Linking gas, particulate, and toxic endpoints to air emissions in the Community Regional Atmospheric Chemistry Multiphase Mechanism (CRACMM) by H. O. T. Pye, B. K. Place, B. N. Murphy, K. M. Seltzer, K. M. Seltzer, E. L. D'Ambro, C. Allen, I. R. Piletic, S. Farrell, R. H. Schwantes, M. M. Coggon, E. Saunders, L. Xu, L. Xu, G. Sarwar, W. T. Hutzell, K. M. Foley, G. Pouliot, J. Bash, W. R. Stockwell

“…To support estimation of health risks associated with HAPs, nine species in CRACMM cover 50 % of the total cancer and 60 % of the total non-cancer emission-weighted toxicity estimated for primary HAPs from anthropogenic and biomass burning sources in the US, with the coverage of toxicity higher (<span class="inline-formula"><i>&gt;</i></span> 80 %) when secondary formaldehyde and acrolein are considered. …”
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3506 PRMT5 is a novel therapeutic target to enhance radiation therapy for cancer treatment by Jake L Owens, Elena Beketova, Samantha Tinsley, Andrew Asberry, Xuehong Deng, Chang-Deng Hu

“…Targeting PRMT5 decreases expression of these genes at the protein level and hinders repair of radiation-induced DSBs in multiple cancer and non-cancer cell types. Clinically, PRMT5 expression positively correlates with the expression of these DDR genes across all 43 cancer types analyzed. …”
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Low expression of SLC34A1 is associated with poor prognosis in clear cell renal cell carcinoma by Jiechuan Qiu, Zicheng Wang, Yingkun Xu, Leizuo Zhao, Peizhi Zhang, Han Gao, Qingliang Wang, Qinghua Xia

“…The Wilcoxon rank sum test was used to analyze hub gene levels between paired KIRC and matched non-cancer samples. IHC results were obtained from the HPA online database, and according to the median gene expression level, they were divided into a high-expression group and a low-expression group. …”
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Clinical and radiological characteristics of acute pulmonary embolus in relation to 28-day and 6-month mortality. by Lindsey Norton, Gordon Cooper, Owen Sheerins, Killian Mac A' Bháird, Giles Roditi, Michael Adamson, David Young, Ross Dolan, Colin Church, Adrian Brady, Campbell Tait, Graham McKenzie, Alasdair McFadyen, Matthew Zelic, Donogh Maguire

“…Of these, 20 (8%) patients had died at 28-days and 43 (18%) at 6-months. Of the 197 non-cancer related presentations, 28-day and 6-month mortality were 3% and 8% respectively. …”
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Ameliorating nutritional properties of soybean waste (Okara) through biofermentation using Rhizopus oligosporus by Gupta Sulagna

“…A parallel was simultaneously run on NIH 3T3 cell line, a non-cancer cell line, to check for toxicity. The experiments revealed that 48 hours incubation yields antiproliferative activities on HepG2 cell line in a dose-dependent manner. …”
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A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme by Fliss EM Murtagh, Ping Guo, Alice Firth, Ka Man Yip, Christina Ramsenthaler, Abdel Douiri, Cathryn Pinto, Sophie Pask, Mendwas Dzingina, Joanna M Davies, Suzanne O’Brien, Beth Edwards, Esther I Groeneveld, Mevhibe Hocaoglu, Claudia Bausewein, Irene J Higginson

“…This casemix classification needs broader testing among those with non-cancer conditions, especially those with multiple conditions. …”
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A panel of seven protein tumour markers for effective and affordable multi-cancer early detection by artificial intelligence: a large-scale and multicentre case–control studyResear... by Yi Luan, Guolin Zhong, Shiyong Li, Wei Wu, Xiaoqiang Liu, Dandan Zhu, Yumin Feng, Yixia Zhang, Chaohui Duan, Mao Mao

“…Individuals with no history of cancer were enrolled from the participating sites as the non-cancer group. One tube of peripheral blood was collected from each participant and quantified a panel of seven selected protein tumour markers (PTMs) by a common clinical electrochemiluminescence immunoassay analyser. …”
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Whole‐body and adipose tissue metabolic phenotype in cancer patients by Lindsey J. Anderson, Jonathan Lee, Barbara Anderson, Benjamin Lee, Dorota Migula, Adam Sauer, Nicole Chong, Haiming Liu, Peter C. Wu, Atreya Dash, Yi‐Ping Li, Jose M. Garcia

“…Methods Energy expenditure (EE), plasma, and abdominal subcutaneous WAT were obtained from men (aged 65 ± 8 years) with cancer, with (CWL, n = 27) or without (CWS, n = 47) weight loss, and weight‐stable non‐cancer patients (CON, n = 26). Clinical images were assessed for adipose and muscle area while plasma and WAT were assessed for inflammatory, lipolytic, and browning markers. …”
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Electronic Decision Support for Deprescribing in Patients on Hemodialysis: Clinical Research Protocol for a Prospective, Controlled, Quality Improvement Study by Émilie Bortolussi-Courval, Tiina Podymow, Emilie Trinh, Joseph Moryousef, R. Hanula, Jean-François Huon, Thomas Mavrakanas, Rita Suri, Todd C. Lee, Emily Gibson McDonald

“…On the intervention unit, patients will also receive deprescribing patient empowerment brochures for select medication classes (gabapentinoids, proton-pump inhibitors, sedative hypnotics and opioids for chronic non-cancer pain). Physicians on the intervention unit will be interviewed post-MedRec to determine implementation barriers and facilitators. …”
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Geographical and temporal Understanding In place of Death in England (1984–2010): analysis of trends and associated factors to improve end-of-life Care (GUIDE_Care) – primary resea... by Wei Gao, Yuen K Ho, Julia Verne, Emma Gordon, Irene J Higginson

“…Over the period, the proportion of hospital deaths for people who died from non-cancer increased (57.1–61.2%) and care home deaths reduced (21.2% down to 20.0%); a reverse pattern was seen for those who died of cancer (hospital: reduced, 48.6–47.3%; care home: increased, 9.3–10.1%). …”
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Prognosis of male lung cancer patients with urinary cancer: a study from a national population-based analysis by Wenqiang Li, Mingliang Cheng, Pei Hu, Liang Jiang, Xiaoping Zhao

“…The major cancer-related and non-cancer-related death in the two primaries were lung cancer and heart disease, respectively. …”
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Pollution characteristics and health risk assessment of metals in farmland soil around the largest realgar mining area in Asia by Shuidong FENG, Mengyue CAO, Jun LIU, Yan TANG, Yuke ZENG, Minxue SHEN, Fei YANG

“…The mean non-carcinogenic health risk values of As, Co, Cr, and Pb pollution were greater than 1, and the maximum non-cancer risk value of Sb for children was greater than 1. …”
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The analysis and monitoring of atmospheric volatile organic compounds via thermal desorption gas chromatography mass spectrometry by Wong, Gwendeline Kee Shien

“…Health risk evaluation of non-cancer effects was implemented for 16 compounds, while cancer effects were studied for 5 carcinogenic compounds. …”
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Immediate versus delayed short-term integrated palliative care for advanced long-term neurological conditions: the OPTCARE Neuro RCT by Nilay Hepgul, Rebecca Wilson, Deokhee Yi, Catherine Evans, Sabrina Bajwah, Vincent Crosby, Andrew Wilcock, Fiona Lindsay, Anthony Byrne, Carolyn Young, Karen Groves, Clare Smith, Rachel Burman, K Ray Chaudhuri, Eli Silber, Irene J Higginson, Wei Gao

“…Background: Palliative care is recommended to help meet the needs of patients with progressive non-cancer conditions, such as long-term neurological conditions. …”
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Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden... by Fullman, N, Yearnwood, J, Abay, S, Hay, S, Global Burden of Disease 2016 Healthcare Access and Quality Collaborators

“…To better isolate potential effects of personal health-care access and quality from underlying risk factor patterns, we risk-standardised cause-specific deaths due to non-cancers by location-year, replacing the local joint exposure of environmental and behavioural risks with the global level of exposure. …”

An Ethical Assessment of Fertility Preservation in Pediatric and Adolescent Patients by Shari Esquenazi

“…What happens if the patient ends up getting cancer again and cannot make use of the materials—are they simply destroyed, or are they put to some scientific use? For non-cancer patients, we need to make sure that the trajectory of their illness is on par with undergoing fertility treatment. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…We found the following: A review of education for health and social care professionals is needed to make sure that palliative care for patients with non-cancer conditions such as heart failure is adequately covered. …”
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