Adult-Onset ANCA-Associated Vasculitis in SAVI: Extension of the Phenotypic Spectrum, Case Report and Review of the Literature by Frederik Staels, Frederik Staels, Albrecht Betrains, Peter Doubel, Mathijs Willemsen, Mathijs Willemsen, Vincent Cleemput, Steven Vanderschueren, Anniek Corveleyn, Isabelle Meyts, Ben Sprangers, Yanick J. Crow, Yanick J. Crow, Stephanie Humblet-Baron, Adrian Liston, Adrian Liston, Rik Schrijvers, Rik Schrijvers

“…However, since its description a wider spectrum of associated manifestations and disease-onset has been observed. We report a kindred with a heterozygous STING mutation (p.V155M) in which the 19-year-old proband suffered from isolated adult-onset ANCA-associated vasculitis. …”
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Rapid keratitis and perforation after corneal collagen cross-linking by Matthew Schear, Ashwinee Ragam, John Seedor, Ira Udell, Carolyn Shih

“…Purpose: To describe a case of rapid keratitis and corneal perforation after epithelium off collagen cross-linking. Observations: We report a case of a 17-year-old male who underwent collagen cross-linking with the protocol and device approved by the United States Food and Drug Administration (FDA) that developed a corneal infiltrate 3 days after the procedure. …”
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Aerial drone misadventure: A novel case of trauma resulting in ocular globe rupture by Eliza E. Moskowitz, Yonaton M. Siegel-Richman, George Hertner, Thomas Schroeppel

“…Purpose: The purpose of this case report is to present the novel findings of a drone causing such a traumatic ocular injury and provide recommendations for how it might be prevented. Observations: We report on a recent case where a child presented to our Emergency Department after incurring a blow to the face by the propeller of a remote controlled drone. …”
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Conjunctival leiomyosarcoma by Aluisio Rosa Gameiro Filho, Ana Marisa Pires Castello Branco, Moacyr Pezati Rigueiro, Melina Correia Morales, Rubens N. Belfort

“…However, it rarely affects the eye, and when it does, it is usually located in the orbit, being extremely rare in the conjunctiva. Observations: We report a case of a 45 years old male patient, with a recurrent rapid growing conjunctival mass on the temporal limbus of his left eye, which was excised, and the anatomopathological report was suggestive of a grade 1 leiomyosarcoma. …”
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Unexpected Adverse Events of Immune Checkpoint Inhibitors by Walid Shalata, Alexander Yakobson, Aharon Y. Cohen, Iris Goldstein, Omar Abu Saleh, Yulia Dudnik, Keren Rouvinov

“…However, the utilization of these groundbreaking therapies has led to the observation and reporting of various types of adverse events, commonly known as immune-related adverse events (irAEs). …”
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Treatment and secondary prophylaxis of venous thromboembolism with direct oral anticoagulants in patients with severe hereditary thrombophilia by Pasquale Madonna, Anna Guida, Maria Gabriella Coppola, Paolo Tirelli, Ernesto Grasso

“…During the follow-up, neither recurrences of VTE nor hemorrhagic episodes were observed. This report describes the efficacy and safety of therapy with anti-Xa in the treatment and secondary prophylaxis of VTE in patients with SHT.…”
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Lockdown-related idiopathic facial paralysis: illustration of an indirect victim of the COVID-19 pandemic? by Fricain Margaux, Moreau Nathan

“…Unfortunately, there seems to be little focus on indirect victims of COVID-19, such as diseases/ailments secondary to COVID-19-related lockdown in relevant countries. Observation: We report a case of idiopathic facial paralysis (Bell's Palsy) that occurred in an otherwise-healthy 49-year-old French chef during nationwide lockdown, possibly fostered by severe concerns regarding his professional prospects. …”
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Observations of lion roars in the magnetosheath by the STAFF/DWP experiment on the Double Star TC-1 spacecraft by K. H. Yearby, H. S. C. Alleyne, N. Cornilleau-Wehrlin, O. Santolik, O. Santolik, M. A. Balikhin, S. N. Walker, A. Fazakerley, A. Lahiff

“…The characteristics of lion roars observed are reported. The maximum lion roar intensities appear higher than reported by most previous studies. …”
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Ureteral tumor in an ectopic duplex system: a case report by Omar Karray, Hassen Khouni, Mahdi Charfi, Rami Boulma, Mehdi Debaibi, Rym Makhlouf, Karim Bargaoui, Oumeima Nessej, Azza Seridi, Slim Fourti, Mohamed Habib Bouhaouala, Adnene Chouchene

“…Carcinologic surgery must consider the anatomic variant, mainly related to the ectopic site of the ureteral orifice. Observation We report a case of a ureteral urothelial carcinoma in a North African 52-year-old male patient, in a right duplex system. …”
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Charting the solar cycle by S. C. Chapman, S. C. Chapman

“…We propose a method-charting-that can be used to combine observations, and reports of societal impacts, to improve our understanding of space weather risk.…”
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On the interplay between pain observation, guilt and shame proneness and honesty by Panagiotis Mitkidis, Thaler Hanna, Perkovic Sonja, Ayal Shahar, Karg Simon, Ariely Dan

“…In two laboratory experiments, we examined the interplay between pain observation, self-reported guilt and shame, subjective perceptions of pain intensity, and subsequent honest behavior. …”
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Are Glucosylceramide-Related Sphingolipids Involved in the Increased Risk for Cancer in Gaucher Disease Patients? Review and Hypotheses by Patricia Dubot, Leonardo Astudillo, Nicole Therville, Frédérique Sabourdy, Jérôme Stirnemann, Thierry Levade, Nathalie Andrieu-Abadie

“…In this chapter, we first review published and personal clinical observations that report on the increased risk of developing cancers in patients affected with Gaucher disease, an inborn disorder characterized by defective lysosomal degradation of β-glucosylceramide. …”
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Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection by Monica P. Gonzalez, Radames Rios, Mariella Pappaterra, Miguel Hernandez, Allison Toledo, Carmen Santos, Andres Emanuelli, Shree K. Kurup, Armando L. Oliver

“…To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection. Methods. Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. …”
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Short-term fate of rehabilitated orphan black bears released in New Hampshire by Wesley E. Smith, Peter J. Pekins, Andrew A. Timmins, Benjamin Kilham

“…Bears released in 2011 had higher apparent survival and were not observed or reported in any nuisance behavior, whereas no bears released in 2012 survived, and all were involved in minor nuisance behavior. …”
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Modelling the Proton-Conductive Membrane in Practical Polymer Electrolyte Membrane Fuel Cell (PEMFC) Simulation: A Review by Edmund J. F. Dickinson, Graham Smith

“…Theoretical models used to describe the proton-conductive membrane in polymer electrolyte membrane fuel cells (PEMFCs) are reviewed, within the specific context of practical, physicochemical simulations of PEMFC device-scale performance and macroscopically observable behaviour. Reported models and their parameterisation (especially for Nafion 1100 materials) are compiled into a single source with consistent notation. …”
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A case of non-arteritic anterior ischemic optic neuropathy after completion of Harvoni therapy by Niranjan Manoharan, MD, Prem Sagar Subramanian, MD, PhD

“…Purpose: To report the first reported case of non-arteritic anterior ischemic optic neuropathy (NAION) associated with the use of Harvoni (Gilead Sciences, Foster City, CA, USA), a newly approved treatment for Hepatitis C. Observations: We report a case of NAION in a hepatitis C patient who completed Harvoni therapy just prior to presentation. …”
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Bilateral cystoid macular edema misdiagnosed as pars planitis in a patient on sertraline therapy by Aniruddha Agarwal, Kanika Aggarwal, Aman Kumar, Vishali Gupta

“…Purpose: To describe the presentation, clinical course and management of a patient with bilateral maculopathy associated with sertraline. Observations: We report a rare case of bilateral cystoid macular edema and subretinal fluid in a 78-year-old Asian Indian female who was on chronic sertraline therapy. …”
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EVALUASI PENGELOLAAN OBAT TAHAP SELEKSI DAN PERENCANAAN DI ERA JAMINAN KESEHATAN NASIONAL DI RSUD H. HASAN BASERY KANDANGAN TAHUN 2014 by Mochammad Maulidie Alfiannor Saputera

“…This study design was descriptive exploratory retrospective nature. Observations retrospective report covers the planning and the use of drugs, financial statements, reports of drug procurement, invoicing, stock taking report. …”
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Observation of the Production of Three Massive Gauge Bosons at √ s = 13 TeV

“…© 2020 CERN. The first observation is reported of the combined production of three massive gauge bosons (VVV with V=W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV. …”
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Observation of the Production of Three Massive Gauge Bosons at √ s = 13 TeV by The CMS Collaboration, Abercrombie, Daniel Robert, Allen, Branden, Bi, Ran, Brandt, Stephanie Akemi, Busza, Wit, Cali, Ivan Amos, Chen, Y., D'Alfonso, Mariarosaria, Gomez-Ceballos, Guillelmo, Goncharov, Maxim, Harris, Philip Coleman, Hsu, David, Hu, Miao, Klute, Markus, Kovalskyi, Dmytro, Krupa, Jeffrey, Lee, Y.-J., Luckey Jr, P David, Maier, Benedikt, Marini, Andrea Carlo, McGinn, Christopher Francis, Mironov, Camelia Maria, Narayanan, S., Niu, Xinmei, Paus, Christoph M. E., Rankin, Dylan S., Roland, Christof E, Roland, Gunther M, Shi, Z., Stephans, George S. F., Sumorok, Konstanty C, Tatar, Kaya, Velicanu, Dragos Alexandru, Wang, J., Wang, T.W., Wang, Z., Wyslouch, Boleslaw

“…© 2020 CERN. The first observation is reported of the combined production of three massive gauge bosons (VVV with V=W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV. …”
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