‘Be on the TEAM’ Study (Teenagers Against Meningitis): protocol for a controlled clinical trial evaluating the impact of 4CMenB or MenB-fHbp vaccination on the pharyngeal carriage... by Carr, J, Plested, E, Aley, P, Camara, S, Davis, K, MacLennan, JM, Gray, S, Faust, SN, Borrow, R, Christensen, H, Trotter, C, Maiden, MCJ, Finn, A, Snape, MD

“…<p><strong>Introduction</strong> Capsular group B Neisseria meningitidis (MenB) is the most common cause of invasive meningococcal disease (IMD) in many parts of the world. …”

Persistence of antibody response following a booster dose of Hib-MenC-TT glycoconjugate vaccine to five years: a follow-up study. by Khatami, A, Snape, MD, Wysocki, J, John, T, Westcar, S, Mesaros, N, Peddiraju, K, Boutriau, D, Yu, L, Pollard, A

“… BACKGROUND: Antibodies against Haemophilus influenzae type b (Hib) and serogroup C Neisseria meningitidis (MenC) persist better to 3½ years of age after a 12-month booster dose of a combination Hib-MenC glycoconjugate vaccine (Hib-MenC-TT) in children primed in infancy with Hib-MenC-TT and diphtheria-tetanus-acellular-pertussis-inactivated poliovirus vaccine (DTaP-IPV) than in those who received a monovalent MenC-CRM197 and DTaP-IPV-Hib (also TT conjugated). …”

Multicentre double-blind randomised placebo-controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), against Neisseria gonorrhoeae infection in me... by Eric P F Chow, Christopher K Fairley, Marcus Y Chen, Basil Donovan, Fengyi Jin, Andrew E Grulich, Anna McNulty, Matthew Law, Kate L Seib, Brent Mackie, David A Lewis, Benjamin R Bavinton, David M Whiley, Caroline Thng, Monica M Lahra, Amy V Jennison, Barbara Yeung, Doug Fraser, Michael P Jennings

“…However, there is increasing evidence from observational cohort studies that the serogroup B meningococcal vaccine four-component meningitis B vaccine (4CMenB) (Bexsero), licensed to prevent invasive disease caused by Neisseria meningitidis, may provide cross-protection against the closely related bacterium N. gonorrhoeae. …”
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Decreased Antibiotic Consumption Coincided with Reduction in Bacteremia Caused by Bacterial Species with Respiratory Transmission Potential during the COVID-19 Pandemic by Vincent Chi-Chung Cheng, Shuk-Ching Wong, Simon Yung-Chun So, Jonathan Hon-Kwan Chen, Pui-Hing Chau, Albert Ka-Wing Au, Kelvin Hei-Yeung Chiu, Xin Li, Patrick Ip, Vivien Wai-Man Chuang, David Christopher Lung, Cindy Wing-Sze Tse, Rodney Allan Lee, Kitty Sau-Chun Fung, Wing-Kin To, Raymond Wai-Man Lai, Tak-Lun Que, Janice Yee-Chi Lo, Kwok-Yung Yuen

“…This decrease coincided with a significant reduction in the incidence of community-onset bacteremia due to <i>Streptococcus pyogenes</i>, <i>Streptococcus pneumoniae</i>, <i>Haemophilus influenzae</i>, and <i>Neisseria meningitidis</i>, which are encapsulated bacteria with respiratory transmission potential. …”
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O IMPACTO DA COBERTURA VACINAL CONTRA A MENINGITE MENINGOCÓCICA C SOBRE O NÚMERO DE CASOS DE MENINGITE C NO BRASIL ENTRE 2008 E 2022 by Tifane Alves da Silva, Júlia Hollanda Celestino, Flávia Caminha Rocha, Francisco Augusto da Silva Neto, Diego Oliveira Maia, Timóteo Bezerra Ferreira, Lorena Agra Ramos, Matheus Arraes Marques, Tatiana Paschoalette Rodrigues Bachur

“…Introdução/Objetivo: A meningite infecciosa consiste na inflamação das meninges e do espaço subaracnóide podendo ter etiologia viral ou bacteriana. A Neisseria meningitidis sorotipo C (meningococo C) é o patógeno causador de meningite bacteriana de maior importância para a saúde pública no Brasil pela gravidade do quadro e elevada letalidade. …”
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Características clínicas y paraclínicas de niños con meningitis bacteriana aguda en el Hospital Universitario San Vicente Fundación en Medellín, Colombia. 2011 - 2015: estudio desc... by Julissa Andrea Otero Flórez, María del Pilar Gómez Navas, José William Cornejo Ochoa, Dagoberto Nicanor Cabrera Hemer

“…CONCLUSIÓN: El Streptococcus pneumoniae es el agente causal más frecuente, aunque no se debe descuidar la vigilancia epidemiológica de H. influenzae no tipificable y Neisseria meningitidis. Este estudio nos muestra las dificultades que involucra la identificación de la etiología de la meningitis. …”
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Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Con... by David Shaw, MBBCh, Raquel Abad, PhD, Zahin Amin-Chowdhury, MSc, Adriana Bautista, MSc, Desiree Bennett, PhD, Karen Broughton, MSc, Bin Cao, ProfMD, Carlo Casanova, PhD, Eun Hwa Choi, ProfMD, Yiu-Wai Chu, PhD, Heike Claus, PhD, Juliana Coelho, PhD, Mary Corcoran, PhD, Simon Cottrell, PhD, Robert Cunney, MB, Lize Cuypers, PhD, Tine Dalby, PhD, Heather Davies, NZCS, Linda de Gouveia, NatDipMedTech, Ala-Eddine Deghmane, PhD, Walter Demczuk, BSc, Stefanie Desmet, PhD, Mirian Domenech, PhD, Richard Drew, MD, Mignon du Plessis, PhD, Carolina Duarte, PhD, Helga Erlendsdóttir, ProfMSc, Norman K Fry, PhD, Kurt Fuursted, MD, Thomas Hale, ProfPhD, Desiree Henares, PhD, Birgitta Henriques-Normark, ProfMD, Markus Hilty, PhD, Steen Hoffmann, MD, Hilary Humphreys, ProfMD, Margaret Ip, ProfMSc, Susanne Jacobsson, PhD, Christopher Johnson, PhD, Jillian Johnston, MBBS, Keith A Jolley, PhD, Aníbal Kawabata, Jana Kozakova, MD, Karl G Kristinsson, ProfMD, Pavla Krizova, MD, Alicja Kuch, PhD, Shamez Ladhani, MD, Thiên-Trí Lâm, MD, María Eugenia León, MSc, Laura Lindholm, MSc, David Litt, PhD, Martin C J Maiden, ProfPhD, Irene Martin, BSc, Delphine Martiny, ProfPhD, Wesley Mattheus, PhD, Noel D McCarthy, ProfDPhil, Mary Meehan, PhD, Susan Meiring, MBChB, Paula Mölling, PhD, Eva Morfeldt, PhD, Julie Morgan, HND, Robert Mulhall, PhD, Carmen Muñoz-Almagro, ProfMD, David Murdoch, ProfMD, Joy Murphy, BA Hons, Martin Musilek, PhD, Alexandre Mzabi, MD, Ludmila Novakova, MSc, Shahin Oftadeh, PhD, Amaresh Perez-Argüello, MLT, Maria Pérez-Vázquez, PhD, Monique Perrin, MD, Malorie Perry, MSc, Benoit Prevost, PhD, Maria Roberts, BSc(Hons), Assaf Rokney, PhD, Merav Ron, PhD, Olga Marina Sanabria, MPH, Kevin J Scott, PhD, Carmen Sheppard, PhD, Lotta Siira, PhD, Vitali Sintchenko, ProfPhD, Anna Skoczyńska, ProfPhD, Monica Sloan, Hans-Christian Slotved, DMSc, Andrew J Smith, ProfFRCPath, Anneke Steens, PhD, Muhamed-Kheir Taha, ProfMD, Maija Toropainen, PhD, Georgina Tzanakaki, ProfPhD, Anni Vainio, PhD, Mark P G van der Linden, PhD, Nina M van Sorge, ProfPhD, Emmanuelle Varon, MD, Sandra Vohrnova, MD, Anne von Gottberg, ProfPhD, Jose Yuste, PhD, Rosemeire Zanella, PhD, Fei Zhou, PhD, Angela B Brueggemann, ProfDPhil

“…Summary: Background: The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and Streptococcus agalactiae. We aimed to analyse the incidence and distribution of these diseases during the first 2 years of the COVID-19 pandemic compared to the 2 years preceding the pandemic. …”
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O Custo da Meningite Meningocócica em Portugal by Fernanda Rodrigues, Bernardete Pinheiro, Rita Guerreiro, Miguel Gouveia, João Eloi, Cristina Alves, Guilherme Castela, Alexandra Oliveira, Filipe Palavra, Iolanda Veiros, Margarida Borges

“… Introdução: A doença invasiva meningocócica (DIM) é uma infeção causada pela bactéria Neisseria meningitidis, manifestando-se habitualmente sob a forma de meningite (MM) e/ou septicémia (SM). …”
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Control de un brote epidémico de enfermedad meningocócica por N. meningitidis serogrupo B by María Catalina Pírez, Teresa Picón, Jeannette Galazka, Ivonne Rubio, Alicia Montano, Ana María Ferrari

“… Introducción: en Uruguay, en julio del año 2001, algunos eventos alertaron sobre la posibilidad de un cambio en la evolución de la enfermedad invasiva meningocócica (EIM), por Neisseria meningitidis serogrupo B y señalaron la posibilidad del pasaje de la forma endémica a la forma epidémica de la enfermedad. …”
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Lives saved with vaccination for 10 pathogens across 112 countries in a pre-COVID-19 world by Jaspreet Toor, Susy Echeverria-Londono, Xiang Li, Kaja Abbas, Emily D Carter, Hannah E Clapham, Andrew Clark, Margaret J de Villiers, Kirsten Eilertson, Matthew Ferrari, Ivane Gamkrelidze, Timothy B Hallett, Wes R Hinsley, Daniel Hogan, John H Huber, Michael L Jackson, Kevin Jean, Mark Jit, Andromachi Karachaliou, Petra Klepac, Alicia Kraay, Justin Lessler, Xi Li, Benjamin A Lopman, Tewodaj Mengistu, C Jessica E Metcalf, Sean M Moore, Shevanthi Nayagam, Timos Papadopoulos, T Alex Perkins, Allison Portnoy, Homie Razavi, Devin Razavi-Shearer, Stephen Resch, Colin Sanderson, Steven Sweet, Yvonne Tam, Hira Tanvir, Quan Tran Minh, Caroline L Trotter, Shaun A Truelove, Emilia Vynnycky, Neff Walker, Amy Winter, Kim Woodruff, Neil M Ferguson, Katy AM Gaythorpe

“…We investigate the impact of vaccination activities for Haemophilus influenzae type b, hepatitis B, human papillomavirus, Japanese encephalitis, measles, Neisseria meningitidis serogroup A, rotavirus, rubella, Streptococcus pneumoniae, and yellow fever over the years 2000–2030 across 112 countries. …”
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Resúmenes de Trabajos Libres by Revista CMICA

“…Reporte de caso Catalina Gómez-Parada   Características clínicas y de laboratorio en una cohorte de pacientes con ataxia telangiectasia en el Grupo de Inmunodeficiencias Primarias de la Universidad de Antioquía Lina Rocío Riaño, Jesús Armando Álvarez, Julio César Orrego, Dagoberto Cabrera, Carolina Gómez, Héctor Valderrama, Alexandra Sierra, Derly Carolina Hernández, José Luis Franco   Cuantificación y análisis de citocinas proinflamatorias en pacientes con hallazgos coronariográficos de lesiones ateroscleróticas en la ciudad de Barranquilla, Colombia Franklin Torres, José Villarreal, Marcio de Ávila, Xavier Lastra, Edward Lozano, Martín Oviedo, Axel Tolstano   Estudio de los polimorfismos de los antígenos leucocitarios humanos HLA y citocromos CYP en síndrome de Stevens-Johnson relacionado con fenitoína y carbamazepina en Colombia Nohemí Esther Santodomingo-Guerrero   Estudio de una población barranquillera basada en los alelos DRB1 y DQB1 comparada con otras poblaciones suramericanas Carlos Hernando-Parga   Evaluación de la adsorción de los alérgenos Blo t2 y Blo t3 y del proteoliposoma de Neisseria meningitidis al Al(OH)3 en formulaciones de una vacuna antialérgica adyuvada contra el ácaro Blomia tropicalis Yoskiel Laurencio-Lorca   Exome sequencing reveals gain-of-function mutations in STAT1 conferring predisposition to chronic mucocutaneous candidiasis and tuberculosis in six Colombian patients Marcela Moncada-Vélez, Lucía Victoria Erazo-Borrás, Jesús Armando Álvarez-lvarez, Carlos Andrés Arango, Miyuki Tsumura, Satoshi Okada, Sara Daniela Osorio, Lorena Castro, Natalia González, Catalina Arango, Julio César Orrego, Lina Riaño, Juan Fernando Alzate, Felipe Cabarcas, Jean-Laurent Casanova, Jacinta Bustamante, Anne Puel, Andrés Augusto Arias, José Luis Franco   Experiencia de una clínica de inmunodeficiencias primarias en un centro de atención nivel IV en Cali, Colombia Manuela Olaya-Hernández, Jaime Patiño, Diego Medina, Harry Pachajoa, Viviana Lotero, Paola Pérez   Expression and immunological characterization a heat shock cognate-70 protein allergen, rAed a8, from the mosquito species Aedes aegypti José Fernando Cantillo, Leonardo Puerta, Enrique Fernandez-Caldas, José Luis Subiza, Irene Soria, Sylvie Lafosse-Marin, Barbara Bohle   Gemelos idénticos con enfermedad granulomatosa crónica que se manifestó inicialmente como colitis alérgica. …”
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Quadrivalent meningococcal conjugate vaccines. by Pace, D, Pollard, A, Messonier, N

“…Neisseria meningitidis is an important cause of bacterial meningitis and septicaemia with most disease caused by meningococci bearing serogroups A, B, C, Y and W-135 polysaccharides. …”

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. by Pizza, M, Scarlato, V, Masignani, V, Giuliani, M, Aricò, B, Comanducci, M, Jennings, G, Baldi, L, Bartolini, E, Capecchi, B, Galeotti, C, Luzzi, E, Manetti, R, Marchetti, E, Mora, M, Nuti, S, Ratti, G, Santini, L, Savino, S, Scarselli, M, Storni, E, Zuo, P, Broeker, M, Hundt, E, Knapp, B

“…Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. …”

Meningococcal vaccines. by Collins, C, Pollard, A

“…Neisseria meningitidis is one of the leading infectious causes of death in children under five years old in industrialized countries, and most cases can be attributed to five disease-causing serogroups: A, B, C, Y and W135. …”

Epidemiología de la meningitis Una visión socio-epidemiológica by Arturo Morales Bedoya, Luz Marina Alonso Palacio

“…La meningitis de origen bacteriano, causada principalmente por Neisseriae meningitidis y el Streptococcus pneumoniae, representa la forma más letal de la enfermedad, y tanto su distribución, morbilidad y mortalidad están determinadas por las condiciones económicas y sociales de los países y comunidades más pobres del mundo, en donde la vacunación para su prevención como los medicamentos para su control están muy limitados por el nivel de desarrollo económico.…”
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The epidemiology of meningococcal disease and the impact of vaccines. by Khatami, A, Pollard, A

“…Neisseria meningitidis causes endemic meningococcal disease worldwide. …”

Identification of meningococcal genes necessary for colonization of human upper airway tissue. by Exley, R, Sim, R, Goodwin, L, Winterbotham, M, Schneider, M, Read, R, Tang, C

“…Neisseria meningitidis is an exclusively human pathogen that has evolved primarily to colonize the nasopharynx rather than to cause systemic disease. …”

Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria. by Sadarangani, M, Pollard, A, Gray-Owen, S

“…Neisseria meningitidis and Neisseria gonorrhoeae are globally important pathogens, which in part owe their success to their ability to successfully evade human immune responses over long periods. …”

Potential of recombinant opa proteins as vaccine candidates against hyperinvasive meningococci. by Callaghan, M, Lewis, S, Sadarangani, M, Bailey, SE, Chan, H, Ferguson, D, Derrick, J, Feavers, I, Maiden, M, Pollard, A

“…Neisseria meningitidis causes half a million cases of septicemia and meningitis globally each year. …”

CRM197-conjugated serogroup C meningococcal capsular polysaccharide, but not the native polysaccharide, induces persistent antigen-specific memory B cells. by Kelly, D, Snape, MD, Clutterbuck, E, Cutterbuck, E, Green, S, Snowden, C, Diggle, L, Yu, L, Borkowski, A, Moxon, E, Pollard, A

“…Neisseria meningitidis is one of the leading causes of bacterial meningitis and septicemia in children. …”