Preparation of ¹⁸F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [¹⁸F]Fluoride Exchange Reaction by Austin Craig, Jürgen Kogler, Markus Laube, Martin Ullrich, Cornelius K. Donat, Robert Wodtke, Klaus Kopka, Sven Stadlbauer

“…The emerging significance of the tumor microenvironment (TME) as a new frontier for cancer diagnosis and therapy may be exploited by radiolabeled tracers for diagnostic imaging techniques such as positron emission tomography (PET). …”
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Deep-Learning for the Diagnosis of Esophageal Cancers and Precursor Lesions in Endoscopic Images: A Model Establishment and Nationwide Multicenter Performance Verification Study by Eun Jeong Gong, Chang Seok Bang, Kyoungwon Jung, Su Jin Kim, Jong Wook Kim, Seung In Seo, Uhmyung Lee, You Bin Maeng, Ye Ji Lee, Jae Ick Lee, Gwang Ho Baik, Jae Jun Lee

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Targeting PIK3CA Actionable Mutations in the Circulome: A Proof of Concept in Metastatic Breast Cancer by Barbara Cardinali, Giuseppa De Luca, Roberta Tasso, Simona Coco, Anna Garuti, Giulia Buzzatti, Andrea Sciutto, Luca Arecco, Federico Villa, Franca Carli, Daniele Reverberi, Rodolfo Quarto, Mariella Dono, Lucia Del Mastro

“…The study of circulating cancer-derived components (circulome) is considered the new frontier of liquid biopsy. Despite the recognized role of circulome biomarkers, their comparative molecular profiling is not yet routine. …”
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Zebrafish Patient-Derived Xenograft Model to Predict Treatment Outcomes of Colorectal Cancer Patients by Gregorio Di Franco, Alice Usai, Margherita Piccardi, Perla Cateni, Matteo Palmeri, Luca Emanuele Pollina, Raffaele Gaeta, Federica Marmorino, Chiara Cremolini, Luciana Dente, Alessandro Massolo, Vittoria Raffa, Luca Morelli

“…Our results provide evidence that the zPDX model can reflect the outcome in mCRC patients, opening a new frontier to personalized medicine.…”
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Exercise Predicts a Good Night’s Sleep: Preliminary Findings from a UCLA Study of First-Episode Schizophrenia by Kenneth L. Subotnik, Sarah C. McEwen, Joseph Ventura, Luana Rene Turner, Yurika Sturdevant, Trudy L. Niess, Laurie R. Casaus, Margaret G. Distler, Michael F. Zito, Gerhard S. Hellemann, Clara D. Nguyen, Keith H. Nuechterlein

“…Understanding the negative impact of poor sleep quality on multiple domains of functioning among persons with schizophrenia is a new frontier of exploration. It is also imperative to investigate non-pharmacologic methods to improve sleep quality as these approaches may not carry the side effect burdens associated with medication. …”
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Treaty Conflicts in Investment Arbitration by Ahmad Ali Ghouri Review by Stephan Schill

“…The European Commission, for example, considers international investment law as the “new frontier for the common commercial policy” (COM(2010)343 final (7 July 2010) at 2). …”
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Treaty Conflicts in Investment Arbitration by Ahmad Ali Ghouri Review by Stephan Schill

“…The European Commission, for example, considers international investment law as the “new frontier for the common commercial policy” (COM(2010)343 final (7 July 2010) at 2). …”
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Atomically precise single metal oxide cluster catalyst with oxygen-controlled activity by Li, Xinzhe, Guo, Na, Chen, Zhongxin, Zhou, Xin, Zhao, Xiaoxu, Du, Yonghua, Ma, Lu, Fang, Yiyun, Xu, Haomin, Yang, Huimin, Yu, Wei, Lu, Shangchen, Tian, Mingjiao, He, Qian, Loh, Kian Ping, Xi, Shibo, Zhang, Chun, Lu, Jiong

“…Single cluster catalysts (SCCs) consisting of atomically precise metal nanoclusters dispersed on supports represent a new frontier of heterogeneous catalysis. However, the ability to synthesize SCCs with high loading and to precisely introduce non-metal atoms to further tune their catalytic activity and reaction scope of SCCs have been longstanding challenges. …”
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Covalent immobilization of α-CGTase on cellulose nanofiber derived from kenaf bast for enzymatic membrane reactor by Sulaiman, Safwan

“…Nanobiocatalyst is a new frontier of emerging nano-sized material support in enzyme immobilization application. …”
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Agricultural Biotechnology, Biodiversity and Bioresources Conservation and Utilization / by Obembe, Olawole O., editor 649891, Ekundayo, Emmanuel Olufemi, editor 650252, Okoli, Arinze Stanley, editor 650250, Gidado, Abubakar, editor 650251, Adetunji, Charles Oluwaseun, editor 649890, Ibrahim, Abdulrazak B., editor 650208, Ubi, Benjamin Ewa, 1968-, editor 649894, Biotechnology Society of Nigeria, issuing body 649895

Meta-omics integration approach reveals the effect of soil native microbiome diversity in the performance of inoculant Azospirillum brasilense by Jessica Aparecida Ferrarezi, Heloísa Defant, Leandro Fonseca de Souza, João Lúcio Azevedo, Mariangela Hungria, Maria Carolina Quecine

“…Furthermore, the interaction among PGPB and the holobiont (host-microbiome association) represent a new frontier to plant breeding programs. We aimed to characterize maize bulk soil and rhizosphere microbiomes in irradiated soil (IS) and a native soil (NS) microbial community gradient (dilution-to-extinction) with Azospirillum brasilense Ab-V5, a PGPB commercial inoculant. …”
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A highly sensitive electrochemical magneto-genosensing assay for the specific detection of a single nucleotide variation in the KRAS oncogene in human plasma by Simone Fortunati, Chiara Giliberti, Marco Giannetto, Alessandro Bertucci, Sabrina Capodaglio, Elena Ricciardi, Patrizio Giacomini, Valentina Bianchi, Andrea Boni, Ilaria De Munari, Roberto Corradini, Maria Careri

“…Liquid biopsy is a non-invasive and efficient technique for the detection of tumor biomarkers in biological fluids, which currently represents a new frontier in theranostics and precision medicine. …”
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New understandings on gas accumulation and major exploration breakthroughs in subsalt Ma 4 Member of Ordovician Majiagou Formation, Ordos Basin, NW China by Haiqing HE, Xujie GUO, Zhenyu ZHAO, Shengli XI, Jufeng WANG, Wei SONG, Junfeng REN, Xingning WU, He BI

“…The study has brought a historic breakthrough in the gas exploration of subsalt Ma 4 Member of Ordovician, and opened up a new frontier of gas exploration in the Ordos Basin.…”
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A pilot study on a patient with refractory headache: Personalized deep brain stimulation through stereoelectroencephalography by Hulin Zhao, Shuhua Zhang, Yining Wang, Chuting Zhang, Zihua Gong, Mingjie Zhang, Wei Dai, Ye Ran, Wenbin Shi, Yuanyuan Dang, Aijun Liu, Zhengbo Zhang, Chien-Hung Yeh, Zhao Dong, Shengyuan Yu

“…In this pilot study, the concept of the herein-proposed data-driven approach to optimizing precise and personalized treatment strategies for DBS may create a new frontier in the field of refractory headache and even pain disorders.…”
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Advancing application of mesenchymal stem cell-based bone tissue regeneration by Fengqing Shang, Yang Yu, Shiyu Liu, Leiguo Ming, Yongjie Zhang, Zhifei Zhou, Jiayu Zhao, Yan Jin

“…Advances in our understanding of regenerative biomaterials and their roles in new bone formation potentially opened a new frontier in the fast-growing field of regenerative medicine. …”
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High ApoB/ApoA-I Ratio Predicts Post-Stroke Cognitive Impairment in Acute Ischemic Stroke Patients with Large Artery Atherosclerosis by Minwoo Lee, Jae-Sung Lim, Yerim Kim, Soo Hyun Park, Sang-Hwa Lee, Chulho Kim, Byung-Chul Lee, Kyung-Ho Yu, Jae-Jun Lee, Mi Sun Oh

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Under pressure: macro-ecological patterns in the benthic macrofauna in the northwest Atlantic deep sea by van der Grient, J

“…The deep sea is important in the climatic regulation of Earth, and it is a new frontier for resource provisioning for humanity. …”

Passive forward scatter radar based on LTE signal for vehicle detection and classification by Abdul Aziz, Noor Hafizah

“…Hence, it opens up a new frontier in passive radar that can be used for many applications including border protection, microwave fences, building monitoring, traffic surveillance, and so forth.…”
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Microbial Biofilms : Properties and Applications in the Environment, Agriculture, and Medicine / by Abdul, Bakrudeen Ali Ahmed, editor 636638

Early Detection of Prostate Cancer: The Role of Scent by Fabio Grizzi, Carmen Bax, Mohamed A. A. A. Hegazi, Beatrice Julia Lotesoriere, Matteo Zanoni, Paolo Vota, Rodolfo Fausto Hurle, Nicolò Maria Buffi, Massimo Lazzeri, Lorenzo Tidu, Laura Capelli, Gianluigi Taverna

“…Despite the prostate-specific antigen serum (PSA) levels, prostate biopsy, and imaging representing the actual gold-standard for diagnosing PCa, analyzing volatile organic compounds (VOCs) has emerged as a promising new frontier. We and other authors have reported that highly trained dogs can recognize specific VOCs associated with PCa with high accuracy. …”
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