Sensitisation of cutaneous afferent neurotransmission to innocuous and noxious mechanical stimuli using topical prostaglandin E(2) (PGE(2)) by Evans, K, Scott, C, Bountra, C

Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain. by Le Masurier, M, Oldenzeil, W, Lehman, C, Cowen, P, Sharp, T

Chronic Low Dose Neutron Exposure Results in Altered Neurotransmission Properties of the Hippocampus-Prefrontal Cortex Axis in Both Mice and Rats by Balaji Krishnan, Chandramouli Natarajan, Krystyn Z. Bourne, Leila Alikhani, Juan Wang, Allison Sowa, Katherine Groen, Bayley Perry, Dara L. Dickstein, Janet E. Baulch, Charles L. Limoli, Richard A. Britten

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Angiotensinergic Neurotransmissions in the Medial Amygdala Nucleus Modulate Behavioral Changes in the Forced Swimming Test Evoked by Acute Restraint Stress in Rats by Camila Marchi-Coelho, Willian Costa-Ferreira, Lilian L. Reis-Silva, Carlos C. Crestani

“…Taken together, these results indicate an involvement of angiotensinergic neurotransmissions within the MeA in behavioral changes in the FST evoked by stress.…”
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Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease by Antonio Munafò, Anna Flavia Cantone, Giulia Di Benedetto, Giulia Di Benedetto, Sebastiano Alfio Torrisi, Chiara Burgaletto, Carlo Maria Bellanca, Carlo Maria Bellanca, Gabriella Gaudio, Giuseppe Broggi, Rosario Caltabiano, Gian Marco Leggio, Renato Bernardini, Renato Bernardini, Giuseppina Cantarella

“…Due to the multifactorial nature of the disease, involving impairment of cholinergic neurotransmission and immune system, previous attempts to find effective treatments have faced challenges.Methods: In such scenario, we attempted to investigate the effects of alpha-glyceryl-phosphoryl-choline (α-GPC), a cholinomimetic molecule, on neuroinflammation and memory outcome in the triple transgenic mouse model of AD (3xTg-AD). …”
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P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse by Lumei Huang, Paula Mut-Arbona, Bernadett Varga, Bibiana Török, János Brunner, Antonia Arszovszki, András Iring, Máté Kisfali, E. Sylvester Vizi, Beáta Sperlágh

“…To summarize, P2X7Rs participate in the modulation of GC excitatory neurotransmission in the DG via EC-GC pathway, contributing to pathological alterations of neuronal functions leading to neurodevelopmental disorders.…”
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Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway by Yaiza M. Arenas, Andrea Cabrera-Pastor, Nora Juciute, Eloy Mora-Navarro, Vicente Felipo

“…Hyperammonemia also increases glycinergic neurotransmission. These alterations contribute to cognitive and motor impairment. …”
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Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice by Mattia Volta, Dayne A Beccano-Kelly, Sarah A Paschall, Stefano Cataldi, Sarah E MacIsaac, Naila Kuhlmann, Chelsie A Kadgien, Igor Tatarnikov, Jesse Fox, Jaskaran Khinda, Emma Mitchell, Sabrina Bergeron, Heather Melrose, Matthew J Farrer, Austen J Milnerwood

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Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Biochemical and Behavioral Profiles of Phosphodiesterase Inhibition in Dopaminergic Neurotransmission by Akinori Nishi, Gretchen L. Snyder

“…Biochemical and behavioral profiles of PDE inhibition by selective inhibitors and/or genetic deletion related to dopaminergic neurotransmission are compared among those PDEs. The inhibition of PDE up-regulates cAMP/PKA signaling in three neuronal subtypes, resulting in the stimulation of dopamine synthesis at dopaminergic terminals, the inhibition of dopamine D2–receptor signaling in striatopallidal neurons, and the stimulation of dopamine D1–receptor signaling in striatonigral neurons. …”
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Dopaminergic Neurotransmission in Patients With Parkinson's Disease and Impulse Control Disorders: A Systematic Review and Meta-Analysis of PET and SPECT Studies by Alice Martini, Denise Dal Lago, Nicola M. J. Edelstyn, Matteo Salgarello, Fabio Lugoboni, Stefano Tamburin

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Navigating Like a Fly: <i>Drosophila melanogaster</i> as a Model to Explore the Contribution of Serotonergic Neurotransmission to Spatial Navigation by Ivana Gajardo, Simón Guerra, Jorge M. Campusano

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Essential oil of Pterocarpus santalinus L. alleviates behavioral impairments in social defeat stress-exposed mice by regulating neurotransmission and neuroinflammation by Ly Thi Huong Nguyen, Nhi Phuc Khanh Nguyen, Khoa Nguyen Tran, Ho Jin Choi, Il Soo Moon, Heung-Mook Shin, In-Jun Yang

“…Conclusion: Intranasal PSEO exhibited antidepressant-like effects on SDS-exposed mice, potentially through modulating stress hormone, neurotransmission, and neuroinflammation. Further investigation into the pharmacokinetics, bioavailability, and mechanisms of (+)-ledene, cedrol, and isoaromadendrene epoxide is needed.…”
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Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats by Masato Kinboshi, Saki Shimizu, Kentaro Tokudome, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Ryosuke Takahashi, Akio Ikeda, Yukihiro Ohno

“…On the other hand, the AP treatment enhanced depolarization-induced GABA release only in WT rats, and not in Lgi1-mutant rats, illustrating reduced GABAergic neurotransmission in primed Lgi1-mutant rats. The present results suggest that enhanced glutamatergic and reduced GABAergic neurotransmission are involved in the audiogenic seizure-susceptibility associated with Lgi1-mutation.…”
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Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice by Volta, M, Beccano-Kelly, DA, Paschall, SA, Cataldi, S, MacIsaac, SE, Kuhlmann, N, Kadgien, CA, Tatarnikov, I, Fox, J, Khinda, J, Mitchell, E, Bergeron, S, Melrose, H, Farrer, MJ, Milnerwood, AJ

Proteomic analysis of the maternal protein restriction rat model for schizophrenia: identification of translational changes in hormonal signaling pathways and glutamate neurotransmission. by Guest, P, Urday, S, Ma, D, Stelzhammer, V, Harris, L, Amess, B, Pietsch, S, Oheim, C, Ozanne, SE, Bahn, S

Glycolysis-Derived Compounds From Astrocytes That Modulate Synaptic Communication by Carlos-Alberto Gonçalves, Letícia Rodrigues, Larissa D. Bobermin, Caroline Zanotto, Adriana Vizuete, André Quincozes-Santos, Diogo O. Souza, Marina C. Leite

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Nitric Oxide: From Gastric Motility to Gastric Dysmotility by Eglantina Idrizaj, Chiara Traini, Maria Giuliana Vannucchi, Maria Caterina Baccari

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Epigenetic correlates of the psychological interventions outcomes: A systematic review and meta-analysis by Gaia Romana Pellicano, PhD, Sambucini Daniela, Ciacchella Chiara, Giusti Arianna, Aceto Paola, MD, PhD, Lai Carlo, PhD

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Genetically encoded tools for in vivo G‐protein‐coupled receptor agonist detection at cellular resolution by Kayla E. Kroning, Wenjing Wang

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Neuroinflammation microenvironment sharpens seizure circuit by Benjamin Villasana-Salazar, Annamaria Vezzani

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