Anti-PD-1 immune-related adverse events are associated with high therapeutic antibody fixation on T cells by Marianne Gazzano, Christophe Parizot, Dimitri Psimaras, Aurore Vozy, Marine Baron, Baptiste Abbar, Vincent Fallet, Elena Litvinova, Anthony Canellas, Cristina Birzu, Cristina Birzu, Valérie Pourcher, Valérie Pourcher, Mehdi Touat, Mehdi Touat, Nicolas Weiss, Sophie Demeret, Damien Roos-Weil, Jean-Philippe Spano, Celeste Lebbe, Joe-Elie Salem, Jacques Cadranel, Baptiste Hervier, Guy Gorochov, Amélie Guihot, Amélie Guihot

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Combination of RUNX1 inhibitor and gemcitabine mitigates chemo‐resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stres... by Chunhua She, Chao Wu, Weihua Guo, Yongjie Xie, Shouyi Li, Weishuai Liu, Chao Xu, Hui Li, Pei Cao, Yanfang Yang, Xiuchao Wang, Antao Chang, Yukuan Feng, Jihui Hao

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Spatial and Ecological Factors Modulate the Incidence of Anti-NMDAR Encephalitis—A Systematic Review by Agustí Alentorn, Giulia Berzero, Harry Alexopoulos, John Tzartos, Germán Reyes Botero, Andrea Morales Martínez, Sergio Muñiz-Castrillo, Alberto Vogrig, Bastien Joubert, Francisco A. García Jiménez, Dagoberto Cabrera, José Vladimir Tobon, Carolina Delgado, Patricio Sandoval, Mónica Troncoso, Lorna Galleguillos, Marine Giry, Marion Benazra, Isaias Hernández Verdin, Maëlle Dade, Géraldine Picard, Véronique Rogemond, Nicolas Weiss, Marinos C. Dalakas, Pierre-Yves Boëlle, Jean-Yves Delattre, Jérôme Honnorat, Dimitri Psimaras

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Prognostic and Predictive Value of Integrated Qualitative and Quantitative Magnetic Resonance Imaging Analysis in Glioblastoma by Maikel Verduin, Sergey Primakov, Inge Compter, Henry C. Woodruff, Sander M. J. van Kuijk, Bram L. T. Ramaekers, Maarten te Dorsthorst, Elles G. M. Revenich, Mark ter Laan, Sjoert A. H. Pegge, Frederick J. A. Meijer, Jan Beckervordersandforth, Ernst Jan Speel, Benno Kusters, Wendy W. J. de Leng, Monique M. Anten, Martijn P. G. Broen, Linda Ackermans, Olaf E. M. G. Schijns, Onno Teernstra, Koos Hovinga, Marc A. Vooijs, Vivianne C. G. Tjan-Heijnen, Danielle B. P. Eekers, Alida A. Postma, Philippe Lambin, Ann Hoeben

“…A retrospective analysis of GBM patients in two neuro-oncology centers was conducted. The multimodal Cox-regression model to predict overall survival (OS) was developed using clinical features with VASARI and radiomics features in isocitrate dehydrogenase (<i>IDH</i>)-wild type GBM. …”
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A novel HIF2A mutation causes dyslipidemia and promotes hepatic lipid accumulation by Feiqiong Gao, Qigu Yao, Jiaqi Zhu, Wenyi Chen, Xudong Feng, Bing Feng, Jian Wu, Karel Pacak, Jared Rosenblum, Jiong Yu, Zhengping Zhuang, Hongcui Cao, Lanjuan Li

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IFITM3 promotes glioblastoma stem cell-mediated angiogenesis via regulating JAK/STAT3/bFGF signaling pathway by Zhangsheng Xiong, Xiangdong Xu, Yuxuan Zhang, Chengcheng Ma, Chongxian Hou, Zhongsheng You, Lingling Shu, Yiquan Ke, Yang Liu

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Impact of remoteness and rurality on the treatment and survival of patients with glioblastoma in the north of Scotland by Damjan Veljanoski, Raphae Barlas, Aimun A.B. Jamjoom, James Walkden, Graham Horgan, Rafael Moleron, Phyo Kyaw Myint, Anastasios Giamouriadis

“…Median driving time to the neuro-oncological centre was 36 min and to the GP this was 6 min. …”
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Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma by Yang Liu, Xiangdong Xu, Yuxuan Zhang, Yunzhao Mo, Xinlin Sun, Lingling Shu, Yiquan Ke

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Processing Speed and Time since Diagnosis Predict Adaptive Functioning Measured with WeeFIM in Pediatric Brain Tumor Survivors by Maria Chiara Oprandi, Viola Oldrati, Morena delle Fave, Daniele Panzeri, Lorenza Gandola, Maura Massimino, Alessandra Bardoni, Geraldina Poggi

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Sociocognitive Functioning and Psychosocial Burden in Patients with Brain Tumors by Milena Pertz, Uwe Schlegel, Patrizia Thoma

“…Brain tumors may represent devastating diseases and neuro-oncological research in the past solely focused on development of better treatments to achieve disease control. …”
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The Influence of Socioeconomic Status (SES) and Processing Speed on the Psychological Adjustment and Wellbeing of Pediatric Brain Tumor Survivors by Maria Chiara Oprandi, Viola Oldrati, Claudia Cavatorta, Lorenza Gandola, Maura Massimino, Alessandra Bardoni, Geraldina Poggi

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Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation and Reductive Carboxylation in Cancer and Their Clinical Significance by Qiwei He, Junxiong Chen, Zijing Xie, Zhenzhou Chen

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Central nervous system tumors in children: trends of the past decade by Kh. M. Vakhitov, A. R. Volkova, R. Z. Shammasov, E. I. Nizamutdinova, E. V. Kumirova, I. V. Osipova

“…The article presents the current state of the domestic children’s neuro-oncological system; also it highlights the main development trends over the past decade. …”
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Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma by Magda Sayed Mahmoud, Mohamed K. Khalifa, Amira M. Nageeb, Lobna R. Ezz El-Arab, Manal El-Mahdy, Amal Ramadan, Maha Hashim, Noha M. Bakr, Menha Swellam

“…It was aimed to investigate the clinical role of IDH1 mutation and MGMT methylation pattern among GBM patients versus non-neuro-oncological diseases (NND) patients and their impact on survival criteria. …”
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Impact of dedicated neuro-anesthesia management on clinical outcomes in glioblastoma patients: A single-institution cohort study by Jasper Kees Wim Gerritsen, Dimitris Rizopoulos, Joost Willem Schouten, Iain Kristian Haitsma, Ismail Eralp, Markus Klimek, Clemens Maria Franciscus Dirven, Arnaud Jean Pierre Edouard Vincent

“…We also investigated the value of dedicated neuro-oncological surgical teams as an independent variable in both groups. …”
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The Long and Winding Road: An Overview of the Immunological Landscape of Intracranial Meningiomas by Giuseppe Roberto Giammalva, Lara Brunasso, Federica Paolini, Roberta Costanzo, Lapo Bonosi, Umberto Emanuele Benigno, Gianluca Ferini, Serena Sava, Cristina Colarossi, Giuseppe Emmanuele Umana, Rosa Maria Gerardi, Carmelo Lucio Sturiale, Alessio Albanese, Domenico Gerardo Iacopino, Rosario Maugeri

“…The role of immunotherapy is gaining ever-increasing interest in the neuro-oncological field, and this is also expanding to the management of intracranial meningioma. …”
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Multicentric Glioma: An Ideal Model to Reveal the Mechanism of Glioma by Yong Yan, Wei Dai, Qiyong Mei

“…According to the stem-cell-origin theory, multiple lesions of multicentric glioma share the same neuro-oncological origin, both in gene level and in cell level. …”
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The AANS Harvey Cushing Medal: a demographic and academic analysis of its recipients by Kevin Pierre, Olgert Bardhi, Dimitri Laurent, Sasha Vaziri, Brandon Lucke-Wold, Meghan M. Brennan, Abeer Dagra, Bankole Olowofela, Ernest Barthélemy

“…Results Predominantly, recipients graduated from top-ranked United States News and World Report institutions and specialized in cerebrovascular and neuro-oncologic/skull base neurosurgery. A significant proportion held roles as department or division chairs and led neurosurgical organizations. …”
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Moving towards a unified classification of glioblastomas utilizing artificial intelligence and deep machine learning integration by Ciaran Scott Hill, Ciaran Scott Hill, Anand S. Pandit, Anand S. Pandit

“…In doing so there is the potential to generate clinically relevant disease sub-stratifications, which could help predict neuro-oncological patient outcomes with greater certainty. …”
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Identification of Cerebrospinal Fluid MicroRNAs Associated With Leptomeningeal Metastasis From Lung Adenocarcinoma by Zhenyu Pan, Zhenyu Pan, Zhenyu Pan, Guozi Yang, Guozi Yang, Hua He, Pengxiang Gao, Tongchao Jiang, Yong Chen, Gang Zhao

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