Broad Environmental Tolerance for a <i>Salicola</i> Host-Phage Pair Isolated from the Cargill Solar Saltworks, Newark, CA, USA by Meghan L. Rodela, Shereen Sabet, Allison Peterson, Jesse G. Dillon

“…This study describes a comparative investigation of physicochemical tolerance between a strain of the halophilic bacterium, <i>Salicola</i>, isolated from the Cargill Saltworks (Newark, CA, USA) and its associated phage. The host grew in media between pH 6&#8211;8.5, had a salinity growth optimum of 20% total salts (ranging from 10%&#8211;30%) and an upper temperature growth limit of 48 &#176;C. …”
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A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer by Brian C. Avanzino, Kirthana Prabhakar, Pranjali Dalvi, Sharon Hartstein, Hannes Kehm, Aarti Balasubramani, Andrew A. Boudreau, Ben Buelow, Karen Chang, Laura M. Davison, Suhasini Iyer, Vidyut Kalwit, Kristin Lewis Wilson, Harbani K. Malik-Chaudhry, Will Pierson, Geovanni Pineda, Udaya S. Rangaswamy, Sowmya Saiganesh, Ute Schellenberger, Harshad S. Ugamraj, Rodolfovan D. Yabut, Roland Buelow, Jocelyn Chapman, Nathan D. Trinklein, Katherine E. Harris

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79 Multiplexed detection of RNA and protein to interrogate the tumor-immune landscape with a novel automated RNAscope™ assay by Anushka Dikshit, Li-Chong Wang, Ge-Ah Kim, Sonali Deshpande, Maithreyan Srinivasan, Julia Yu, Laetitia Chatelain, Nancy George

69 A novel protease-free method for the co-detection of RNA and protein biomarkers using the RNAscope™ technology by Steve Zhou, Li-Chong Wang, Ge-Ah Kim, Sonali Deshpande, Maithreyan Srinivasan, Laetitia Chatelain, Nancy George, Anji Bei

203 Spatial whole transcriptome analysis of differential expression for biomarker discovery in colorectal cancer by Tong Lu, Elim Cheung, Baowen Zhang, Vidyodhaya Sundaram, Lutong Zhang

204 Unveiling differential gene expression profiling and potential biomarker in breast cancer with the NanoString GeoMx digital spatial profiler by Tong Lu, Elim Cheung, Baowen Zhang, Vidyodhaya Sundaram, Jinghao Tian

96 Visualization of protein-protein interactions in the tumor immune microenvironment with a high spatial resolution analysis by Li-Chong Wang, Ge-Ah Kim, Sonali Deshpande, Maithreyan Srinivasan

71 Integration of RNA in situ hybridization and sequential immunofluorescence for same-slide fully automated multi-omics analysis of the tumor microenvironment by Anushka Dikshit, Emerald Doolittle, Ching-Wei Chang, Pino Bordignon, Alexandre Kehren, Alice Comberlato, Arec Manoukian, Paula Juricic, Alix Faillétaz, Rose Delvillar, Steve Zhou, Li-Chong Wang

Biochemical Stability and Microbial Control of Reconstituted DaxibotulinumtoxinA-lanm for Injection by Kimberlee Ellis, Thai Thach, Conor J. Gallagher

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Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review by Shin-ichi Hirano, Yusuke Ichikawa, Yusuke Ichikawa, Bunpei Sato, Bunpei Sato, Yoshiyasu Takefuji, Yoshiyasu Takefuji, Fumitake Satoh, Fumitake Satoh

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1490 High-plex co-detection of RNA and protein to explore tumor-immune interactions utilizing RNAscope with imaging mass cytometry by Anushka Dikshit, James Pemberton, Smriti Kala, Clinton Hupple

Un approccio multisensoriale per imparare a leggere e a scrivere by Mastropasqua, Anna Chiara Angela, Restiglian, Emilia, Tonegato, Pietro

“…This article presents the results of a case study conducted at the Stellar Academy for Dyslexics in Newark (CA), a Californian school where the Slingerland Approach is applied to teaching. …”
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Human GST P1-1 Redesigned for Enhanced Catalytic Activity with the Anticancer Prodrug Telcyta and Improved Thermostability by Aram Ismail, Sridhar Govindarajan, Bengt Mannervik

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Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases by Haru Yamamoto, Yusuke Ichikawa, Shin-ichi Hirano, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh

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Perfluorodioxolane Polymers for Gas Separation Membrane Applications by Yoshiyuki Okamoto, Hao-Chun Chiang, Minfeng Fang, Michele Galizia, Tim Merkel, Milad Yavari, Hien Nguyen, Haiqing Lin

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Molecular Hydrogen as a Novel Antitumor Agent: Possible Mechanisms Underlying Gene Expression by Shin-ichi Hirano, Haru Yamamoto, Yusuke Ichikawa, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh

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A Comprehensive Examination of Severely Ill ME/CFS Patients by Chia-Jung Chang, Li-Yuan Hung, Andreas M. Kogelnik, David Kaufman, Raeka S. Aiyar, Angela M. Chu, Julie Wilhelmy, Peng Li, Linda Tannenbaum, Wenzhong Xiao, Ronald W. Davis

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Follistatin-Like-1 (FSTL1) Is a Fibroblast-Derived Growth Factor That Contributes to Progression of Chronic Kidney Disease by Nicholas A. Maksimowski, Xuewen Song, Eun Hui Bae, Heather Reich, Rohan John, York Pei, James W. Scholey, Nephrotic Syndrome Study Network (NEPTUNE)

“…RNAscope^® (Advanced Cell Diagnostics, Newark CA, USA) localized <i>Fstl1</i> to interstitial cells, and in silico analysis of single cell transcriptomic data from human kidneys showed <i>Fstl1</i> confined to interstitial fibroblasts/myofibroblasts. …”
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Induction EGFR tyrosine kinase inhibitors prior to definitive chemoradiotherapy in unresectable stage III EGFR-mutated non-small cell lung cancer by Jacqueline V. Aredo, Heather A. Wakelee, Angela Bik-Yu Hui, Sukhmani K. Padda, Nitin D. Joshi, H. Henry Guo, Aadel Chaudhuri, Maximilian Diehn, Billy W. Loo, Jr., Joel W. Neal

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Longitudinal changes in 18F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations by Emma S. Luckett, Jolien Schaeverbeke, Steffi De Meyer, Katarzyna Adamczuk, Koen Van Laere, Patrick Dupont, Rik Vandenberghe

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