Novel Advances in Treatment of Meningiomas: Prognostic and Therapeutic Implications by Gerardo Caruso, Rosamaria Ferrarotto, Antonello Curcio, Luisa Metro, Francesco Pasqualetti, Paola Gaviani, Valeria Barresi, Filippo Flavio Angileri, Maria Caffo

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FUTURE-GB: functional and ultrasound-guided resection of glioblastoma – a two-stage randomised control trial by Plaha, P, Camp, S, Cook, J, McCulloch, P, Voets, N, Ma, R, Taphoorn, MJB, Dirven, L, Grech-Sollars, M, Watts, C, Bulbeck, H, Jenkinson, MD, Williams, M, Lim, A, Dixon, L, Price, SJ, Ashkan, K, Apostolopoulos, V, Barber, VS, Taylor, A, Nandi, D

“…There are multiple other surgical adjuncts available to the neuro-oncology surgeon. However, access to, and usage of these varies widely in UK practice, with limited evidence of their use. …”

Neoadjuvant B-RAF and MEK Inhibitor Targeted Therapy for Adult Papillary Craniopharyngiomas: A New Treatment Paradigm by Francesco Calvanese, Francesco Calvanese, Timothée Jacquesson, Timothée Jacquesson, Timothée Jacquesson, Romain Manet, Alexandre Vasiljevic, Alexandre Vasiljevic, Alexandre Vasiljevic, Alexandre Vasiljevic, Hélène Lasolle, Hélène Lasolle, Hélène Lasolle, Francois Ducray, Francois Ducray, Francois Ducray, Gerald Raverot, Gerald Raverot, Gerald Raverot, Emmanuel Jouanneau, Emmanuel Jouanneau, Emmanuel Jouanneau, Emmanuel Jouanneau

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Cell-Free DNA Extracted from CSF for the Molecular Diagnosis of Pediatric Embryonal Brain Tumors by Mathieu Chicard, Yasmine Iddir, Julien Masliah Planchon, Valérie Combaret, Valéry Attignon, Alexandra Saint-Charles, Didier Frappaz, Cécile Faure-Conter, Kévin Beccaria, Pascale Varlet, Birgit Geoerger, Sylvain Baulande, Gaelle Pierron, Yassine Bouchoucha, François Doz, Olivier Delattre, Joshua J. Waterfall, Franck Bourdeaut, Gudrun Schleiermacher

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Enhanced Malignant Phenotypes of Glioblastoma Cells Surviving NPe6-Mediated Photodynamic Therapy are Regulated via ERK1/2 Activation by Tatsuya Kobayashi, Makoto Miyazaki, Nobuyoshi Sasaki, Shun Yamamuro, Eita Uchida, Daisuke Kawauchi, Masamichi Takahashi, Yohei Otsuka, Kosuke Kumagai, Satoru Takeuchi, Terushige Toyooka, Naoki Otani, Kojiro Wada, Yoshitaka Narita, Hideki Yamaguchi, Yoshihiro Muragaki, Takakazu Kawamata, Kentaro Mori, Koichi Ichimura, Arata Tomiyama

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Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion by Nur P. Damayanti, M. Reza Saadatzadeh, Erika Dobrota, Josue D. Ordaz, Barbara J. Bailey, Pankita H. Pandya, Khadijeh Bijangi-Vishehsaraei, Harlan E. Shannon, Anthony Alfonso, Kathy Coy, Melissa Trowbridge, Anthony L. Sinn, Zhong-Yin Zhang, Rosa I. Gallagher, Julia Wulfkuhle, Emanuel Petricoin, Angela M. Richardson, Mark S. Marshall, Alex Lion, Michael J. Ferguson, Karl E. Balsara, Karen E. Pollok

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Genomic analysis as a tool to infer disparate phylogenetic origins of dysembryoplastic neuroepithelial tumors and their satellite lesions by Yeajina Lee, Jeyul Yang, Seung Ah Choi, Seung‐Ki Kim, Sung-Hye Park, Hyun Joo Park, Jong-Il Kim, Ji Hoon Phi

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Is an Immunosuppressive Microenvironment a Characteristic of Both Intra- and Extraparenchymal Central Nervous Tumors? by Amina Soltani, Bela Kajtar, El Husseiny Mohamed Mahmud Abdelwahab, Anita Steib, Zsolt Horvath, Laszlo Mangel, Luca Jaromi, Judit E. Pongracz

“…Immunotherapy as novel and efficacious treatment option in several other malignancies has failed in neuro-oncology likely due to the immunosuppressive property of the brain tissues. …”
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Is older still good, or even better? Evaluation of possibility of using Miller laryngoscope for intubation in adults and comparison with the most widely used Macintosh laryngoscope... by Paweł Ratajczyk, Krzysztof Wasiak, Przemysław Kluj, Bartosz Szmyd, Caridad G. Castillo-Monzón, Tomasz Gaszyński

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mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in <i>IDH1-</i>Mutated Glioma by Yang Liu, Yanxin Lu, Aiguo Li, Orieta Celiku, Sue Han, Mingyu Qian, Chunzhang Yang

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Suicidality in Patients with Brain Tumors: A Brief Literature Review with Clinical Exemplar by Alessandra Costanza, Francesco Zenga, Roberta Rudà, Andrea Amerio, Andrea Aguglia, Gianluca Serafini, Mario Amore, Guido Bondolfi, Isabella Berardelli, Khoa Dinh Nguyen

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Roles of microRNA-124 in traumatic brain injury: a comprehensive review by Panxing Wu, Bao He, Xiaoliang Li, Xiaoliang Li, Hongwei Zhang

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Tackling the Behavior of Cancer Cells: Molecular Bases for Repurposing Antipsychotic Drugs in the Treatment of Glioblastoma by Michele Persico, Claudia Abbruzzese, Silvia Matteoni, Paola Matarrese, Anna Maria Campana, Veronica Villani, Andrea Pace, Marco G. Paggi

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Recurrent Glioblastoma Treatment: State of the Art and Future Perspectives in the Precision Medicine Era by Augusto Leone, Antonio Colamaria, Nicola Pio Fochi, Matteo Sacco, Matteo Landriscina, Giovanni Parbonetti, Matteo de Notaris, Giulia Coppola, Elena De Santis, Guido Giordano, Francesco Carbone

“…In the present comprehensive review, we sought to examine the current treatment guidelines and the new perspectives that polarize the field of neuro-oncology, strictly focusing on progressive disease. …”
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The G2 checkpoint—a node‐based molecular switch by Mark C. deGooijer, Arnout van denTop, Irena Bockaj, Jos H. Beijnen, Thomas Würdinger, Olaf vanTellingen

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Diagnosis and Treatment of Peripheral and Cranial Nerve Tumors with Expert Recommendations: An EUropean Network for RAre CANcers (EURACAN) Initiative by Alessia Pellerino, Robert M. Verdijk, Lucia Nichelli, Nicolaus H. Andratschke, Ahmed Idbaih, Roland Goldbrunner

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Prognostic and Predictive Biomarkers in Gliomas by Paulina Śledzińska, Marek G. Bebyn, Jacek Furtak, Janusz Kowalewski, Marzena A. Lewandowska

“…Given the rapid progress in neuro-oncology, here we compile the latest research on prognostic and predictive biomarkers in gliomas. …”
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Tracking Therapy Response in Glioblastoma Using 1D Convolutional Neural Networks by Sandra Ortega-Martorell, Ivan Olier, Orlando Hernandez, Paula D. Restrepo-Galvis, Ryan A. A. Bellfield, Ana Paula Candiota

“…Evaluating therapy response relies on magnetic resonance imaging (MRI) following the Response Assessment in Neuro-Oncology (RANO) criteria. However, early assessment is hindered by phenomena such as pseudoprogression and pseudoresponse. …”
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Mechanisms of NLRP3 inflammasome-mediated hepatic stellate cell activation: Therapeutic potential for liver fibrosis by Harsh Vardhan Charan, Durgesh Kumar Dwivedi, Sabbir Khan, Gopabandhu Jena

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Brentuximab-Induced Peripheral Neurotoxicity: A Multidisciplinary Approach to Manage an Emerging Challenge in Hodgkin Lymphoma Therapy by Roser Velasco, Eva Domingo-Domenech, Anna Sureda

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