支链、奇数链脂肪酸与肠道健康的关联性研究Association between branched/odd-chain fatty acids and intestinal health by 张颖，张杏芳，闫雨蒙，张颖，沈旖凝，闫媛媛，李晓光 ZHANG Ying, ZHANG Xingfang, YAN Yumeng, ZHANG Ying, SHEN Yining, YAN Yuanyuan, LI Xiaoguang

“…为明确支链脂肪酸（BCFA）与奇数链脂肪酸（OCFA）对肠道健康的影响，利用气相色谱-质谱联用分析健康人群与肠道疾病患者血液中脂肪酸含量的差异，并应用正交偏最小二乘-判别分析（OPLS-DA）鉴定肠道健康人群的特征脂肪酸。结果表明：健康对照组、肠道息肉组、结直肠癌组3组人群中共检测出9种BCFA和4种OCFA；BCFA、OCFA含量在健康人群中显著偏高（p<005），其中anteiso-C17∶ 0、C17∶ 0含量随肠道健康状态恶化呈梯度下降趋势（p<0.05）；OPLS-DA共鉴定出anteiso-C17∶ 0、iso-C17∶ 0、C18∶ 1、C18∶ 0、C16∶ 0、C14∶ 0 6种特征脂肪酸标志物。…”
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Determination of polyphenols in Chinese jujube using ultra-performance liquid chromatography–mass spectrometry by Liu Hongxia, Guo Xiaohua, Wu Jingjie, Liu Hui, Deng Benliang, Zhao Xusheng

“…Different developmental periods could not be clearly distinguished in principal component analysis, and there was a crossover between S2 and S3 stages. In contrast, the OPLS-DA score plot could effectively distinguish between samples of different developmental periods, and its differential metabolites could be visualized by a volcano plot based on OPLS-DA. …”
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Analysis of Aroma Characteristics of Fermented Lingyun Baihao Tea Based on Odor Activity Value by YANG Jingyang, LIANG Guangzhi, LI Ziping, LIANG Xianzhi, CHEN Yuanquan

“…GC-MS analysis and OAV calculation combined with PCA, OPLS-DA and HCA can enable the identification and evaluation of Lingyun Baihao fermented tea aroma. …”
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All-atomic and coarse-grained molecular dynamics investigation of deformation in semi-crystalline lamellar polyethylene by Olsson, Pär A.T., in ’t Veld, Pieter J., Andreasson, Eskil, Bergvall, Erik, Persson Jutemar, Elin, Petersson, Viktor, Rutledge, Gregory C., Kroon, Martin

“…To this end, specifically the all-atomic optimized potential for liquid simulations (OPLS-AA) and the coarse-grained united-atom (UA) force-fields are used to simulate the yielding and tensile behaviour for the lamellar separation mode. …”
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Novel Grade Classification Tool with Lipidomics for Indica Rice Eating Quality Evaluation by Luyao Zhao, Xiaoliang Duan, Hongbin Liu

“…Random forest (RF) results further verified the OPLS-DA model, and the accuracy of this method for grade prediction was 90.20%. …”
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Immunostimulant Compounds Identification in Indonesian Underutilized Zingiberaceae Spices by Dian Rosalina, Nancy Dewi Yuliana, Ririn Anggraeni, Endang Prangdimurti

“…A. malaccensis was chosen for the next step. The results of OPLS analysis showed that the retention time interval which strongly correlated with the immunostimulant activity was 27.0 – 28.5 minutes, which were abundant in methanol fraction. …”
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Pomegranate fruit juice adulteration with apple juice: detection by UV–visible spectroscopy combined with multivariate statistical analysis by Lucia Pappalardo

“…Unsupervised principle component analysis (PCA), supervised projection to latent structure discriminant analysis (PLS-DA) and orthogonal projection to latent structure discriminant analysis (OPLS-DA) were performed on the full spectra. OPLS-DA analysis of UV–visible spectra proved to be a suitable method to detect pomegranate juices adulterated by more than 20% v/v apple juice concentrate.…”
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Diagnosis Of Dengue Infection Using Metabolome Analysis (Biomarkers Profiling) by Noor, Nurul Shahfiza

“…Two types of pattern recognitions were employed, namely, Principle Component Analysis (PCA) and Orthogonal Partial Least SquareDiscriminant Analysis (OPLS-DA). NMR signals which highlighted in the OPLS-DA S-plot were further selected and identified using Human Metabolome Database (HMDB), Chenornx Profiler and from published literature.…”
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Comparison of Caffeoylquinic Acids and Functional Properties of Domestic Sweet Potato (<i>Ipomoea batatas</i> (L.) Lam.) Storage Roots with Established Overseas Varieties by Charmaine J. Phahlane, Sunette M. Laurie, Tinotenda Shoko, Vimbainashe E. Manhivi, Dharini Sivakumar

“…In the OPLS-DA scatter plot, one cluster, which included Peruvian variety ‘199062.1’, was separated from the others. …”
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Towards objective measurements of habitual dietary intake patterns: comparing NMR metabolomics and food frequency questionnaire data in a population-based cohort by Anna Winkvist, Ingegerd Johansson, Lars Ellegård, Helen M Lindqvist

“…Results Age, sex, body mass index, education and year of study participation had significant influence on OPLS metabolite models. OPLS models for healthful PDI and LCA-clusters were not significant, whereas for HDS, rMDS, PDI and unhealthful PDI significant models were obtained (CV-ANOVA p < 0.001). …”
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¹H NMR Combined with Multivariate Statistics for Discrimination of Female and Male Flower Buds of <i>Populus tomentosa</i> by Bo Xu, Cui Wu, Zhuojun Li, Pingping Song, Zhimao Chao

“…The two groups were also well discriminated with OPLS-DA (R²X, 0.808; R²Y, 0.976; Q², 0.960). …”
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Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study. by Evagelia C Laiakis, Gerard A J Morris, Albert J Fornace, Stephen R C Howie

“…'Unsupervised' (blinded) data were analyzed by Principal Component Analysis (PCA), while 'supervised' (unblinded) analysis was by Partial Least Squares-Discriminant Analysis (PLS-DA) and Orthogonal Projection to Latent Structures (OPLS). Potential markers were extracted from S-plots constructed following analysis with OPLS, and markers were chosen based on their contribution to the variation and correlation within the data set. …”
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Nuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury. by François Jouret, Justine Leenders, Laurence Poma, Jean-Olivier Defraigne, Jean-Marie Krzesinski, Pascal de Tullio

“…Statistical discriminant analyses, i.e. principal component analysis and orthogonal projections to latent structures (OPLS-DA), were performed on urine, serum and kidney lysates at each time-point. …”
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Structural, Microstructural, Elastic, and Microplastic Properties of Aluminum Wires (from AAAC (A50) Cables) after Fatigue Tests by Aleksandr A. Levin, Maria V. Narykova, Alexey I. Lihachev, Boris K. Kardashev, Andrej G. Kadomtsev, Andrei G. Panfilov, Nikita D. Prasolov, Roman V. Sokolov, Pavel N. Brunkov, Makhsud M. Sultanov, Alexander V. Strizhichenko, Ilia A. Boldyrev

“…Single Al wires from unused AAAC (A50) cables were studied after laboratory fatigue testing, which simulated processes arising in these wires during their operation in the cables of overhead power lines (OPLs) and are valuable for predicting the lifespan of cables of OPLs. …”
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Unravelling the metabolomic diversity of pigmented and non-pigmented traditional rice from Tamil Nadu, India by Venkatesan Subramanian, Udhaya Nandhini Dhandayuthapani, Senthilraja Kandasamy, Jidhu Vaishnavi Sivaprakasam, Prabha Balasubramaniam, Mohan Kumar Shanmugam, Sriram Nagappan, Subramanian Elangovan, Umesh Kanna Subramani, Kumaresan Palaniyappan, Geethalakshmi Vellingiri, Raveendran Muthurajan

“…The metabolite profiles were subjected to data mining processes, including principal component analysis (PCA), Orthogonal Partial Least Square Discrimination Analysis (OPLS-DA) and Heat map analysis. OPLS-DA identified 144 differential metabolites between the 2 rice groups, variable importance in projection (VIP) ≥ 1 and fold change (FC) ≥ 2 or FC ≤ 0.5. …”
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Urinary proteome profiles associated with cognitive decline in community elderly residents—A pilot study by Yumi Watanabe, Yoshitoshi Hirao, Kensaku Kasuga, Kaori Kitamura, Kazutoshi Nakamura, Tadashi Yamamoto

“…Urinary proteomics using mass spectrometry was performed and discriminant models were created using orthogonal partial least squares-discriminant analysis (OPLS-DA). OPLS-DA yielded two models that significantly discriminated between the two groups at baseline and follow-up. …”
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Impact of oral precancerous lesions on oral cancer development in patients with oral lichen planus: a retrospective cohort study of 318 oral lichen planus patients by Yu-Cheng Chu, Pei-Yu Lin, Wan-Ting Huang, Hsun-Yu Huang, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen

“…Further research is needed to elucidate the underlying molecular mechanisms linking OLP, OPL, and oral cancer occurrence.…”
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Identifikasi Komponen Aktif Jahe Merah (Zingiber officinale Roscoe var. Rubrum) sebagai Sumber Antioksidan dengan Pendekatan Metabolomik Berbasis HPLC by Diny Agustini Sandrasari, Nuri Andarwulan, Didah Nur Faridah, Fitriya Nur Annisa Dewi

“…Profil senyawa kimia dari ekstrak dan fraksi (heksana, kloroform, etil asetat, dan air) dianalisis menggunakan High Performance Liquid Chromatography (HPLC) yang dilanjutkan dengan analisis metabolomik Orthogonal Projection to Latent Structure (OPLS). Hasil uji metabolomik OPLS diperoleh fraksi etil asetat sebagai sampel yang paling berkontribusi terhadap aktivitas antioksidan. …”
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Preliminary study on the geographical origin of Chinese 'Cuiguan' pears using integrated stable isotope and multi-element analyses by Tingting Zeng, Tingting Fu, Yongchuan Huang, Wei Zhang, Jiuping Gong, Bingjing Ji, Xiaoxia Yang, Mingfeng Tang

“…OPLS-DA achieved pear origin accuracy rates of 87.76 % by combining stable isotope ratios and elemental contents. …”
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Global metabolomics study on the pathogenesis of pediatric medulloblastoma via UPLC- Q/E-MS/MS. by Zhehao Huang, Xianglan Li, Bo Wei, Yin Yu

“…Principal component analysis and orthogonal projections to latent structures discriminant analysis (OPLS-DA) intuitively revealed the significantly distinct metabolic profiles between medulloblastoma and HC (p < 0.01 for permutation test on OPLS-DA model). …”
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