INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas by Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas, Dietmar Krex, Peter Vajkoczy, Antje Wick, Inga Harting, Felix Sahm, Andreas von Deimling, Martin Bendszus, Wolfgang Wick, Michael Platten

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Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment by Maria D. Chirlaque, Rafael Peris-Bonet, Antonia Sánchez, Ofelia Cruz, Rafael Marcos-Gragera, Gonzalo Gutiérrez-Ávila, José R. Quirós-García, Fernando Almela-Vich, Arantza López de Munain, Maria J. Sánchez, Paula Franch-Sureda, Eva Ardanaz, Jaume Galceran, Carmen Martos, Diego Salmerón, Gemma Gatta, Laura Botta, Adela Cañete, the Spanish Childhood Cancer Epidemiology Working Group

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Research on application of tumor treating fields in glioblastoma: A bibliometric and visual analysis by Xue Du, Xue Du, Chunbao Chen, Yu Xiao, Yu Cui, Yu Cui, Lu Yang, Lu Yang, Xiaochun Li, Xiaochun Li, Xueping Liu, Xueping Liu, Ruisi Wang, Ruisi Wang, Bangxian Tan, Bangxian Tan

“…STUPP R (236) was the most cited author followed by KIRSON ED (164) and GILADI M (104). JOURNAL OF NEURO-ONCOLOGY (22) was the journal with the largest number of published publications (75), followed by FRONTIERS IN ONCOLOGY (15) and CANCERS (13). …”
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ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion by Barbara Bassani, Giorgia Simonetti, Valeria Cancila, Antonio Fiorino, Marilena Ciciarello, Annamaria Piva, Arman Mandegar Khorasani, Claudia Chiodoni, Daniele Lecis, Alessandro Gulino, Eugenio Fonzi, Laura Botti, Paola Portararo, Massimo Costanza, Marta Brambilla, Giorgia Colombo, Juerg Schwaller, Alexandar Tzankov, Maurilio Ponzoni, Fabio Ciceri, Niccolò Bolli, Antonio Curti, Claudio Tripodo, Mario P. Colombo, Sabina Sangaletti

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Case Report: Initial Treatment Adjustments and Complications in Ovarian Cancer Patient With Inborn Error of Immunity by Jamila Mammadova, Anna Redden, Rachel Cruz, Boglarka Ujhazi, Sumai Gordon, Maryssa Ellison, Tyra Gatewood, Carla Duff, Anthony Cannella, Charurut Somboonwit, Chakrapol Sriaroon, Krisztian Csomos, Joseph F. Dasso, Terry Harville, Roohi Ismail-Khan, Jolan E. Walter

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Radiosurgery and Stereotactic Brain Radiotherapy with Systemic Therapy in Recurrent High-Grade Gliomas: Is It Feasible? Therapeutic Strategies in Recurrent High-Grade Gliomas by Fabiana Gregucci, Alessia Surgo, Roberta Carbonara, Letizia Laera, Maria Paola Ciliberti, Maria Annunziata Gentile, Morena Caliandro, Nicola Sasso, Ilaria Bonaparte, Vincenzo Fanelli, Romina Tortora, Eleonora Paulicelli, Giammarco Surico, Giuseppe Lombardi, Francesco Signorelli, Alba Fiorentino

“…Material/Methods: All patients with histological diagnosis of HGG that suffered by recurrent disease diagnosed by magnetic resonance imaging (MRI), according to Response Assessment in Neuro-Oncology (RANO) criteria, after primary/adjuvant chemo-radiotherapy treatment and underwent to re-RT by SRS/FSRT were included in the analysis. …”
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Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric asses... by Kenji Yoshida, Tomoyuki Akita, Kosuke Katayama, Kiyohide Kakuta, Takafumi Nishizaki, Fumiyuki Yamasaki, Hirotaka Fudaba, Kenichiro Asano, Takashi Sasayama, Manabu Natsumeda, Taichi Shimabukuro, Kotaro Taguchi, Shinichiro Koizumi, Noriyuki Nakayama, Kentaro Fujii, Ikuno Nishibuchi, Kazuhiko Sugiyama, Ushio Yonezawa, Momii Yasutomo, Yukari Kawasaki, Kazuhiro Tanaka, Hiroaki Nagashima, Yoshihiro Tsukamoto, Makoto Ideguchi, Kazuhiko Kurozumi, Tomohiro Hosoya, Atsushi Kambe

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Insights into Healthcare Professionals’ Perceptions and Attitudes toward Nanotechnological Device Application: What Is the Current Situation in Glioblastoma Research? by Federica Ragucci, Francesca Sireci, Francesco Cavallieri, Jessica Rossi, Giuseppe Biagini, Giovanni Tosi, Chiara Lucchi, Rodolfo Molina-Pena, Natalia Helen Ferreira, Mariana Zarur, Alba Ferreiros, William Bourgeois, François Berger, Miguel Abal, Audrey Rousseau, Frank Boury, Carmen Alvarez-Lorenzo, Emmanuel Garcion, Anna Pisanello, Giacomo Pavesi, Corrado Iaccarino, Luca Ghirotto, Maria Chiara Bassi, Franco Valzania

“…To date, most scientific studies on nanomaterial development have focused on deepening the attitudes of end users and experts, leaving clinical practice implications unexplored. Neuro-oncology might be a promising field for the application of nanotechnologies, especially for malignant brain tumors with a low-survival rate such as glioblastoma (GBM). …”
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Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, op... by Jing Li, Yan Wang, Chad Tang, James Welsh, Renata Ferrarotto, Mehmet Altan, Tina Cascone, Juhee Song, Marcelo V Negrao, John V Heymach, Brett W Carter, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Caroline Chung, George R Blumenschein, Nandita Guha-Thakurta, Jeffrey S Wefel, Amol J Ghia, Debra N Yeboa, Mary Frances McAleer, Kristina D Woodhouse, Susan L McGovern, Chenyang Wang, Betty Y S Kim, Jeffrey S Weinberg, Tina M Briere

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Robotic stereotactic radiosurgery for intracranial meningiomas in elderly patients: assessment of treatment efficacy and safety by Anton Früh, Anton Früh, Bohdan Bodnar, Marcel Nachbar, Julia Gradhand, Julia Gradhand, Goda Kalinauskaite, Kerstin Rubarth, Kerstin Rubarth, Peter Truckenmueller, David Kaul, Daniel Zips, Peter Vajkoczy, Carolin Senger, Güliz Acker, Güliz Acker, Güliz Acker

“…Tumor response was evaluated using the Response Assessment in Neuro-Oncology (RANO) criteria for meningiomas. Adverse effects were graded using the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 and a cox regression was performed to investigate possible predictors.ResultsWe identified 82 patients with 102 CK-treated lesions that matched the criteria for the first SRS. …”
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Anlotinib as Monotherapy or Combination Therapy for Recurrent High-Grade Glioma: A Retrospective Study by Jun Yin, Wenya Yin, Linlin Zheng, Yimin Li, Cheng Luo, Shuo Zhang, Lei Duan, Hang Zhou, Kai Cheng, Jinyi Lang, Ke Xu

“…Evaluation of treatment response was performed according to RANO (response assessment in neuro-oncology, RANO) criteria, including 21 partial response, 6 stable disease, and 2 PFS events. …”
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A Prospective, Cohort Study of SITOIGANAP to Treat Glioblastoma When Given in Combination With Granulocyte-Macrophage Colony-Stimulating Factor/Cyclophosphamide/Bevacizumab/Nivolum... by Daniela A. Bota, Daniela A. Bota, Daniela A. Bota, Thomas H. Taylor, Thomas H. Taylor, Naomi Lomeli, Xiao-Tang Kong, Xiao-Tang Kong, Xiao-Tang Kong, Beverly D. Fu, Beverly D. Fu, Axel H. Schönthal, Samuel Singer, Deborah T. Blumenthal, Frank M. Senecal, Helena Linardou, Evangelos Rokas, Dimitris G. Antoniou, Virgil E. J. C. Schijns, Thomas C. Chen, Thomas C. Chen, Thomas C. Chen, Joseph Elliot, Apostolos Stathopoulos, Apostolos Stathopoulos, Apostolos Stathopoulos, Apostolos Stathopoulos

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Gal-1 Expression Analysis in the GLIOCAT Multicenter Study: Role as a Prognostic Factor and an Immune-Suppressive Biomarker by Neus Martínez-Bosch, Noelia Vilariño, Francesc Alameda, Sergi Mojal, Montserrat Arumí-Uria, Cristina Carrato, Iban Aldecoa, Teresa Ribalta, Noemí Vidal, Beatriz Bellosillo, Silvia Menéndez, Sonia Del Barco, Oscar Gallego, Estela Pineda, Raquel López-Martos, Ainhoa Hernández, Carlos Mesia, Anna Esteve-Codina, Nuria de la Iglesia, Carme Balañá, María Martínez-García, Pilar Navarro

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Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer by Matías Garcia Fallit, Matías L. Pidre, Antonela S. Asad, Jorge A. Peña Agudelo, Mariana B. Vera, Alejandro J. Nicola Candia, Sofia B. Sagripanti, Melanie Pérez Kuper, Leslie C. Amorós Morales, Abril Marchesini, Nazareno Gonzalez, Carla M. Caruso, Víctor Romanowski, Adriana Seilicovich, Guillermo A. Videla-Richardson, Flavia A. Zanetti, Marianela Candolfi

“…We compared them with adenoviral vectors (AdV), which are used in neuro-oncology, but for which there is pre-existing immunity. …”
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361 WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma by Christopher Hubert, Kelly Mitchell, Samuel Sprowls, Sajina Shakya, Sonali Arora, Daniel J. Silver, Christopher M. Goins, Lisa Wallace, Gustavo Roversi, Rachel Schafer, Kristen Kay, Tyler E. Miller, Adam Lauko, John Bassett, Anjali Kashyap, J. D’Amato Kass, Erin E. Mulkearns-Hubert, Sadie Johnson, Joseph Alvarado, Jeremy N. Rich, Patrick J. Paddison, Anoop P. Patel, Shaun R. Stauffer, Christopher G. Hubert, Justin D. Lathia

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Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation by Eric A. Stahlberg, Mohamed Abdel-Rahman, Boris Aguilar, Alireza Asadpoure, Robert A. Beckman, Lynn L. Borkon, Jeffrey N. Bryan, Colleen M. Cebulla, Young Hwan Chang, Ansu Chatterjee, Jun Deng, Sepideh Dolatshahi, Olivier Gevaert, Emily J. Greenspan, Wenrui Hao, Tina Hernandez-Boussard, Pamela R. Jackson, Marieke Kuijjer, Adrian Lee, Paul Macklin, Subha Madhavan, Matthew D. McCoy, Navid Mohammad Mirzaei, Talayeh Razzaghi, Heber L. Rocha, Leili Shahriyari, Ilya Shmulevich, Daniel G. Stover, Yi Sun, Tanveer Syeda-Mahmood, Jinhua Wang, Qi Wang, Ioannis Zervantonakis

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Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma‐related epilepsy by Shuli Liang, Xing Fan, Ming Zhao, Xia Shan, Wenling Li, Ping Ding, Gan You, Zhen Hong, Xuejun Yang, Guoming Luan, Wenbin Ma, Hui Yang, Yongpin You, Tianming Yang, Liang Li, Weiping Liao, Lei Wang, Xun Wu, Xinguang Yu, Jianguo Zhang, Qing Mao, Yuping Wang, Wenbin Li, Xuefeng Wang, Chuanlu Jiang, Xiaoyan Liu, Songtao Qi, Xingzhou Liu, Yan Qu, Jiwen Xu, Weimin Wang, Zhi Song, Jinsong Wu, Zhixiong Liu, Ling Chen, Yuanxiang Lin, Jian Zhou, Xianzeng Liu, Wei Zhang, Shichuo Li, Tao Jiang

“…Methods In March 2017, the Joint Task Force for GRE of China Association Against Epilepsy and Society for Neuro‐Oncology of China launched the guideline committee for the diagnosis and treatment of GRE. …”
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[18F]-fluoroethyl-L-tyrosine (FET) in glioblastoma (FIG) TROG 18.06 study: protocol for a prospective, multicentre PET/CT trial by Eng-Siew Koh, Mustafa Khasraw, Elizabeth H Barnes, Kyle M Walsh, Mark Rosenthal, Rodney J Hicks, Farshad Foroudi, Hui K Gan, Anna K Nowak, Dale L Bailey, Paul Roach, Arian Lasocki, Robyn Leonard, Roel Verhaak, Andrew M Scott, Alisha Moore, Bradford A Moffat, Clare Senko, Roslyn J Francis, Martin Ebert, Sze Ting Lee, Eddie Lau, Greg Fitt, Robert Coffey, Richard De Abreu Lourenco, Lucas Adda, Paul A Thomas, Michael Back

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Replicative Instability Drives Cancer Progression by Benjamin B. Morris, Jason P. Smith, Qi Zhang, Zhijie Jiang, Oliver A. Hampton, Michelle L. Churchman, Susanne M. Arnold, Dwight H. Owen, Jhanelle E. Gray, Patrick M. Dillon, Hatem H. Soliman, Daniel G. Stover, Howard Colman, Arnab Chakravarti, Kenneth H. Shain, Ariosto S. Silva, John L. Villano, Michael A. Vogelbaum, Virginia F. Borges, Wallace L. Akerley, Ryan D. Gentzler, Richard D. Hall, Cindy B. Matsen, C. M. Ulrich, Andrew R. Post, David A. Nix, Eric A. Singer, James M. Larner, Peter Todd Stukenberg, David R. Jones, Marty W. Mayo

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Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation by Mutsuko Minata, Alessandra Audia, Junfeng Shi, Songjian Lu, Joshua Bernstock, Marat S. Pavlyukov, Arvid Das, Sung-Hak Kim, Yong Jae Shin, Yeri Lee, Harim Koo, Kirti Snigdha, Indrayani Waghmare, Xing Guo, Ahmed Mohyeldin, Daniel Gallego-Perez, Jia Wang, Dongquan Chen, Peng Cheng, Farah Mukheef, Minerva Contreras, Joel F. Reyes, Brian Vaillant, Erik P. Sulman, Shi-Yuan Cheng, James M. Markert, Bakhos A. Tannous, Xinghua Lu, Madhuri Kango-Singh, L. James Lee, Do-Hyun Nam, Ichiro Nakano, Krishna P. Bhat

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