Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons by Omar Hoseá Cabrera, Nemanja Useinovic, Stefan Maksimovic, Michelle Near, Nidia Quillinan, Slobodan M. Todorovic, Vesna Jevtovic-Todorovic

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Implication of synaptotagmins 4 and 7 in activity-dependent somatodendritic dopamine release in the ventral midbrain by Benoît Delignat-Lavaud, Charles Ducrot, Willemieke Kouwenhoven, Nina Feller, Louis-Éric Trudeau

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THE EFFECT OF GABAERGIC NEUROTRANSMISSION ON THE SEIZURE-RELATED ACTIVITY OF THE LATERODORSAL THALAMIC NUCLEI AND THE SOMATOSENSORY CORTEX IN AGENETIC MODEL OF ABSENCE EPILEPSY by Maryam Jafarian

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The impact of modifier genes on cone-rod dystrophy heterogeneity: An explorative familial pilot study and a hypothesis on neurotransmission impairment. by Luigi Donato, Simona Alibrandi, Concetta Scimone, Carmela Rinaldi, Angela Dascola, Alessandro Calamuneri, Rosalia D'Angelo, Antonina Sidoti

“…These genes encode key proteins involved in cone development and survival, and retina neurotransmission. Among analyzed variants, CACNG8c.*6819A>T and the new CCDC175 c.76C>T showed extremely low frequency in the control group, suggesting a key role on disease phenotypes. …”
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Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. by Pascal Bonaventure, Leah Aluisio, James Shoblock, Jamin D Boggs, Ian C Fraser, Brian Lord, Timothy W Lovenberg, Ruggero Galici

“…These results indicate that 5-HT₇ receptor antagonists might reverse cognitive deficits associated with NMDA receptor hypofunction by selectively normalizing glutamatergic neurotransmission.…”
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Regulation of Inhibitory Signaling at the Receptor and Cellular Level; Advances in Our Understanding of GABAergic Neurotransmission and the Mechanisms by Which It Is Disrupted in Epilepsy by Allison E. Tipton, Allison E. Tipton, Allison E. Tipton, Shelley J. Russek, Shelley J. Russek, Shelley J. Russek, Shelley J. Russek

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The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission by Vicky Chuong, Mehdi Farokhnia, Sophia Khom, Claire L. Pince, Sophie K. Elvig, Roman Vlkolinsky, Renata C.N. Marchette, George F. Koob, Marisa Roberto, Leandro F. Vendruscolo, Lorenzo Leggio

“…In conclusion, the GLP-1 analogue semaglutide decreased alcohol intake across different drinking models and species and modulated central GABA neurotransmission, providing support for clinical testing of semaglutide as a potentially novel pharmacotherapy for AUD.…”
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Identification of Neurotransmission and Synaptic Biological Processes Disrupted in Autism Spectrum Disorder Using Interaction Networks and Community Detection Analysis by Joana Vilela, Hugo Martiniano, Ana Rita Marques, João Xavier Santos, Muhammad Asif, Célia Rasga, Guiomar Oliveira, Astrid Moura Vicente

“…Hundreds of candidate genes have been implicated in ASD, including neurotransmission and synaptic (NS) genes; however, the genetic architecture of this disease is far from clear. …”
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Carbamazepine Reduces Sharp Wave-Ripple Complexes and Exerts Synapse-Specific Inhibition of Neurotransmission in Ex Vivo Hippocampal Slices by Timothy A. Simeone, Segewkal H. Heruye, Joseph A. Kostansek, Mary Y. Yeh, Stephanie A. Matthews, Kaeli K. Samson, Kristina A. Simeone

“…These results suggest that the synapse-specific CBZ inhibition of neurotransmission reduces SPW-Rs and that the CBZ inhibition of SPW-Rs may underlie the cognitive impairments observed with therapeutic doses of CBZ.…”
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The impact of modifier genes on cone-rod dystrophy heterogeneity: An explorative familial pilot study and a hypothesis on neurotransmission impairment by Luigi Donato, Simona Alibrandi, Concetta Scimone, Carmela Rinaldi, Angela Dascola, Alessandro Calamuneri, Rosalia D’Angelo, Antonina Sidoti

“…These genes encode key proteins involved in cone development and survival, and retina neurotransmission. Among analyzed variants, CACNG8c.*6819A>T and the new CCDC175 c.76C>T showed extremely low frequency in the control group, suggesting a key role on disease phenotypes. …”
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Neuropeptides, New Ligands of SARS-CoV-2 Nucleoprotein, a Potential Link between Replication, Inflammation and Neurotransmission by Julien Henri, Laetitia Minder, Kevin Mohanasundaram, Sébastien Dilly, Anne Goupil-Lamy, Carmelo Di Primo, Anny Slama Schwok

“…We suggest that the physiological role of these neuropeptides in neurotransmission, pain and vasodilation for cholecystokinin and substance P could be altered by binding to N. …”
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Elevated Vascular Sympathetic Neurotransmission and Remodelling Is a Common Feature in a Rat Model of Foetal Programming of Hypertension and SHR by Maria Sofia Vieira-Rocha, Joana Beatriz Sousa, Pilar Rodríguez-Rodríguez, Silvia Madaglena Arribas, Carmen Diniz

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The anxiolytic-like activity of water-soluble Moringa oleifera Lam. lectin is mediated via serotoninergic, noradrenergic, and dopaminergic neurotransmission by Leydianne Leite de Siqueira Patriota, Bárbara Raíssa Ferreira de Lima, Amanda de Oliveira Marinho, Jainaldo Alves da Costa, Luana Cassandra Breitenbach Barroso Coelho, Patrícia Maria Guedes Paiva, Michelle Melgarejo da Rosa, Thiago Henrique Napoleão

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Corrigendum: Patchouli alcohol improved diarrhea-predominant irritable bowel syndrome by regulating excitatory neurotransmission in the myenteric plexus of rats by Wanyu Chen, Lu Liao, Zitong Huang, Yulin Lu, Yukang Lin, Ying Pei, Shulin Yi, Chen Huang, Hongying Cao, Bo Tan

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Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors by Binglu Ye, Yawei Yuan, Rui Liu, Haitao Zhou, Yujie Li, Zhihao Sheng, Tianyu Li, Bing Zhang, Zhendong Xu, Yang Li, Zhiqiang Liu

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Pharmacokinetic Properties of the Novel Synthetic Cannabinoid 5F-APINAC and Its Influence on Metabolites Associated with Neurotransmission in Rabbit Plasma by Ksenia M. Shestakova, Natalia V. Mesonzhnik, Pavel A. Markin, Natalia E. Moskaleva, Andrey A. Nedorubov, Alex Brito, Elizaveta G. Appolonova, Roman M. Kuznetsov, Natalia L. Bochkareva, Alexey Kukharenko, Alexey V. Lyundup, Franco Tagliaro, Svetlana A. Appolonova

“…The pharmacokinetic properties of 5F-APINAC and its influence on metabolomics profiles associated with neurotransmission were investigated in rabbit plasma. Twelve rabbits divided into three groups received 1-mL 5F-APINAC at 0.1, 1 and 2 mg/kg. …”
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Differential effects of anodal transcranial direct current stimulation in healthy adults of younger and older age: inhibitory neurotransmission and behavior by Kirstin-Friederike eHeise, Martina eNiehoff, Jan eFeldheim, Gianpiero eLiuzzi, Christian eGerloff, Friedhelm C Hummel

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Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. by Deltheil, T, Guiard, B, Guilloux, J, Nicolas, L, Deloménie, C, Repérant, C, Le Maitre, E, Leroux-Nicollet, I, Benmansour, S, Coudoré, F, David, D, Gardier, A

“…As an example of the relevance of intracerebral microdialysis, this review will focus on our recent neurochemical results showing the impact of Brain-Derived Neurotrophic Factor (BDNF) on serotonergic neurotransmission in basal and stimulated conditions. Indeed, although the elevation of 5-HT outflow induced by chronic administration of selective serotonin reuptake inhibitors (SSRIs) causes an increase in BDNF protein levels and expression (mRNA) in the hippocampus of rodents, the reciprocal interaction has not been demonstrated yet. …”

Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats. by Li, D, Wang, L, Lee, C, Dawson, T, Paterson, D

Long-term effect of neuronal nitric oxide synthase over-expression on cardiac neurotransmission mediated by a lentiviral vector. by Wang, L, Li, D, Dawson, T, Paterson, D

“…Short-term over-expression of neuronal nitric oxide synthase (nNOS) with adenoviral gene transfer into peripheral cardiac autonomic neurons can facilitate cholinergic neurotransmission, and inhibit sympathetic transmission, by regulating cyclic nucleotide-dependent pathways coupled to neuronal calcium entry. …”