Interpretation threshold values for the Oxford Knee Score in patients undergoing unicompartmental knee arthroplasty by Lasse K Harris, Anders Troelsen, Berend Terluin, Kirill Gromov, Andrew Price, Lina H Ingelsrud

“… Background and purpose: Developing meaningful thresholds for the Oxford Knee Score (OKS) advances its clinical use. We determined the minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) values as meaningful thresholds for the OKS at 3-, 12-, and 24-month follow-up in patients undergoing unicompartmental knee arthroplasty (UKA). …”
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Interpretation threshold values for the Oxford Knee Score in patients undergoing unicompartmental knee arthroplasty by Harris, LK, Troelsen, A, Terluin, B, Gromov, K, Price, A, Ingelsrud, LH

“…<strong>Background and purpose: </strong>Developing meaningful thresholds for the Oxford Knee Score (OKS) advances its clinical use. We determined the minimal important change (MIC), patient acceptable symptom state (PASS), and treatment failure (TF) values as meaningful thresholds for the OKS at 3-, 12-, and 24-month follow-up in patients undergoing unicompartmental knee arthroplasty (UKA). …”

Strong Carbon Features and a Red Early Color in the Underluminous Type Ia SN 2022xkq by Jeniveve Pearson, David J. Sand, Peter Lundqvist, Lluís Galbany, Jennifer E. Andrews, K. Azalee Bostroem, Yize Dong, Emily Hoang, Griffin Hosseinzadeh, Daryl Janzen, Jacob E. Jencson, Michael J. Lundquist, Darshana Mehta, Nicolás Meza Retamal, Manisha Shrestha, Stefano Valenti, Samuel Wyatt, Joseph P. Anderson, Chris Ashall, Katie Auchettl, Eddie Baron, Stéphane Blondin, Christopher R. Burns, Yongzhi Cai, Ting-Wan Chen, Laura Chomiuk, David A. Coulter, Dane Cross, Kyle W. Davis, Thomas de Jaeger, James M. DerKacy, Dhvanil D. Desai, Georgios Dimitriadis, Aaron Do, Joseph R. Farah, Ryan J. Foley, Mariusz Gromadzki, Claudia P. Gutiérrez, Joshua Haislip, Jonay I. González Hernández, Jason T. Hinkle, Willem B. Hoogendam, D. Andrew Howell, Peter Hoeflich, Eric Hsiao, Mark E. Huber, Saurabh W. Jha, Cristina Jiménez Palau, Charles D. Kilpatrick, Vladimir Kouprianov, Sahana Kumar, Lindsey A. Kwok, Conor Larison, Natalie LeBaron, Xavier Le Saux, Jing Lu, Curtis McCully, Tycho Mera Evans, Peter Milne, Maryam Modjaz, Nidia Morrell, Tomás E. Müller-Bravo, Megan Newsome, Matt Nicholl, Estefania Padilla Gonzalez, Anna V. Payne, Craig Pellegrino, Kim Phan, Jonathan Pineda-García, Anthony L. Piro, Lara Piscarreta, Abigail Polin, Daniel E. Reichart, César Rojas-Bravo, Stuart D. Ryder, Irene Salmaso, Michaela Schwab, Melissa Shahbandeh, Benjamin J. Shappee, Matthew R. Siebert, Nathan Smith, Jay Strader, Kirsty Taggart, Giacomo Terreran, Samaporn Tinyanont, M. A. Tucker, Giorgio Valerin, D. R. Young

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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Prof. Ali H Mokdad, PhD, Mohammad Hossein Forouzanfar, PhD, Farah Daoud, BS, Charbel El Bcheraoui, PhD, Maziar Moradi-Lakeh, MD, Ibrahim Khalil, MD, Ashkan Afshin, DSc, Marwa Tuffaha, MD, Raghid Charara, MD, Ryan M Barber, BS, Joseph Wagner, BS, Kelly Cercy, BS, Hannah Kravitz, BS, Matthew M Coates, BA, Margaret Robinson, BA, Kara Estep, MPA, Caitlyn Steiner, MPH, Sara Jaber, MD, Ali A Mokdad, MD, Kevin F O'Rourke, MFA, Adrienne Chew, ND, Pauline Kim, BA, Mohamed Magdy Abd El Razek, MBBCh, Safa Abdalla, MD, Prof. Foad Abd-Allah, MD, Jerry P Abraham, MD, Laith J Abu-Raddad, PhD, Niveen M E Abu-Rmeileh, PhD, Abdulwahab A Al-Nehmi, MD, Ali S Akanda, PhD, Hanan Al Ahmadi, DrPH, Mazin J Al Khabouri, PhD, Faris H Al Lami, PhD, Zulfa A Al Rayess, ABFM, Deena Alasfoor, MSc, Fadia S AlBuhairan, MD, Saleh F Aldhahri, MD, Suliman Alghnam, PhD, Samia Alhabib, PhD, Nawal Al-Hamad, PhD, Raghib Ali, FRCP, Syed Danish Ali, BA, Mohammad Alkhateeb, RN, Mohammad A AlMazroa, MD, Mahmoud A Alomari, PhD, Rajaa Al-Raddadi, PhD, Ubai Alsharif, MPH, Nihaya Al-Sheyab, PhD, Shirina Alsowaidi, FRCPC, Mohamed Al-Thani, FRCPCH, Khalid A Altirkawi, MD, Azmeraw T Amare, MPH, Heresh Amini, MSPH, Walid Ammar, PhD, Palwasha Anwari, MD, Hamid Asayesh, PhD, Rana Asghar, MD, Prof. Ali M Assabri, PhD, Reza Assadi, PhD, Umar Bacha, PhM, Alaa Badawi, PhD, Talal Bakfalouni, MD, Mohammed O Basulaiman, PhD, Shahrzad Bazargan-Hejazi, PhD, Neeraj Bedi, MD, Amit R Bhakta, MD, Zulfiqar A Bhutta, PhD, Aref A Bin Abdulhak, MD, Soufiane Boufous, PhD, Rupert R A Bourne, FRCOphth, Hadi Danawi, PhD, Jai Das, MBA, Amare Deribew, PhD, Eric L Ding, ScD, Adnan M Durrani, MD, Yousef Elshrek, PhD, Mohamed E Ibrahim, MPhil, Babak Eshrati, PhD, Alireza Esteghamati, MD, Imad A D Faghmous, MPH, Farshad Farzadfar, MD, Andrea B Feigl, ScD, Seyed-Mohammad Fereshtehnejad, MD, Irina Filip, MD, Florian Fischer, MPH, Fortuné G Gankpé, MD, Ibrahim Ginawi, MD, Melkamu Dedefo Gishu, MS, Rahul Gupta, MD, Rami M Habash, MPH, Nima Hafezi-Nejad, MD, Prof. Randah R Hamadeh, DPhil, Hayet Hamdouni, PhD, Samer Hamidi, PhD, Hilda L Harb, MPH, Mohammad Sadegh Hassanvand, PhD, Mohammad T Hedayati, PhD, Pouria Heydarpour, MD, Prof. Mohamed Hsairi, MD, Abdullatif Husseini, PhD, Nader Jahanmehr, PhD, Prof. Vivekanand Jha, DM, Jost B Jonas, MD, Nadim E Karam, MD, Amir Kasaeian, PhD, Nega Assefa Kassa, PhD, Anil Kaul, MD, Prof. Yousef Khader, ScD, Shams Eldin A Khalifa, MSc, Ejaz A Khan, MPH, Gulfaraz Khan, PhD, Tawfik Khoja, FRCP, Ardeshir Khosravi, PhD, Yohannes Kinfu, PhD, Barthelemy Kuate Defo, PhD, Arjun Lakshmana Balaji, MPH, Raimundas Lunevicius, PhD, Prof. Carla Makhlouf Obermeyer, DSc, Reza Malekzadeh, MD, Morteza Mansourian, PhD, Prof. Wagner Marcenes, PhD, Habibolah Masoudi Farid, MD, Alem Mehari, MD, Abla Mehio-Sibai, PhD, Prof. Ziad A Memish, MD, George A Mensah, MD, Karzan A Mohammad, PhD, Prof. Ziad Nahas, MD, Jamal T Nasher, MSc, Haseeb Nawaz, MD, Prof. Chakib Nejjari, PhD, Muhammad Imran Nisar, MSc, Saad B Omer, PhD, Mahboubeh Parsaeian, PhD, Emmanuel K Peprah, PhD, Aslam Pervaiz, MHA, Farshad Pourmalek, PhD, Prof. Dima M Qato, PhD, Mostafa Qorbani, PhD, Amir Radfar, MD, Anwar Rafay, MS, Kazem Rahimi, DM, Vafa Rahimi-Movaghar, MD, Sajjad Ur Rahman, FRCPCH, Rajesh K Rai, MPH, Prof. Saleem M Rana, PhD, Sowmya R Rao, PhD, Amany H Refaat, PhD, Serge Resnikoff, MD, Gholamreza Roshandel, PhD, Georges Saade, MD, Mohammad Y Saeedi, PhD, Mohammad Ali Sahraian, MD, Shadi Saleh, PhD, Lidia Sanchez-Riera, PhD, Maheswar Satpathy, PhD, Sadaf G Sepanlou, MD, Tesfaye Setegn, MPH, Amira Shaheen, PhD, Saeid Shahraz, PhD, Sara Sheikhbahaei, MD, Kawkab Shishani, PhD, Prof. Karen Sliwa, PhD, Mohammad Tavakkoli, MD, Abdullah S Terkawi, MD, Olalekan A Uthman, PhD, Ronny Westerman, PhD, Mustafa Z Younis, DrPH, Prof. Maysaa El Sayed Zaki, PhD, Faiez Zannad, MD, Gregory A Roth, MD, Haidong Wang, PhD, Prof. Mohsen Naghavi, PhD, Prof. Theo Vos, PhD, Abdullah A Al Rabeeah, MBBS, Prof. Alan D Lopez, PhD, Prof. Christopher J L Murray, DPhil

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Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed by Margaret A. Taub, Matthew P. Conomos, Rebecca Keener, Kruthika R. Iyer, Joshua S. Weinstock, Lisa R. Yanek, John Lane, Tyne W. Miller-Fleming, Jennifer A. Brody, Laura M. Raffield, Caitlin P. McHugh, Deepti Jain, Stephanie M. Gogarten, Cecelia A. Laurie, Ali Keramati, Marios Arvanitis, Albert V. Smith, Benjamin Heavner, Lucas Barwick, Lewis C. Becker, Joshua C. Bis, John Blangero, Eugene R. Bleecker, Esteban G. Burchard, Juan C. Celedón, Yen Pei C. Chang, Brian Custer, Dawood Darbar, Lisa de las Fuentes, Dawn L. DeMeo, Barry I. Freedman, Melanie E. Garrett, Mark T. Gladwin, Susan R. Heckbert, Bertha A. Hidalgo, Marguerite R. Irvin, Talat Islam, W. Craig Johnson, Stefan Kaab, Lenore Launer, Jiwon Lee, Simin Liu, Arden Moscati, Kari E. North, Patricia A. Peyser, Nicholas Rafaels, Christine Seidman, Daniel E. Weeks, Fayun Wen, Marsha M. Wheeler, L. Keoki Williams, Ivana V. Yang, Wei Zhao, Stella Aslibekyan, Paul L. Auer, Donald W. Bowden, Brian E. Cade, Zhanghua Chen, Michael H. Cho, L. Adrienne Cupples, Joanne E. Curran, Michelle Daya, Ranjan Deka, Celeste Eng, Tasha E. Fingerlin, Xiuqing Guo, Lifang Hou, Shih-Jen Hwang, Jill M. Johnsen, Eimear E. Kenny, Albert M. Levin, Chunyu Liu, Ryan L. Minster, Take Naseri, Mehdi Nouraie, Muagututi‘a Sefuiva Reupena, Ester C. Sabino, Jennifer A. Smith, Nicholas L. Smith, Jessica Lasky-Su, James G. Taylor, VI, Marilyn J. Telen, Hemant K. Tiwari, Russell P. Tracy, Marquitta J. White, Yingze Zhang, Kerri L. Wiggins, Scott T. Weiss, Ramachandran S. Vasan, Kent D. Taylor, Moritz F. Sinner, Edwin K. Silverman, M. Benjamin Shoemaker, Wayne H.-H. Sheu, Frank Sciurba, David A. Schwartz, Jerome I. Rotter, Daniel Roden, Susan Redline, Benjamin A. Raby, Bruce M. Psaty, Juan M. Peralta, Nicholette D. Palmer, Sergei Nekhai, Courtney G. Montgomery, Braxton D. Mitchell, Deborah A. Meyers, Stephen T. McGarvey, Angel C.Y. Mak, Ruth J.F. Loos, Rajesh Kumar, Charles Kooperberg, Barbara A. Konkle, Shannon Kelly, Sharon L.R. Kardia, Robert Kaplan, Jiang He, Hongsheng Gui, Frank D. Gilliland, Bruce D. Gelb, Myriam Fornage, Patrick T. Ellinor, Mariza de Andrade, Adolfo Correa, Yii-Der Ida Chen, Eric Boerwinkle, Kathleen C. Barnes, Allison E. Ashley-Koch, Donna K. Arnett, Christine Albert, Cathy C. Laurie, Goncalo Abecasis, Deborah A. Nickerson, James G. Wilson, Stephen S. Rich, Daniel Levy, Ingo Ruczinski, Abraham Aviv, Thomas W. Blackwell, Timothy Thornton, Jeff O’Connell, Nancy J. Cox, James A. Perry, Mary Armanios, Alexis Battle, Nathan Pankratz, Alexander P. Reiner, Rasika A. Mathias

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Associations between preoperative Oxford hip and knee scores and costs and quality of life of patients undergoing primary total joint replacement in the NHS England: an observation... by Eibich, P, Dakin, HA, Price, AJ, Beard, DJ, Arden, NK, Gray, AM

“…In contrast, costs were generally higher for patients with low preoperative OHS/OKS than those with high OHS/OKS. For example, costs of hospital readmissions within 12 months after primary THR/TKR were £740/£888 for patients at the 5th percentile compared with £314/£404 at the 95th percentile of the OHS/OKS distribution.…”

Metabolic equivalent of task scores avoid the ceiling effect observed with conventional patient-reported outcome scores following knee arthroplasty by Arjun Patel, Thomas C. Edwards, Gareth Jones, Alexander D. Liddle, Justin Cobb, Amy Garner

“…The OKS demonstrated a ceiling effect at one year (15.7%) postoperatively. …”
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Optokinetic stimulation effects in the management of unilateral spatial neglect in patients with chronic stroke: study protocol for a randomised controlled trial by Fátima Pérez-Robledo, Juan Luis Sánchez González, Beatriz María Bermejo-Gil, Rocío Llamas-Ramos, Ana María Martín-Nogueras

“…The aim of this study will be to evaluate the OKS effects on the perceptual and postural complications of patients with USN.Methods and analysis Randomised double-blinded clinical trial, with an intervention group that will undergo OKS and a control placebo group. …”
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Development of a patient-reported outcome measure of activity and participation (the OKSAPQ) to supplement the Oxford knee score by Dawson, J, Beard, D, McKibbin, H, Harris, K, Jenkinson, C, Price, A

“…The primary aim of this study was to develop a patient-reported Activity and Participation Questionnaire (the OKS-APQ) to supplement the Oxford knee score, in order to assess higher levels of activity and participation. …”

Which Oxford Knee Score level represents a satisfactory symptom state after undergoing a total knee replacement? by Lina H Ingelsrud, Berend Terluin, Kirill Gromov, Andrew Price, David Beard, Anders Troelsen

“…Background and purpose — Meaningful interpretation of postoperative Oxford Knee Score (OKS) levels is challenging. We established Patient Acceptable Symptoms State (PASS) and Treatment Failure (TF) values for the OKS in patients undergoing primary total knee replacement (TKR) in Denmark. …”
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Does free-living physical activity improve one-year following total knee arthroplasty in patients with osteoarthritis: A prospective study by Bodor Bin sheeha, Malcolm Granat, Anita Williams, David Sands Johnson, Richard Jones

“…OKS was completed at similar follow-up time points. …”
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Outcome-based commissioning of knee arthroplasty in the NHS: system error in a national monitoring programme and the unintended consequences on achieving the Best Practice Tariff by Middleton, R, Wilson, H, Alvand, A, Abram, S, Bottomley, N, Jackson, W, Price, A

“…As a centre that carries out a high volume of unicompartmental knee arthroplasty (UKA), our objectives were: 1) to determine whether the PROMs programme included primary UKA when calculating the gain in Oxford Knee Score (OKS); and 2) to determine the impact of excluding primary UKA on calculated OKS gains for primary knee arthroplasty.…”

The Oxford Knee Score is a reliable predictor of patients in a health state worse than death and awaiting total knee arthroplasty by N. D. Clement, I. Afzal, P. Liu, K. M. Phoon, V. Asopa, D. H. Sochart, D. F. Kader

“…The OKS was the most reliable predictor (area under curve 88.9%, 95% CI 87.8 to 90.1, P < 0.001) of a health state WTD. …”
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Incidence and severity of radiological lateral osteoarthritis 15 years following medial unicompartmental knee arthroplasty by Henry K. C. Searle, Azmi Rahman, Aditya P. Desai, Stephen J. Mellon, David W. Murray

“…Those with severe (mean OKS 35.6 (SD 9.3)) and moderate OA (mean OKS 35.8 (SD 10.5)) tended to have worse outcome scores than those with nil/mild (mean OKS 39.5 (SD 9.2)) but the difference was only significant for OKS-Function (p = 0.044). …”
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Incidence and severity of radiological lateral osteoarthritis 15 years following medial unicompartmental knee arthroplasty by Searle, HKC, Rahman, A, Desai, AP, Mellon, SJ, Murray, DW

“…Those with severe (mean OKS 35.6 (SD 9.3)) and moderate OA (mean OKS 35.8 (SD 10.5)) tended to have worse outcome scores than those with nil/mild (mean OKS 39.5 (SD 9.2)) but the difference was only significant for OKS-Function (p = 0.044).…”

Prism Adaptation and Optokinetic Stimulation Comparison in the Rehabilitation of Unilateral Spatial Neglect by Alessio Facchin, Giusi Figliano, Roberta Daini

“…Optokinetic stimulation (OKS) has also been demonstrated to be effective in ameliorating symptoms of neglect. …”
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What Is the Correlation between Clinical and Radiographic Findings in Patients with Advanced Osteoarthritis of the Knee? by Moritz M. Innmann, Andre Lunz, Larissa Fröhlich, Thomas Bruckner, Christian Merle, Tobias Reiner, Marcus Schiltenwolf

“…Slightly worse results were identified for OKS and pain in patients with K&L grade 4 osteoarthritis compared to patients with K&L grade 3 osteoarthritis (∆OKS 5.5 points, <i>p</i> < 0.001; ∆VAS 1.7 points, <i>p</i> = 0.003). …”
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A matched comparison of the patient-reported outcome measures of 38,716 total and unicompartmental knee replacements: an analysis of linked data from the National Joint Registry of... by Hasan R Mohammad, Andrew Judge, David W Murray

“…A higher proportion of UKRs had an excellent OKS (≥ 41) compared with TKR (47% vs 36%) and a lower proportion of poor OKS (< 27) scores (13% vs. 16%). …”
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Obesity should not be considered a contraindication to medial Oxford UKA: long-term patient-reported outcomes and implant survival in 1000 knees by Molloy, J, Kennedy, J, Jenkins, C, Mellon, S, Dodd, C, Murray, D

“…</p> <h4>Results</h4> <p>All groups had significant improvement in OKS and Tegner scores, with a 4.6 point OKS difference in means at 10 years (p=0.001). …”

A matched comparison of the patient-reported outcome measures of 38,716 total and unicompartmental knee replacements: an analysis of linked data from the National Joint Registry of... by Mohammad, H, Judge, A, Murray, D

“…A higher proportion of UKRs had an excellent OKS (≥ 41) compared with TKR (47% vs 36%) and a lower proportion of poor OKS (< 27) scores (13% vs. 16%). …”