Effectiveness of a nurse-delivered (FOCUS+) and a web-based (iFOCUS) psychoeducational intervention for people with advanced cancer and their family caregivers (DIAdIC): study prot... by Orphé Matthys, Aline De Vleminck, Sigrid Dierickx, Luc Deliens, Vincent Van Goethem, Lore Lapeire, Mogens Groenvold, Line Lund, Caroline Moeller Arnfeldt, Lisa Sengeloev, Helle Pappot, Anna Thit Johnsen, Suzanne Guerin, Philip J. Larkin, Catherine Jordan, Michael Connolly, Paul D’Alton, Massimo Costantini, Silvia Di Leo, Monica Guberti, Elena Turola, Agnes van der Heide, Erika Witkamp, Judith Rietjens, Maaike van der Wel, Kevin Brazil, Gillian Prue, Joanne Reid, David Scott, Katherine Bristowe, Richard Harding, Charles Normand, Peter May, Catherine Cronin, Laurel Northouse, Peter Hudson, Joachim Cohen

“…The interventions are based on the FOCUS intervention, developed in the USA, that addresses five core components: family involvement, optimistic outlook, coping effectiveness, uncertainty reduction, and symptom management. …”
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Water Resources Evaluation in Arid Areas Based on Agricultural Water Footprint—A Case Study on the Edge of the Taklimakan Desert by Lingyun Zhang, Yang Yu, Ireneusz Malik, Malgorzata Wistuba, Lingxiao Sun, Meiling Yang, Qian Wang, Ruide Yu

“…The agricultural water consumption was still within the range of local water resources that could be carried but only 6 years of sustainable water use, and the future development was not optimistic. With the ratio of produced WF to available water resources maintained at about 58%, the local available water resources should be above 43.21 × 10⁸ m³ to initially ensure the sustainable use of water resources. …”
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Correlation analysis between sleep quality and the mental health status of female sex workers during the COVID-19 pandemic in Hubei Province by Piyong Zhai, Hao Liu, Yutong Zhang, Tao Huang, Change Xiong, Yang Liu, Guiping Wang, Xin Chen, Jianhua Tan, Chengjun Jiao, Jianbo Zhan, Jing Cheng

“…NE/NA was a protective factor for sleep disorders (OR=0.042, P=0.05), with an AUC of 0.87.ConclusionFSWs should appropriately adjust their work form during the pandemic period, maintain a positive and optimistic attitude, establish long-term stable social relationships, and seek a greater sense of social support. …”
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Use of a smartphone app combined with gamification to increase the level of physical activity of adults and older adults: protocol of a sequential multiple assignment randomized tr... by Maria do Socorro Morais Pereira Simões, Bárbara de Barros Gonze, Neli Leite Proença, Vinicius Tonon Lauria, Vinícius Demarchi Silva Terra, Ricardo da Costa Padovani, Victor Zuniga Dourado

“…Following the SMART pilot, we will calculate the sample size for the trial based on the variation of the average number of steps/day, including an up to 40% loss to follow-up and a less optimistic nonresponse rate of 65%. Discussion To our knowledge, this will be the first trial with adaptive intervention to test the effectiveness of using a smartphone app to increase the level of physical activity of adults and older adults. …”
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Identification of N6-methylandenosine related lncRNA signatures for predicting the prognosis and therapy response in colorectal cancer patients by Zhiyong Li, Zhiyong Li, Zhiyong Li, Yang Liu, Huijie Yi, Huijie Yi, Ting Cai, Ting Cai, Yunwei Wei, Yunwei Wei

“…Thus, discerning sensitive prognostic biomarkers to give the optimistic treatment for CRC patients is extremely critical. …”
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Adaptation measures to global change in the Serpis River Basin (Spain): An evaluation considering agricultural benefits, environmental flows, and invasive fishes by Rafael Muñoz-Mas, Hector Macian-Sorribes, Francisco J. Oliva-Paterna, Lorenzo Sangelantoni, Daniele Peano, Manuel Pulido-Velazquez, Francisco Martínez-Capel

“…Although the maximum benefits will rarely be achieved, on average the modernisation expected in the RBMP would sustain agricultural incomes in the optimistic scenario (SSP1-2.6) and for the short term of the pessimistic scenario (SSP5-8.5), showing similar effects than the ongoing redistribution of agricultural plots. …”
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7295 elderly hospitalized patients with catheter-associated urinary tract infection: a case-control study by Li Shen, Ting Fu, Luguang Huang, Huiying Sun, Yu Wang, Lili Sun, Xiaoyun Lu, Jing Zhang, Zhaoxu Yang, Chunping Ni

“…Conclusion The situation of CAUTI in the elderly is not optimistic, it is easy to have a one-person multi-pathogen infection, and the proportion of fungi infection is not low. …”
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The knowledge and practice regarding disposal of waste insulin needles in patients with diabetes mellitus (糖尿病患者废弃胰岛素针头处理情况及相关因素分析) by LIU Huanhuan (刘欢欢), LIU Haiwei (刘海蔚), WU Yueli (吴月丽), ZENG Xiaocui (曾小翠), LIANG Changli (梁昌丽), LIANG Caiya (梁彩雅)

“…Conclusion The behaviors of disposing used insulin needles was not optimistic and medical staff should strengthen the education of disposing waste insulin needles, and promote the management of the disposal. …”
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Knowledge and attitude on prevention of COVID-19 among community health workers in Nepal-a cross-sectional study by Amul Shrestha, Tek Bahadur Thapa, Mahendra Giri, Sanjiv Kumar, Sakil Dhobi, Haikali Thapa, Pawan Prakash Dhami, Arun Shahi, Ajita Ghimire, Ela Singh Rathaur

“…Health care workers are knowledgeable about COVID-19 and are proactively practicing the preventive measures to minimize the spread of infection but some lack optimistic attitude. Hence, the constantly updated educational programs related to COVID-19 will surely contribute to improving the healthcare workers knowledge and attitude towards COVID-19.…”
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Uso de florestas secundárias por aves de sub-bosque em uma paisagem fragmentada na Amazônia central Use of secondary forests by understory birds in a fragmented landscape in centra... by João Vitor Campos e Silva, Beatriz Souza da Conceição, Marina Anciães

“…<br>Rates of deforestation in the Brazilian Amazon have increased since 1991 and forecasts are not optimistic about the slowing of this process. Some authors believe that the Amazon may be experiencing a massive process of species extinction. …”
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Serbia – an Oponent or an ally of Independent Macedonia (1991‑2013)? by Wojciech Szczepański

“…The submitted sketch is closed with an optimistic evaluation of the present conditions and perspectives of the relations between Serbia and Macedonia. …”
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Aspergillus flavus originated pure compound as a potential antibacterial by Saeed Ullah Khattak, Ghosia Lutfullah, Zafar Iqbal, Jamshaid Ahmad, Irshad Ur Rehman, Yanbin Shi, Saima Ikram

“…Abstract Problem Background Penicillin was the first and most famous fungal secondary metabolite used as broad spectrum antibiotic that revolutionarised pharmaceutical research and also saved millions of lives. The over optimistic belief in 1967 that sufficient antibiotics had been discovered to defeat infectious diseases was quickly crashed with the appearance of multidrug resistant (MDR) bacteria in 1990s. …”
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Climate change impacts the state of winter roads connecting indigenous communities: Case study of Sakha (Yakutia) Republic by Kyunney Kirillina, Nikita Tananaev, Antonina Savvinova, Vladimir Lobanov, Alla Fedorova, Aleksei Borisov

“…In the far future, 2071–2100, only under optimistic SSP 1–2.6 scenario the MMAT change is contained within +3.5 °C, and even in this case, April MMAT increases above −2°C at stations in southern Yakutia. …”
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Perceived Life Expectancy Among Dialysis Recipients: A Scoping Review by Hannah Beckwith, Amarpreet Thind, Edwina A. Brown

“…Limitations: There is a marked paucity of research in this area, with most studies conducted in North American cohorts. Conclusions: Optimistic patient prognostic expectations persist in dialysis recipients. …”
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The effect of an antibiotic stewardship program on tigecycline use in a Tertiary Care Hospital, an intervention study by Rima Moghnieh, Dania Abdallah, Lyn Awad, Marwa Jadayel, Nicholas Haddad, Hani Tamim, Aline Zaiter, Diana-Caroline Awwad, Loubna Sinno, Salam El-Hassan, Rawad Lakkis, Rabab Khalil, Tamima Jisr

“…Conclusion The drug-oriented ASP intervention targeting tigecycline prescriptions improved its use and patient outcomes, where it helped curb the over-optimistic use of this drug in off-label indications where it is not a suitable treatment option.…”
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Construct a classification decision tree model to select the optimal equation for estimating glomerular filtration rate and estimate it more accurately by Zhenliang Fan, Qiaorui Yang, Zhuohan Xu, Ke Sun, Mengfan Yang, Riping Yin, Dongxue Zhao, Junfen Fan, Hongzhen Ma, Yiwei Shen, Hong Xia

“…However, the accuracy of the equations for estimating GFR is not optimistic. To estimate GFR more precisely, we constructed a classification decision tree model to select the most befitting GFR estimation equation for CKD patients. …”
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The assessment and appraisal of regenerative medicines and cell therapy products: an exploration of methods for review, economic evaluation and appraisal by Robert Hettle, Mark Corbett, Sebastian Hinde, Robert Hodgson, Julie Jones-Diette, Nerys Woolacott, Stephen Palmer

“…The relative treatment effects generated from single-arm trials are likely to be optimistic unless it is certain that the historical data have accurately estimated the efficacy of the control agent. …”
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Comparison of Machine Learning and Land Use Regression for fine scale spatiotemporal estimation of ambient air pollution: Modeling ozone concentrations across the contiguous United... by Xiang Ren, Zhongyuan Mi, Panos G. Georgopoulos

“…Six target-oriented validation strategies were used to prevent overfitting and avoid over-optimistic model evaluation results. In order to take full advantage of the power of different algorithms, we introduced tuning sample weights in spatiotemporal modeling to ensure predictive accuracy of peak concentrations, that is crucial for exposure assessments. …”
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Abordando la crisis de los Recursos Humanos para la Salud: ¿Hasta dónde hemos llegado? ¿Qué podemos esperar lograr al 2015? Addressing the Human Resources for Health crisis in coun... by Manuel M. Dayrit, Carmen Dolea, Norbert Dreesch

“…While the authors wish to remain optimistic about the striving towards this target, their optimism must be matched by an adequate level of investment in countries on HRH development. …”
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Modeling of the factors influencing the dairy market in Ukraine by Nataliia Kosar, Nataliia Kuzo, Jacek Binda, Nataliya Hayvanovych, Nataliya Pytulyak

“…By using the developed models, the authors calculated the expected volume of milk consumption per capita under increasing prices of milk and reducing number of cattle and the optimistic scenarios of agriculture development under martial law. …”
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