Natural killer cell-mediated immunopathology in recurrent pregnancy losses by Thanh Luu, Lujain AlSubki, Katherine Wolf, Amy Thees, Umida Ganieva, Svetlana Dambaeva, Kenneth Beaman, Joanne Kwak-Kim

“…During the ovarian cycle and pregnancy, peripheral NK (pNK) and uterine NK (uNK) cells dynamically change their proportions and cytotoxicities to prepare and accommodate invading trophoblast and maintain pregnancy. …”
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mAb14, a Monoclonal Antibody against Cell Surface PCNA: A Potential Tool for Sezary Syndrome Diagnosis and Targeted Immunotherapy by Jamal Knaneh, Emmilia Hodak, Shlomit Fedida-Metula, Avishay Edri, Rachel Eren, Yael Yoffe, Iris Amitay-Laish, Hadas Prag Naveh, Ido Lubin, Angel Porgador, Lilach Moyal

“…In the co-culture of peripheral blood NK (pNK) cells with CTCL lines, mAb14 increased the secretion of IFN-γ, indicating the reactivation of pNK activity. …”
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Constructing of <i>Bacillus subtilis</i>-Based Lux-Biosensors with the Use of Stress-Inducible Promoters by Andrew G. Kessenikh, Uliana S. Novoyatlova, Sergey V. Bazhenov, Eugeniya A. Stepanova, Svetlana A. Khrulnova, Eugeny Yu. Gnuchikh, Vera Yu. Kotova, Anna A. Kudryavtseva, Maxim V. Bermeshev, Ilya V. Manukhov

“…Here, we present a new lux-biosensor based on <i>Bacillus subtilis</i> for detecting of DNA-tropic and oxidative stress-causing agents. Hybrid plasmids pNK-DinC, pNK-AlkA, and pNK-MrgA have been constructed, in which the <i>Photorhabdus luminescens</i> reporter genes <i>luxABCDE</i> are transcribed from the stress-inducible promoters of <i>B. subtilis</i>: the SOS promoter P<i>dinC</i>, the methylation-specific response promoter P<i>alkA</i>, and the oxidative stress promoter P<i>mrgA</i>. …”
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Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway. by Jintang Sun, Meixiang Yang, Yanli Ban, Wenjuan Gao, Bingfeng Song, Yang Wang, Yun Zhang, Qianqian Shao, Beihua Kong, Xun Qu

“…In addition, clinical data showed that abnormal Tim-3 level on pNK might be associated with recurrent spontaneous abortion (RSA). …”
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Interview: Sophie Muller by Sophie Muller

“…Muller’s extensive body of work includes music videos for Rihanna, Radiohead, Gwen Stefani, Beyoncé, Bjork, Coldplay, Bebe Rexha, P!nk, The Cure, Kings of Leon, Nelly Furtado, Maroon 5, Alicia Keys, The Killers, Morrisey, Blur and Beck. …”
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Genotoxic Effect of Dicyclopropanated 5-Vinyl-2-Norbornene by Uliana S. Novoyatlova, Andrei G. Kessenikh, Olga V. Kononchuk, Sergey V. Bazhenov, Alexander A. Fomkin, Anna A. Kudryavtseva, Sergey V. Shorunov, Maxim V. Bermeshev, Ilya V. Manukhov

“…The highest toxic effect of dcpVNB is detected by the following <i>lux</i>-biosensors: <i>E. coli</i> pColD-lux, <i>E. coli</i> pDps, <i>B. subtilis</i> pNK-DinC, and <i>B. subtilis</i> pNK-MrgA, in which the genes of bacterial luciferases are transcriptionally fused to the corresponding promoters: P<i>_cda</i>, P<i>_dps</i>, P<i>_dinC</i>, and P<i>_mrgA</i>. …”
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Diagnostic significance of assessing peripheral natural killer cells in women with recurrent pregnancy loss by K. E. Gotsiridze, N. P. Kintraya

“…Aim: to assess peripheral blood NK cell (pNK) counts in women with recurrent pregnancy loss.Materials and Methods. …”
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Immune factors associated with the pathological and therapeutic effects of preoperative chemotherapy in patients with breast cancer by Ryungsa Kim, Ami Kawai, Megumi Wakisaka, Sayaka Sawada, Mika Shimoyama, Naomi Yasuda, Masayuki Hidaka, Yukitaka Morita, Shoichiro Ohtani, Mitsuya Ito, Kensuke Kawasaki, Takanori Kin, Koji Arihiro

“…Peripheral natural killer (pNK) cell activity and the neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, and platelet-lymphocyte ratio (PLR) were assessed before and after chemotherapy. …”
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Digital Signature Scheme Based on a New Hard Problem by Nikolay A. Moldovyan

“…This paper introduces a new hard computational problem that consists in finding the k th roots modulo large prime p=Nk2+1 where N is an even number and k is a prime with the length |k|≥160. …”
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Unique metabolism and protein expression signature in human decidual NK cells by Ping Wang, Ping Wang, Tingting Liang, Tingting Liang, Heqin Zhan, Mingming Zhu, Mingming Zhu, Mingming Wu, Mingming Wu, Lili Qian, Ying Zhou, Fang Ni, Fang Ni

“…Notably, compared to peripheral blood NK (pNK) cells, 29 metabolites involved in glycerophospholipid and glutathione metabolism were significantly decreased in dNK cells. …”
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Limited response of NK92 cells to <it>Plasmodium falciparum</it>-infected erythrocytes by Kremsner Peter G, Hoang Van, Böttger Evelyn, de Carvalho Elisandra, Kun Jürgen FJ

“…In this study, the suitability of NK92 cells as models for the NK mechanisms involved in the immune response against malaria was investigated.</p> <p>Methods</p> <p>NK92 cells were assessed for several signs of activation and cytotoxicity due to contact to parasites and were as well examined by oligonucleotide microarrays for an insight on the impact <it>P. falciparum</it>-infected erythrocytes have on their transcriptome. …”
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Yerli Üretilen Fitaz Enziminin Yumurta Tavuklarının Performans ve Yumurta Kalite Özellikleri Üzerine Etkileri by Engin Yeni̇ce, Deniz Karasu, Serdar Kamanlı

“…Deneme grupları; kontrol (% 0.35 yararlanılabilir P) (PK), negatif kontrol (% 0.25 yararlanılabilir P) (NK), NK+600 FTU/kg yem deneysel fitaz (DF) ve NK+600 FTU/kg yem ticari fitaz (TF) şeklinde oluşturulmuştur. …”
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Tissue detection of natural killer cells in colorectal adenocarcinoma by Patsouris Efstratios S, Mavrogiannis Christos, Papas Maria G, Kavantzas Nikos, Apostolopoulos Periklis, Lazaris Andreas Ch, Papanikolaou Ioannis S, Archimandritis Athanasios

“…The cases were characterized according to: patient gender and age, tumor location, size, grade, bowel wall invasion, lymph node metastases and Dukes' stage.</p> <p>Results</p> <p>NK cells were detected in 79/82 cases at the primary tumor site, 27/33 metastatic lymph nodes and 3/4 hepatic metastases; they were detected in levels similar to those reported in the literature, but their presence was not correlated to the clinical or pathological characteristics of the series, except for a negative association with the patients' age (p = 0.031).…”
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NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury by Frances Corrigan, Ibolja Cernak, Kelly McAteer, Sarah C. Hellewell, Jeffrey V. Rosenfeld, Renée J. Turner, Robert Vink

“…Post-injury administration of a substance P, NK1 receptor antagonist attenuated the injury-induced phosphorylation of tau by modulating the activity of several key kinases including Akt, ERK1/2 and JNK, and was associated with improvement in neurological outcome. …”
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Xenoantigen, an αGal epitope-expression construct driven by the hTERT-promoter, specifically kills human pancreatic cancer cell line by Fuchinoue Shohei, Hatori Keiko, Yoshimura Naoko, Yamada Osamu, Sawada Tokihiko, Teraoka Satoshi

“…To induce cancer cell specific transcription of the αGal epitope, an expression vector which synthesizes the αGal epitope under the control of a promoter region of the human telomerase reverse transcriptase (hTERT), NK7, was constructed.</p> <p>Methods</p> <p>NK7 was transfected into a human pancreatic carcinoma cell line, MIA cells, and telomerase-negative SUSM-1 cells served controls. …”
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Natural Killer Cells: An Insight into its Role in Pregnancy by Shailaza Shrestha, Preeti Sharma, Pradeep Kumar, SP Saxena, Rachna Sharma

“…In contrast to peripheral NK (pNK) cells, uterine NK (uNK) cells are not the killer cells, rather they provide a suitable microenvironment in the pregnant uterus making it compatible to the growing foetus and promoting normal placentation, vascular remodeling and trophoblast infiltration, all of which are essential for healthy pregnancy. …”
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Ecological stoichiometry and environmental influencing factors of soil nutrients in the karst rocky desertification ecosystem, southwest China by Linjiao Wang, Pan Wang, Maoyin Sheng, Jing Tian

“…The average values of C:N, C:P, C:K, N:P, N:K and P:K were 19.56, 65.07, 23.65, 3.45, 1.32 and 0.39, respectively. …”
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Effects of Substance P and Neurokinin A on the Contractile Activity of Inflamed Porcine Uterus by Marta Brzozowska, Marta Romaniewicz, Jarosław Całka, Barbara Jana

“…Here, we determined the effect of <i>Escherichia coli</i> (<i>E. coli)</i>-induced inflammation on expression of protein receptor subtypes for substance P (NK1R) and neurokinin A (NK2R) in the pig myometrium as well as their role in contractility of inflamed uterus. …”
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Simplified All-In-One CRISPR-Cas9 Construction for Efficient Genome Editing in <i>Cryptococcus</i> Species by Ping Zhang, Yu Wang, Chenxi Li, Xiaoyu Ma, Lan Ma, Xudong Zhu

“…Here, we report the optimized and simplified construction method for all-in-one CRISPR-Cas9 vectors that can be used in <i>C. neoformans</i> and <i>C. deneoformans</i> strains respectively, named pNK003 (Genbank: MW938321) and pRH003 (Genbank: KX977486). …”
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Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines by MacLeod Roderick AF, Scherr Michaela, Kaufmann Maren, Meyer Corinna, Marquez Victor E, Venturini Letizia, Nagel Stefan, Drexler Hans G

“…<p>Abstract</p> <p>Background</p> <p>NK- and T-cells are closely related lymphocytes, originating from the same early progenitor cells during hematopoiesis. …”
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