Early intervention in psoriasis: Where do we go from here? by Paulo Antônio Oldani Felix, Ana Luisa Sampaio, Bruno Leonardo Silva, Analia Luiza Porto Viana

“…Ideally, randomized trials would be the best strategy to compare early vs. late systemic treatment in patients with psoriasis, probably using the frequency of long-term outcomes as primary endpoint, with cutaneous and pharmacoeconomic outcomes assessed secondarily.…”
Get full text

An Analysis of the Results of the Euro Health Consumer Index from 2014 to 2017 with Special Reference to Prevention Indicators by Boris Lukovnjak

“…It is also important to mention that the poor results of prevention-based activities have a strong pharmacoeconomic impact; it is widely known that one kuna invested in prevention and primary healthcare is equivalent to 10 kunas invested in hospital treatment.…”
Get full text

ADVANTAGES OF BROAD SPECTRUM ANTIEPILEPTIC DRUGS IN TREATMENT OF EPILEPSY by K. V. Voronkova, G. S. Golosnaya, I. D. Lemeshko, A. S. Petrukhin

“…Pharmacotherapy of epilepsy requires deep knowledge  of anti-epileptic drugs (AEDs), including the following issues: spectrum of therapeutic efficacy and therapeutic strength, adverse effects (especially severe and life-threatening adverse reactions); specific features of pharmacokinetics,  pharmacodynamics, and drug interactions; titration rate, the need for laboratory tests  during treatment,  pharmacoeconomic components.  The main properties  of antiepileptic drugs  are defined by their mechanisms of action. …”
Get full text

Overview of mathematical models of breast cancer by Yu. P. Yurkova, A. A. Kurylev, A. S. Kolbin

“…Not included publications could be divided into groups: pharmacoeconomic model of particular drug, BC screening models, model of tumor growth, models of ВС imaging (US, MRI).Results. …”
Get full text

Trained Immunity Based-Vaccines as a Prophylactic Strategy in Common Variable Immunodeficiency. A Proof of Concept Study by Kissy Guevara-Hoyer, Paula Saz-Leal, Carmen M. Diez-Rivero, Juliana Ochoa-Grullón, Miguel Fernández-Arquero, Rebeca Pérez de Diego, Silvia Sánchez-Ramón

“…We analyzed the pharmacoeconomic impact on the RRTI group before and after immunotherapy by estimating the direct and indirect costs, and assessed CVID-QoL and cytokine profile. …”
Get full text

Prevalence, patterns and predictors of depression treatment among community-dwelling older adults with stroke in the United States: a cross sectional study by Sandipan Bhattacharjee, Majed Al Yami, Sawsan Kurdi, David Rhys Axon

Get full text

Real-World Evidence Studies of Oritavancin Use in Gram-Positive Infections Augment Randomized Controlled Trials to Address Clinical and Economic Outcomes by Mark Redell

“…Lastly, RCTs do not include pharmacoeconomic data that would add a cost basis for determining the value of one product over another. …”
Get full text

Capecitabine in the management of colorectal cancer by Hirsch BR, Zafar SY

“…In a setting of increasing focus on cost, the pharmacoeconomic literature is also briefly reviewed.Keywords: colon cancer, colorectal cancer, rectal cancer, capecitabine, Xeloda…”
Get full text

Editorial: Recent advances in attempts to improve medication adherence-from basic research to clinical practice by Przemyslaw Kardas, Alexandra L. Dima, Alexandra L. Dima, Ines Potočnjak, Bjorn Wettermark, Bjorn Wettermark, Tamas Agh, Tamas Agh

Get full text

Potential Immune-Related Adverse Events Associated With Monotherapy and Combination Therapy of Ipilimumab, Nivolumab, and Pembrolizumab for Advanced Melanoma: A Systematic Review a... by Abdulaali R. Almutairi, Abdulaali R. Almutairi, Ali McBride, Ali McBride, Marion Slack, Brian L. Erstad, Ivo Abraham, Ivo Abraham, Ivo Abraham

Get full text

Cost-minimization analysis of oral and intravenous administration of linezolid in a public hospital in southern Brazil by Érika Taguti, Edson Antonio Alves da Silva, Andréia Cristina Conegero Sanches

“…The cost savings associated with switching to oral linezolid administration would be US$14,328.32 over four years. Pharmacoeconomic analyses of linezolid therapy can inform hospitals’ decisions about the rational use of therapeutics and economic resources.…”
Get full text

THE STUDY ON THE MEDICAL ADHERENCE OF PATIENTS TO RHEUMATOID ARTHRITIS TREATMENT by Mihaela-Simona SUBTIRELU, Adina TURCU-STIOLICA, Florin-Ananu VREJU, Johny NEAMTU

“…In order to assess the correct adherence, it is necessary to start using pharmacoeconomic instruments such as CQR-19, DAS, Morisky scale etc. …”
Get full text

Profilo farmacologico clinico e farmacoeconomico di un gel oftalmico a base di carbomero 974P e PVA (Siccafluid®) nella terapia della cheratocongiuntivite secca by Lorenzo Pradelli, Letizia Vacchini

“…METHODS: In the first step of our work we reviewed the data from literature reporting about carbomers’ characteristics in respect to other lacrimal substitutes. Then, a pharmacoeconomical analysis has been performed on ophtalmic gels derived from carbomers 974P and PVA. …”
Get full text

Big peptide drugs in a small molecule world by Laszlo Otvos, Laszlo Otvos, John D. Wade, John D. Wade

“…Unfortunately, however, pharmacoeconomical considerations, including the strength of big pharma to develop competing small molecule drugs, have somewhat limited the success of otherwise smart peptide-based therapeutics. …”
Get full text

Current Therapeutic Strategies for Metastatic Triple-Negative Breast Cancer: From Pharmacists’ Perspective by Shuanghe Li, Chongyang Bao, Lingli Huang, Ji-Fu Wei

“…Pharmacists can play an important role in drug selection, drug therapy management, the management of adverse drug reactions and pharmacoeconomic evaluation. In this review, we summarized traditional treatment strategies, and discussed the efficacy and safety of novel agents approved in the last ten years and combination regimens for mTNBC, with the aim of providing management strategies for the clinical management of mTNBC from pharmacists’ perspective.…”
Get full text

Clinical and economic profile of entecavir in the treatment of chronic hepatitis b virus infection by Mario Eandi

“…If compared, through pharmacoeconomic models and analysis, to tenofovir, a nucleotide acid considered equivalent in the first-line monotherapy of HBeAg-positive patients and in the long-term treatment of HBeAg-negative patients by the current international and Italian guidelines, it seems favourable in terms of safety and consequently in terms of costs of adverse events spared. …”
Get full text

TREATMENT FOR THE UROGENITAL DISORDERS, CAUSED BY THE ESTROGEN DEFICIENCY by V. N. Serov

“…We also described all the pharmacoeconomic properties of the Ovestin and the beneficial effect the local application of estriol has on a married couple.…”
Get full text

Combined Therapy of Arterial Hypertension. The Opinion of a Clinical Pharmacologist by M. V. Zhuravleva, E. V. Luchinina, T. V. Shelekhova, S. Yu. Serebrova, S. A. Belkov, A. I. Dmitriev, G. I. Gorodetskaya

“…The combination of lisinopril with amlodipine not only proved its high efficiency in various international and Russian studies, but also turned out to be pharmacoeconomically more profitable. Fixed combinations of lisinopril and amlodipine are the optimal choice in the treatment of hypertensive patients, due to all the advantages of both components: higher efficacy and safety rates compared to monotherapy and better patient adherence to treatment.…”
Get full text

Real world evidence (RWE) - Are we (RWE) ready? by Viraj Ramesh Suvarna

“…Nevertheless, comparative effectiveness research in the real world is being resorted to, especially for efficiency studies or pharmacoeconomic analyses, and with the advent of machine learning, the electronic healthcare database mining can result in algorithms that help doctors identify clinical characteristics that correlate with optimal response of a patient to a drug/regimen, thus helping him/her select the right patient for the right drug.…”
Get full text

Efficiency of vaccine prophylaxis concentrated pneumococcal vaccine in patients with chronic obstructive lung disease and chronic heart failure by G L Ignatova, V N Antonov

“…The article uses the analysis of clinical and pharmacoeconomic effectiveness of 13-valent conjugated pneumococcal vaccine in patients with combined course of chronic obstructive pulmonary disease (COPD), ischemic heart disease (IHD) and chronic heart failure (CHF). …”
Get full text