Revisiting PI3-kinase signalling in angiogenesis by Piotr Kobialka, Mariona Graupera

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REGULATION OF GLYCOLYSIS ON HIPPOCAMPAL SLICES BY PI3 KINASES by Eneko Merino-Casamayor, Silvia Gutiérrez-Eisman, Alba Fernández-Rodrigo, Jose Esteban

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Polarization of migrating monocytic cells is independent of PI 3-kinase activity. by Silvia Volpe, Sylvia Thelen, Thomas Pertel, Martin J Lohse, Marcus Thelen

“…The process appears to be independent of PI 3-kinase activity.…”
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Activated PI3 Kinase Delta Syndrome: From Genetics to Therapy by David Michalovich, Sergey Nejentsev

Subjects: “…activated PI3 kinase delta syndrome…”
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An updated review on activated PI3 kinase delta syndrome (APDS) by Ankita Singh, Vibhu Joshi, Ankur Kumar Jindal, Babu Mathew, Amit Rawat

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Modifying radiosensitivity in tumors: Targeting the Ras-PI-3 kinase pathway. by Muschel, R, Gupta, A, Bernhard, E, McKenna, G

A PI3-kinase-mediated negative feedback regulates neuronal excitability. by Eric Howlett, Curtis Chun-Jen Lin, William Lavery, Michael Stern

“…We show that DmGluRA mutations increase neuronal excitability by preventing PI3 kinase (PI3K) activation and consequently hyperactivating the transcription factor Foxo. …”
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p110d PI3 kinase pathway: emerging roles in cancer by Niki eTzenaki, Evangelia A Papakonstanti

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Synthesis and PI3 Kinase Inhibition Activity of a Wortmannin-Leucine Derivative by William Cantrell, Yue Huang, Antonio A. Menchaca, George Kulik, Mark E. Welker

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PI3-Kinase δγ Catalytic Isoforms Regulate the Th-17 Response in Tuberculosis by Gina R. Leisching

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Drosophila Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling. by Einat Cinnamon, Rami Makki, Annick Sawala, Leah P Wickenberg, Gary J Blomquist, Claus Tittiger, Ze'ev Paroush, Alex P Gould

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The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase. by Fabiana H M Melo, Diego Butera, Mara de Souza Junqueira, Daniel K Hsu, Ana Maria Moura da Silva, Fu-Tong Liu, Marinilice F Santos, Roger Chammas

“…The promigratory activity of extracellular galectin-3 was inhibitable by wortmannin, implicating the activation of a PI-3 kinase dependent pathway in the galectin-3 triggered disruption of adhesion plaques, leading to sarcoma cell migration on laminin-111.…”
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For Better or Worse: The Potential for Dose Limiting the On-Target Toxicity of PI 3-Kinase Inhibitors by Christina M. Buchanan, Kate L. Lee, Peter R. Shepherd

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BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance by Zaborski Margarete, Romani Julia, Eberth Sonja, Quentmeier Hilmar, Drexler Hans G

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ANCA vasculitis expands the spectrum of autoimmune manifestations of activated PI3 kinase δ syndrome by Amika K. Sood, Olivia Francis, Stephen A. Schworer, Stephen A. Schworer, Steven M. Johnson, Benjamin D. Smith, Paul B. Googe, Eveline Y. Wu, Eveline Y. Wu

Subjects: “…activated PI3 kinase delta syndrome…”
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Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase. by Hashem A Dbouk, Bassem D Khalil, Haiyan Wu, Aliaksei Shymanets, Bernd Nürnberg, Jonathan M Backer

“…The PI3-kinase pathway is commonly activated in tumors, most often by loss of PTEN lipid phosphatase activity or the amplification or mutation of p110α. …”
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Bioactive PI3-kinase/Akt/mTOR Inhibitors in Targeted Lung Cancer Therapy by Somayyeh Ghareghomi, Vahideh Atabaki, Naseh Abdollahzadeh, Shahin Ahmadian, Salar Hafez Ghoran

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Protease-activated receptor 4 causes Akt phosphorylation independently of PI3 kinase pathways by Carol Dangelmaier, Satya P Kunapuli

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Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. by Britta J Eickholt, Aminul I Ahmed, Meirion Davies, Evangelia A Papakonstanti, Wayne Pearce, Michelle L Starkey, Antonio Bilancio, Anna C Need, Andrew J H Smith, Susan M Hall, Frank P Hamers, Karl P Giese, Elizabeth J Bradbury, Bart Vanhaesebroeck

“…The expression and function of the 8 distinct catalytic isoforms of PI 3-kinase (PI3K) in the nervous system are unknown. …”
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2325 Targeting isoform-specific PI3 kinase signaling for treatment of cutaneous T cell lymphoma by Suravi Raychaudhuri, Chi-Heng Wu, Weiyun Ai

“…RESULTS/ANTICIPATED RESULTS: Previous results from the Ai lab have demonstrated the importance of the PI3 kinase signaling cascade using high-throughput proliferation assays and siRNA knockdown of individual and double PI3 kinase isoforms (unpublished data). …”
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