Viral Myocarditis: Classification, Diagnosis, and Clinical Implications by Fabiola B. Sozzi, Elisa Gherbesi, Andrea Faggiano, Eleonora Gnan, Alessio Maruccio, Marco Schiavone, Laura Iacuzio, Stefano Carugo

“…The absence of specific pathognomonic features in conjunction with the wide spectrum of clinical manifestations that range from subclinical cases to sudden cardiac death (SCD) makes myocarditis diagnosis particularly challenging. …”
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Pre-slaughter, slaughter and post-slaughter practices of slaughterhouse workers in Southeast, Nigeria: Animal welfare, meat quality, food safety and public health implications. by Emmanuel O Njoga, Stanley U Ilo, Obichukwu C Nwobi, Onyinye S Onwumere-Idolor, Festus E Ajibo, Chinwe E Okoli, Ishmael F Jaja, James W Oguttu

“…During the PMI, diseased carcasses/meats/organs were detected in 5.7% (83/1452), 2.1% (21/1006) and 0.8% (7/924) of the cattle, pig and goat carcasses inspected, respectively. Gross lesions pathognomonic of bovine tuberculosis, contagious bovine pleuro-pneumonia, fascioliasis and porcine cysticercosis were detected. …”
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Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3... by Heesun J. Rogers, James W. Vardiman, John Anastasi, Gordana Raca, Natasha M. Savage, Athena M. Cherry, Daniel Arber, Erika Moore, Jennifer JD. Morrissette, Adam Bagg, Yen-Chun Liu, Susan Mathew, Attilio Orazi, Pei Lin, Sa A. Wang, Carlos E. Bueso-Ramos, Kathryn Foucar, Robert P. Hasserjian, Ramon V. Tiu, Matthew Karafa, Eric D. Hsi

“…However, inv(3)(q21q26.2)/t(3;3)(q21;q26.2) is not among the cytogenetic abnormalities pathognomonic for diagnosis of acute myeloid leukemia irrespective of blast percentage in the 2008 WHO classification. …”
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FISH-negative BCR::ABL1-positive e19a2 chronic myeloid leukaemia: the most cryptic of insertions by Philippa C. May, Alistair G. Reid, Mark E. Robinson, Jamshid S. Khorashad, Dragana Milojkovic, Simone Claudiani, Genomics England Research Consortium, Fenella Willis, Jane F. Apperley, Andrew J. Innes

“…Most patients have a cytogenetically visible translocation between chromosomes 9 and 22 which generates the pathognomonic BCR::ABL1 fusion gene. The derivative chromosome 22 (‘Philadelphia’ or Ph chromosome) usually harbours the fusion gene encoding a constitutively active ABL1 kinase domain. …”
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Evaluation of new Toxocara canis chimeric antigens as an alternative to conventional TES-Ag for anti-Toxocara antibodies detection by Jairo A. Mesa-Arango, Ana M. Olave-Velandia, Gisela M. García-Montoya, Juan P. Isaza-Agudelo, Antonio Jiménez-Ruiz, Juan F. Alzate

“…Notwithstanding, due to the absence of pathognomonic symptoms and signs of the disease, serology is the key evidence to support a conclusive diagnosis. …”
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Alterações microscópicas na erupção do Sarampo Histology of measles eruption by C. Magarinos Torres

“…Parakeratotic cells with intranuclear bodies first described by TORRES & TEIXIERA (1932 b) while inconstant are regarded as a pathognomonic change in measles eruption. Edema of the papillary layer and perivascular infiltrations in the reticular layer by large mononuclears some of them containing small irregular deeply stained granules (MALLORY-MEDLAR-LIPSCHÜTZ' cells) are well known changes largely referred in the literature. …”
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Suppression of Lung Adenocarcinoma Progression by Nkx2-1 by Winslow, Monte Meier, Dayton, Talya Lucia, Kim-Kiselak, Caroline, Snyder, Eric, Feldser, David M., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie M., Crowley, Denise G., Verhaak, Roel G., Hubbard, Diana D., Chiang, Derek Y., Myerson, Matthew, Bronson, Roderick T., Jacks, Tyler E

“…In this mouse model, Nkx2-1 negativity is pathognomonic of high-grade poorly differentiated tumours. …”
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MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation by Jennifer Crow, Glenson Samuel, Emily Farrow, Margaret Gibson, Jefferey Johnston, Erin Guest, Neil Miller, Dong Pei, Devin Koestler, Harsh Pathak, Xiaobo Liang, Cooper Mangels, Andrew K Godwin

“…Over 90% of Ewing Sarcoma (ES) tumors are driven by the pathognomonic EWS-ETS chimeric transcripts and their corresponding oncoproteins. …”
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The importance of rapid strep test for acute tonsillopharyngitis in children with pharyngeal deposits by S.A. Tsar’kova, A.S. Sokolova, V.P. Vavilova

“…In 8.9% of children under 3 years of age, acute tonsillopharyngitis was caused by group A </i>β<i>-hemolytic streptococcus (group A strep). No pathognomonic signs of acute tonsillopharyngitis caused by group A strep were revealed. …”
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Clinical feasibility of miniaturized Lissajous scanning confocal laser endomicroscopy for indocyanine green-enhanced brain tumor diagnosis by Duk Hyun Hong, Jang Hun Kim, Jae-Kyung Won, Hyungsin Kim, Chayeon Kim, Kyung-Jae Park, Kyungmin Hwang, Ki-Hun Jeong, Shin-Hyuk Kang

“…In human tissue specimens, CLE images effectively visualized the cytoarchitecture of the normal brain and tumors. In addition, pathognomonic microstructures according to tumor subtype were also clearly observed. …”
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Pathological high frequency oscillations associate with increased GABA synaptic activity in pediatric epilepsy surgery patients by Carlos Cepeda, Simon Levinson, Hiroki Nariai, Vannah-Wila Yazon, Conny Tran, Joshua Barry, Katerina D. Oikonomou, Harry V. Vinters, Aria Fallah, Gary W. Mathern, Joyce Y. Wu

“…Pathological high-frequency oscillations (HFOs), specifically fast ripples (FRs, >250 Hz), are pathognomonic of an active epileptogenic zone. However, the origin of FRs remains unknown. …”
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Novel characteristics for immunophenotype, FISH pattern and molecular cytogenetics in synovial sarcoma by Ling ling Zhong, Gao xiang Huang, Li ying Xian, Zong chen Wei, Zhi ping Tang, Qiu yue Chen, Hao Chen, Fang Tang

“…Abstract As a rare and highly aggressive soft tissue sarcoma, the new immunophenotype, atypical FISH pattern and relevant molecular cytogenetics of synovial sarcoma (SS) remain less known, although it is characteristically represented by a pathognomonic chromosomal translocation t (X; 18) (p11.2; q11.2). …”
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Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome by Jibril B. Hirbo, Francesca Pasutto, Eric R. Gamazon, Patrick Evans, Priyanka Pawar, Daniel Berner, Julia Sealock, Ran Tao, Peter S. Straub, Anuar I. Konkashbaev, Max A. Breyer, Ursula Schlötzer-Schrehardt, André Reis, Milam A. Brantley, Chiea C. Khor, Karen M. Joos, Nancy J. Cox

“…Abstract Background Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause of secondary glaucoma, resulting in widespread global blindness. …”
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Contemporary review on spontaneous coronary artery dissection: insights into the angiographic finding and differential diagnosis by M. Kovacevic, M. Kovacevic, M. Jarakovic, M. Jarakovic, A. Milovancev, A. Milovancev, M. Cankovic, M. Cankovic, M. Petrovic, M. Petrovic, M. Bjelobrk, M. Bjelobrk, A. Ilic, A. Ilic, I. Srdanovic, I. Srdanovic, S. Tadic, S. Tadic, D. Dabovic, D. Dabovic, B. Crnomarkovic, N. Komazec, N. Dracina, S. Apostolovic, S. Apostolovic, D. Stanojevic, V. Kunadian, V. Kunadian

“…Finally, apart from the pathognomonic angiographic features of SCAD that are thoroughly discussed in this review, the authors focus on obscure angiography findings and findings that can mimic SCAD as well. …”
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Loss of MYO5B in Mice Recapitulates Microvillus Inclusion Disease and Reveals an Apical Trafficking Pathway Distinct to Neonatal DuodenumSummary by Victoria G. Weis, Byron C. Knowles, Eunyoung Choi, Anna E. Goldstein, Janice A. Williams, Elizabeth H. Manning, Joseph T. Roland, Lynne A. Lapierre, James R. Goldenring

“…Loss of active MYO5B causes the formation of pathognomonic inclusions and aberrations in brush-border enzymes. …”
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Human periventricular nodular heterotopia shows several interictal epileptic patterns and hyperexcitability of neuronal firing by Valerio Frazzini, Valerio Frazzini, Stephen Whitmarsh, Katia Lehongre, Pierre Yger, Jean-Didier Lemarechal, Jean-Didier Lemarechal, Bertrand Mathon, Bertrand Mathon, Claude Adam, Dominique Hasboun, Dominique Hasboun, Virginie Lambrecq, Virginie Lambrecq, Vincent Navarro, Vincent Navarro

“…Together, nodules in PNH are highly epileptogenic and show several IPs that provide promising pathognomonic signatures of PNH. Furthermore, our results show that PNH nodules may well initiate seizures.…”
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Non-Wilms renal tumors: Twenty years experience in a referral center by Cristina Garcés-Visier, Przemyslaw Maruszewski, Ana Lourdes Luis-Huertas, Pedro Borrrego-Jimenez, Daniel Azorín, Alberto Martín-Vega, Manuel Espinoza-Vega, Blanca Herrero-Velasco, Jose Lorenzo Alonso-Calderón

“…However, there are no pathognomonic imaging findings that clearly differentiate between WT and other renal tumors, nor among the heterogeneous group of NWRT[3]. …”
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Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…No behavioral symptom is pathognomonic of a specific proteinopathy; rather, the topography and severity of lesions plays a more decisive role than their single molecular composition.Systematic review registrationINPLASY2024100082.…”
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Clinical Characteristics and Outcomes of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder With Brainstem Lesions as Heralding Prodrome by Qiling Ji, Huiqing Dong, Hangil Lee, Zheng Liu, Yanna Tong, Kenneth Elkin, Yazeed Haddad, Xiaokun Geng, Xiaokun Geng, Yuchuan Ding

“…Additionally, distinct imaging manifestations such as lesion location(s) and morphology may also aid in the development of pathognomonic criteria leading to timely initial diagnosis of MS and NMOSD.…”
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Pathological, microscopic, and molecular diagnosis of paratuberculosis/John’s disease in naturally infected dromedary camel (Camelus dromedarius) by El Tigani Ahmed El Tigani-Asil, Ghada El Derdiri Abdelwahab, El Hadi Ahmed Mohamed Abdu, Abdelnasir Mohammed Adam Terab, Nasareldien Altaib Hussein Khalil, Zhaya Jaber Mohammed Al Marri, Mohd Farouk Yuosf, Asma Abdi Mohamed Shah, Abdelmalik Ibrahim Khalafalla, Hassan Zackaria Ali Ishag

“…Results: Clinically, typical clinical signs compliant with the pathognomonic gross and histologic lesions of PTB were seen in naturally infected dromedary camel. …”
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