Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from <i>Streptomyces</i> sp. H11809 by Fauze Mahmud, Ngit Shin Lai, Siew Eng How, Jualang Azlan Gansau, Khairul Mohd Fadzli Mustaffa, Chiuan Herng Leow, Hasnah Osman, Hasidah Mohd Sidek, Noor Embi, Ping-Chin Lee

“…H11809 exerted inhibitory activity against human GSK-3β (<i>Hs</i> GSK-3β) and <i>Plasmodium</i><i>falciparum</i> 3D7 (<i>Pf</i> 3D7) malaria parasites. …”
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The effect of holes in long-lasting insecticidal nets on malaria in Malawi: results from a case–control study by Anna A. Minta, Keren Z. Landman, Dyson A. Mwandama, Monica P. Shah, Jodi L. Vanden Eng, James F. Sutcliffe, Joseph Chisaka, Kim A. Lindblade, Don P. Mathanga, Laura C. Steinhardt

“…Cases were positive for Plasmodium falciparum asexual parasites by microscopy while controls were negative. …”
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Hepatotropic Peptides Grafted onto Maleimide-Decorated Nanoparticles: Preparation, Characterization and <i>In Vitro</i> Uptake by Human HepaRG Hepatoma Cells by Clarisse Brossard, Manuel Vlach, Lucas Jacquet, Elise Vène, Vincent Dorcet, Pascal Loyer, Sandrine Cammas-Marion, Nicolas Lepareur

“…We recently demonstrated the strong tropism of George Baker (GB) Virus A (GBVA10-9) and <i>Plasmodium circumsporozoite</i> protein (CPB) derived synthetic peptides towards hepatoma cells. …”
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In vitro antiplasmodial activity and toxicological profile of extracts, fractions and chemical constituents of leaves and stem bark from Dacryodes edulis (Burseraceae) by Kevine Johane Jumeta Dongmo, Mariscal Brice Tchatat Tali, Yannick Stéphane Fotsing Fongang, Pierre Leonel K. Tafokeu Taguimjeu, Donald Ulrich Kenou Kagho, Gabin Thierry Bitchagno, Bruno Ndjakou Lenta, Fabrice Fekam Boyom, Norbert Sewald, Silvère Augustin Ngouela

“…Methods Extracts, fractions, and some isolated compounds were subjected to antiplasmodial activity screening in vitro against chloroquine-sensitive 3D7 and multidrug resistant Dd2 strains of Plasmodium falciparum using a SyBr Green fluorescence-based assay. …”
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Spatiotemporal characterisation and risk factor analysis of malaria outbreak in Cabo Verde in 2017 by Adilson José DePina, Alex Jailson Barbosa Andrade, Abdoulaye Kane Dia, António Lima Moreira, Ullardina Domingos Furtado, Helga Baptista, Ousmane Faye, Ibrahima Seck, El Hadji Amadou Niang

“…These cases were primarily Plasmodium falciparum infections. Of these cases, 423 were indigenous infections recorded in Praia, while 23 were imported malaria cases from different African countries. …”
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Distinct parasite populations infect individuals identified through passive and active case detection in a region of declining malaria transmission in southern Zambia by Kelly M. Searle, Ben Katowa, Tamaki Kobayashi, Mwiche N. S. Siame, Sungano Mharakurwa, Giovanna Carpi, Douglas E. Norris, Jennifer C. Stevenson, Philip E. Thuma, William J. Moss, for the Southern Africa International Centers of Excellence for Malaria Research

“…A 24 single-nucleotide-polymorphism Plasmodium falciparum molecular barcode was used to characterize parasite populations from infected individuals identified through passive and active case detection in an area approaching malaria elimination in southern Zambia. …”
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Application of polymerization-based amplification in point-of-care diagnostics by Lathwal, Shefali

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Role of STEVOR and its interacting partners in parasite virulence by Omelianczyk, Radoslaw Igor

“…The genomes of Plasmodium spp. encode a number of different multigene families that are thought to play a critical role for survival. …”
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Application of economic analysis to evaluate various infectious diseases in Vietnam by Phuong, T

“…</p> <p>Increasing resistance of <em>Plasmodium falciparum</em> malaria to <em>artemisinin</em> is posing a major threat to the global effort to eliminate malaria. …”

Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

“…<strong>Background</strong> Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. …”

The public health impact and cost-effectiveness of the R21/Matrix-M malaria vaccine: a mathematical modelling study by Schmit, N, Topazian, HM, Natama, HM, Bellamy, D, Traoré, O, Somé, MA, Rouamba, T, Tahita, MC, Bonko, MDA, Sourabié, A, Sorgho, H, Stockdale, L, Provstgaard-Morys, S, Aboagye, J, Woods, D, Rapi, K, Datoo, MS, Ramos Lopez, F, Charles, GD, McCain, K, Ouedraogo, J-B, Hamaluba, M, Olotu, A, Dicko, A, Tinto, H, Hill, AVS, Ewer, KJ, Ghani, AC, Winskill, P

“…<p><strong>Background</strong> The R21/Matrix-M vaccine has demonstrated high efficacy against Plasmodium falciparum clinical malaria in children in sub-Saharan Africa. …”

Sickle cell anaemia and severe P. falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT) by Uyoga, S, Olupot-Olupot, P, Connon, R, Kiguli, S, Opoka, RO, Alaroker, F, Muhindo, R, Macharia, A, Dondorp, A, Gibb, DM, Walker, AS, George, EC, Maitland, K, Williams, TN

“…We aimed to explore the relationship between SCA and Plasmodium falciparum malaria in further detail by investigating the burden and severity of malaria infections among children recruited with severe anaemia to the TRACT trial of blood transfusion in Africa.…”

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis by Abdulla, S, Ashley, E, Bassat, Q, Bethell, D, Bjorkman, A, Borrmann, S, D'Alessandro, U, Dahal, P, Day, N, Diakite, M, Djimde, A, Dondorp, A, Duong, S, Edstein, MD, Fairhurst, R, Faiz, M, Falade, C, Flegg, J, Fogg, C, Gonzalez, R, Greenwood, B, Guerin, P, Guthmann, J, Hamed, K, Hien, T, Htut, Y, Juma, E, Lim, P, Martensson, A, Mayxay, M, Mokuolu, O, Moreira, C, Newton, P, Noedl, H, Nosten, F, Ogutu, B, Onyamboko, M, Owusu-Agyei, S, Phyo, A, Premji, Z, Price, R, Pukrittayakamee, S, Ramharter, M, Sagara, I, Se, Y, Suon, S, Stepniewska, K, Ward, SA, White, N, Winstanley, P, Grp, W

“…<strong>Background:</strong> Artemisinin resistance in Plasmodium falciparum manifests as slow parasite clearance but this measure is also influenced by host immunity, initial parasite biomass and partner drug efficacy. …”

Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malaria by Mukaka, M, Onyamboko, MA, Olupot-Olupot, P, Peerawaranun, P, Suwannasin, K, Pagornrat, W, Kouhathong, J, Madmanee, W, Were, W, Namayanja, C, Onyas, P, Titin, H, Baseke, J, Muhindo, R, Kayembe, DK, Ndjowo, PO, Basara, BB, Bongo, GS, Okalebo, CB, Abongo, G, Uyoga, S, Williams, TN, Taya, C, Dhorda, M, Dondorp, AM, Waithira, N, Imwong, M, Maitland, K, Fanello, C, Day, NPJ, Tarning, J, White, NJ, Taylor, WRJ

“…<p><strong>Background:</strong> There are no pharmacokinetic data of single low dose primaquine (SLDPQ) as transmission blocking in African children with acute Plasmodium falciparum and glucose-6-phosphate dehydrogenase deficiency (G6PDd).…”

Developing a new anti-sporozoite malaria vaccine by Datoo, MS

“…</p> <p>R21 is produced by using recombinant HBsAg particles expressing the central repeat and the C-terminus of the <i>Plasmodium falciparum</i> circumsporozoite protein. …”

Evaluation of the protective efficacy of a spatial repellent to reduce malaria incidence in children in Mali compared to placebo: study protocol for a cluster-randomized double-bli... by Suzanne Van Hulle, Issaka Sagara, Momar Mbodji, Ghislain Ismael Nana, Mamadou Coulibaly, Alassane Dicko, Mamady Kone, Ismaila Thera, Daman Sylla, Mamadou Diango Traore, Fang Liu, John P. Grieco, Nicole L. Achee

“…Over the past decade, the Region of Sikasso, Health districts of Kadiolo, Yorosso, and Kolondieba have remained among the most afflicted, characterized by an annual parasite incidence of more than 116 cases per 1000 population [1] and a Plasmodium falciparum prevalence rate of 29.7% [2]. …”
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Symposium - De la recherche à la production industrielle des produits de santé (Présentations d'expériences réussies) Expérience n°2 : PHYTOMED de la Côte d’Ivoire by Gisèle KOUAKOU SIRANSY

“…De ces extraits ceux présentant les meilleures inhibitions de croissance du Plasmodium selon les critères de Wilcox, ont été retenues pour la mise au point de phytomédicaments de catégorie 2 OMS. …”
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Anopheles rufipes implicated in malaria transmission both indoors and outdoors alongside Anopheles funestus and Anopheles arabiensis in rural south-east Zambia by Kochelani Saili, Christiaan de Jager, Onyango P. Sangoro, Theresia E. Nkya, Freddie Masaninga, Mwansa Mwenya, Andy Sinyolo, Busiku Hamainza, Emmanuel Chanda, Ulrike Fillinger, Clifford M. Mutero

“…Specimens belonging to the Anopheles gambiae complex and Anopheles funestus group were further identified using molecular techniques. Plasmodium falciparum sporozoite infection was determined using sandwich enzyme-linked immunosorbent assays. …”
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Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR [version 2; peer review: 2 approved] by Stella Mwakio, Anna C. Seale, Wilson Gumbi, Christina W. Obiero, Mami Taniuchi, James A. Berkley, Hope Mwangudzah, Eric Houpt, Jie Liu

“…Cumulative odds ratios across controls: cases (survived): cases (died) were E. coli/Shigella spp. 2.6 (95%CI 1.6-4.4); E. faecalis 4.0 (95%CI 1.1-15); S. agalactiae 4.5 (95%CI 1.6-13); Ureaplasma spp. 2.9 (95%CI 1.3-6.4); Enterovirus 9.1 (95%CI 2.3-37); and Plasmodium spp. 2.9 (95%CI 1.4-6.2). Excluding K. oxytoca and P. aeruginosa as likely contaminants, aetiology was attributed in 9.4% (95%CI 5.1-13) cases using TAC. …”
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Relationship between changing malaria burden and low birth weight in sub-Saharan Africa: A difference-in-differences study via a pair-of-pairs approach by Siyu Heng, Wendy P O'Meara, Ryan A Simmons, Dylan S Small

“…Results: A malaria prevalence decline from a high rate (Plasmodium falciparum parasite rate in children aged 2-up-to-10 (i.e. …”
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