Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells by Satish Ranjan, Alexander Goihl, Shrey Kohli, Ihsan Gadi, Mandy Pierau, Khurrum Shahzad, Dheerendra Gupta, Fabian Bock, Hongjie Wang, Haroon Shaikh, Thilo Kähne, Dirk Reinhold, Ute Bank, Ana C. Zenclussen, Jana Niemz, Tina M. Schnöder, Monika Brunner-Weinzierl, Thomas Fischer, Thomas Kalinski, Burkhart Schraven, Thomas Luft, Jochen Huehn, Michael Naumann, Florian H. Heidel, Berend Isermann

Get full text

Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function by Denise Wolleschak, Thomas S. Mack, Florian Perner, Stephanie Frey, Tina M. Schnöder, Marie-Christine Wagner, Christine Höding, Marina C. Pils, Andreas Parkner, Stefanie Kliche, Burkhart Schraven, Katrin Hebel, Monika Brunner-Weinzierl, Satish Ranjan, Berend Isermann, Daniel B. Lipka, Thomas Fischer, Florian H. Heidel

Get full text

HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience by Syed Ahsan Raza, Anne Albrecht, Gürsel Çalışkan, Bettina Müller, Yunus Emre Demiray, Susann Ludewig, Susanne Meis, Nicolai Faber, Roland Hartig, Burkhart Schraven, Volkmar Lessmann, Herbert Schwegler, Oliver Stork

Get full text

SDF1α-induced chemotaxis of JAK2-V617F-positive cells is dependent on Bruton tyrosine kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA by Subbaiah Chary Nimmagadda, Stephanie Frey, Peter Müller, Denise Wolleschak, Sönke Weinert, Ulrich Keller, Bärbel Edelmann, Thomas Fischer

Get full text

c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice by Ute Bank, Katrin Deiser, Carlos Plaza-Sirvent, Lisa Osbelt, Amelie Witte, Laura Knop, Rebecca Labrenz, Robert Jänsch, Felix Richter, Aindrila Biswas, Ana C. Zenclussen, Eric Vivier, Chiara Romagnani, Anja A. Kühl, Ildiko R. Dunay, Till Strowig, Ingo Schmitz, Thomas Schüler

Get full text

Beneficial Effects of Low Frequency Vibration on Human Chondrocytes in Vitro by Ronald Lützenberg, Markus Wehland, Kendrick Solano, Mohamed Z. Nassef, Christoph Buken, Daniela Melnik, Johann Bauer, Sascha Kopp, Marcus Krüger, Stefan Riwaldt, Ruth Hemmersbach, Herbert Schulz, Manfred Infanger, Daniela Grimm

Get full text

AMYGDALAR REGULATION OF MEMORY ENGRAMS IN THE HIPPOCAMPUS by Sara Enrile Lacalle, Ahsan Raza, Oliver Stork, Gürsel Caliskan

Get full text

Thalamic theta phase alignment predicts human memory formation and anterior thalamic cross-frequency coupling by Catherine M Sweeney-Reed, Tino Zaehle, Jürgen Voges, Friedhelm C Schmitt, Lars Buentjen, Klaus Kopitzki, Hermann Hinrichs, Hans-Jochen Heinze, Michael D Rugg, Robert T Knight, Alan Richardson-Klavehn

Get full text

Coding variants of the interleukin-11 receptor with reduced protein maturation show protease-dependent trans-signaling and transduce normal STAT3 signaling by Birte Kespohl, Roland Hartig, Yvonne Garbers, Juliane Lokau, Christoph Garbers

Get full text

Genetic Knock-out of TNFR1 and TNFR2 in a JAK2-V617F Polycythemia Vera Mouse Model by Peter Müller, Conny K. Baldauf, Tobias R. Haage, Emmanouil Charakopoulos, Martin Böttcher, Vikas Bhuria, Dimitrios Mougiakakos, Burkhart Schraven, Thomas Fischer

Get full text

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc by Anna Krone, Yan Fu, Simon Schreiber, Johanna Kotrba, Loisa Borde, Aileen Nötzold, Christoph Thurm, Jonas Negele, Tobias Franz, Sabine Stegemann-Koniszewski, Jens Schreiber, Christoph Garbers, Aniruddh Shukla, Robert Geffers, Burkhart Schraven, Dirk Reinhold, Anne Dudeck, Annegret Reinhold, Andreas J. Müller, Sascha Kahlfuss

Get full text

Expression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo by Caroline Ebert, Florian Perner, Denise Wolleschak, Tina M. Schnöder, Thomas Fischer, Florian H. Heidel

Get full text

Pleiotropic effects of antibiotics on T cell metabolism and T cell-mediated immunity by Tobias Franz, Jonas Negele, Philipp Bruno, Martin Böttcher, Martin Böttcher, Marisa Mitchell-Flack, Lea Reemts, Anna Krone, Dimitrios Mougiakakos, Dimitrios Mougiakakos, Andreas J. Müller, Andreas J. Müller, Andreas E. Zautner, Andreas E. Zautner, Sascha Kahlfuss, Sascha Kahlfuss, Sascha Kahlfuss, Sascha Kahlfuss

Get full text

Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults by Aditya Arra, Maximilian Pech, Hang Fu, Holger Lingel, Franziska Braun, Christian Beyer, Myra Spiliopoulou, Barbara M. Bröker, Karen Lampe, Christoph Arens, Katrin Vogel, Mandy Pierau, Monika C. Brunner-Weinzierl

Get full text

Evaluation of endourological tools to improve the diagnosis and therapy of ureteral tumors – from model development to clinical application by Wagner D., Porsch M., Detert M., Bartel F., Siedentopf S., Schindele D., Wendler JJ., Lux A., Schmidt B., Schostak M., Liehr UB.

Get full text

The opposing forces of shear flow and sphingosine-1-phosphate control marginal zone B cell shuttling by Kerry Tedford, Michael Steiner, Stanislav Koshutin, Karin Richter, Laura Tech, Yannik Eggers, Inga Jansing, Kerstin Schilling, Anja Erika Hauser, Mark Korthals, Klaus-Dieter Fischer

Get full text

Clinical, neuropsychological, and pre-stimulus dorsomedial thalamic nucleus electrophysiological data in deep brain stimulation patients by Catherine M. Sweeney-Reed, Tino Zaehle, Jürgen Voges, Friedhelm C. Schmitt, Lars Buentjen, Klaus Kopitzki, Alan Richardson-Klavehn, Hermann Hinrichs, Hans-Jochen Heinze, Robert T. Knight, Michael D. Rugg

Get full text

Can transcranial alternating current stimulation (tACS) reduce fatigability-related oscillatory brain activity changes? by Stefanie Linnhoff, Aiden Haghikia, Tino Zaehle

Get full text

Ventrointermediate thalamic stimulation improves motor learning in humans by Angela Voegtle, Laila Terzic, Amr Farahat, Nanna Hartong, Imke Galazky, Hermann Hinrichs, Slawomir J. Nasuto, Adriano de Oliveira Andrade, Robert T. Knight, Richard B. Ivry, Jürgen Voges, Matthias Deliano, Lars Buentjen, Catherine M. Sweeney-Reed

Get full text

Integrated biophysical matching of bacterial nanocellulose coronary artery bypass grafts towards bioinspired artery typical functions by Jörn Hülsmann, Theresa Fraune, Baratha Dodawatta, Fabian Reuter, Martin Beutner, Viktoria Beck, Matthias Hackert-Oschätzchen, Claus Dieter Ohl, Katja Bettenbrock, Gabor Janiga, Jens Wippermann, Max Wacker

Get full text