Review Article: blood-brain barrier in falciparum malaria. by Gitau, E, Newton, C

“…Plasmodium falciparum malaria is the most important parasitic disease infecting the central nervous system of humans worldwide. …”

Persistent low avian malaria in a tropical species despite high community prevalence by Justin R. Eastwood, Lee Peacock, Michelle L. Hall, Michael Roast, Stephen A. Murphy, Anders Gonçalves da Silva, Anne Peters

“…Keywords: Avian malaria, Wildlife diseases, Purple-crowned fairy-wrens, Haemoproteus, Plasmodium…”
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The 'non-falciparum' malarias: the roles of epidemiology, parasite biology, clinical syndromes, complications and diagnostic rigour in guiding therapeutic strategies. by Maguire, J, Baird, J

“…Plasmodium vivax, P. ovale, P. malariae and P. falciparum routinely infect humans. …”

Prevention and treatment of vivax malaria. by Baird, J, Schwartz, E, Hoffman, S

“…Plasmodium vivax is a significant public health threat throughout most of the tropics and to travelers to these regions. …”

Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies. by Carlson, J, Helmby, H, Hill, A, Brewster, D, Greenwood, B, Wahlgren, M

“…Plasmodium falciparum isolates from 24 Gambian children with cerebral malaria and 57 children with mild forms of the disease were assessed for their ability to form erythrocyte rosettes. …”

Management of severe falciparum malaria. by Njuguna, P, Newton, C

“…Plasmodium falciparum is the most common cause of severe and life-threatening malaria. …”

Vivax malaria: neglected and not benign. by Price, R, Tjitra, E, Guerra, C, Yeung, S, White, N, Anstey, N

“…Plasmodium vivax threatens almost 40% of the world's population, resulting in 132-391 million clinical infections each year. …”

Vivax malaria: neglected and not benign. by Price, R, Tjitra, E, Guerra, C, Yeung, S, White, N, Anstey, N

“…Plasmodium vivax threatens almost 40% of the world's population, resulting in 132-391 million clinical infections each year. …”

Blood-stage malaria vaccines - recent progress and future challenges. by Goodman, A, Draper, S

“…Plasmodium falciparum malaria is a major global health problem, responsible for up to 1 million deaths each year. …”

Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria. by Lee, E, Palmer, DR, Flanagan, K, Reece, W, Odhiambo, K, Marsh, K, Pinder, M, Gravenor, M, Keitel, W, Kester, K, Diggs, C, Kaslow, D, Apostolopoulos, V, Ballou, W, Hill, A, Krzych, U, Plebanski, M

“…Plasmodium falciparum malaria is a major cause of death in the tropics. …”

Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions by Cutts, E, Laasch, N, Reiter, D, Trenker, R, Slater, L, Stansfeld, P, Vakonakis, I

“…Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) and Knob-associated Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. …”

A review of the current status of G6PD deficiency testing to guide radical cure treatment for vivax malaria by Sadhewa, A, Cassidy-Seyoum, S, Acharya, S, Devine, A, Price, RN, Mwaura, M, Thriemer, K, Ley, B

“…Plasmodium vivax malaria continues to cause a significant burden of disease in the Asia-Pacific, the Horn of Africa, and the Americas. …”

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens. by Tan, J, Pieper, K, Piccoli, L, Abdi, A, Foglierini, M, Geiger, R, Tully, C, Jarrossay, D, Ndungu, F, Wambua, J, Bejon, P, Fregni, C, Fernandez-Rodriguez, B, Barbieri, S, Bianchi, S, Marsh, K, Thathy, V, Corti, D, Sallusto, F, Bull, P, Lanzavecchia, A

“…Plasmodium falciparumantigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies. …”

Variable var transition rates underlie antigenic variation in malaria. by Horrocks, P, Pinches, R, Christodoulou, Z, Kyes, SA, Newbold, C

“…Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is expressed on the surface of infected erythrocytes where it plays a central role in both infected erythrocytes cytoadhesion and immune evasion. …”

Dynamic alteration in splenic function during acute falciparum malaria. by Looareesuwan, S, Ho, M, Wattanagoon, Y, White, N, Warrell, D, Bunnag, D, Harinasuta, T, Wyler, D

“…Plasmodium-infected erythrocytes lose their normal deformability and become susceptible to splenic filtration. …”

Atypical brain response to novelty in rural African children with a history of severe falciparum malaria. by Kihara, M, de Haan, M, Garrashi, H, Neville, BG, Newton, C

“…Plasmodium falciparum is the most common parasitic infection of the central nervous system causing neuro-cognitive deficits in 5-26% of paediatric cases. …”

Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies by King, LDW, Pulido, D, Barrett, JR, Davies, H, Quinkert, D, Lias, AM, Silk, SE, Pattinson, DJ, Diouf, A, Williams, BG, McHugh, K, Rodrigues, A, Rigby, CA, Strazza, V, Suurbaar, J, Rees-Spear, C, Dabbs, RA, Ishizuka, AS, Zhou, Y, Gupta, G, Jin, J, Li, Y, Carnrot, C, Minassian, AM, Campeotto, I, Fleishman, SJ, Noe, AR, MacGill, RS, King, CR, Birkett, AJ, Soisson, LA, Long, CA, Miura, K, Ashfield, R, Skinner, K, Howarth, MR, Biswas, S, Draper, SJ

“…Plasmodium falciparum reticulocyte-binding protein homolog 5 (RH5) is a leading blood-stage malaria vaccine antigen target, currently in a phase 2b clinical trial as a full-length soluble protein/adjuvant vaccine candidate called RH5.1/Matrix-M. …”

Development of an Immunosensor for PfHRP 2 as a Biomarker for Malaria Detection by Aver Hemben, Jon Ashley, Ibtisam E. Tothill

“…Plasmodium falciparum histidine-rich protein 2 (PfHRP 2) was selected in this work as the biomarker for the detection and diagnosis of malaria. …”
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Recent advances in recombinant protein-based malaria vaccines. by Draper, S, Angov, E, Horii, T, Miller, L, Srinivasan, P, Theisen, M, Biswas, S

“…Plasmodium parasites are the causative agent of human malaria, and the development of a highly effective vaccine against infection, disease and transmission remains a key priority. …”

Identification de la co-infection salmonellose-paludisme chez les malades consultés dans les structures sanitaires de N’zérékoré, Guinée by M SANGARE, et. al

“…Méthodologie : La Polymérase Chaine Réaction (PCR) pour la recherche des Salmonella, le Test de Diagnostic Rapide (TDR), le frottis mince, confirmés par la Goutte Epaisse (GE) pour l'identification des plasmodiums ont été réalisées. Résultats : Sur un total de 900 patients enregistrés dans les formations sanitaires de la région de N’zérékoré entre le 1er Mars et le 30 Mai 2022, 442 cas de syndromes fébriles ont été identifiés, dont 183 cas de paludisme seul, soit 20,33%; 126 cas de salmonellose seule, 14%; 133 cas de co-infection Salmonellose-Paludisme soit 14,78% et 458 cas de syndrome de fièvre non déterminés soit 50,89%. …”
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