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14721
Glucose-6-phosphate dehydrogenase activity measured by spectrophotometry and associated genetic variants from the Oromiya zone, Ethiopia
Published 2018-10-01“…Abstract Background The study aimed to gain first data on the prevalence of G6PD enzyme deficiency measured by spectrophotometry and associated genetic variants in Jimma and surroundings, Ethiopia. The area is a Plasmodium vivax endemic region, but 8-aminoquinolines such as primaquine are not recommended as G6PD testing is not available. …”
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14722
Characterization of lab-based swarms of Anopheles gambiae mosquitoes using 3D-video tracking
Published 2023-05-01“…Abstract Mosquito copulation is a crucial determinant of its capacity to transmit malaria-causing Plasmodium parasites as well as underpinning several highly-anticipated vector control methodologies such as gene drive and sterile insect technique. …”
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14723
Proteome-wide prediction and analysis of the Cryptosporidium parvum protein–protein interaction network through integrative methods
Published 2022-01-01“…Due to the lack of experimental PPIs of C. parvum, we used the PPI data of Plasmodium falciparum (P. falciparum), which owned the largest number of PPIs in Apicomplexa, to train an ML model to infer C. parvum PPIs. …”
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14724
Comparison of different methods for delayed post-mortem diagnosis of falciparum malaria
Published 2009-10-01“…</p> <p>Methods</p> <p>In order to evaluate different methods for the post-mortem diagnosis of <it>Plasmodium falciparum </it>malaria in non-immunes, a study was performed on the basis of forensic autopsies of corpses examined at variable intervals after death in five cases of fatal malaria (with an interval of four hours to five days), and in 20 cases of deaths unrelated to malaria. …”
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14725
TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimu...
Published 2011-08-01“…A recombinant His6-tagged FliC protein containing the C-terminal repeat regions of the VK210 variant of Plasmodium vivax circumsporozoite (CS) protein was constructed. …”
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14726
Quantitative analysis of immune response and erythropoiesis during rodent malarial infection.
Published 2010-09-01“…In this study, we use a statistical model-fitting approach to investigate the immune and erythropoietic responses in Plasmodium chabaudi infections of mice. Three mouse phenotypes (wildtype, T-cell-deficient nude mice, and nude mice reconstituted with T-cells taken from wildtype mice) were infected with one of two parasite clones (AS or AJ). …”
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14727
Malaria in Haiti: A descriptive study on spatial and temporal profile from 2009 to 2018
Published 2022-02-01“…More than 99% of malaria cases are caused by Plasmodium falciparum, the main vector being the mosquito Anopheles albimanus. …”
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14728
Analysis of codon usage bias of thioredoxin in apicomplexan protozoa
Published 2023-11-01“…Results The results showed that both codon base composition and relative synonymous codon usage (RSCU) analysis revealed that AT-ended codons were more frequently used in Cryptosporidium spp. and Plasmodium spp., while the Eimeria spp., Babesia spp., Hammondia hammondi, Neospora caninum, and Toxoplasma gondii tended to end in G/C. …”
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14729
High-Dose Primaquine Induces Proximal Tubular Degeneration and Ventricular Cardiomyopathy Linked to Host Cells Mitochondrial Dysregulation
Published 2023-02-01“…Primaquine (PQ) is the only antimalarial medication used to eradicate many species of <i>Plasmodium</i> gametocytes and prevent relapse in vivax and ovale malarias. …”
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14730
Maternal malaria and gravidity interact to modify infant susceptibility to malaria.
Published 2005-12-01“…In endemic areas, placental malaria due to Plasmodium falciparum is most frequent and severe in first-time mothers, and increases the risk of infant mortality in their offspring. …”
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14731
Efectividad de la quinina en el tratamiento de la malaria
Published 2023-03-01“…Metodos: Se realizó un estudio descriptivo de 59 pacientes adultos con paludismo por Plasmodium falciparum ingresados en el Departamento de Medicina del Instituto de Medicina Tropical Pedro Kouri, durante el período comprendido entre enero 2015- diciembre 2018. …”
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14732
COVID-19 and malaria co-infection: a systematic review of clinical outcomes in endemic areas
Published 2024-04-01“…These studies involved 2,810 patients, 618 of whom had COVID-19 and malaria co-infection. Plasmodium falciparum and vivax were identified as causative organisms in six studies. …”
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14733
Risk Association, Linkage Disequilibrium, and Haplotype Analyses of β-Like Globin Gene Polymorphisms with Malaria Risk in the Sabah Population of Malaysian Borneo
Published 2022-07-01“…In brief, DNA was extracted from 188 post-diagnostic blood samples infected with <i>Plasmodium</i> parasites and 170 healthy controls without a history of malaria. …”
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14734
Antimalarial activity of selected Ethiopian medicinal plants in mice
Published 2018-02-01“…Aims: To evaluate the in vivo antimalarial activities of hydroalcoholic extracts of the roots of Piper capense and Adhatoda schimperiana, against Plasmodium berghei in mice. Methods: Four-day suppressive and curative test animal models were used to explore the antimalarial activities of the plants. 200, 400, and 600 mg/kg of each plant extract was administered to check the activities versus vehicle administered mice. …”
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14735
Multi-step polynomial regression method to model and forecast malaria incidence.
Published 2009-01-01“…We considered three types of data to develop the regression methodology: a longer time series data of Slide Positivity Rates (SPR) of malaria; a smaller time series data (deaths due to Plasmodium vivax) of one year; and spatial data (zonal distribution of P. vivax deaths) for the city along with the climatic factors, population and previous incidence of the disease. …”
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14736
Progress of Science from Microscopy to Microarrays (Part 1): Diagnosis of Parasitic Diseases
Published 2009-01-01“…The best examples are vector-borne parasites, such as Plasmodium, Trypanosoma and Leishmania, in which genes expressed, during mammalian and insect host stages, have been elucidated. …”
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14737
Knowledge, Attitude, And Practices (KAP) Of Malaria Prevention Amongst Medical Students of Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria
Published 2022-11-01“…Results: Although 47.83% of respondents think malaria is a deadly disease and 98.81% affirmed it is preventable, almost all (≥98.42%) reported female anopheles’ mosquito and plasmodium as vector and causative agent, respectively. …”
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14738
Malaria, Urogenital Schistosomiasis, and Anaemia in Pregnant Ghanaian Women
Published 2023-01-01“…Moreover, women become susceptible to malaria during pregnancy. We investigated Plasmodium falciparum (P. falciparum) and Schistosoma haematobium (S. haematobium) infections and determined their association with anaemia during pregnancy. …”
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14739
Hemin treatment drives viral reactivation and plasma cell differentiation of EBV latently infected B cells.
Published 2023-08-01“…Epstein-Barr virus (EBV) and Plasmodium falciparum have a well described role in the development of endemic Burkitt lymphoma (BL), yet the mechanisms involved remain unknown. …”
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14740
Prevalence of haemosporidians in a Neotropical endemic bird area
Published 2016-06-01“…From the sampled birds, 32.1% were infected by at least 1 of 12 unique cyt b lineages of haemosporidian genera: Plasmodium, Leucocytozoon, Haemoproteus, and subgenus Parahaemoproteus. …”
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