Liposome Formulations for the Strategic Delivery of PARP1 Inhibitors: Development and Optimization by Carlota J. F. Conceição, Elin Moe, Paulo A. Ribeiro, Maria Raposo

Subjects: “…PARP1 inhibitors…”
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Neuroprotective Effects of PARP Inhibitors in <i>Drosophila</i> Models of Alzheimer’s Disease by Anna Maggiore, Assunta Maria Casale, Walter Toscanelli, Ugo Cappucci, Dante Rotili, Maddalena Grieco, Jean-Philippe Gagné, Guy G. Poirier, Maria d’Erme, Lucia Piacentini

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Structurally unique PARP‐1 inhibitors for the treatment of prostate cancer by Ali Divan, Mukund P. Sibi, Alexei Tulin

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Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer’s Disease by Felipe Salech, Felipe Salech, Felipe Salech, Daniela P. Ponce, Andrea C. Paula-Lima, Andrea C. Paula-Lima, Andrea C. Paula-Lima, Carol D. SanMartin, Carol D. SanMartin, María I. Behrens, María I. Behrens, María I. Behrens, María I. Behrens

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Unsymmetric Cisplatin-Based Pt(IV) Conjugates Containing a PARP-1 Inhibitor Pharmacophore Tested on Malignant Pleural Mesothelioma Cell Lines by Elisabetta Gabano, Giulia Pinton, Cecilia Balzano, Sara Boumya, Domenico Osella, Laura Moro, Mauro Ravera

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Poly (ADP-Ribose) polymerase 1 and parthanatos in neurological diseases: From pathogenesis to therapeutic opportunities by Xiaoxue Xu, Bowen Sun, Chuansheng Zhao

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Interactions of PARP1 Inhibitors with PARP1-Nucleosome Complexes by Natalya Maluchenko, Darya Koshkina, Anna Korovina, Vasily Studitsky, Alexey Feofanov

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Hsa-miR-155-5p Up-Regulation in Breast Cancer and Its Relevance for Treatment With Poly[ADP-Ribose] Polymerase 1 (PARP-1) Inhibitors by Barbara Pasculli, Raffaela Barbano, Andrea Fontana, Tommaso Biagini, Maria Pia Di Viesti, Michelina Rendina, Vanna Maria Valori, Maria Morritti, Sara Bravaccini, Sara Ravaioli, Evaristo Maiello, Paolo Graziano, Roberto Murgo, Massimiliano Copetti, Tommaso Mazza, Vito Michele Fazio, Manel Esteller, Manel Esteller, Manel Esteller, Manel Esteller, Paola Parrella

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PARP‐1 Inhibition Increases Oxidative Stress in Ets‐1‐Expressing MDA‐MB‐231 Breast Cancer Cells by Magalie Hervieu, Arnaud J. Legrand, Emilie Floquet, Thierry Idziorek, Corentin Spriet, Didier Monté, Vincent Villeret, Marc Aumercier, Souhaila Choul‐li

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PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models by Ymera Pignochino, Federica Capozzi, Lorenzo D’Ambrosio, Carmine Dell’Aglio, Marco Basiricò, Marta Canta, Annalisa Lorenzato, Francesca Vignolo Lutati, Sandra Aliberti, Erica Palesandro, Paola Boccone, Danilo Galizia, Sara Miano, Giulia Chiabotto, Lucia Napione, Loretta Gammaitoni, Dario Sangiolo, Maria Serena Benassi, Barbara Pasini, Giovanna Chiorino, Massimo Aglietta, Giovanni Grignani

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MAPK4 deletion enhances radiation effects and triggers synergistic lethality with simultaneous PARP1 inhibition in cervical cancer by Shuzhen Tian, Lili Lou, Mengyuan Tian, Guangping Lu, Jianghua Tian, Xi Chen

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Comprehensive machine learning boosts structure-based virtual screening for PARP1 inhibitors by Klaudia Caba, Viet-Khoa Tran-Nguyen, Taufiq Rahman, Pedro J. Ballester

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Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors by Jiang Yu, Wenfeng Gou, Haihua Shang, Yating Cui, Xiao Sun, Lingling Luo, Wenbin Hou, Tiemin Sun, Yiliang Li

Subjects: “…PARP-1 inhibitor…”
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Discovery of novel 2,3,4,5-tetrahydrospiro[benzo[c]azepine-1,1’-cyclohexan]-5-ol derivatives as PARP-1 inhibitors by Ling Yu, Jian-hui Li, Ju Zhu, You-de Wang, Zhi-wei Yan, Li-ying Zhang, Shuai Li

Subjects: “…PARP-1 inhibitor…”
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First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of a Neuroprotective Poly (ADP‐ribose) Polymerase‐1 Inhibitor, JPI-289, in Healthy Volunteers by Han S, Kim YH, Choi HY, Soh DJ, Kim J, Nam J, Kim JW, Bae KS, Lim HS

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Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors by Cheng-Zhi Gao, Wei Dong, Zhi-Wen Cui, Qiong Yuan, Xia-Min Hu, Qing-Ming Wu, Xianlin Han, Yao Xu, Zhen-Li Min

Subjects: “…parp-1 inhibitor…”
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Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening by Danfeng Shi, Qianqian Pang, Qianyu Qin, Xinsheng Yao, Xiaojun Yao, Yang Yu

Subjects: “…PARP-1 inhibitor…”
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Transcriptional regulation mechanism of PARP1 and its application in disease treatment by Yu Lu, Wenliang Fu, Weiwei Xing, Haowei Wu, Chao Zhang, Donggang Xu

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ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1 by Li-Li Yang, Meng Li, Wei Huang, Peng-Tao Ren, Qing-Hui Yan, Ying-Hao Hao

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Pyrido[2′,1′:2,3]imidazo[4,5-<i>c</i>]isoquinolin-5-amines as Potential Cytotoxic Agents against Human Neuroblastoma by Zahira Tber, Mohammed Loubidi, Jabrane Jouha, Ismail Hdoufane, Mümin Alper Erdogan, Luciano Saso, Güliz Armagan, Sabine Berteina-Raboin

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