An Overview of Neisseria meningitidis by Hollingshead, S, Tang, C

“…Neisseria meningitidis (the meningococcus) is a member of the normal nasopharyngeal microbiome in healthy individuals, but can cause septicemia and meningitis in susceptible individuals. …”

Neisseria meningitidis: Methods and protocols by Hollingshead, S, Tang, C, Deghmane, A, Maiden, M

“…Authoritative and practical, Neisseria meningitidis: Methods and Protocols will allow for the use of these methods by more laboratories and foster collaboration and consistency in investigations of this enigmatic and dangerous pathogen.…”

Genealogical typing of Neisseria meningitidis. by Didelot, X, Urwin, R, Maiden, M, Falush, D

“…Here, we propose that different typing schemes should be compared on the basis of their power to infer clonal relationships and investigate the utility of sequence data for genealogical reconstruction by exploiting new statistical tools and data from 20 housekeeping loci for 93 isolates of the bacterial pathogen Neisseria meningitidis. Our analysis demonstrated that all but one of the hyperinvasive isolates established by multilocus enzyme electrophoresis and MLST were grouped into one of six genealogical lineages, each of which contained substantial variation. …”

Applications of nanomaterials in Neisseria meningitidis infection by I. Yañez-Sánchez, B.C. Zamarripa-Pérez, F.J. Gálvez-Gastelum

“…Introduction: Neisseria meningitidis is a bacterium that causes meningitis, a potentially fatal and irreversible disease. …”
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Functional genomics of Neisseria meningitidis pathogenesis. by Sun, Y, Bakshi, S, Chalmers, R, Tang, C

“…The pathogenic bacterium Neisseria meningitidis is an important cause of septicemia and meningitis, especially in childhood. …”

Development of natural immunity to Neisseria meningitidis. by Pollard, A, Frasch, C

“…Although meningococcal disease is rare in industrialized nations, Neisseria meningitidis holds a prominent position amongst pediatric infections because of the dramatic clinical presentation of the disease, high mortality, epidemic potential and the recent disappearance of many other important infectious diseases in developed countries through improvements in public health and vaccination. …”

Correlates of protection against Neisseria Meningitidis. by Pollard, A

“…Over the past two decades, the leading cause of meningitis in childhood and the leading infectious cause of death in the UK has been Neisseria meningitidis. There is now the potential for broad control of this serious disease by vaccination. …”

Investigating host specificity of Neisseria meningitidis by Everett, J, Lea, S, Caesar, J, Johnson, S, Tang, C

Capsular Switching in Invasive Neisseria meningitidis, Brazil by Terezinha M. P. P. Castiñeiras, David E. Barroso, Jane W. Marsh, Mary M. Tulenko, Mary G. Krauland, Maria C. Rebelo, Lee H. Harrison

“…During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B→C capsular switching. …”
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Survival and evasion of Neisseria meningitidis from macrophages by Riya Joshi, Sunil D. Saroj

Subjects: “…Neisseria meningitidis…”
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PorA Variable Regions of Neisseria meningitidis by Joanne E. Russell, Keith A. Jolley, Ian M. Feavers, Martin C. J. Maiden, Janet Suker

Subjects: “…Neisseria meningitidis…”
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Interactions between Neisseria meningitidis and the complement system. by Schneider, M, Exley, R, Ram, S, Sim, R, Tang, C

“…Meningococcal infection remains a worldwide health problem, and understanding the mechanisms by which Neisseria meningitidis evades host innate and acquired immunity is crucial. …”

THE INTERACTION BETWEEN FACTOR H AND NEISSERIA MENINGITIDIS by Tan, L, Schneider, M, Caesar, J, Kugelberg, E, Zhang, Q, Lea, S, Tang, C

Humoral immune responses to Neisseria meningitidis in children. by Pollard, A, Galassini, R, van der Voort, E, Booy, R, Langford, P, Nadel, S, Ison, C, Kroll, J, Poolman, J, Levin, M

“…Serum bactericidal activity was poor in children under 12 months of age despite recent infection with Neisseria meningitidis. The highest levels of bactericidal activity were seen in children over 10 years of age. …”

Temperature triggers immune evasion by Neisseria meningitidis. by Loh, E, Kugelberg, E, Tracy, A, Zhang, Q, Gollan, B, Ewles, H, Chalmers, R, Pelicic, V, Tang, C

“…Neisseria meningitidis has several strategies to evade complement-mediated killing, and these contribute to its ability to cause septicaemic disease and meningitis. …”

Temperature triggers immune evasion by Neisseria meningitidis by Loh, E, Kugelberg, E, Tracy, A, Zhang, Q, Gollan, B, Ewles, H, Chalmers, R, Pelicic, V, Tang, C

“…Neisseria meningitidis has several strategies to evade complement-mediated killing, and these contribute to its ability to cause septicaemic disease and meningitis. …”

Interactions of Neisseria meningitidis with the human immune system by Harding, R

“…<p><em>Neisseria meningitidis</em> is an obligate human pathogen causing over 1000 cases of meningococcal disease within the U.K., 10 % of which result in long-term disability or fatality. 10-70 % of the population carry <em>N. meningitidis</em> in their nasopharynx, the natural reservoir of this bacterium, as a commensal. …”

Multilocus sequence analysis of the pathogen Neisseria meningitidis by Wilson, D

“…<p><em>Neisseria meningitidis</em> is the bacterium responsible for meningococcal meningitis and septicaemia in humans. …”

Description and nomenclature of Neisseria meningitidis capsule locus by Harrison, O, Claus, H, Jiang, Y, Bennett, J, Bratcher, H, Jolley, K, Corton, C, Care, R, Poolman, J, Zollinger, W, Frasch, C, Stephens, D, Feavers, I, Frosch, M, Parkhill, J, Vogel, U, Quail, M, Bentley, S, Maiden, M

“… <p>Pathogenic Neisseria meningitidis isolates contain a polysaccharide capsule that is the main virulence determinant for this bacterium. …”

Sequence conservation of pilus subunits in Neisseria meningitidis. by Cehovin, A, Winterbotham, M, Lucidarme, J, Borrow, R, Tang, C, Exley, R, Pelicic, V

“…The rapid onset and dramatic consequences of Neisseria meningitidis infections make the design of a broadly protective vaccine a priority for public health. …”