Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs by Hassan, Zurina, Oliver G., Bosch, Singh, Darshan, Narayanan, Suresh, Kasinather, B. Vicknasingam, Erich, Seifritz, Johannes, Kornhuber, Boris B. , Quednow, Christian P. , Müller

“…Here, we provide a summary review on a number of NPS for which the neuropharmacological evaluation has made important progress in recent years. …”
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Natural product-based nanomedicine: recent advances and issues for the treatment of Alzheimer's disease by Choy, Ker Woon, Wong, Kah Hui, Abas, Razif, Haron, Muhammad Huzaimi, Das, Srijit, Teoh Seong, Lin

In Vitro blood-brain barrier models for neuroinfectious diseases: a narrative review by Badawi, Ahmad Hussein, Mohamad, Nur Afiqah, Stanslas, Johnson, Kirby, Brian Patrick, Neela, Vasantha Kumari, Ramasamy, Rajesh, Basri, Hamidon

A preliminary nuclear magnetic resonance metabolomics study identifies metabolites that could serve as diagnostic markers of major depressive disorder by Mohammed Badamasi, Ibrahim, Maulidiani, Maulidiani, Munn, Sann Lye, Ibrahim, Normala, Shaari, Khozirah, Stanslas, Johnson

Zebrafish (Danio rerio) vs. Javanese medaka (Oryzias javanicus), who is more anxious? by Wan Ibrahim, Wan Norhamidah, Ali, Madihah, Mohd Sataa, Nor Syafida, Abu Bakar, Noraini, Ramlan, Nurul Farhana

“…These two situations increased the use of animal models for toxicological and neuropharmacological studies. In this context, a Malaysian native fish species, Javanese medaka (Oryzias javanicus) offer an opportunity to be developed as a model organism for neurotoxicology and neuropharmacology study. …”
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Peranan dan pengaturan ketergantungan psikis opioid oleh tipe reseptor opioid by Perpustakaan UGM, i-lib

“…The development of selective receptor agonist and cloning of each receptor have contributed greatly to our increasing knowledge of the neuropharmacological profile of each opioid receptor type. …”

Thymoquinone prevents β-amyloid neurotoxicity in primary cultured cerebellar granule neurons by Ismail, Norsharina, Ismail, Maznah, Mazlan, Musalmah, Abd Latiff, Latiffah, Imam, Mustapha Umar, Iqbal, Shahid, Azmi, Nur Hanisah, Abd Ghafar, Siti Aisyah, Kim, Wei Chan

“…Thymoquinone (TQ), a bioactive constituent of Nigella sativa Linn (N. sativa) has demonstrated several neuropharmacological attributes. In the present study, the neuroprotective properties of TQ were investigated by studying its anti-apoptotic potential to diminish β-amyloid peptide 1–40 sequence (Aβ1–40)-induced neuronal cell death in primary cultured cerebellar granule neurons (CGNs). …”
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Piper species: a comprehensive review on their phytochemistry, biological activities and applications by Salehi, Bahare, Zakaria, Zainul Amiruddin, Gyawali, Rabin, Ibrahim, Salam A., Rajkovic, Jovana, Shinwari, Zabta Khan, Khan, Tariq, Sharifi-Rad, Javad, Ozleyen, Adem, Turkdonmez, Elif, Valussi, Marco, Tumer, Tugba Boyunegmez, Fidalgo, Lianet Monzote, Martorell, Miquel, Setzer, William N.

“…Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro and in vivo studies, besides clinical studies. …”
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Antidepressant-like effect of aqueous extract of Channa striatus fillet in mice models of depression. by Saleem, A. M., Baharuldin, Mohamad Taufik Hidayat, Mat Jais, Abdul Manan, Fakurazi, Sharida, Mohd Moklas, Mohamad Aris, Sulaiman, Mohd Roslan, Amom, Zulkhairi

“…There is no scientific report on neuropharmacological effects of C. striatus. Based on these data, the antidepressant-like effect of C. striatus was evaluated in mice models of depression. …”
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Mitragynine (Kratom) impairs spatial learning and hippocampal synaptic transmission in rats by Hassan, Zurina, Suhaimi, Farah W., Ramanathan, Surash, Ling, King Hwa, Effendy, Mohamad A., Muller, Christian P., Dringenberg, Hans C.

“…While addictive effects of the substance are emerging, adverse cognitive effects of this drug and neuropharmacological actions are insufficiently understood. …”
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Pleurotus giganteus (Berk.) Karunarathna & K.D. Hyde: nutritional value and in vitro neurite outgrowth activity in rat pheochromocytoma cells by Phan, C.W., Wong, W.L., David, P., Naidu, M., Sabaratnam, V.

“…Medicinal mushrooms which harness neuropharmacological compounds offer a potential possibility for protection against such diseases. …”
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Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in resp... by Ismail, Norsharina, Ismail, Maznah, Azmi, Nur Hanisah, Bakar, Muhammad Firdaus Abu, Yida, Zhang, Abdullah, Maizaton Atmadini, Basri, Hamidon

“…Studies suggest that high cholesterol and a high fat diet have harmful effects on cognitive function and may instigate the commencement of AD pathogenesis. Despite the neuropharmacological attributes of black cumin seed (Nigella sativa) extracts and its main active compound, thymoquinone (TQ), limited records are available in relation to AD research. …”
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Characterization of antiepileptic and anxiolytic activities of ethyl acetate fraction from Swietenia macrophylla king seeds by Mustak, Sayyad

“…The main objective of this study was to characterize the potential neuropharmacological activity of ethyl acetate fraction of Swietenia macrophylla seeds (SMEAF) in experimental animal models. …”
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Neuroprotective effects of thymoquinone-rich fraction and thymoquinone nanoemulsions in sporadic alzheimer’s disease rat model by Ismail, Norsharina

“…Despite of the neuropharmacological attributes of Nigella sativa (black cumin seeds) and its active constituent, thymoquinone (TQ), limited records are available in relation to AD researches. …”
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