Unveiling the role of iPLA2β in neurodegeneration: From molecular mechanisms to advanced therapies by Jiabin Liu, Jieqiong Tan, Beisha Tang, Jifeng Guo

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Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications by Jin Feng, Xiaohui Wang, Xiaochun Ye, Irma Ares, Bernardo Lopez-Torres, Marta Martínez, María-Rosa Martínez-Larrañaga, Xu Wang, Arturo Anadón, María-Aránzazu Martínez

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NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1 by Jianjian Zhang, Weibin Xie, Bin Ni, Zhuohang Li, Dengyuan Feng, Yao Zhang, Qianguang Han, Hai Zhou, Min Gu, Ruoyun Tan

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Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? by Ellis Nelissen, Melissa Schepers, Laura Ponsaerts, Sébastien Foulquier, Annelies Bronckaers, Tim Vanmierlo, Peter Sandner, Jos Prickaerts

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Properties of FDA-approved small molecule protein kinase inhibitors: A 2024 update by Robert Roskoski, Jr.

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Macrophage-related therapeutic strategies: Regulation of phenotypic switching and construction of drug delivery systems by Xi Wang, Yixuan Li, Xueyu Pu, Guiquan Liu, Honglin Qin, Weimin Wan, Yuying Wang, Yan Zhu, Jian Yang

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Autoantibodies against the glial glutamate transporter GLT1/EAAT2 in Type 1 diabetes mellitus—Clues to novel immunological and non-immunological therapies by Carla Perego, Eliana S. Di Cairano, Alessandra Galli, Stefania Moretti, Elena Bazzigaluppi, Victoria Frolich Centonze, Amalia Gastaldelli, Emma Assi, Paolo Fiorina, Massimo Federici, Ottavia Porzio, Federico Bertuzzi, Alberto M. Davalli, Franco Folli

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Quenching thirst with poison? Paradoxical effect of anticancer drugs by Kaiyuan Chai, Chuanlei Wang, Jianpeng Zhou, Wentao Mu, Menghan Gao, Zhongqi Fan, Guoyue Lv

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Metabolic disorders affecting the liver and heart: Therapeutic efficacy of miRNA-based therapies? by Lucia La Sala, Valentina Carlini, Caterina Conte, Maria Belen Macas-Granizo, Elham Afzalpour, Jimmy Martin-Delgado, Marco D’Anzeo, Roberto F.E. Pedretti, Angelo Naselli, Antonio E. Pontiroli, Riccardo Cappato

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Targeting TRPV1 and TRPA1: A feasible strategy for natural herbal medicines to combat postoperative ileus by Qi Liang, Jing-Wen Wang, Yu-Ru Bai, Ruo-Lan Li, Chun-Jie Wu, Wei Peng

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Low-dose Olaparib improves septic cardiac function by reducing ferroptosis via accelerated mitophagy flux by Ruixue Liu, Fengjuan Li, Shuai Hao, Dongyao Hou, Xue Zeng, He Huang, Gautam Sethi, Jun Guo, Chenyang Duan

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Biologics, theranostics, and personalized medicine in drug delivery systems by Matteo Puccetti, Marilena Pariano, Aurélie Schoubben, Stefano Giovagnoli, Maurizio Ricci

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Procyanidin B2 ameliorates endothelial dysfunction and impaired angiogenesis via the Nrf2/PPARγ/sFlt-1 axis in preeclampsia by Lei Liu, Rencheng Wang, Ran Xu, Yuening Chu, Weirong Gu

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The role of protein glycosylation in the occurrence and outcome of acute ischemic stroke by Jianzhuang Li, Yanmei Qiu, Chunlin Zhang, Hailing Wang, Rentang Bi, Yanhao Wei, Yanan Li, Bo Hu

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Cisplatin-based combination therapies: Their efficacy with a focus on ginsenosides co-administration by Keke Li, Jiwen Li, Zhongyu Li, Lei Men, Haibin Zuo, Xiaojie Gong

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Modulation of intestinal barrier function by glucocorticoids: Lessons from preclinical models by Mireia Tena-Garitaonaindia, María Arredondo-Amador, Cristina Mascaraque, Maitane Asensio, Jose J.G. Marin, Olga Martínez-Augustin, Fermín Sánchez de Medina

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Hydrogen sulfide and sulfaceutic or sulfanutraceutic agents: Classification, differences and relevance in preclinical and clinical studies by A. Martelli, R. d’Emmanuele di Villa Bianca, G. Cirino, R. Sorrentino, V. Calderone, M. Bucci

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Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth by Luisa Maresca, Enrica Crivaro, Francesca Migliorini, Giulia Anichini, Alessandro Giammona, Sara Pepe, Federica Poggialini, Chiara Vagaggini, Giuseppe Giannini, Serena Sestini, Lorenzo Borgognoni, Andrea Lapucci, Elena Dreassi, Maurizio Taddei, Fabrizio Manetti, Elena Petricci, Barbara Stecca

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Single-cell RNA-sequencing data reveals the genetic source of extracellular vesicles in esophageal squamous cell carcinoma by Bolun Zhou, Wei Guo, Lei Guo, Yong Li, Zhigang Zheng, Qilin Huai, Fengwei Tan, Yin Li, Qi Xue, Jianming Ying, Liang Zhao, Shugeng Gao, Jie He

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Penicopeptide A (PPA) from the deep-sea-derived fungus promotes osteoblast-mediated bone formation and alleviates ovariectomy-induced bone loss by activating the AKT/GSK-3β/β-caten... by Chun-Lan Xie, Yu-Ting Yue, Jing-Ping Xu, Na Li, Ting Lin, Guang-Rong Ji, Xian-Wen Yang, Ren Xu

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