Systematic Review on the Therapeutic Options for COVID-19: Clinical Evidence of Drug Efficacy and Implications by Abubakar AR, Sani IH, Godman B, Kumar S, Islam S, Jahan I, Haque M

“…However, retrospective observational studies reported the efficacy of remdesivir and lopinavir/ritonavir in reducing viral load, although there have been concerns with lopinavir/ritonavir and, more recently, remdesivir. …”
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Hate speech in adolescents: A binational study on prevalence and demographic differences by Melisa Castellanos, Alexander Wettstein, Sebastian Wachs, Sebastian Wachs, Julia Kansok-Dusche, Cindy Ballaschk, Norman Krause, Ludwig Bilz

“…Significant differences by country, gender, and migration background were observed. Girls reported more offline victimization experiences, less perpetration, and a greater frequency of witnessing hate speech. …”
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Using cloud-based mobile technology for assessment of competencies among medical students by Gary S. Ferenchick, David Solomon

“…A majority of observers (92%) reported satisfaction with the CEX. Inter-rater reliability was measured at 0.69 among all observers viewing the videotapes and these ratings adequately discriminated competent from non-competent performance. …”
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Beneficial Role of Blood Flow Restriction Exercise in Heart Disease and Heart Failure Using the Muscle Hypothesis of Chronic Heart Failure and a Growing Literature by Lawrence P. Cahalin, Magno F. Formiga, Johnny Owens, Brady Anderson, Luke Hughes

“…A substantial literature of BFRE in older adults exists in which significant gains in strength and functional performance have been observed without report of adverse events. Research examining the effects of BFRE in heart disease (HD) and heart failure (HF) appears to be increasing for which reason the Muscle Hypothesis of Chronic Heart Failure (MHCHF) will be used to fully elucidate the effects BFRE may have in patients with HD and HF highlighted in the MHCHF.Methods: A comprehensive literature review was performed in PubMed and the Cochrane library through February 2022. …”
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Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…<h4>Methods and findings</h4>We searched Embase, MEDLINE, Global Health, Web of Science, and grey literature from inception until December 20, 2023, for observational studies reporting aetiologic diagnoses among symptomatic populations in SSA. …”
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Meta‐analysis of the demographic and prognostic significance of gastrointestinal symptoms in COVID‐19 patients by Shafquat Zaman, Shahin Hajibandeh, Shahab Hajibandeh, Ali Yasen Y Mohamedahmed, Mohammed E El‐Asrag, Nabil Quraishi, Tariq H Iqbal, Andrew D Beggs

“…Results Twenty‐four comparative observational studies reporting a total of 51 522 COVID‐19 patients with (n = 6544) or without (n = 44 978) GI symptoms were identified. …”
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The dynamics of inflammatory markers in coronavirus disease-2019 (COVID-19) patients: A systematic review and meta-analysis by Roshan Kumar Mahat, Suchismita Panda, Vedika Rathore, Sharmistha Swain, Lalendra Yadav, Sumesh Prasad Sah

“…Methods: A comprehensive systematic literature search of medical electronic databases including Pubmed/Medline, Europe PMC, and Google Scholar was performed for relevant data published from January 1, 2020 to June 26, 2020. Observational studies reporting clear extractable data on inflammatory parameters in laboratory-confirmed COVID-19 patients were included. …”
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Global prevalence and risk factors of fatigue and post-infectious fatigue among patients with dengue: a systematic review and meta-analysisResearch in context by Nuzul Sri Hertanti, Trung V. Nguyen, Yeu-Hui Chuang

“…We searched PubMed, Ovid MEDLINE, Web of Science, Embase, and CINAHL from their inception to June 22, 2024. Observational studies reporting the prevalence of fatigue or PIF among dengue patients were included. …”
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Virtual reality simulation and real-life training programs for cataract surgery: a scoping review of the literature by Lea Dormegny, Van Charles Lansingh, Anne Lejay, Nabil Chakfe, Rémi Yaici, Arnaud Sauer, David Gaucher, Bonnie An Henderson, Ann Sofia Skou Thomsen, Tristan Bourcier

“…All three supervised surgery studies were observational and reported a high amount of cataract surgeries performed by trainees. …”
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A Real-World Effectiveness Study Using a Mobile Application to Evaluate Early Outcomes with Upadacitinib in Rheumatoid Arthritis by Leslie R. Harrold, Patrick Zueger, W. Benjamin Nowell, Taylor Blachley, Amy Schrader, Paul R. Lakin, David Curtis, Laura Stradford, Shilpa Venkatachalam, Namita Tundia, Pankaj A. Patel

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Development of predictive models for lymphedema by using blood tests and therapy data by Xuan-Tung Trinh, Pham Ngoc Chien, Nguyen-Van Long, Le Thi Van Anh, Nguyen Ngan Giang, Sun-Young Nam, Yujin Myung

“…In current machine learning models for lymphedema prediction, reliance on observable symptoms reported by patients introduces the possibility of errors in patient-input data. …”
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High Metallicity and Non-Equilibrium Chemistry in the Dayside Atmosphere of Hot-Neptune Gj 436b by Madhusudhan, Nikku, Seager, Sara

“…We present a detailed analysis of the dayside atmosphere of the hot-Neptune GJ 436b, based on recent Spitzer observations. We report statistical constraints on the thermal and chemical properties of the planetary atmosphere, study correlations between the various molecular species, and discuss scenarios of equilibrium and non-equilibrium chemistry in GJ 436b. …”
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Bifurcations and symmetries in viscous flow by Kobine, J

“…A low-dimensional bifurcation structure is uncovered which connects the two modes in parameter space, and involves a novel type of steady single-cell flow. Finally, observations are reported of a nontrivial type of dynamical behaviour which bears strong resemblance to motion found in a circularly symmetric Taylor-Couette system that is related to the Šilnikov mechanism for finite-dimensional chaos.…”

Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. by Mathers, J, Movahedi, M, Macrae, F, Mecklin, J, Moeslein, G, Olschwang, S, Eccles, D, Evans, G, Maher, E, Bertario, L, Bisgaard, M, Dunlop, M, Ho, J, Hodgson, S, Lindblom, A, Lubinski, J, Morrison, P, Murday, V, Ramesar, R, Side, L, Scott, R, Thomas, H, Vasen, H, Gerdes, A, Barker, G

“…BACKGROUND: Observational studies report that higher intake of dietary fibre (a heterogeneous mix including non-starch polysaccharides and resistant starches) is associated with reduced risk of colorectal cancer, but no randomised trials with prevention of colorectal cancer as a primary endpoint have been done. …”

Types and concentrations of blood-based biomarkers in adults with peripheral neuropathies: a systematic review and meta-analysis by Fundaun, J, Kolski, M, Molina-Álvarez, M, Baskozos, G, Schmid, AB

“…<br><br> <strong>Study Selection</strong> Observational studies reporting on blood biomarkers in patients diagnosed with peripheral neuropathy were included. …”

Adverse health events associated with antipsychotic use: an umbrella review by Chow, RTS

“…The included meta-analyses of RCTs and observational studies reported statistically significant effect sizes for 26 adverse outcomes. …”

Co-occurrence of chronic traumatic encephalopathy and prion disease by Satish Kumar Nemani, Silvio Notari, Ignazio Cali, Victor E Alvarez, Diane Kofskey, Mark Cohen, Robert A. Stern, Brian Appleby, Joseph Abrams, Lawrence Schonberger, Ann McKee, Pierluigi Gambetti

“…However, the coexistence of prion disease in CTE has not been observed. We report three cases of histopathologically validated CTE with co-existing sporadic prion disease. …”
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Prevalence of meropenem-resistant Pseudomonas Aeruginosa in Ethiopia: a systematic review and meta‑analysis by Mengistie Yirsaw Gobezie, Minimize Hassen, Nuhamin Alemayehu Tesfaye, Tewodros Solomon, Mulat Belete Demessie, Tesfaye Dessale Kassa, Teklehaimanot Fentie Wendie, Abel Andualem, Ermiyas Alemayehu, Yaschilal Muche Belayneh

“…Inclusion criteria encompassed observational studies reporting the prevalence of meropenem-resistant P. aeruginosa in Ethiopia. …”
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Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review by Rob A. van de Graaf, Rob A. van de Graaf, Vicky Chalos, Vicky Chalos, Vicky Chalos, Gregory J. del Zoppo, Gregory J. del Zoppo, Aad van der Lugt, Diederik W. J. Dippel, Bob Roozenbeek, Bob Roozenbeek

“…Both studies reporting relative effects of heparin on functional independence found it to increase this chance.ConclusionRandomized controlled trials investigating the effect of periprocedural antithrombotic treatment in MT are lacking. Some observational studies report a slight increase in sICH risk, which may be acceptable because they also suggest a beneficial effect on functional outcome. …”
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Serotonin and the ventilatory effects of etonogestrel, a gonane progestin, in a murine model of congenital central hypoventilation syndrome by Alexis Casciato, Lola Bianchi, Manon Reverdy, Fanny Joubert, Roman Delucenay-Clarke, Sandrine Parrot, Nélina Ramanantsoa, Eléonore Sizun, Boris Matrot, Christian Straus, Thomas Similowski, Florence Cayetanot, Laurence Bodineau

“…No pharmacological treatment is available. Clinical observations have reported non-systematic CO2/H+ chemosensitivity recovery under desogestrel.MethodsHere, we used a preclinical model of Congenital Central Hypoventilation Syndrome, the retrotrapezoid nucleus conditional Phox2b mutant mouse, to investigate whether etonogestrel, the active metabolite of desogestrel, led to a restoration of chemosensitivity by acting on serotonin neurons known to be sensitive to etonogestrel, or retrotrapezoid nucleus PHOX2B residual cells that persist despite the mutation. …”
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