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NMR structure and activity relationship of defensin-analogous peptides
Published 2014“…For peptoids targeting Gram-positive bacteria, large oligomers formed by strong hydrophobic interactions between xanthone groups were observed in aqueous solution, lipid micelles and liposomes. …”
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Thesis -
22
Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease
Published 2025“…Experiments have revealed that amyloid beta oligomers induce microvascular mural cells to contract, thereby constricting capillaries and increasing resistance to blood flow. …”
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23
Electronic structure and optical properties of conjugated molecules : SAC-CI study
Published 2013“…Electronic structure and optical properties of some organic conjugated molecules, that is the oligomers for organic-light emitting diodes (OLED), chelating hetero-atomic conjugated ligands, and UVB blocking molecules, have been investigated by the SAC-CI method. …”
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Conference Paper -
24
Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes
Published 2024“…Here, we profile 5-methylcytosine (5mC)-oxidising Ten-Eleven Translocation (TET) enzymes using MS and 1H NMR spectroscopy methods and reveal a high degree of substrate oxidation-independent 2OG turnover under a range of conditions. 2OG decarboxylase activity is substantial (>20% 2OG turned over after 1 h) in the absence of substrate, while, under substrate-saturating conditions, half of total 2OG consumption is uncoupled from substrate oxidation. 2OG kinetics are affected by substrate and non-substrate DNA oligomers, and the sequence-agnostic effects are observed in amoeboflagellate Naegleria gruberi NgTet1 and human TET2. …”
Journal article -
25
Characterizing the Impact of Oligomerization on Redox Flow Cell Performance
Published 2024“…Redox flow batteries (RFBs) are hindered by complex failure modes, particularly crossover through the membrane, resulting in capacity fade and reduced cycling efficiencies. Redox‐active oligomers (RAOs) have recently been proposed for mitigating this phenomenon while maintaining sufficient transport properties; however, to date, few studies have quantified how the chemical and electrochemical properties of RAOs influence their performance in redox flow cells. …”
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Article -
26
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Published 2025“…Its liquid condensation likely involves the formation of higher-order oligomers that phase separate in a manner dependent on the protein’s N-terminal CAP-Gly domain and C-terminal EEY/F-like motif. …”
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27
Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids
Published 2017“…RNA triplex structures play vital roles in regulating various biological processes, and have attracted a Jot of interest in designing TFOs (triplex-fonning oligomers) that could selectively and specifically bind to the nuclei acid duplex. …”
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Thesis -
28
Viroporin activity of the foot-and-mouth disease virus non-structural 2B protein
Published 2015“…The 2B protein monomers interacted with each other to form both intracellular and extracellular oligomers. The Ca2+ concentration in the cells increased, and the integrity of the cytoplasmic membrane was disrupted in cells that expressed the 2B protein. …”
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Journal Article -
29
Mechanics and manufacturing of crosslinked cellulose nanocomposites
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Thesis -
30
Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol
Published 2024“…Results from mouse models of Alzheimer’s disease have shown beneficial effects of rapamycin, including preventing or reversing cognitive deficits, reducing amyloid oligomers and tauopathies and normalizing synaptic plasticity and cerebral glucose uptake. …”
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31
Development of interpenetrating network (IPN) hybrid composite for thin film protection
Published 2013“…In this study, TMPTA, TMPT(EO)A, PEGDA, TPGDA, CN8003, CN104 and Epolam® 5015 were used in the investigation of the formation of simultaneous IPNs with TMPT(EO)A, PEGDA and TPGDA as the most reactive monomers among the seven monomers and oligomers. The effects of composition of individual monomers and temperature were investigated under optimum photoinitiator concentration. …”
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Thesis -
32
Studies on the Chitin Binding Property of Novel Cysteine-Rich Peptides from Alternanthera sessilis
Published 2016“…This indicates that the biosynthesis of altides is through the secretory pathway. (1)H NMR titration experiments showed that the 29-30-amino acid altides bind to chitin oligomers with dissociation constants in the micromolar range. …”
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Journal Article -
33
Synthesis and characterization UV-curable waterborne polyurethane acrylate/Al2O3 nanocomposite coatings derived from Jatropha oil polyol
Published 2022“…The UV-WPUA/Al2O3 coatings were obtained with 75 wt% oligomers, 25 wt% monomer trimethylolpropane triacrylate (TMPTA), and 3 wt% of a commercial photoinitiator (benzhophenol) for UV-curing were used. …”
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34
Integrative and comparative analysis of coiled-coil based marine snail egg cases : a model for biomimetic elastomers
Published 2014“…Despite these differences, mixtures of denatured native egg case proteins readily re-folded in citrate–phosphate assembly buffer into α-helix rich, coiled-coil based oligomers, as determined by attenuated total reflection Fourier transform infrared spectroscopy, circular dichroism and MALDI-TOF. …”
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Journal Article -
35
Spatial and subcellular gene expression patterns in myogenic differentiation and muscle pathology
Published 2024“…Promising dystrophin-restoration therapies such as gene editing using the CRISPR-Cas9 system and antisense oligonucleotide-mediated exon skipping using peptide-phosphorodiamidate morpholino oligomers (PPMOs) are currently in development. The efficacy of these approaches is typically assessed in terms of the amount of dystrophin restored, while correct sarcolemmal localisation of the protein has largely been assumed.…”
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36
Synthesis of heavy cyanide analogs for the design of novel Prussian blue analogs
Published 2023“…The synthesis, characterization, and bonding of the oligomers and their monomer precursors are discussed herein. …”
Thesis