The impact of financial incentives on HIV incidence among adolescent girls and young women in Eswatini: Sitakhela Likusasa, a cluster randomised trial by David Wilson, Marelize Gorgens, Sosthenes Ketende, Damien de Walque, Gugu Maphalala, Andrew F Longosz, Mbuso Mabuza, Muziwethu Nkambule, Tengetile Dlamini, Kelvin Sikwibele, Vimbai Tsododo, Tendai Chipepera, Mxolisi Leroy Ndikandika, Wendy Heard, Lindiwe Dlamini, Khanya Mabuza

“…Compared with the no intervention subarm, HIV incidence in the raffle and education incentive subarm was significantly lower, 5.79% (54/878) versus 8.84% (80/905); OR: 0.634 (0.443 to 0.907); aOR: 0.622 (0.433 to 0.893), while it was not significantly lower in the raffle incentive subarm.Conclusion Financial incentives conditional on education participation significantly reduced HIV infection among adolescent girls and young women in Eswatini and appear to be a promising tool for prevention in high HIV prevalence settings.Trial registration number Western Institutional Review Board—protocol number 20 141 630.Eswatini National Health Research Review Board—FWA00026661.Pan African Clinical Trials Registry—PACTR201811609257043.…”
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Improved maternal–fetal outcomes among emergency obstetric referrals following phone call communication at a teaching hospital in south western Uganda: a quasi-experimental study by Hamson Kanyesigye, Jerome Kabakyenga, Edgar Mulogo, Yarine Fajardo, Daniel Atwine, Noni E. MacDonald, Robert Bortolussi, Richard Migisha, Joseph Ngonzi

“…Trial registration Pan African Clinical Trial Registry PACTR20200686885039.…”
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Feasibility and effectiveness of self-monitoring of blood glucose among insulin-dependent patients with type 2 diabetes: open randomized control trial in three rural districts in R... by Loise Ng’ang’a, Gedeon Ngoga, Symaque Dusabeyezu, Bethany L. Hedt-Gauthier, Emmanuel Harerimana, Simon Pierre Niyonsenga, Charlotte M. Bavuma, Gene Bukhman, Alma J. Adler, Fredrick Kateera, Paul H. Park

“…Trial registration The trial was registered retrospectively on the Pan African Clinical Trial Registry, on 17th May 2019. …”
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Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): a randomised controlled trial protocol by Shane A Norris, Carl Lombard, Jean Claude Mutabazi, Katherine Murphy, Naomi Levitt, Christina Zarowsky, Tawanda Chivese, Lara R Fairall, Estelle Lambert, Lisa Jayne Ware, Mushi Matjila, Janetta Harbron, Lorrein Shamiso Muhwava

“…Any protocol amendments will be communicated to investigators, Human Ethics Research Committees, trial participants, and trial registries.Trial registration number PAN African Clinical Trials Registry (https://pactr.samrc.ac.za) on 11 June 2018 (identifier PACTR201805003336174).…”
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Theory-based immunisation health education intervention in improving child immunisation uptake among antenatal mothers attending federal medical centre in Nigeria: A study protocol... by Abubakar Nasiru Galadima, Nor Afiah Mohd Zulkefli, Salmiah Md Said, Norliza Ahmad, Saleh Ngaski Garba

“…<h4>Trial registration</h4> Pan African Clinical Trial Registry PACTR202006722055635. …”
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Empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia: study protocol for a multicenter, open-label randomized controlled clini... by Pablo Rojo, Cinta Moraleda, Alfredo Tagarro, Sara Domínguez-Rodríguez, Lola Madrid Castillo, Luis Manuel Prieto Tato, Aranzazu Sancho López, Lilit Manukyan, Olivier Marcy, Valeriane Leroy, Alessandra Nardone, David Burger, Quique Bassat, Matthew Bates, Raoul Moh, Pui-Ying Iroh Tam, Tisungane Mvalo, Justina Magallhaes, W. Chris Buck, Jahit Sacarlal, Victor Musiime, Chishala Chabala, Hilda Angela Mujuru

“…Trial registration ClinicalTrials.gov , NCT03915366, Universal Trial Number U111-1231-4736, Pan African Clinical Trial Registry PACTR201994797961340.…”
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Costs and cost-effectiveness of Shamiri, a brief, layperson-delivered intervention for Kenyan adolescents: a randomized controlled trial by Corinne N. Kacmarek, Natalie E. Johnson, Tom L. Osborn, Christine Wasanga, John R. Weisz, Brian T. Yates

“…Trial registration This study was registered prior to participant enrollment in the Pan-African Clinical Trials Registry (PACTR201906525818462), registered 20 Jun 2019, https://pactr.samrc.ac.za/Search.aspx .…”
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Linking sedimentary provenance, climate and tectonics in the Neoproterozoic Seridó Belt, Borborema Province (NE Brazil) by Carlos V.A. Ribeiro, Marcos C.C. Sales, Armando L.S. de Oliveira, Ricardo Sallet

“…The Seridó Belt, at the extreme northeast of Brazil, is one of the several Neoproterozoic mobile belts related to the Brasiliano/Pan-African Orogeny in Western Gondwana. The lithostratigraphy of the Seridó Belt comprises basal quartzites and metaconglomerates (Equador Formation) overlain by hornblende-bearing paragneisses, calc-silicate rocks and marbles (Jucurutu Formation) and biotite-schists (Seridó Formation). …”
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Changes in serological immunology measures in UK and Kenyan adults post-controlled human malaria infection by Hodgson, S, Llewellyn, D, Silk, S, Milne, K, Elias, S, Miura, K, Kamuyu, G, Juma, E, Magiri, C, Muia, A, Jin, J, Spencer, A, Longley, R, Mercier, T, Decosterd, L, Long, C, Osier, F, Hoffman, S, Ogutu, B, Hill, A, Marsh, K, Draper, S

“…The first Kenyan Challenge Study (KCS) (Pan African Clinical Trial Registry: PACTR20121100033272) was performed in 2013 with the aim of establishing the CHMI model in Kenya. …”

Comparing drug regimens for clearance of malaria parasites in asymptomatic adults using PCR in Kilifi County, Kenya: an open-label randomised controlled clinical trial (MalPaC) by Khaemba, EN, Ogwang, C, Kinyanjui, S, Muindi, JM, Koske, JK, Kimani, D, Ngoi, J, Mwacharo, J, Shangala, J, Njuguna, P, Mutinda, D, Nyatichi, E, Peshu, J, Mutinda, B, Ndungu, FM, Farnert, A, Bashraheil, MM, Bejon, P, Kapulu, MC

“…</p> <p><strong>Trial registration:</strong> Pan African Clinical Trials Registry, 22nd of August 2013, PACTR201309000625311.…”

Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease: Plasma concentrations exceed target levels, with drug accumulation in the most severe patients by Scott, JT, Sharma, R, Meredith, LW, Dunning, J, Moore, CE, Sahr, F, Ward, S, Goodfellow, I, Horby, P

“…</p><br /> <p><strong>Trial registration:</strong><br /> Pan African Clinical Trials Registry PACTR201501000997429.…”

Parenting for lifelong health for young children: a randomized controlled trial of a parenting program in South Africa to prevent harsh parenting and child conduct problems by Ward, CL, Wessels, IM, Lachman, JM, Hutchings, J, Cluver, LD, Kassanjee, R, Nhapi, R, Little, F, Gardner, F

“…Trial registration: ClinicalTrials.gov (NCT02165371); Pan African Clinical Trial Registry (PACTR201402000755243); Violence Prevention Trials Register (http://www.preventviolence.info/Trials?…”

Optimising engagement in a digital parenting intervention to prevent violence against adolescents in Tanzania: protocol for a cluster randomised factorial trial by Janowski, R, Green, O, Shenderovich, Y, Stern, D, Clements, L, Wamoyi, J, Wambura, M, Lachman, JM, Melendez-Torres, GJ, Gardner, F, Baerecke, L, Te Winkel, E, Booij, A, Setton, O, Tsoanyane, S, Mjwara, S, Christine, L, Ornellas, A, Chetty, N, Klapwijk, J, Awah, I, Manjengenja, N, Sokoine, K, Majikata, S, Cluver, LD

“…</p> <p><strong>Trial registration:</strong> Pan African Clinical Trial Registry, PACTR202210657553944. …”

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial by Hamaluba, M, Sang, S, Orindi, B, Njau, I, Karanja, H, Kamau, N, Gitonga, J, Mugo, D, Wright, D, Nyagwange, J, Kutima, B, Omuoyo, D, Mwatasa, M, Ngetsa, C, Agoti, C, Cheruiyot, S, Nyaguara, A, Munene, M, Mturi, N, Oloo, E, Ochola-Oyier, L, Mumba, N, Mauncho, C, Namayi, R, Davies, A, Tsofa, B, Nduati, E, Aliyan, N, Kasera, K, Etyang, A, Boyd, A, Hill, A, Gilbert, S, Douglas, A, Pollard, A, Bejon, P, Lambe, T, Warimwe, G

“…<br><strong> Conclusions: </strong>The safety, immunogenicity and efficacy against asymptomatic infection of ChAdOx1 nCoV-19 among Kenyan adults was similar to that observed elsewhere in the world, but efficacy against symptomatic infection or severe disease could not be measured in this cohort.<br><strong> Pan-African Clinical Trials Registration: </strong>PACTR202005681895696 (11/05/2020)…”

Multi-Trait Selection Index for Simultaneous Selection of Water Yam (<i>Dioscorea alata</i> L.) Genotypes by Fatoumata Ouattara, Paterne A. Agre, Idris I. Adejumobi, Malachy O. Akoroda, Fatogoma Sorho, Koutoua Ayolié, Ranjana Bhattacharjee

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An overview of climate change adaptation and mitigation research in Africa by Yvette Baninla, Yvette Baninla, Ayyoob Sharifi, Zaheer Allam, Suiven John Paul Tume, Ngeh Najibullah Gangtar, Ngiamte George

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A Systematic Review on Suitability of Molecular Techniques for Diagnosis and Research into Infectious Diseases of Concern in Resource-Limited Settings by Akua K. Yalley, Selasie Ahiatrogah, Anna A. Kafintu-Kwashie, Gloria Amegatcher, Diana Prah, Akua K. Botwe, Mildred A. Adusei-Poku, Evangeline Obodai, Nicholas I. Nii-Trebi

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Heterotic grouping of provitamin A-enriched maize inbred lines for increased provitamin A content in hybrids by Abdoul-Raouf Sayadi Maazou, Melaku Gedil, Victor O. Adetimirin, Nnanna Unachukwu, Wende Mengesha, Silvestro Meseka, Abebe Menkir

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Bayesian and Frequentist Approaches for a Tractable Parametric General Class of Hazard-Based Regression Models: An Application to Oncology Data by Abdisalam Hassan Muse, Samuel Mwalili, Oscar Ngesa, Christophe Chesneau, Afrah Al-Bossly, Mahmoud El-Morshedy

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Characterization of Lignocellulosic Biomass Samples in Omu-Aran Metropolis, Kwara State, Nigeria, as Potential Fuel for Pyrolysis Yields by Anthony O Onokwai, Imhade P Okokpujie, Emmanuel S Ajisegiri, Makanjuola Oki, Adeyinka O Adeoyeb, Esther T Akinlabi

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