webby, Heather D’Antoine, Jonathan Karnon, Rob Baird, Andrew Lawrence, Helen Petousis-Harris, Philippe De Wals, Belinda Greenwood-Smith, Michael Binks, Lisa Whop

“…An oropharyngeal swab will be collected at baseline and 12 months to detect pharyngeal carriage of <i>Neisseria meningitidis</i> by PCR. The main methodological approaches to assess the effect of 4CMenB involve a nested case control analysis and screening method to assess vaccine effectiveness and an Interrupted Time Series regression analysis to assess vaccine impact. …”
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Adesão às novas vacinas conjugadas. Vacina anti-meningocócica e anti-pneumocócica. by Laurinda De Queirós, Luis Castro, Maria Carmo Ferreira, Guilherme Gonçalves

“…In order to assess the coverage with these new vaccines against Neisseria meningitidis and Streptococcus pneumoniae, we conducted a descriptive study of the cohort born in 1999, using a convenience sample, from eight health centres in the North of Portugal. …”
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Frequency of myocarditis in cases of fatal meningococcal infection in children: observations on 31 cases studied at autopsy by Garcia Norma S., Castelo Jane S., Ramos Valmin, Rezende Greyce S.M., Pereira Fausto E.L.

“…The diagnosis was confirmed by isolation of Neisseria meningitidis . At least three sections of fragments of both atria and ventricles were studied using the Dallas Criteria for the morphologic diagnosis of myocarditis. …”
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Bacterial Meningitis in Children: Neurological Complications, Associated Risk Factors, and Prevention by Abdulwahed Zainel, Hana Mitchell, Manish Sadarangani

“…There are three vaccine preventable causes: <i>Haemophilus influenzae</i> type b (Hib), <i>S. pneumoniae,</i> and <i>Neisseria meningitidis.</i> Starting antibiotics without delay is also critical to reduce the risk of neurological complications. …”
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