Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis by Taha Azad, Reza Rezaei, Abera Surendran, Ragunath Singaravelu, Stephen Boulton, Jaahnavi Dave, John C. Bell, Carolina S. Ilkow

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Vanadyl sulfate-enhanced oncolytic virus immunotherapy mediates the antitumor immune response by upregulating the secretion of pro-inflammatory cytokines and chemokines by Nouf Alluqmani, Nouf Alluqmani, Nouf Alluqmani, Anna Jirovec, Anna Jirovec, Zaid Taha, Zaid Taha, Oliver Varette, Andrew Chen, Daniel Serrano, Glib Maznyi, Sarwat Khan, Nicole E. Forbes, Rozanne Arulanandam, Rebecca C. Auer, Rebecca C. Auer, Jean-Simon Diallo, Jean-Simon Diallo

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Transcriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture Scheme by Richard L. Carpenedo, Sarah Y. Kwon, R. Matthew Tanner, Julien Yockell-Lelièvre, Chandarong Choey, Carole Doré, Mirabelle Ho, Duncan J. Stewart, Theodore J. Perkins, William L. Stanford

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Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference by Donald Bastin, Amelia S. Aitken, Adrian Pelin, Larissa A. Pikor, Mathieu J. F. Crupi, Michael S. Huh, Marie-Claude Bourgeois-Daigneault, John C. Bell, Carolina S. Ilkow

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Parkin coregulates glutathione metabolism in adult mammalian brain by Daniel N. El Kodsi, Jacqueline M. Tokarew, Rajib Sengupta, Nathalie A. Lengacher, Ajanta Chatterji, Angela P. Nguyen, Heather Boston, Qiubo Jiang, Carina Palmberg, Chantal Pileggi, Chet E. Holterman, Bojan Shutinoski, Juan Li, Travis K. Fehr, Matthew J. LaVoie, Rajiv R. Ratan, Gary S. Shaw, Masashi Takanashi, Nobutaka Hattori, Christopher R. Kennedy, Mary-Ellen Harper, Arne Holmgren, Julianna J. Tomlinson, Michael G. Schlossmacher

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Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors by Li Zhang, Zhaohong Qin, Konrad M. Ricke, Shelly A. Cruz, Alexandre F. R. Stewart, Hsiao-Huei Chen

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Effect and outcome of equity, diversity and inclusion programs in healthcare institutions: a systematic review protocol by Marco Solmi, Manish M Sood, Kathryn Lee, Ayub Akbari, Gregory L Hundemer, Amos Buh, Rachel Kang, Rohan Kiska, Stephen G Fung, Mekaylah Scott, Maria Salman, Benjamin Milone, Gamal Wafy, Sarah Syed, Shan Dhaliwal, Maya Gibb, Pierre A Brown

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Oncolytic vesicular stomatitis virus expressing interferon-σ has enhanced therapeutic activity by Marie-Claude Bourgeois-Daigneault, Dominic Guy Roy, Theresa Falls, Kwame Twumasi-Boateng, Lauren Elizabeth St-Germain, Monique Marguerie, Vanessa Garcia, Mohammed Selman, Victoria Ann Jennings, Jessica Pettigrew, Sally Amos, Jean-Simon Diallo, Brad Nelson, John Cameron Bell

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A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion by Taha Azad, Reza Rezaei, Ragunath Singaravelu, Taylor R. Jamieson, Mathieu J. F. Crupi, Abera Surendran, Joanna Poutou, Parisa Taklifi, Juthaporn Cowan, Donald William Cameron, Carolina S. Ilkow

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Poly(I:C) enhances mesenchymal stem cell control of myeloid cells from COVID-19 patients by Luciana Souza-Moreira, Yuan Tan, Yan Wang, Jia-Pey Wang, Mahmoud Salkhordeh, Jennifer Virgo, Maria Florian, Aidan B.P. Murray, Irene Watpool, Lauralyn McIntyre, Shane English, Duncan J. Stewart, Shirley H.J. Mei

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Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial by Manoj M Lalu, Katrina J Sullivan, Shirley HJ Mei, David Moher, Alexander Straus, Dean A Fergusson, Duncan J Stewart, Mazen Jazi, Malcolm MacLeod, Brent Winston, John Marshall, Brian Hutton, Keith R Walley, Lauralyn McIntyre, on behalf of the Canadian Critical Care Translational Biology Group

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Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus by Zaid Taha, Zaid Taha, Mathieu J.F. Crupi, Mathieu J.F. Crupi, Nouf Alluqmani, Nouf Alluqmani, Faiha Fareez, Kristy Ng, Judy Sobh, Emily Lee, Andrew Chen, Max Thomson, Marcus M. Spinelli, Carolina S. Ilkow, Carolina S. Ilkow, John C. Bell, John C. Bell, Rozanne Arulanandam, Jean-Simon Diallo, Jean-Simon Diallo

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Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer Therapy by Adrian Pelin, Johann Foloppe, Julia Petryk, Ragunath Singaravelu, Marian Hussein, Florian Gossart, Victoria A. Jennings, Lawton J. Stubbert, Madison Foster, Christopher Storbeck, Antonio Postigo, Elena Scut, Brian Laight, Michael Way, Philippe Erbs, Fabrice Le Boeuf, John C. Bell

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Hematologists’ barriers and enablers to screening and recruiting patients to a chimeric antigen receptor (CAR) T cell therapy trial: a theory-informed interview study by Gisell Castillo, Manoj Lalu, Sarah Asad, Madison Foster, Natasha Kekre, Dean Fergusson, Terry Hawrysh, Harold Atkins, Kednapa Thavorn, Joshua Montroy, Stuart Schwartz, Robert Holt, Raewyn Broady, Justin Presseau, on behalf of the GO CART team

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FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models by Kristianne J. C. Galpin, Galaxia M. Rodriguez, Vincent Maranda, David P. Cook, Elizabeth Macdonald, Humaira Murshed, Shan Zhao, Curtis W. McCloskey, Andrzej Chruscinski, Gary A. Levy, Michele Ardolino, Barbara C. Vanderhyden

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Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation by Alessandra Pasut, Natasha C. Chang, Uxia Gurriaran Rodriguez, Sharlene Faulkes, Hang Yin, Melanie Lacaria, Hong Ming, Michael A. Rudnicki

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BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy by Salar Farokhi Boroujeni, Galaxia Rodriguez, Kristianne Galpin, Edward Yakubovich, Humaira Murshed, Dalia Ibrahim, Sara Asif, Barbara C. Vanderhyden

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GLI3 regulates muscle stem cell entry into GAlert and self-renewal by Caroline E. Brun, Marie-Claude Sincennes, Alexander Y. T. Lin, Derek Hall, William Jarassier, Peter Feige, Fabien Le Grand, Michael A. Rudnicki

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MLL1 is required for PAX7 expression and satellite cell self-renewal in mice by Gregory C. Addicks, Caroline E. Brun, Marie-Claude Sincennes, John Saber, Christopher J. Porter, A. Francis Stewart, Patricia Ernst, Michael A. Rudnicki

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Diagnostic Accuracy of MRS in the Preoperative Identification of Isocitrate Dehydrogenase Mutation in Patients with Gliomas by Fahad Alkherayf, Thanh Nguyen, Gerd Melkus, Ryan Gotfrit, Carlos H. Torres, Nader Zakhari, Santanu Chakraborty, Gerard Jansen, Mattew D. McInnes, Rafael Ochoa-Sanchez, Rebecca E. Thornhill, Ian Cameron

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