Investigating female versus male differences in white matter neuroplasticity associated with complex visuo-motor learning by Eric D. Kirby, Justin W. Andrushko, Shie Rinat, Ryan C. N. D’Arcy, Lara A. Boyd

“…Abstract Magnetic resonance imaging (MRI) has increasingly been used to characterize structure–function relationships during white matter neuroplasticity. Biological sex differences may be an important factor that affects patterns of neuroplasticity, and therefore impacts learning and rehabilitation. …”
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Rapid neuroplasticity changes and response to intravenous ketamine: a randomized controlled trial in treatment-resistant depression by Jared Kopelman, Timothy A. Keller, Benjamin Panny, Angela Griffo, Michelle Degutis, Crystal Spotts, Nicolas Cruz, Elizabeth Bell, Kevin Do-Nguyen, Meredith L. Wallace, Sanjay J. Mathew, Robert H. Howland, Rebecca B. Price

“…Abstract Intravenous ketamine is posited to rapidly reverse depression by rapidly enhancing neuroplasticity. In human patients, we quantified gray matter microstructural changes on a rapid (24-h) timescale within key regions where neuroplasticity enhancements post-ketamine have been implicated in animal models. …”
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Neuroplasticity of pain processing and motor control in CAI patients: A UK Biobank study with clinical validation by Yiran Wang, Qianru Li, Xiao'ao Xue, Xiaoyun Xu, Weichu Tao, Sixu Liu, Yunyi Li, He Wang, He Wang, He Wang, Yinghui Hua, Yinghui Hua

“…BackgroundPain plays an important role in chronic ankle instability (CAI), and prolonged pain may be associated with ankle dysfunction and abnormal neuroplasticity.PurposeTo investigate the differences in resting-state functional connectivity among the pain-related brain regions and the ankle motor-related brain regions between healthy controls and patients with CAI, and explore the relationship between patients' motor function and pain.Study designA cross-database, cross-sectional study.MethodsThis study included a UK Biobank dataset of 28 patients with ankle pain and 109 healthy controls and a validation dataset of 15 patients with CAI and 15 healthy controls. …”
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Robot- and Technology-Boosting Neuroplasticity-Dependent Motor-Cognitive Functional Recovery: Looking towards the Future of Neurorehabilitation by Giovanni Morone, Marco Iosa, Rocco Salvatore Calabrò, Antonio Cerasa, Stefano Paolucci, Gabriella Antonucci, Irene Ciancarelli

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Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice by Melissa A. Ribeiro, Rafael P. Aguiar, Franciele F. Scarante, Eduardo J. Fusse, Rubia M. W. de Oliveira, Francisco S. Guimaraes, Alline C Campos

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Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses by Junfeng Su, Fengwen Huang, Yu Tian, Ran Tian, Gao Qianqian, Stephen Temitayo Bello, Dingxaun Zeng, Peter Jendrichovsky, C. Geoffrey Lau, Wenjun Xiong, Daiguan Yu, Micky Tortorella, Xi Chen, Jufang He

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Long-term spaceflight composite stress induces depression and cognitive impairment in astronauts—insights from neuroplasticity by Yishu Yin, Junlian Liu, Quanchun Fan, Shuang Zhao, Xiaorui Wu, Jiaping Wang, Yu Liu, Yongzhi Li, Weihong Lu

“…This review provides insights into LSCS and potential neuroplasticity mechanisms, current with potentially great impact for understanding and mitigating the mental health risks and traumas of career astronauts and space tourists.…”
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Single Exposure to the Cathinones MDPV and α-PVP Alters Molecular Markers of Neuroplasticity in the Adult Mouse Brain by Lucia Caffino, Francesca Mottarlini, Sabrine Bilel, Giorgia Targa, Micaela Tirri, Coralie Maggi, Matteo Marti, Fabio Fumagalli

“…While the cathinone-induced behavioral profile has been extensively investigated, information on their neuroplastic effects is still rather fragmentary. Accordingly, we have exposed male mice to a single injection of MDPV and α-PVP and sacrificed the animals at different time points (i.e., 30 min, 2 h, and 24 h) to have a rapid readout of the effect of these psychostimulants on neuroplasticity in the frontal lobe and hippocampus, two reward-related brain regions. …”
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A blended neurostimulation protocol to delineate cortico-muscular and spino-muscular dynamics following neuroplastic adaptation by Filip Stefanovic, Julian A. Martinez, Ghazala T. Saleem, Sue Ann Sisto, Michael T. Miller, Yaa A. Achampong, Albert H. Titus

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Book review of the adaptable mind: What neuroplasticity and neural reuse tells us about language and cognition by Xueyao Pan, Xi Li

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Multiple Neuroimaging Measures for Examining Exercise-induced Neuroplasticity in Older Adults: A Quasi-experimental Study by Lihong Wang, Lihong Wang, Lihong Wang, Lanxin Ji, Han Zhang, Han Zhang, Guy G. Potter, Yu-Feng Zang, Yu-Feng Zang, David C. Steffens, Hua Guo

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The Influence of Microglia on Neuroplasticity and Long-Term Cognitive Sequelae in Long COVID: Impacts on Brain Development and Beyond by Luana da Silva Chagas, Claudio Alberto Serfaty

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The experimental research on neuroplasticity in rats’ hippocampus subjected to chronic cerebral hypoperfusion and interfered by Modified Dioscorea Pills by H.B. Li, W.B. Liang, L. Zhou

“…So far the knowledge about neuroplasticity in CCH is little known and the underlying interfered mechanism by MDP on neuroplasticity has not yet been explored. …”
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The effects of long-term lactate and high-intensity interval training (HIIT) on brain neuroplasticity of aged mice by Zhou Lei, Soroosh Mozaffaritabar, Takuji Kawamura, Atsuko Koike, Attila Kolonics, Johanna Kéringer, Ricardo A. Pinho, Jingquan Sun, Ruonan Shangguan, Zsolt Radák

“…Subsequently, in the 2nd experiment, we investigated the long-term effects of 500 mg/kg lactate intervention and HIIT on brain neuroplasticity in aged mice (25–27 months).The results of the 1st experiment demonstrated that both HIIT and different doses of lactate intervention (500 mg/kg and 2000 mg/kg) positively impacted the neuroplasticity biomarker VEGF in the hippocampus of aging mice. …”
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Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity by Fass, Daniel M., Reis, Surya A., Ghosh, Balaram, Hennig, Krista M., Joseph, Nadine F., Zhao, Wen-Ning, Nieland, Thomas J.F., Guan, Ji-Song, Groves Kuhnle, Chelsea E., Tang, Weiping, Barker, Douglas D., Mazitschek, Ralph, Schreiber, Stuart L., Tsai, Li-Huei, Haggarty, Stephen J.

“…As a consequence, pharmacological enhancement of the transcriptional processes mediating long-term memory formation provides a potential therapeutic strategy for cognitive disorders involving aberrant neuroplasticity. Here we focus on the identification and characterization of small molecule inhibitors of histone deacetylases (HDACs) as enhancers of CREB (cAMP response element-binding protein)-regulated transcription and modulators of chromatin-mediated neuroplasticity. …”
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Neural plasticity in adult somatic sensory-motor systems / by Ebner, Ford F.

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Development of a Spinal Cord Injury Model Permissive to Study the Cardiovascular Effects of Rehabilitation Approaches Designed to Induce Neuroplasticity by Liisa Wainman, Erin L. Erskine, Mehdi Ahmadian, Thomas Matthew Hanna, Christopher R. West

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Influencing the effectiveness of post-stroke motor rehabilitation factors by D. V. Zaharov, V. A. Mihailov

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Oxidized Cell-Free DNA Rapidly Skews the Transcriptional Profile of Brain Cells toward Boosting Neurogenesis and Neuroplasticity by Anton D. Filev, Svetlana V. Kostyuk, Pavel E. Umriukhin, Vladimir M. Pisarev

“…The results show that the oxidized form of cfDNA positively regulates early gene expression of neurogenesis and neuroplasticity. At the same time, the question of whether chronic elevation of cfDNA concentration alters brain cells remains unexplored.…”
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Effects of bright light therapy on neuroinflammatory and neuroplasticity markers in a diurnal rodent model of Seasonal Affective Disorder by Allison Costello, Katrina Linning-Duffy, Carleigh Vandenbrook, Joseph S. Lonstein, Lily Yan

“…Following 4 weeks of treatment, the expression of several neuroinflammatory or plasticity markers was examined in the medial prefrontal cortex (mPFC), basolateral amygdala (BLA), and the CA1 of the dorsal hippocampus.Results For the neuroinflammatory markers, BLT reduced TNF-α in the BLA of females, and upregulated CD11b in the mPFC and IL6 in the BLA in males. For the neuroplasticity markers, BLT downregulated BDNF in the CA1 and TrkB in all three brain regions in females but upregulated BDNF in the BLA and CA1 in males.Conclusions These results indicate that the therapeutic effects of BLT on sleep, mood, and cognition may be attributed in part to mechanisms involving neuroinflammation and neuroplasticity in corticolimbic brain regions. …”
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