The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia. by Plüddemann, A, Hoe, J, Makepeace, K, Moxon, E, Gordon, S

“…Macrophage Scavenger Receptor A (SR-A) is a major non-opsonic receptor for Neisseria meningitidis on mononuclear phagocytes in vitro, and the surface proteins NMB0278, NMB0667, and NMB1220 have been identified as ligands for SR-A. …”

Density distribution of pharyngeal carriage of meningococcus in healthy young adults: new approaches to studying the epidemiology of colonization and vaccine indirect effects by Finn, A, Morales-Aza, B, Sikora, P, Giles, J, Lethem, R, Marlais, M, Thors, V, Pollard, A, Faust, S, Heath, P, Vipond, I, Ferreira, M, Muir, P, Januário, L, Rodrigues, F

“…Improved understanding of Neisseria meningitidis (Nm) carriage biology and better methods for detection and quantification would facilitate studies of potential impact of new vaccines on colonization and transmission in adolescents.We performed plate cultures on 107 oropharyngeal swabs stored frozen in STGG broth and previously positive for Nm. …”

Harnessing bioreactivity for protein covalent probes against endogenous targets by Scheu, AHA

“…Harnessing bioreactivity found in covalent pathogen adhesion, in this work I have demonstrated the use of a self activating protein domain from Neisseria meningitidis for covalent reaction against endogenous targets.…”

The molecular epidemiology and ecology of Neisseria species in the African meningitis belt by Diallo, K

“…<p><em>Neisseria meningitidis (Nm)</em> is one of the major causes of bacterial meningitis in the African meningitis belt (AMB). …”

Pathogen- and Type-Specific Changes in Invasive Bacterial Disease Epidemiology during the First Year of the COVID-19 Pandemic in The Netherlands by Anneke Steens, Mirjam J. Knol, Wieke Freudenburg-de Graaf, Hester E. de Melker, Arie van der Ende, Nina M. van Sorge

“…COVID-19 control measures have resulted in a decline in invasive bacterial disease caused by <i>Neisseria meningitidis</i> (IMD), <i>Streptococcus pneumoniae</i> (IPD), and <i>Haemophilus influenzae</i> (Hi-D). …”
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The phosphoethanolamine transferase PetL of Pasteurella multocida is associated with colistin resistance by Jie Yang, Lin Lin, Haixin Bi, Congcong Shi, Qingjie Lv, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng

“…In this study, we found that PetL in P. multocida (PetLPM) exhibited structural characteristics similar to those of the mobile-colistin-resistant (MCR) protein and the PEtn transferase characterized in Neisseria meningitidis. The transformation of petL PM into E. coli or K. pneumoniae changed the phenotype of several tested strains from colistin sensitive to colistin resistant. …”
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The outer membrane protein Omp35 affects the reduction of Fe(III), nitrate, and fumarate by <it>Shewanella oneidensis </it>MR-1 by Myers Charles R, Maier Tamara M

“…Omp35 is related to putative porins from MR-1 and <it>S. frigidimarina </it>as well as to the PorA porin from <it>Neisseria meningitidis</it>. Subcellular fraction analysis confirmed that Omp35 is an OM protein. …”
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Advances in Bacterial Oligosaccharyltransferase Structure Elucidation and Potential Application to Glycoconjugate Vaccine Design by Riye Lu, Pengwei Li, Li Zhu, Ming Xian Chang, Songying Ouyang

“…In particular, the oligosaccharyltransferase (PglB) of Campylobacter jejuni and oligosaccharyltransferase (PglL) enzyme of Neisseria meningitidis are the most characterized OSTs that catalyze bacterial N-linked glycosylation and O-linked glycosylation, respectively. …”
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The Epidemiology of Meningitis among Adults in a South African Province with a High HIV Prevalence, 2009-2012. by Erika Britz, Olga Perovic, Claire von Mollendorf, Anne von Gottberg, Samantha Iyaloo, Vanessa Quan, Verushka Chetty, Charlotte Sriruttan, Nazir A Ismail, Ananta Nanoo, Alfred Musekiwa, Carl Reddy, Karien Viljoen, Cheryl Cohen, Nelesh P Govender

“…Among cases of other bacterial meningitis (248/11,891, 2.1%), Neisseria meningitidis (n = 93), Escherichia coli (n = 72) and Haemophilus influenzae (n = 20) were the most common organisms identified. …”
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Four-year antibody persistence and response to a booster dose of a pentavalent MenABCWY vaccine administered to healthy adolescents and young adults by Xavier Sáez-Llorens, Johnny Beltran-Rodriguez, Jose M. Novoa Pizarro, Ilhem Mensi, Pavitra Keshavan, Daniela Toneatto

“…This open-label, multicenter extension study (NCT02451514) assessed persistence of Neisseria meningitidis serogroups ABCWY antibodies 4 years after primary vaccination. …”
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Accurate, fast and cost-effective simultaneous detection of bacterial meningitis by qualitative PCR with high-resolution melting by Ivano de Filippis, Aline Carvalho de Azevedo, Irene de Oliveira Lima, Nicolle F Lima Ramos, Claudia Ferreira de Andrade, Antonio ECC de Almeida

“…Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are leading causes of meningitis and acute invasive infections. …”
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Invasive meningococcal disease in South-Eastern European countries: Do we need to revise vaccination strategies? by Georgina Tzanakaki, Hana Cabrnochová, Snežana Delić, Anca Draganescu, Anna Hilfanova, Beáta Onozó, Marko Pokorn, Anna Skoczyńska, Goran Tešović

“…ABSTRACTInvasive meningococcal disease (IMD) is an acute life-threatening infection caused by the gram-negative bacterium, Neisseria meningitidis. Globally, there are approximately half a million cases of IMD each year, with incidence varying across geographical regions. …”
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Anti-Virulence Therapeutic Approaches for <i>Neisseria gonorrhoeae</i> by Katherine Y. L. Lim, Christopher A. Mullally, Ethan C. Haese, Emily A. Kibble, Nicolie R. McCluskey, Edward C. Mikucki, Van C. Thai, Keith A. Stubbs, Mitali Sarkar-Tyson, Charlene M. Kahler

“…While antimicrobial resistance (AMR) is seen in both <i>Neisseria gonorrhoeae</i> and <i>Neisseria meningitidis</i>, the former has become resistant to commonly available over-the-counter antibiotic treatments. …”
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Distributed genotyping and clustering of Neisseria strains reveal continual emergence of epidemic meningococcus over a century by Ling Zhong, Menghan Zhang, Libing Sun, Yu Yang, Bo Wang, Haibing Yang, Qiang Shen, Yu Xia, Jiarui Cui, Hui Hang, Yi Ren, Bo Pang, Xiangyu Deng, Yahui Zhan, Heng Li, Zhemin Zhou

“…We classify 69,994 worldwide Neisseria strains into multi-level clusters that assign species, lineages, and local disease outbreaks. We divide Neisseria meningitidis into 168 endemic lineages and three epidemic lineages responsible for at least 9 epidemics in the past century. …”
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TIPICO X: report of the 10th interactive infectious disease workshop on infectious diseases and vaccines by Irene Rivero-Calle, Jose Gómez-Rial, Louis Bont, Bradford D. Gessner, Melvin Kohn, Ron Dagan, Daniel C. Payne, Laia Bruni, Andrew J. Pollard, Adolfo García-Sastre, Denise L. Faustman, Albert Osterhaus, Robb Butler, Francisco Giménez Sánchez, Francisco Álvarez, Myrsini Kaforou, Xabier Bello, Federico Martinón-Torres

“…Cutting-edge advances in vaccination against respiratory syncytial virus, Streptococcus pneumoniae, rotavirus, human papillomavirus, Neisseria meningitidis, influenza virus, and Salmonella Typhi were discussed. …”
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Aetiologies and clinical presentation of central nervous system infections in Vietnamese patients: a prospective study by Julian Justin Gabor, Chu Xuan Anh, Bui Tien Sy, Phan Quoc Hoan, Dao Thanh Quyen, Nguyen Trong The, Salih Kuk, Peter G. Kremsner, Christian G. Meyer, Le Huu Song, Thirumalaisamy P. Velavan

“…The main pathogens causing CNS infections were Streptococcus suis (n = 16; 12%) and Neisseria meningitidis (n = 9; 7%), followed by Herpes simplex virus 1/2 (n = 4; 3%) and Klebsiella pneumoniae (n = 4; 3%). …”
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Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine by Daniel O’Connor, Marta Valente Pinto, Dylan Sheerin, Adriana Tomic, Ruth E Drury, Samuel Channon‐Wells, Ushma Galal, Christina Dold, Hannah Robinson, Simon Kerridge, Emma Plested, Harri Hughes, Lisa Stockdale, Manish Sadarangani, Matthew D Snape, Christine S Rollier, Michael Levin, Andrew J Pollard

“…Abstract Neisseria meningitidis is a major cause of meningitis and septicaemia. …”
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Understanding the Role of Duration of Vaccine Protection with MenAfriVac: Simulating Alternative Vaccination Strategies by Andromachi Karachaliou Prasinou, Andrew J. K. Conlan, Caroline L. Trotter

“…We previously developed a transmission dynamic model of <i>Neisseria meningitidis</i> serogroup A (NmA) with the aim of forecasting the relative benefits of different immunisation strategies with MenAfriVac. …”
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Modular bioengineering of whole-cell catalysis for sialo-oligosaccharide production: coordinated co-expression of CMP-sialic acid synthetase and sialyltransferase by Sabine Schelch, Manuel Eibinger, Jasmin Zuson, Jürgen Kuballa, Bernd Nidetzky

“…Results Difference in enzyme specific activity (CSS from Neisseria meningitidis: 36 U/mg; α2,3-SiaT from Pasteurella dagmatis: 5.7 U/mg) was compensated by differential protein co-expression from tailored plasmid constructs, giving balance between the individual activities at a high level of both (α2,3-SiaT: 9.4 × 102 U/g cell dry mass; CSS: 3.4 × 102 U/g cell dry mass). …”
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Multimodality Imaging Findings in Waterhouse-Friderichsen Syndrome: A Case Report and a Short Literature Review by Maria Luigia Angeli, Annemilia Del Ciello, Claudia Dell’Atti, Federico Orsini, Andrea Piccioni, Laura Franza, Martina Petrucci, Tommaso Pirronti, Francesco Franceschi, Marcello Covino

“…Commonly related to a variety of infectious diseases among which sepsis from <i>Neisseria meningitidis</i> is the most frequent, many other etiologies have been described, and in some rare cases, even no apparent cause can be identified. …”
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