Genetic Features of a Representative Panel of 110 Meningococcal B Isolates to Assess the Efficacy of Meningococcal B Vaccines by Alessandro Muzzi, Margherita Bodini, Nadav Topaz, Vega Masignani, Kumaran Vadivelu, Henju Marjuki, Xin Wang, Laura Serino, Duccio Medini

“…ABSTRACT Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates. …”
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Prediction by genetic MATS of 4CMenB vaccine strain coverage of invasive meningococcal serogroup B isolates circulating in Taiwan between 2003 and 2020 by Alessandro Muzzi, Min-Chi Lu, Elena Mori, Alessia Biolchi, Tiffany Fu, Laura Serino

“…ABSTRACT Neisseria meningitidis serogroup B (NmB) strains have diverse antigens, necessitating methods for predicting meningococcal serogroup B (MenB) vaccine strain coverage. …”
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Bacterial Meningitis in the Absence of Cerebrospinal Fluid Pleocytosis: A Case Report and Review of the Literature by Ryota Hase, Naoto Hosokawa, Makito Yaegashi, Kiyoharu Muranaka

“…Here, a case involving an 83-year-old woman who was later diagnosed with bacterial meningitis caused by Neisseria meningitidis is described, in whom CSF at initial and second lumbar puncture did not show elevation of cell counts. …”
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Primary Meningococcal Polyarthritis in an Adult Woman by José Celso Giordan Cavalcanti Sarinho, Marília Soares e Silva Arcadipane, Graziela Tavares Miola Menezes, Danilo Fernando Costa Duarte, Waldenise Cossermelli, Ivan Aprahamian

“…Primary joint infection caused by the Gram-negative bacteria Neisseria meningitidis is rare. Normally, joint involvement comes secondary to meningitis or severe sepsis caused by this agent. …”
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Active Bacterial Core Surveillance of the Emerging Infections Program Network by Anne Schuchat, Tami Hilger, Elizabeth Zell, Monica M. Farley, Arthur L. Reingold, Lee H. Harrison, Lewis Lefkowitz, Richard Danila, Karen Stefonek, Nancy Barrett, Dale Morse, Robert W. Pinner

“…ABCs conducts population-based active surveillance, collects isolates, and performs studies of invasive disease caused by Streptococcus pneumoniae, group A and group B Streptococcus, Neisseria meningitidis, and Haemophilus influenzae for a population of 17 to 30 million. …”
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Meningencefalite por Pasteurella multocida: estudo clínico-laboratorial de um caso em lactente by C. E. Levy, K. Irino, C.R. Funayama, M. Valeriana L. Moura-Ribeiro

“…Ressaltam a importância da P. multocida em casos de meningites bacterianas, fazendo-se o diagnóstico laboratorial diferencial com o Haemophilus influenzae e Neisseria meningitidis em processos infecciosos conseqüentes a arranhadura ou mordida de animais e nas bacteremias ou septicemias em pacientes com hepatopatias crônicas ou em estados de imunodepressão.…”
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Meningococcal W135 Disease Vaccination Intent, the Netherlands, 2018–2019 by Liesbeth Claassen Marion de Vries, Margreet J.M. te Wierik, Feray Coban, Albert Wong, Danielle R.M. Timmermans, Aura Timen

“…To control the rise in Neisseria meningitidis strain W infections, during 2018–2019, the Netherlands launched a catch-up meningococcal conjugate (MenACWY) vaccination campaign for teenagers (13–18 years of age). …”
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Cerebral vein thrombosis due to meningococcal meningitis by Atousa Hakamifard, Helia Hemasian

“…Bacterial meningitis is a life-threatening condition and Neisseria meningitidis is a major cause. Cerebrovascular complications can occur. …”
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Association of a bacteriophage with meningococcal disease in young adults. by Emmanuelle Bille, Roisin Ure, Stephen J Gray, Edward B Kaczmarski, Noel D McCarthy, Xavier Nassif, Martin C J Maiden, Colin R Tinsley

“…Despite being the agent of life-threatening meningitis, Neisseria meningitidis is usually carried asymptomatically in the nasopharynx of humans and only occasionally causes disease. …”
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Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination by Zheng Quan Toh, Rachel A. Higgins, Nadia Mazarakis, Elysia Abbott, Jordan Nathanielsz, Anne Balloch, Kim Mulholland, Paul V. Licciardi

“…Encapsulated bacteria such as <i>Streptococcus pneumoniae</i>, <i>Haemophilus influenzae</i> type b and <i>Neisseria meningitidis</i> cause significant morbidity and mortality in young children despite the availability of vaccines. …”
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Current Meningococcal Vaccines: Advantages and Disadvantages and New Challenges by N. N. Kostyukova, V. A. Bekhalo

“…Among the most important immediate tasks discussed are: the study of the duration and intensity of protection after immunization with conjugate vaccines; the development and subsequent trials of a vaccine against serogroup X; further study and improvement of vaccines against serogroup B, as well as the creation of a single vaccine product that protects against all antigenic variants of Neisseria meningitidis.…”
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Advancements and Challenges in Meningococcal Disease Management and Prevention by Sahira Al-Sanjary, May Al Allaf

“…This research offers detailed insights into managing and preventing meningococcal disease, highlighting Neisseria meningitidis and Neisseria gonorrhoeae as key pathogens. …”
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Disease Susceptibility to ST11 Complex Meningococci Bearing Serogroup C or W135 Polysaccharide Capsules, North America by Andrew J. Pollard, Jan Ochnio, Margaret Ho, Martin Callaghan, Mark Bigham, Simon Dobson

“…Clusters of meningococcal disease caused by a hyperinvasive lineage of Neisseria meningitidis, the ST11 complex, bearing a serogroup C polysaccharide capsule, have been prominent in Europe and North America since the early 1990s. …”
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Recent Application of DNA Microarray Techniques to Diagnose Infectious Disease by Asmare Z, Erkihun M

“…Microarray has various advanced applications in infectious disease diagnostics, including the 2019 pandemic COVID 19, detection of food-borne infectious agents, and detection of Neisseria meningitidis. The aim of this review is to provide updated application of DNA microarray techniques for the diagnosis of infectious diseases and to explore the development of new DNA microarray methods. …”
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Aspectos dos líquidos cefalorraquidianos nas meningites bacterianas by Claudia E. O. Pires de Campos, Nilse N. Q. Santos, Mirian N. Takahashi, Isabel E. Kawamura, Silvia V. Damião, Tuba M. Kushnaroff, Evanil Pires de Campos

“…Foram colhidos 1815 líquidos cefalorraquidianôs de doentes internados com meningite, no Hospital Emílio Ribas, São Paulo, durante os meses de maio a outubro de 1989. Neisseria meningitidis 56%, dos quais 44% do tipo B; Haemophilus influenzae 17%, sendo 72 % isoladas de neonatos até 3 anos; Streptococcus pneumoniae 14%, dos quais 60% isolados de recém nascidos a 1 ano de idade. …”
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The genetic regulation of infant immune responses to vaccination by Melanie eNewport

“…Variants in the genes encoding Toll-like receptors, HLA molecules, cytokines, cytokine receptors have associated with heterogeneity of responses to a wide range of vaccines including measles, hepatitis B, influenza A, BCG, Haemophilus influenzae type b and certain Neisseria meningitidis serotypes, amongst others. However, the vast majority of these studies have been conducted in older children and adults and there are very few data available from studies conducted in infants. …”
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Cerebrospinal Fluid Concentrations of Biogenic Amines: Potential Biomarkers for Diagnosis of Bacterial and Viral Meningitis by Aneela Taj, Nusrat Jamil

“…In these samples, BAs/neurotransmitters i.e., dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5HIAA) were detected and quantified by high performance liquid chromatography with electrochemical detection (HPLC-EC) to determine the neurophysiology of the CNS infections by bacteria (Listeria monocytogenes (Lm) and Neisseria meningitidis (Nm)) and herpes simplex virus (HSV). …”
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BACTERIAL INFECTIOUS DISEASES IN THE COVID-19 ERA by Tatiana C.A. Pinto

“…Invasive infections with respiratory bacterial pathogens, such as Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Bordetella pertussis, Chlamydia pneumoniae and Mycoplasma pneumoniae have had a marked decline in several countries of the world. …”
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Optimal use of meningococcal serogroup B vaccines: moving beyond outbreak control by Paul Balmer, Laura J. York

“…Neisseria meningitidis is a major cause of meningitis and septicemia globally. …”
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Safety and immunogenicity of co-administered meningococcal serogroup B (4CMenB) vaccine: A literature review by Véronique Abitbol, Woo-Yun Sohn, Michael Horn, Marco Aurelio P. Safadi

“…The four-component meningococcal serogroup B vaccine (4CMenB) is indicated for the prevention of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup B. Co-administering 4CMenB with other vaccines may improve vaccine uptake provided that the safety and immunogenicity of either are not affected. …”
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