Comparative study for the efficacy, safety and quality of life in patients of chronic myeloid leukemia treated with Imatinib or Hydroxyurea by Parveen Jain, V. N. R. Das, Alok Ranjan, Rahul Chaudhary, Krishna Pandey

“…Even with such better efficacy and safety profile, pharmacoeconomic evaluation needs to be done to justify and support the use of imatinib for CML patients in India.…”
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Orphan drugs : future viability of current forecasting models, in light of impending changes to influential market factors by Gottlieb, Joshua

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Economic analysis of allogeneic hematopoietic stem cell transplantation in the Bone Marrow Transplant Center of Tunisia by Leila Achour, Chema Drira, Mohamed Zied Sboui, Ikram Fazaa, Mohamed Ali Soussi, Senda Hammami, Tarek Ben Othman, Myriam Razgallah Khrouf

“…Therefore, an updated cost analysis is needed.Objective: Analysis of direct costs during the first-year post-allogeneic HSCT in two groups of patients: Bone Marrow Transplant (Allo-BMT) and Peripheral Blood Stem Cell Transplant (Allo-PBSCT) and identification of factors leading to interindividual variations in costs in order to compare these costs with the budget allocated by the payer (CNAM).Methods: Pharmacoeconomic retrospective study, concerning patients who underwent allogeneic HSCT in 2013. …”
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Drugs with the highest drug expenditure in the Republic of Serbia by Milijašević Boris Ž., Milak Anđela D., Ubavić Milan B., Krtinić Dane A., Nedin-Ranković Gorana G., Jovanović Hristina M., Trajković Hristina S., Milijašević Dragana S., Popović Radmila N., Todorović Nemanja B., Lalić-Popović Mladena N., Vukosav Nikola B., Baljak Branko M., Tošić Milan S., Matijević Radmila N.

“…On the basis of pharmacoeconomic analyses, it is possible to modify established prescribing habits, it is possible to influence the creation of guidelines, development strategy and long-term health care planning. …”
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Prescribing knowledge in the light of undergraduate clinical pharmacology and therapeutics teaching in India: views of first-year postgraduate students by Upadhyaya P, Seth V, Sharma M, Ahmad M, Moghe VV, Khan ZY, Gupta VK, Jain SV, Soni U, Bhatia M, Abhijit K, Goyal J

“…Their suggestions for improving teaching methods were recorded.Conclusions: This study concludes that efforts are needed to develop a curriculum that encompasses important aspects of clinical pharmacology and therapeutics along with incorporation of the useful suggestions given by the residents.Keywords: clinical pharmacology and therapeutics, medical education, prescription writing, undergraduate medical curriculum, pharmacovigilance, pharmacoeconomics…”
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Valutazione economica dello studio MIRACL by Simona De Portu, Sabato Montella, Simona Cammarota, Lorenzo G. Mantovani

“…Aim: the goal of this pharmacoeconomic study is to evaluate the MIRACL study in the Italian context. …”
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Socio-economic burden of chronic migraine in Russia by A. A. Kolbin, M. V. Naprienko, A. R. Artemenko, I. A. Vilyum, N. V. Latysheva, M. A. Proskurin, Yu. Ye. Balykina

“…Te following types of pharmacoeconomic analyses were used: disease cost analysis, budget effect analysis. …”
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Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multic... by Hong Wang, Chongyang Duan, Jianmin Zhang, Shuangquan Qu, Ying Sun, Lizhi Zhou, Lujia Yang, Chen Lan, Weidong Mi, Pingyan Chen

“…The secondary endpoints include the time of first use of rescue analgesics after surgery, rescue analgesia rate within 48 h after surgery, anesthesia recovery time, incidence of emergency delirium (for 0-7 years old), changes of anxiety and depression scale scores at 48 h after surgery (for 8-17 years old), incidence of intraoperative adverse events (AEs), and incidence of postoperative AEs and pharmacoeconomic indicators. AEs and serious AEs were recorded to evaluate safety. …”
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Efficacy and Safety Data of Subsequent Entry Biologics Pertinent to Nephrology Practice: A Systematic Review by Judith Genevieve Marin, Marianna Leung, Clifford Lo, Nicole W Tsao, Daniel J Martinusen

“…Although not deemed clinically important, the financial implication of a possible dose difference between epoetin zeta and reference product should be considered in pharmacoeconomic studies. Ongoing trials are expected to address the risk of pure-red-cell aplasia with HX 575.…”
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Cost analysis of botulinum therapy of spastic forms of cerebral palsy in Ukraine by S. O. Soloviov, O. V. Nazar, M. V. Leleka

“…Possible variability in the dosage and frequency of administration of onabotolutoxin per year indicates the relevance of collecting additional information on the application in real clinical practice and further pharmacoeconomic studies.…”
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Systematic review of health state utility values in metastatic non-small cell lung cancer with a focus on previously treated patients by Noman Paracha, Ahmed Abdulla, Katherine S. MacGilchrist

“…The EQ-5D website, the School of Health and Related Research Health Utilities Database (ScHARRHUD) and major pharmacoeconomic and clinical conferences in 2015–2016 were also queried. …”
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NEW APPROACHES TO THERAPY OF CLASSICAL PH-NEGATIVE MYELOPROLIFERATIVE DISEASES: THE EXPERIENCE OF EARLY THERAPY WITH CEPEGINTERFERON ALPHA-2B by A. S. Polyakov, Y. A. Noskov, V. V. Tyrenko, A. S. Lapshova, A. V. Kovalev

“…CePEGIFN alpha-2b showed less dose-limiting toxicity for neutropenia and better pharmacoeconomic feasibility.Discussion. New data about mechanisms of antiproliferative effects of interferon alfa preparations are given. …”
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Lapatinib in patients with metastatic breast cancer following initial treatment with trastuzumab: an economic analysis from the Brazilian public health care perspective by Machado M, Einarson TR

“…Both costs and outcomes were discounted at a 5% rate, in accordance with Brazilian pharmacoeconomic guidelines. Clinical inputs were determined using indirect treatment comparisons. …”
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Efficacy of Leuprorelin 3-Month Depot (11.25 mg) Compared to 1-Month Depot (3.75 mg) for Central Precocious Puberty in Chinese Girls: A Prospective Cohort Study by Jianmei Yang, Qijun Song, Shuo Gao, Yuye Gao, Xiaohong Shang, Guimei Li, Yan Sun, Xiaoping Luo

“…Bone age, serum endocrine hormones, maximum diameter of uterus and volume of ovary of each patient were evaluated. A pharmacoeconomic evaluation was also conducted. Results. …”
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Comparative evaluation of economic effi ciency of modern inhaled anesthetics by D. Yu. Belousov, E. V. Afanasyeva, E. A. Efremova

“…Formalization and evaluation were carried out in accordance with the industry standard “Health technology assessment”, approved and signed into law June 14, 2014 by Order of the Federal Agency for Technical Regulation and Metrology of the Russian Federation GOST №568-art and ISPOR recommendations, and meet the requirements of statistical significance, allowing to develop recommendation conclusions on the use of each product in any given situation. Pharmacoeconomic evaluation is based on data from official registration licenses and patient information leaflets, randomized controlled clinical trials data and information on value, pricing and costs obtained from the public independent sources. …”
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Adherence to fingolimod in multiple sclerosis: an investigator-initiated, prospective, observational, single-center cohort study by Zimmer A, Coslovsky M, Abraham I, Décard BF

“…Andrea Zimmer,1 Michael Coslovsky,2 Ivo Abraham,3 Bernhard F Décard1 1Neurologic Clinic and Policlinic, Department of Medicine, University Hospital Basel, University of Basel, Basel, 2Clinical Trial Unit, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; 3Center for Health Outcomes and Pharmacoeconomic Research, University of Arizona, Tuscon, AZ, USA Objectives: Adherence to multiple sclerosis (MS) treatment is essential to optimize the likelihood of full treatment effect. …”
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Monitoring Cardiovascular Medicine Prices as a Tool for Analyzing the Effectiveness of Government Intervetions to Ensure Access to Medicines at the Regional Level by C. M. Razzakova, L. E. Ziganshina

“…Also we studied the affordability of medicines, as well as performed pharmacoeconomic cost-minimization analysis for arterial hypertension pharmacotherapy in 2018. …”
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Determining the association of perceived health status among united states older adults with self-reported pain by David R. Axon, Amy Jang, Linda Son, Trang Pham

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Detectability and acceptability of continuous pulse signals for the MemoPatch® device, an electronic skin patch intended to deliver tactile medication reminder signals by Abraham I, De Geest J, De Geest W, De Troy E, MacDonald K

“…Ivo Abraham,1–3 Jan De Geest,2 Wim De Geest,2 Elke De Troy,4 Karen MacDonald3 1Center for Health Outcomes and PharmacoEconomic Research, University of Arizona, Tucson, AZ, USA; 2TheraSolve, Diepenbeek, Belgium; 3Matrix45, Tucson, AZ, USA; 4Jessa Ziekenhuis, Hasselt, Belgium Background: Unintended forgetfulness is the most common cause of medication nonadherence. …”
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Pharmacoepidemiological analysis of type 1 diabetes mellitus insulin therapy (According to the Moscow segment of the State Register of Diabetes Mellitus) by M. B. Antsiferov, M. A. Kantemirova, N. A. Demidov, M. F. Kalashnikova

“…Calculations of the weighted average cost of conducting hypoglycemic therapy in DM1 can be used for further pharmacoeconomical calculations, including analysis of the medical and social cost of the disease.AIM: To conduct a pharmacoepidemiological analysis of the consumption of insulin preparations according to the ATX /DDD methodology, to study the modes of insulin administration and the ratio of the weighted average cost of insulin therapy components per 1 patient with DM1 per year in the outpatient practice of treatment with the introduction of insulin in the mode of multiple injections of insulin (MII) and during continuous subcutaneous insulin infusion (CSII).MATERIALS AND METHODS: A retrospective continuous cohort analytical pharmacoepidemiological study was conducted on the basis of the SRDM database (status as of 01/01/2020), in which 17,617 patients with T1DM aged 18 years and older were registered at the time of the study.RESULTS: 90% of patients received analogues of human insulin in the MII mode using syringe pens, 8.6% used the CSII mode. …”
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