Comparative survival analysis of multiparametric tests—when molecular tests disagree—A TEAM Pathology study by John M. S. Bartlett, Jane Bayani, Elizabeth Kornaga, Keying Xu, Greg R. Pond, Tammy Piper, Elizabeth Mallon, Cindy Q. Yao, Paul C. Boutros, Annette Hasenburg, J. A. Dunn, Christos Markopoulos, Luc Dirix, Caroline Seynaeve, Cornelis J. H. van de Velde, Robert C. Stein, Daniel Rea

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Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer by Stanley Zhou, James R. Hawley, Fraser Soares, Giacomo Grillo, Mona Teng, Seyed Ali Madani Tonekaboni, Junjie Tony Hua, Ken J. Kron, Parisa Mazrooei, Musaddeque Ahmed, Christopher Arlidge, Hwa Young Yun, Julie Livingstone, Vincent Huang, Takafumi N. Yamaguchi, Shadrielle M. G. Espiritu, Yanyun Zhu, Tesa M. Severson, Alex Murison, Sarina Cameron, Wilbert Zwart, Theodorus van der Kwast, Trevor J. Pugh, Michael Fraser, Paul C. Boutros, Robert G. Bristow, Housheng Hansen He, Mathieu Lupien

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The Dockstore: enabling modular, community-focused sharing of Docker-based genomics tools and workflows [version 1; referees: 2 approved] by Brian D. O'Connor, Denis Yuen, Vincent Chung, Andrew G. Duncan, Xiang Kun Liu, Janice Patricia, Benedict Paten, Lincoln Stein, Vincent Ferretti

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Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes by Matthew A. Reyna, David Haan, Marta Paczkowska, Lieven P. C. Verbeke, Miguel Vazquez, Abdullah Kahraman, Sergio Pulido-Tamayo, Jonathan Barenboim, Lina Wadi, Priyanka Dhingra, Raunak Shrestha, Gad Getz, Michael S. Lawrence, Jakob Skou Pedersen, Mark A. Rubin, David A. Wheeler, Søren Brunak, Jose M. G. Izarzugaza, Ekta Khurana, Kathleen Marchal, Christian von Mering, S. Cenk Sahinalp, Alfonso Valencia, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, Joshua M. Stuart, Benjamin J. Raphael, PCAWG Consortium

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Author Correction: Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada by Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Marc R. Isabel, Richard de Borja, Philip C. Zuzarte, Calvin P. Sjaarda, Kevin R. Barker, Prameet M. Sheth, Larissa M. Matukas, Jonathan B. Gubbay, Allison J. McGeer, Samira Mubareka, Jared T. Simpson, Ramzi Fattouh

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Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response by Magdalena M. Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L. Couzens, Mohammad Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C. dela Seña, Tsukasa Sugo, Kozo Hayashi, David McLeod, Carlos Zepeda, Ahmed Aman, Maria Sánchez-Osuna, Eric Bonneil, Shinji Takagi, Rima Al-Awar, Mike Tyers, Stephane Richard, Masayuki Takizawa, Anne-Claude Gingras, Cheryl H. Arrowsmith, Masoud Vedadi, Peter J. Brown, Hiroshi Nara, Dalia Barsyte-Lovejoy

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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers by Joan Miguel Romero, Emma Titmuss, Yifan Wang, James Vafiadis, Alain Pacis, Gun Ho Jang, Amy Zhang, Bryn Golesworthy, Tatiana Lenko, Laura M. Williamson, Barbara Grünwald, Grainne M. O’Kane, Steven J. M. Jones, Marco. A. Marra, Julie M. Wilson, Steven Gallinger, Janessa Laskin, George Zogopoulos

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U2AF1S34/Q157 Variants Detected in cis Arise Sequentially in an MDS Patient With Serial Sequencing Spanning 18 Years by Christina K. Ferrone, Amy J. M. McNaughton, Felicia Vincelli, Philip Zuzarte, David Lee, Harriet E. Feilotter, Michael J. Rauh

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PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland by Purna A. Joshi, Paul D. Waterhouse, Katayoon Kasaian, Hui Fang, Olga Gulyaeva, Hei Sook Sul, Paul C. Boutros, Rama Khokha

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Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response by Magdalena M. Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L. Couzens, Mohammad Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C. dela Seña, Tsukasa Sugo, Kozo Hayashi, David McLeod, Carlos Zepeda, Ahmed Aman, Maria Sánchez-Osuna, Eric Bonneil, Shinji Takagi, Rima Al-Awar, Mike Tyers, Stephane Richard, Masayuki Takizawa, Anne-Claude Gingras, Cheryl H. Arrowsmith, Masoud Vedadi, Peter J. Brown, Hiroshi Nara, Dalia Barsyte-Lovejoy

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Human phospho‐signaling networks of SARS‐CoV‐2 infection are rewired by population genetic variants by Diogo Pellegrina, Alexander T Bahcheli, Michal Krassowski, Jüri Reimand

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Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes by Christian A. Lee, Diala Abd-Rabbo, Jüri Reimand

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Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada by Jennifer L. Guthrie, Sarah Teatero, Sandra Zittermann, Yao Chen, Ashleigh Sullivan, Heather Rilkoff, Esha Joshi, Karthikeyan Sivaraman, Richard de Borja, Yogi Sundaravadanam, Michael Laszloffy, Lawrence Heisler, Vanessa G. Allen, Jared T. Simpson, Nahuel Fittipaldi

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Immune responses of therapeutic lipid nanoparticles by Chen Weihsu Claire, May Jonathan P., Li Shyh-Dar

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Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns by Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid D. Morris, Lincoln D. Stein, PCAWG Consortium

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Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors by Aline C Planello, Junfeng Ji, Vivek Sharma, Rajat Singhania, Faridah Mbabaali, Fabian Müller, Javier A Alfaro, Christoph Bock, Daniel D De Carvalho, Nizar N Batada

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P081: Enhancing minimally invasive minimal residual disease detection of multiple myeloma using cell-free DNA whole-genome sequencing by Dor Abelman, Madhuran Thiagarajah, Felix Beaudry, Jenna Eagles, Stephanie Pederson, Jeffrey Bruce, Stephenie Prokopec, Danielle Croucher, Cecilia Bonolo De Campos, Arnavaz Danesh, Ellen Wei, Saumil Shah, Alli Murugesan, Anthony Reiman, Suzanne Trudel, Trevor Pugh

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Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates by Raghuveera Kumar Goel, Mona Meyer, Marta Paczkowska, Jüri Reimand, Frederick Vizeacoumar, Franco Vizeacoumar, TuKiet T. Lam, Kiven Erique Lukong

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Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma by Bryn Golesworthy, Bryn Golesworthy, Yifan Wang, Yifan Wang, Yifan Wang, Amanda Tanti, Amanda Tanti, Alain Pacis, Alain Pacis, Joan Miguel Romero, Joan Miguel Romero, Adeline Cuggia, Adeline Cuggia, Celine Domecq, Celine Domecq, Guillaume Bourdel, Guillaume Bourdel, Robert E. Denroche, Gun Ho Jang, Robert C. Grant, Ayelet Borgida, Barbara T. Grünwald, Anna Dodd, Julie M. Wilson, Guillaume Bourque, Guillaume Bourque, Grainne M. O’Kane, Grainne M. O’Kane, Sandra E. Fischer, Sandra E. Fischer, Chelsea Maedler Kron, Chelsea Maedler Kron, Pierre-Olivier Fiset, Pierre-Olivier Fiset, Atilla Omeroglu, Atilla Omeroglu, William D. Foulkes, William D. Foulkes, Steven Gallinger, Steven Gallinger, Steven Gallinger, Marie-Christine Guiot, Marie-Christine Guiot, Zu-Hua Gao, Zu-Hua Gao, George Zogopoulos, George Zogopoulos, George Zogopoulos

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Breast cancers are rare diseases—and must be treated as such by John M. S. Bartlett, Wendy Parelukar

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