Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity by Mazzoni, Esteban O., Mahony, Shaun, Closser, Michael, Morrison, Carolyn A., Nedelec, Stephane, Williams, Damian J, An, Disi, Wichterle, Hynek, Gifford, David K.

“…Efficient transcriptional programming promises to open new frontiers in regenerative medicine. However, mechanisms by which programming factors transform cell fate are unknown, preventing more rational selection of factors to generate desirable cell types. …”
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Optogenetic control of heart rhythm by selective stimulation of cardiomyocytes derived from Pnmt+ cells in murine heart by Wang, Y, Lin, W, Crawford, W, Ni, H, Bolton, E, Khan, H, Shanks, J, Bub, G, Wang, X, Paterson, D, Zhang, H, Galione, A, Ebert, S, Terrar, D, Lei, M

“…Our new murine model effectively demonstrates functional dissection of cardiomyocyte subpopulations using optogenetics, and opens new frontiers of exploration into their physiological roles in normal heart function as well as their potential application for selective cardiac repair and regeneration strategies.…”

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils by Kaur, G, Kaundal, S, Kapoor, S, Grimes, J, Huiskonen, J, Thakur, K

“…The discovery of the amyloidogenic property of an essential cytosolic global transcription regulator, CarD, in a pathogenic bacteria will further open up new frontiers in research.…”

Space odyssey : a voyage to the planets / by Haines, Tim, author 565573, Riley, Christopher, author 565574

“…Demanding the courage to face incredible dangers, it is a quest that will define new frontiers for our species. This is the story of Project Pegasus, the first manned voyage to the planets. …”

Quantitative Imaging Biomarkers in Age-Related Macular Degeneration and Diabetic Eye Disease: A Step Closer to Precision Medicine by Gagan Kalra, Sudeshna Sil Kar, Duriye Damla Sevgi, Anant Madabhushi, Sunil K. Srivastava, Justis P. Ehlers

“…These quantifiable biomarkers and automated approaches have unleashed new frontiers of personalized medicine where treatments are tailored, based on patient-specific longitudinally trackable biomarkers, and response monitoring can be achieved with a high degree of accuracy.…”
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Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors by Maria Teresa Masucci, Maria Letizia Motti, Michele Minopoli, Gioconda Di Carluccio, Maria Vincenza Carriero

“…Today, based on the identification of new driving oncogenic mutations, targeted therapy and precision medicine are regarded as the new frontiers for GISTs. This article reviews the most important mutations in GISTs and highlights their importance in the current understanding and treatment options of GISTs, with an emphasis on the most recent clinical trials.…”
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Development of a microfluidic-assisted open-source 3D bioprinting system (MOS3S) for the engineering of hierarchical tissues by Sajad Mohammadi, Salvatore D’Alessandro, Fabiano Bini, Franco Marinozzi, Gianluca Cidonio

“…MOS3S performance have been validated to fabricate high-resolution structures with coaxial microfluidic technology, opening to new frontiers for seminal studies in pre-clinical disease modelling and tissue regeneration.…”
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See Elegans: Simple-to-use, accurate, and automatic 3D detection of neural activity from densely packed neurons. by Enrico Lanza, Valeria Lucente, Martina Nicoletti, Silvia Schwartz, Ilaria F Cavallo, Davide Caprini, Christopher W Connor, Mashel Fatema A Saifuddin, Julia M Miller, Noelle D L'Etoile, Viola Folli

“…In the emerging field of whole-brain imaging at single-cell resolution, which represents one of the new frontiers to investigate the link between brain activity and behavior, the nematode Caenorhabditis elegans offers one of the most characterized models for systems neuroscience. …”
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Inside Out: Organizations as Service Systems Equipped with Relational Boundaries by María Jimena Crespo Garrido, Mara Grimaldi, Gennaro Maione, Massimiliano Vesci

“…This paper also offers some insights for future research, suggesting that both scholars and professionals investigate, firstly, new frontiers for the identification of organizational boundaries and, secondly, the possible positive repercussions that new organizational redesign modes could determine for a greater competitive success.…”
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The challenges of pricing quantity surveying professional services in Ghana by Michael Adesi, Degraft Owusu-Manu, Frank Boateng, Michael Nii Addy, Ernest Kissi

“…The paper also has the practical importance of opening up new frontiers of research that focus on pricing of professional services in the built environment in general. …”
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Progress of research on the diagnosis and treatment of bone cystic echinococcosis by Yibin Meng, Qian Ren, Jun Xiao, Haohao Sun, Yiping Huang, Yaqing Liu, Shan Wang, Sibo Wang

“…The development of novel antigens can open new frontiers in the diagnosis of the disease. Currently, views conflict on how to diagnose and treat bone CE. …”
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Advances in Extracellular Vesicle Nanotechnology for Precision Theranostics by Qian Wu, Siyuan Fu, Hanyang Xiao, Jiaxin Du, Fang Cheng, Shuangshuang Wan, Houjuan Zhu, Dan Li, Fei Peng, Xianguang Ding, Lianhui Wang

“…Many studies suggest that EVs are superior to conventional synthetic carriers in terms of drug delivery and circulating biomarkers for early disease diagnosis, opening up new frontiers for modern theranostics. Despite these clinical potential, EVs containing diverse cellular components, such as nucleic acids, proteins, and metabolites are highly heterogeneous and small size. …”
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Revues qui comptent, revues qu’on compte :produire des classements en économie et gestion by David Pontille, Didier Torny

“…Therefore, they are submitted to an ever going publication/uses/revisions cycle, providing new frontiers and professional norms.…”
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Placental Dysfunction in Assisted Reproductive Pregnancies: Perinatal, Neonatal and Adult Life Outcomes by Claudio Manna, Valentina Lacconi, Giuseppe Rizzo, Antonino De Lorenzo, Micol Massimiani

“…Prevention and treatment of these conditions represent new frontiers for clinicians and biologists involved in ART, and synergic actions with researchers at molecular levels are advocated.…”
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Highly efficient octave-spanning long-wavelength infrared generation with a 74% quantum efficiency in a χ (2) waveguide by Bo Hu, Xuemei Yang, Jiangen Wu, Siyi Lu, Hang Yang, Zhe Long, Linzhen He, Xing Luo, Kan Tian, Weizhe Wang, Yang Li, Han Wu, Wenlong Li, Chunyu Guo, Huan Yang, Qi Jie Wang, Houkun Liang

“…Our prototype micro-waveguide platform could be extended to other χ (2) birefringence crystals and trigger new frontiers of MIR integrated nonlinear photonics.…”
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Epigenetic-Mediated Antimicrobial Resistance: Host versus Pathogen Epigenetic Alterations by Jibran Sualeh Muhammad, Naveed Ahmed Khan, Sutherland K. Maciver, Ahmad M. Alharbi, Hasan Alfahemi, Ruqaiyyah Siddiqui

“…As genetic mechanisms cannot explain the transient nature of antimicrobial resistance, we believe that epigenetics may provide new frontiers in antimicrobial discovery.…”
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The REgolith X-Ray Imaging Spectrometer (REXIS) for OSIRIS-REx: identifying regional elemental enrichment on asteroids by Allen, Branden, Grindlay, Jonathan E., Hong, Jaesub, Inamdar, Niraj K., Bautz, Marshall W., Kissel, Steve E., Oprescu, Miruna, Induni, Nicholas, Masterson, Rebecca A., Chodas, Mark A., Smith, Matthew William, Villasenor, Jesus Noel Samonte, Kissel, Steve E., Binzel, Richard P

“…The OSIRIS-REx Mission was selected under the NASA New Frontiers program and is scheduled for launch in September of 2016 for a rendezvous with, and collection of a sample from the surface of asteroid Bennu in 2019. 101955 Bennu (previously 1999 RQ36) is an Apollo (near-Earth) asteroid originally discovered by the LINEAR project in 1999 which has since been classified as a potentially hazardous near-Earth object. …”
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Highly efficient octave-spanning long-wavelength infrared generation with a 74% quantum efficiency in a χ(2) waveguide by Hu, Bo, Yang, Xuemei, Wu, Jiangen, Lu, Siyi, Yang, Hang, Long, Zhe, He, Linzhen, Luo, Xing, Tian, Kan, Wang, Weizhe, Li, Yang, Wu, Han, Li, Wenlong, Guo, Chunyu, Yang, Huan, Wang, Qi Jie, Liang, Houkun

“…Our prototype micro-waveguide platform could be extended to other χ(2) birefringence crystals and trigger new frontiers of MIR integrated nonlinear photonics.…”
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Circuit quantum acoustodynamics with surface acoustic waves by Manenti, R, Kockum, A, Patterson, A, Behrle, T, Rahamim, J, Tancredi, G, Nori, F, Leek, P

“…The experimental investigation of quantum devices incorporating mechanical resonators has opened up new frontiers in the study of quantum mechanics at a macroscopic level. …”

A critical review of state-of-the-art and emerging approaches to identify fracking-derived gases and associated contaminants in aquifers by McIntosh, J, Hendry, M, Ballentine, C, Haszeldine, R, Mayer, B, Etiope, G, Elsner, M, Darrah, T, Prinzhofer, A, Osborn, S, Stalker, L, Kuloyo, O, Lu, Z, Martini, A, Lollar, B

“…These approaches may also be applied to broader subsurface exploration and development issues (e.g., groundwater resources), or new frontiers of low-carbon energy alternatives (e.g., subsurface H2 storage, nuclear waste isolation, geologic CO2 sequestration).…”