Image-based quantification of histological features as a function of spatial location using the Tissue Positioning SystemResearch in context by Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang

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Ambulatory systolic blood pressure and obesity are independently associated with left ventricular hypertrophic remodeling in children by Linyuan Jing, Christopher D. Nevius, Cassi M. Friday, Jonathan D. Suever, Arichanah Pulenthiran, Abba Mejia-Spiegeler, H. Lester Kirchner, William J. Cochran, Gregory J. Wehner, Aftab S. Chishti, Christopher M. Haggerty, Brandon K. Fornwalt

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Hydrolyzed rice formula for dietary management of infants with cow's milk allergy by Alessandro Fiocchi, MD, Josefa Barrio-Torres, MD, PhD, Christophe Dupont, MD, PhD, Helen Evans Howells, MD, MSc, Raanan Shamir, MD, PhD, Carina Venter, PhD, RD, Rosan Meyer, B.Diet, M.Nutr, PhD

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Whole Goat Milk-Based Formula versus Whey-Based Cow Milk Formula: What Formula Do Infants Enjoy More?—A Feasibility, Double-Blind, Randomized Controlled Trial by Camille Jung, Adolfo González Serrano, Christophe Batard, Elisa Seror, Georges Gelwane, Amélie Poidvin, Isabelle Lavallée, Annie Elbez, Maxime Brussieux, Colin Prosser, Sophie Gallier, Marc Bellaïche

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Molecular Background, Clinical Features and Management of Pediatric Mastocytosis: Status 2021 by Magdalena Lange, Karin Hartmann, Melody C. Carter, Frank Siebenhaar, Ivan Alvarez-Twose, Inés Torrado, Knut Brockow, Joanna Renke, Ninela Irga-Jaworska, Katarzyna Plata-Nazar, Hanna Ługowska-Umer, Justyna Czarny, Anna Belloni Fortina, Francesca Caroppo, Roman J. Nowicki, Bogusław Nedoszytko, Marek Niedoszytko, Peter Valent

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Clustering of Dietary Patterns and Lifestyles Among Spanish Children in the EsNuPI Study ^† by Julio Plaza-Díaz, Esther Molina-Montes, María José Soto-Méndez, Casandra Madrigal, Ángela Hernández-Ruiz, Teresa Valero, Federico Lara Villoslada, Rosaura Leis, Emilio Martínez de Victoria, José Manuel Moreno, Rosa M. Ortega, María Dolores Ruiz-López, Gregorio Varela-Moreiras, Ángel Gil

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The gastrointestinal antibiotic resistome in pediatric leukemia and lymphoma patients by Tamara MacDonald, Tamara MacDonald, Katherine A. Dunn, Katherine A. Dunn, Katherine A. Dunn, Jane MacDonald, Jane MacDonald, Morgan G.I. Langille, Johan E. Van Limbergen, Johan E. Van Limbergen, Joseph P. Bielawski, Joseph P. Bielawski, Joseph P. Bielawski, Ketan Kulkarni

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Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor by Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz

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Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4 by Daniel H. Leung, Stefan Wirth, Betty B. Yao, Rolando M. Viani, Regino P. Gonzalez‐Peralta, Maureen M. Jonas, Steven J. Lobritto, Michael R. Narkewicz, Etienne Sokal, Clàudia Fortuny, Evelyn K. Hsu, Antonio Del Valle‐Segarra, Jiuhong Zha, Lois Larsen, Li Liu, Diana L. Shuster, Daniel E. Cohen, Philip Rosenthal

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Changes in the Prevalence of Coccidian Protozoa in Immunocompromised Patients Over the Last Decade by Özlem ULUSAN BAĞCI, Orçun ZORBOZAN, Kardelen YETİŞMİŞ, Sema AYDOĞDU, Fatma Ömür ARDENİZ, Ayşe Deniz GÖKENGİN, Mehmet KANTAR, Eren SOYALTIN, Önder YAVAŞCAN, Fehmi AKÇİÇEK, Nevin TURGAY

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Favorable outcome of empagliflozin treatment in two pediatric glycogen storage disease type 1b patients by Zufit Hexner-Erlichman, Zufit Hexner-Erlichman, Maria Veiga-da-Cunha, Yoav Zehavi, Yoav Zehavi, Yoav Zehavi, Zahava Vadasz, Zahava Vadasz, Adi D. Sabag, Sameh Tatour, Ronen Spiegel, Ronen Spiegel, Ronen Spiegel

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Translation, cultural adaptation, and validation of the celiac disease DUX (CDDUX) by Manuela Torres Camara Lins, Rafael Miranda Tassitano, Kátia Galeão Brandt, Margarida Maria de Castro Antunes, Giselia Alves Pontes da Silva

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Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study by Kathleen M. Loomes, Robert H. Squires, Deirdre Kelly, Sanjay Rajwal, Nisreen Soufi, Alain Lachaux, Irena Jankowska, Cara Mack, Kenneth D. R. Setchell, Palaniswamy Karthikeyan, Ciara Kennedy, Alejandro Dorenbaum, Nirav K. Desai, Will Garner, Thomas Jaecklin, Pamela Vig, Alexander Miethke, Richard J. Thompson

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Celiac Disease in Uzbek Children: Insights into Disease Prevalence and Clinical Characteristics in Symptomatic Pediatric Patients by Altinoy T. Kamilova, Gulnoza K. Azizova, Dimitri Poddighe, Zulkhumar E. Umarnazarova, Dilrabo A. Abdullaeva, Svetlana I. Geller, Noiba D. Azimova

“…Methods: This is a prospective and cross-sectional study investigating the prevalence and clinical characteristics of CD in symptomatic children referred to the pediatric gastroenterology department of a tertiary hospital in Uzbekistan from 1 September 2021, until 31 July 2022. …”
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Dietary Intake, Nutritional Adequacy, and Food Sources of Protein and Relationships with Personal and Family Factors in Spanish Children Aged One to <10 Years: Findings of the EsNu... by Casandra Madrigal, María José Soto-Méndez, Ángela Hernández-Ruiz, Teresa Valero, Federico Lara Villoslada, Rosaura Leis, Emilio Martínez de Victoria, José Manuel Moreno, Rosa M. Ortega, María Dolores Ruiz-López, Gregorio Varela-Moreiras, Ángel Gil

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Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES) by Meng-Ying Hsieh, Jainn-Jim Lin, Shao-Hsuan Hsia, Jing-Long Huang, Kuo-Wei Yeh, Kuei-Wen Chang, Wen-I. Lee

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Assessment of Real-World Patient-Reported Outcomes in Patients Initiating Biologic Agents for the Treatment of Autoimmune Diseases: An Observational Study in Four Patient-Powered R... by Beukelman T, Long MD, Rhee RL, Kappelman MD, Merkel PA, Nowell WB, Clinton C, Ringold S, Del Gaizo V, Price B, Shaw DG, Venkatachalam S, Cuthbertson D, Xie F, Zhang X, Curtis JR

“…Timothy Beukelman,1 Millie D Long,2 Rennie L Rhee,3 Michael D Kappelman,4 Peter A Merkel,3,5 William Benjamin Nowell,6 Cassie Clinton,7 Sarah Ringold,8 Vincent Del Gaizo,9 Brian Price,10 Dianne G Shaw,11 Shilpa Venkatachalam,6 David Cuthbertson,12 Fenglong Xie,7 Xian Zhang,4 Jeffrey R Curtis7 1Department of Pediatrics, Division of Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; 2Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 3Department of Medicine, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, USA; 4Department of Pediatrics, Division of Pediatric Gastroenterology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 5Department of Biostatistics, Epidemiology, and Informatics; Division of Epidemiology, University of Pennsylvania, Philadelphia, PA, USA; 6Global Healthy Living Foundation, Upper Nyack, NY, USA; 7Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; 8Department of Pediatrics, Division of Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA; 9Childhood Arthritis and Rheumatology Research Alliance (CARRA) and PARTNERS PPRN, Milwaukee, WI, USA; 10Crohn’s and Colitis Foundation and IBD-Partners, New York, NY, USA; 11Vasculitis Patient Powered Research Network, Kansas City, MO, USA; 12Health Informatics Institute, University of South Florida, Tampa, FL, USACorrespondence: Timothy Beukelman, Email timbeukelman@uabmc.eduBackground: The most reliable and meaningful approach for inclusion of patient-reported outcomes (PROs) in the evaluation of real-world clinical effectiveness of biologics in the treatment of autoimmune diseases is u ncertain. …”
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Protein structural insights into a rare PCSK9 gain-of-function variant (R496W) causing familial hypercholesterolemia in a Saudi family: whole exome sequencing and computational ana... by Noor Ahmad Shaik, Noor Ahmad Shaik, Najla Al-Shehri, Mohammad Athar, Mohammad Athar, Ahmed Awan, Mariam Khalili, Hadiah Bassam Al Mahadi, Gehan Hejazy, Omar I. Saadah, Sameer Eida Al-Harthi, Ramu Elango, Ramu Elango, Babajan Banaganapalli, Babajan Banaganapalli, Eman Alefishat, Eman Alefishat, Eman Alefishat, Zuhier Awan

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Elbasvir/grazoprevir in children aged 3–18 years with chronic HCV genotype 1 or 4 infection: a pharmacokinetic modeling study by Regino P. Gonzalez-Peralta, Stefan Wirth, Robert H. Squires, Frauke Mutschler, Thomas Lang, Malgorzata Pawlowska, Wojciech Sluzewski, Ewa Majda-Stanislawska, Bjorn Fischler, William F. Balistreri, Maureen M. Jonas, Niviann Blondet, Philip Rosenthal, Naim Alkhouri, Rene Romero, Anjana Grandhi, Patricia Castronuovo, Luzelena Caro, Lihong Du, Daniel I.S. Rosenbloom, Barbara A. Haber

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Diagnostic action against hypertransaminasemia in paediatrics: Consensus document of Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica (SEGHNP), Asociación... by Ignacio Ros Arnal, Joaquín Reyes Andrade, María Mercadal Hally, Luis Carlos Blesa Baviera, Diana García Tirado, Samuel Héctor Campuzano Martín, Estela de la Calle Navarro, Ana María Vegas Álvarez

“…To this end, a working group was formed with the participation of members of the Society of Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP), the Spanish Association of Primary Care Pediatrics (AEPap) and the Spanish Society of Primary Care Pediatrics (SEPEAP). …”
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