Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance by Mehmet Umut Akyol, Tord D. Alden, Hernan Amartino, Jane Ashworth, Kumar Belani, Kenneth I. Berger, Andrea Borgo, Elizabeth Braunlin, Yoshikatsu Eto, Jeffrey I. Gold, Andrea Jester, Simon A. Jones, Cengiz Karsli, William Mackenzie, Diane Ruschel Marinho, Andrew McFadyen, Jim McGill, John J. Mitchell, Joseph Muenzer, Torayuki Okuyama, Paul J. Orchard, Bob Stevens, Sophie Thomas, Robert Walker, Robert Wynn, Roberto Giugliani, Paul Harmatz, Christian Hendriksz, Maurizio Scarpa, MPS Consensus Programme Steering Committee, MPS Consensus Programme Co-Chairs

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Comparison of four handheld point-of-care ultrasound devices by expert users by Minh-Phuong T. Le, Lara Voigt, Robert Nathanson, Anna M. Maw, Gordon Johnson, Ria Dancel, Benji Mathews, Alvaro Moreira, Harald Sauthoff, Christopher Gelabert, Linda M. Kurian, Jenna Dumovich, Kevin C. Proud, Jessica Solis-McCarthy, Carolina Candotti, Christopher Dayton, Alexander Arena, Brandon Boesch, Saul Flores, Mark T. Foster, Nicholas Villalobos, Tanping Wong, Gabriel Ortiz-Jaimes, Michael Mader, Craig Sisson, Nilam J. Soni

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The Burden of Atherosclerotic Cardiovascular Disease in South Asians Residing in Canada: A Reflection From the South Asian Heart Alliance by Kevin R. Bainey, MD, MSc, Milan Gupta, MD, Imtiaz Ali, MD, Sripal Bangalore, MD, Maria Chiu, PhD, Kendeep Kaila, MD, Padma Kaul, PhD, Nadia Khan, MD, Kathryn M. King-Shier, RN, PhD, Latha Palaniappan, MD, MS, Guillaume Pare, MD, MSc, Krish Ramanathan, MD, Stephanie Ross, MSc, PhD, Baiju R. Shah, MD, PhD

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Consensus on DEfinition of Food Allergy SEverity (DEFASE) an integrated mixed methods systematic review by Stefania Arasi, Ulugbek Nurmatov, Audrey Dunn-Galvin, Shahd Daher, Graham Roberts, Paul J. Turner, Sayantani B. Shinder, Ruchi Gupta, Philippe Eigenmann, Anna Nowak-Wegrzyn, Mario A. Sánchez Borges, Ignacio J. Ansotegui, Montserrat Fernandez-Rivas, Stavros Petrou, Luciana Kase Tanno, Marta Vazquez-Ortiz, Brian P. Vickery, Gary Wing-Kin Wong, Motohiro Ebisawa, Alessandro Fiocchi

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Perioperative lumbar plexus block and cardiac ischemia in patients with hip fracture: randomized clinical trial by Fernando R. Altermatt, Ghislaine C. Echevarría, René F. De la Fuente, Ricardo Baeza, Marcela Ferrada, Juan C. De la Cuadra, Marcia A. Corvetto

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The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder by Cees J. Weeland, Selina Kasprzak, Niels T. de Joode, Yoshinari Abe, Pino Alonso, Stephanie H. Ameis, Alan Anticevic, Paul D. Arnold, Srinivas Balachander, Nerisa Banaj, Nuria Bargallo, Marcelo C. Batistuzzo, Francesco Benedetti, Jan C. Beucke, Irene Bollettini, Vilde Brecke, Silvia Brem, Carolina Cappi, Yuqi Cheng, Kang Ik K. Cho, Daniel L. C. Costa, Sara Dallaspezia, Damiaan Denys, Goi Khia Eng, Sónia Ferreira, Jamie D. Feusner, Martine Fontaine, Jean-Paul Fouche, Rachael G. Grazioplene, Patricia Gruner, Mengxin He, Yoshiyuki Hirano, Marcelo Q. Hoexter, Chaim Huyser, Hao Hu, Fern Jaspers-Fayer, Norbert Kathmann, Christian Kaufmann, Minah Kim, Kathrin Koch, Yoo Bin Kwak, Jun Soo Kwon, Luisa Lazaro, Chiang-shan R. Li, Christine Lochner, Rachel Marsh, Ignacio Martínez-Zalacaín, David Mataix-Cols, Jose M. Menchón, Luciano Minnuzi, Pedro Silva Moreira, Pedro Morgado, Akiko Nakagawa, Takashi Nakamae, Janardhanan C. Narayanaswamy, Erika L. Nurmi, Ana E. Ortiz, Jose C. Pariente, John Piacentini, Maria Picó-Pérez, Fabrizio Piras, Federica Piras, Christopher Pittenger, Y. C. Janardhan Reddy, Daniela Rodriguez-Manrique, Yuki Sakai, Eiji Shimizu, Venkataram Shivakumar, Helen Blair Simpson, Noam Soreni, Carles Soriano-Mas, Nuno Sousa, Gianfranco Spalletta, Emily R. Stern, Michael C. Stevens, S. Evelyn Stewart, Philip R. Szeszko, Jumpei Takahashi, Tais Tanamatis, Jinsong Tang, Anders Lillevik Thorsen, David Tolin, Ysbrand D. van der Werf, Hein van Marle, Guido A. van Wingen, Daniela Vecchio, G. Venkatasubramanian, Susanne Walitza, Jicai Wang, Zhen Wang, Anri Watanabe, Lidewij H. Wolters, Xiufeng Xu, Je-Yeon Yun, Qing Zhao, ENIGMA OCD Working Group, Tonya White, Paul M. Thompson, Dan J. Stein, Odile A. van den Heuvel, Chris Vriend

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Targeting the pregnane X receptor using microbial metabolite mimicry by Zdeněk Dvořák, Felix Kopp, Cait M Costello, Jazmin S Kemp, Hao Li, Aneta Vrzalová, Martina Štěpánková, Iveta Bartoňková, Eva Jiskrová, Karolína Poulíková, Barbora Vyhlídalová, Lars U Nordstroem, Chamini V Karunaratne, Harmit S Ranhotra, Kyu Shik Mun, Anjaparavanda P Naren, Iain A Murray, Gary H Perdew, Julius Brtko, Lucia Toporova, Arne Schön, Bret D Wallace, William G Walton, Matthew R Redinbo, Katherine Sun, Amanda Beck, Sandhya Kortagere, Michelle C Neary, Aneesh Chandran, Saraswathi Vishveshwara, Maria M Cavalluzzi, Giovanni Lentini, Julia Yue Cui, Haiwei Gu, John C March, Shirshendu Chatterjee, Adam Matson, Dennis Wright, Kyle L Flannigan, Simon A Hirota, Ryan Balfour Sartor, Sridhar Mani

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Association Between Self-Reported Polycystic Ovary Syndrome with Chronic Diseases Among Emiratis: A Cross-Sectional Analysis from the UAE Healthy Future Study by Juber NF, Abdulle A, AlJunaibi A, AlNaeemi A, Ahmad A, Leinberger-Jabari A, Al Dhaheri AS, AlZaabi E, Al-Maskari F, AlAnouti F, Alsafar H, Alkaabi J, Wareth LA, Aljaber M, Kazim M, Weitzman M, Al-Houqani M, Hag-Ali M, Oumeziane N, Sherman S, Shah SM, Almahmeed W, Idaghdour Y, Loney T, El-Shahawy O, Ali R

“…Nirmin F Juber,1 Abdishakur Abdulle,1 Abdulla AlJunaibi,2 Abdulla AlNaeemi,3 Amar Ahmad,1 Andrea Leinberger-Jabari,1 Ayesha S Al Dhaheri,4 Eiman AlZaabi,5 Fatma Al-Maskari,6,7 Fatme AlAnouti,8 Habiba Alsafar,9– 11 Juma Alkaabi,12 Laila Abdel Wareth,13 Mai Aljaber,14 Marina Kazim,15 Michael Weitzman,16 Mohammad Al-Houqani,17 Mohammed Hag-Ali,18 Naima Oumeziane,15 Scott Sherman,19 Syed M Shah,6 Wael Almahmeed,20 Youssef Idaghdour,1 Tom Loney,21 Omar El-Shahawy,19 Raghib Ali1,22 1Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates; 2Department of Pediatrics, Zayed Military Hospital, Abu Dhabi, United Arab Emirates; 3Department of Cardiology, Zayed Military Hospital, Abu Dhabi, United Arab Emirates; 4Department of Nutrition and Health, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates; 5Department of Pathology, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates; 6Institute of Public Health, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates; 7Zayed Center for Health Sciences, UAE University, Al-Ain, United Arab Emirates; 8College of Natural and Health Sciences, Zayed University, Abu Dhabi, United Arab Emirates; 9Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates; 10Department of Genetics and Molecular Biology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates; 11Department of Biomedical Engineering, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates; 12Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates; 13The National Reference Laboratory, Abu Dhabi, United Arab Emirates; 14Healthpoint Hospital, Abu Dhabi, United Arab Emirates; 15Abu Dhabi Blood Bank Services, SEHA, Abu Dhabi, United Arab Emirates; 16Department of Environmental Medicine, New York University of Medicine, New York, NY, USA; 17Department of Medicine, College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates; 18Faculty of Health Sciences, Higher Colleges of Technology, Abu Dhabi, United Arab Emirates; 19Department of Population Health, New York University School of Medicine, New York, NY, USA; 20Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; 21College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates; 22MRC Epidemiology Unit, University of Cambridge, Cambridge, UKCorrespondence: Nirmin F Juber, Public Health Research Center, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates, Tel +971-2-6287631, Email nirmin.juber@nyu.eduPurpose: This study aimed to assess the prevalence of self-reported polycystic ovary syndrome (PCOS) among Emiratis and examine bi-directional associations of PCOS with self-reported chronic diseases, namely: diabetes, asthma, high cholesterol, and high blood pressure.Patients and Methods: A cross-sectional analysis was performed using the UAE Healthy Future Study (UAEHFS) data collected from February 2016 to April 2022 involving 1040 Emirati women aged 25– 67 years from recruitment centers in the United Arab Emirates (UAE). …”
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Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis by Ada Weinstock, Karishma Rahman, Or Yaacov, Hitoo Nishi, Prashanthi Menon, Cyrus A Nikain, Michela L Garabedian, Stephanie Pena, Naveed Akbar, Brian E Sansbury, Sean P Heffron, Jianhua Liu, Gregory Marecki, Dawn Fernandez, Emily J Brown, Kelly V Ruggles, Stephen A Ramsey, Chiara Giannarelli, Matthew Spite, Robin P Choudhury, P'ng Loke, Edward A Fisher

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Humoral immune responses against SARS-CoV-2 Spike variants after mRNA vaccination in solid organ transplant recipients by Alexandra Tauzin, Guillaume Beaudoin-Bussières, Shang Yu Gong, Debashree Chatterjee, Gabrielle Gendron-Lepage, Catherine Bourassa, Guillaume Goyette, Normand Racine, Zineb Khrifi, Julie Turgeon, Cécile Tremblay, Valérie Martel-Laferrière, Daniel E. Kaufmann, Héloïse Cardinal, Marc Cloutier, Renée Bazin, Ralf Duerr, Mélanie Dieudé, Marie-Josée Hébert, Andrés Finzi

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Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts by Kuanrong Li, Garnet Anderson, Vivian Viallon, Patrick Arveux, Marina Kvaskoff, Agnès Fournier, Vittorio Krogh, Rosario Tumino, Maria-Jose Sánchez, Eva Ardanaz, María-Dolores Chirlaque, Antonio Agudo, David C. Muller, Todd Smith, Ioanna Tzoulaki, Timothy J. Key, Bas Bueno-de-Mesquita, Antonia Trichopoulou, Christina Bamia, Philippos Orfanos, Rudolf Kaaks, Anika Hüsing, Renée T. Fortner, Anne Zeleniuch-Jacquotte, Malin Sund, Christina C. Dahm, Kim Overvad, Dagfinn Aune, Elisabete Weiderpass, Isabelle Romieu, Elio Riboli, Marc J. Gunter, Laure Dossus, Ross Prentice, Pietro Ferrari

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Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx by Shaoyi Wang, Weiwei Li, Pengfei Zhang, Zihao Wang, Xiaoyuan Ma, Chuanju Liu, Krasimir Vasilev, Lei Zhang, Xiaocong Zhou, Liang Liu, John Hayball, Shuli Dong, Yuhua Li, Yuan Gao, Lei Cheng, Yunpeng Zhao

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Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk by Cameron B. Haas, Yu-Ru Su, Paneen Petersen, Xiaoliang Wang, Stephanie A. Bien, Yi Lin, Demetrius Albanes, Stephanie J. Weinstein, Mark A. Jenkins, Jane C. Figueiredo, Polly A. Newcomb, Graham Casey, Loic Le Marchand, Peter T. Campbell, Victor Moreno, John D. Potter, Lori C. Sakoda, Martha L. Slattery, Andrew T. Chan, Li Li, Graham G. Giles, Roger L. Milne, Stephen B. Gruber, Gad Rennert, Michael O. Woods, Steven J. Gallinger, Sonja Berndt, Richard B. Hayes, Wen-Yi Huang, Alicja Wolk, Emily White, Hongmei Nan, Rami Nassir, Noralane M. Lindor, Juan P. Lewinger, Andre E. Kim, David Conti, W. James Gauderman, Daniel D. Buchanan, Ulrike Peters, Li Hsu

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Interactive Associations of Neuropsychiatry Inventory-Questionnaire Assessed Sleep Disturbance and Vascular Risk on Alzheimer’s Disease Stage Progression in Clinically Normal Older... by Omonigho M. Bubu, Omonigho M. Bubu, Ellita T. Williams, Ogie Q. Umasabor-Bubu, Sonya S. Kaur, Arlener D. Turner, Judite Blanc, Jaime Ramos Cejudo, Anna E. Mullins, Ankit Parekh, Korey Kam, Zainab T. Osakwe, Ann W. Nguyen, Antoine R. Trammell, Alfred K. Mbah, Mony de Leon, David M. Rapoport, Indu Ayappa, Gbenga Ogedegbe, Girardin Jean-Louis, Girardin Jean-Louis, Arjun V. Masurkar, Andrew W. Varga, Ricardo S. Osorio, Ricardo S. Osorio

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Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study by Lindsay R. Freud, Doff B. McElhinney, Brian T. Kalish, Maria C. Escobar‐Diaz, Rukmini Komarlu, Michael D. Puchalski, Edgar T. Jaeggi, Anita L. Szwast, Grace Freire, Stéphanie M. Levasseur, Ann Kavanaugh‐McHugh, Erik C. Michelfelder, Anita J. Moon‐Grady, Mary T. Donofrio, Lisa W. Howley, Elif Seda Selamet Tierney, Bettina F. Cuneo, Shaine A. Morris, Jay D. Pruetz, Mary E. van der Velde, John P. Kovalchin, Catherine M. Ikemba, Margaret M. Vernon, Cyrus Samai, Gary M. Satou, Nina L. Gotteiner, Colin K. Phoon, Norman H. Silverman, Wayne Tworetzky

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Associations between serum 25-hydroxyvitamin D, body mass index and body fat composition among Emirati population: Results from the UAE healthy future study by Fatme AlAnouti, Amar Sabri Ahmad, Laila Abdel Wareth, Ayesha Al Dhaheri, Abderrahim Oulhaj, Abdulla Al Junaibi, Abdullah Al Naeemi, Aisha Al Hamiz, Ayesha Al Hosani, Eiman Al Zaabi, Fatima Mezhal, Fatma Al Maskari, Fatma Al Maskari, Habiba Alsafar, Habiba Alsafar, Habiba Alsafar, Jamila Yaaqoub, Marina Al Bastaki, Mohammed Al Houqani, Naima Oumeziane, Nirmin F. Juber, Scott Sherman, Syed M. Shah, Teeb Alsharid, Thekra Al Zaabi, Tom Loney, Wael Al Mahmeed, Abdishakur Abdulle, Raghib Ali, Raghib Ali

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Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop by Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M. Coussens, Daniel D. De Carvalho, David G. DeNardo, Jérôme Galon, Howard L. Kaufman, Tomas Kirchhoff, Michael T. Lotze, Jason J. Luke, Andy J. Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B. Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M. Barnes, Valentin Barsan, Praveen K. Bommareddy, Adrian Bot, Sarah E. Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S. Ho, Heather M. McGee, Anne Monette, Joseph F. Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F. Sweis, Sara Valpione, Roberta Zappasodi, Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, Alessandra Cesano, Francesco M. Marincola, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups

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Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset by Sai Priya Anand, Jérémie Prévost, Manon Nayrac, Guillaume Beaudoin-Bussières, Mehdi Benlarbi, Romain Gasser, Nathalie Brassard, Annemarie Laumaea, Shang Yu Gong, Catherine Bourassa, Elsa Brunet-Ratnasingham, Halima Medjahed, Gabrielle Gendron-Lepage, Guillaume Goyette, Laurie Gokool, Chantal Morrisseau, Philippe Bégin, Valérie Martel-Laferrière, Cécile Tremblay, Jonathan Richard, Renée Bazin, Ralf Duerr, Daniel E. Kaufmann, Andrés Finzi

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Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among adults exposed to coronavirus d... by Ruanne V. Barnabas, Elizabeth Brown, Anna Bershteyn, R. Scott Miller, Mark Wener, Connie Celum, Anna Wald, Helen Chu, David Wesche, Jared M. Baeten, for the Hydroxychloroquine COVID-19 PEP Study Team

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Genetically Determined Height and Risk of Non-hodgkin Lymphoma by Amy Moore, Eleanor Kane, Zhaoming Wang, Zhaoming Wang, Orestis A. Panagiotou, Orestis A. Panagiotou, Lauren R. Teras, Alain Monnereau, Alain Monnereau, Alain Monnereau, Nicole Wong Doo, Mitchell J. Machiela, Christine F. Skibola, Susan L. Slager, Gilles Salles, Gilles Salles, Gilles Salles, Nicola J. Camp, Paige M. Bracci, Alexandra Nieters, Roel C. H. Vermeulen, Roel C. H. Vermeulen, Joseph Vijai, Karin E. Smedby, Karin E. Smedby, Yawei Zhang, Claire M. Vajdic, Wendy Cozen, Wendy Cozen, John J. Spinelli, John J. Spinelli, Henrik Hjalgrim, Graham G. Giles, Graham G. Giles, Brian K. Link, Jacqueline Clavel, Jacqueline Clavel, Alan A. Arslan, Alan A. Arslan, Alan A. Arslan, Mark P. Purdue, Lesley F. Tinker, Demetrius Albanes, Giovanni M. Ferri, Thomas M. Habermann, Hans-Olov Adami, Hans-Olov Adami, Nikolaus Becker, Yolanda Benavente, Yolanda Benavente, Simonetta Bisanzi, Paolo Boffetta, Paul Brennan, Angela R. Brooks-Wilson, Angela R. Brooks-Wilson, Federico Canzian, Lucia Conde, David G. Cox, Karen Curtin, Lenka Foretova, Susan M. Gapstur, Hervé Ghesquières, Hervé Ghesquières, Martha Glenn, Bengt Glimelius, Rebecca D. Jackson, Qing Lan, Mark Liebow, Marc Maynadie, James McKay, Mads Melbye, Mads Melbye, Lucia Miligi, Roger L. Milne, Roger L. Milne, Thierry J. Molina, Lindsay M. Morton, Kari E. North, Kari E. North, Kenneth Offit, Marina Padoan, Alpa V. Patel, Sara Piro, Vignesh Ravichandran, Elio Riboli, Silvia de Sanjose, Silvia de Sanjose, Richard K. Severson, Melissa C. Southey, Anthony Staines, Carolyn Stewart, Ruth C. Travis, Elisabete Weiderpass, Stephanie Weinstein, Tongzhang Zheng, Stephen J. Chanock, Nilanjan Chatterjee, Nilanjan Chatterjee, Nilanjan Chatterjee, Nathaniel Rothman, Brenda M. Birmann, James R. Cerhan, Sonja I. Berndt

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