NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease by Haakon Berven, Simon Kverneng, Erika Sheard, Mona Søgnen, Solveig Amdahl Af Geijerstam, Kristoffer Haugarvoll, Geir-Olve Skeie, Christian Dölle, Charalampos Tzoulis

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Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus by Fiona Dick, Gard S. Johanson, Charalampos Tzoulis

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Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition by Gonzalo S. Nido, Fiona Dick, Lilah Toker, Kjell Petersen, Guido Alves, Ole-Bjørn Tysnes, Inge Jonassen, Kristoffer Haugarvoll, Charalampos Tzoulis

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Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain by Lilah Toker, Gia T. Tran, Janani Sundaresan, Ole-Bjørn Tysnes, Guido Alves, Kristoffer Haugarvoll, Gonzalo S. Nido, Christian Dölle, Charalampos Tzoulis

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Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease by Johannes J. Gaare, Christian Dölle, Brage Brakedal, Kim Brügger, Kristoffer Haugarvoll, Gonzalo S. Nido, Charalampos Tzoulis

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Early Forms of <i>α</i>-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson’s Disease by Irene Hana Flønes, Harald Nyland, Dagny-Ann Sandnes, Guido Werner Alves, Ole-Bjørn Tysnes, Charalampos Tzoulis

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A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population by Brage Brakedal, Lilah Toker, Kristoffer Haugarvoll, Charalampos Tzoulis

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Brain Tumor Segmentation Based on Minimum Spanning Tree by Simeon Mayala, Ida Herdlevær, Ida Herdlevær, Jonas Bull Haugsøen, Jonas Bull Haugsøen, Shamundeeswari Anandan, Shamundeeswari Anandan, Sonia Gavasso, Sonia Gavasso, Morten Brun

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Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson’s disease by Fiona Dick, Ole-Bjørn Tysnes, Guido W. Alves, Gonzalo S. Nido, Charalampos Tzoulis

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CRMP5 Antibodies—Diagnostic Challenges by Cecilie Totland, Cecilie Totland, Mette Haugen, Mette Haugen, Christian Vedeler, Christian Vedeler, Christian Vedeler

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Neurofilament Light Chain as a Biomarker in Multiple Sclerosis by Kristin N. Varhaug, Kristin N. Varhaug, Kristin N. Varhaug, Øivind Torkildsen, Øivind Torkildsen, Øivind Torkildsen, Kjell-Morten Myhr, Kjell-Morten Myhr, Kjell-Morten Myhr, Christian A. Vedeler, Christian A. Vedeler, Christian A. Vedeler

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Case report: Pain in anti-DPPX encephalitis by Tale L. Bjerknes, Ole Martin Steihaug, Mette Haugen, Ina Elen Hjelland, Christian Alexander Vedeler, Christian Alexander Vedeler

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Disease‐specific phenotypes in iPSC‐derived neural stem cells with POLG mutations by Kristina Xiao Liang, Cecilie Katrin Kristiansen, Sepideh Mostafavi, Guro Helén Vatne, Gina Alien Zantingh, Atefeh Kianian, Charalampos Tzoulis, Lena Elise Høyland, Mathias Ziegler, Roberto Megias Perez, Jessica Furriol, Zhuoyuan Zhang, Novin Balafkan, Yu Hong, Richard Siller, Gareth John Sullivan, Laurence A Bindoff

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Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations by Anbin Chen, Anbin Chen, Anbin Chen, Anbin Chen, Cecilie Katrin Kristiansen, Cecilie Katrin Kristiansen, Yu Hong, Yu Hong, Atefeh Kianian, Evandro Fei Fang, Evandro Fei Fang, Gareth John Sullivan, Gareth John Sullivan, Gareth John Sullivan, Gareth John Sullivan, Jian Wang, Jian Wang, Jian Wang, Xingang Li, Xingang Li, Laurence A. Bindoff, Laurence A. Bindoff, Kristina Xiao Liang, Kristina Xiao Liang

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Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease by Irene H. Flønes, Gerda Ricken, Sigrid Klotz, Alexandra Lang, Thomas Ströbel, Christian Dölle, Gabor G. Kovacs, Charalampos Tzoulis

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Microstructural changes precede depression in patients with relapsing-remitting Multiple Sclerosis by Frank Riemer, Ellen Skorve, Ofer Pasternak, Fulvio Zaccagna, Astri J. Lundervold, Øivind Torkildsen, Kjell-Morten Myhr, Renate Grüner

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Not every estimate counts – evaluation of cell composition estimation approaches in brain bulk tissue data by Lilah Toker, Gonzalo S. Nido, Charalampos Tzoulis

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Serum markers of multiple sclerosis - a new approach by Øivind Torkildsen

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Mitochondrial Respiratory Chain Dysfunction—A Hallmark Pathology of Idiopathic Parkinson’s Disease? by Irene H. Flønes, Irene H. Flønes, Irene H. Flønes, Charalampos Tzoulis, Charalampos Tzoulis, Charalampos Tzoulis

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Editorial: Autoimmunity and the Brain: Paraneoplastic Neurological Injury and Beyond by John E. Greenlee, John E. Greenlee, Noel G. Carlson, Noel G. Carlson, Noel G. Carlson, Justin R. Abbatemarco, Justin R. Abbatemarco, Ida Herdlevær, Stacey L. Clardy, Stacey L. Clardy, Christian A. Vedeler, Christian A. Vedeler

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