Maintenance of the Plasmodium berghei life cycle. by Sinden, R, Butcher, G, Beetsma, A

Neddylation is essential for malaria transmission in Plasmodium berghei by Bandita Nayak, Plabita Paul, Satish Mishra

“…Here, for the first time, we showed that neddylation plays an essential role in malaria transmission in Plasmodium berghei. We found that disruption of Nedd8 did not affect blood-stage propagation, gametocyte development, gamete formation, or zygote formation while abolishing the formation of ookinetes and further transmission of the parasites in mosquitoes. …”
Get full text

Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei. by Noah Machuki Onchieku, Reagan Mogire, Loise Ndung'u, Peter Mwitari, Francis Kimani, Damaris Matoke-Muhia, Daniel Kiboi, Gabriel Magoma

“…Using reverse genetics approach, we embarked on separately generating knockout (KO) parasite lines lacking Plasmepsin 4 (PM4), PM7, PM8, or DNA damage-inducible protein 1 (Ddi1) in the rodent malaria parasite Plasmodium berghei ANKA. We then tested the suppressive profiles of the LP/Ritonavir (LP/RT) and SQ/RT as well as antimalarials; Amodiaquine (AQ) and Piperaquine (PQ) against the KO parasites in the standard 4-day suppressive test. …”
Get full text

Intravital observation of Plasmodium berghei sporozoite infection of the liver. by Ute Frevert, Sabine Engelmann, Sergine Zougbédé, Jörg Stange, Bruce Ng, Kai Matuschewski, Leonard Liebes, Herman Yee

“…To obtain direct information on the dynamics of sporozoite infection of the liver, we infected live mice with red or green fluorescent Plasmodium berghei sporozoites and monitored their behavior using intravital microscopy. …”
Get full text

Pharmacologically active chemical mediators in plasmodium berghei malaria by Renato S. B. Cordeiro, Marco A. Martins, Fernando Q. Cunha, Vivian B. Weg, Jamil A. Filho, Carlos A. Flores, Patricia M. R. e Silva, Maria G. M. O. Henriques

Get full text

Effects of levamisole on experimental infections by Plasmodium berghei in mice by Enrique Melendez C., Antoniana U. Krettli

Subjects: Get full text

Effects of levamisole on experimental infections by Plasmodium berghei in mice by Enrique Melendez C., Antoniana U. Krettli

Subjects: Get full text

The role of metacaspase 1 in Plasmodium berghei development and apoptosis. by Le Chat, L, Sinden, R, Dessens, J

“…We have generated Plasmodium berghei parasites in which the PbMC1coding sequence is removed and replaced with a green fluorescent reporter gene to investigate the expression of PbMC1, its contribution to parasite development, and its involvement in previously reported apoptosis-like cell death of P. berghei ookinetes. …”

Transcriptome analysis of Anopheles stephensi-Plasmodium berghei interactions. by Xu, X, Dong, Y, Abraham, E, Kocan, A, Srinivasan, P, Ghosh, A, Sinden, R, Ribeiro, J, Jacobs-Lorena, M, Kafatos, F, Dimopoulos, G

“…Simultaneous microarray-based transcription analysis of 4987 Anopheles stephensi midgut and Plasmodium berghei infection stage specific cDNAs was done at seven successive time points: 6, 20 and 40h, and 4, 8, 14 and 20 days after ingestion of malaria infected blood. …”

Penglibatan protein fosfotirosin dalam infeksi plasmodium berghei by Hasidah Mohd Sidek, Chee , Suan Kim, Rohani Abd. Kadir

“…This study was carried out to assess the relationship between Plasmodium berghei infection and the eryth­rocyte level of phosphotyrosine-containing proteins in mice. …”

Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development by Silvia Sanz, Silvia Sanz, Silvia Sanz, Eleonora Aquilini, Rebecca E. Tweedell, Rebecca E. Tweedell, Garima Verma, Garima Verma, Timothy Hamerly, Timothy Hamerly, Bernadette Hritzo, Abhai Tripathi, Marta Machado, Thomas S. Churcher, João A. Rodrigues, Luis Izquierdo, Rhoel R. Dinglasan, Rhoel R. Dinglasan

Subjects: Get full text

STUDI IMUNOSTIMULAN EKSTRAK TOMAT PADA INFEKSI PLASMODIUM BERGHEI by Retno Sri Iswari

Subjects: “…Ekstrak tomat, Plasmodium berghei, kadar FN-?, kadar IL-4, kadar IL-12…”
Get full text

Influence of midgut microbiota in Anopheles stephensi on Plasmodium berghei infections by Devaiah Monnanda Kalappa, Pradeep Annamalai Subramani, Sowmya Kanchanahalli Basavanna, Susanta Kumar Ghosh, Varadharajan Sundaramurthy, Sreehari Uragayala, Satyanarayan Tiwari, Anupkumar R. Anvikar, Neena Valecha

Subjects: Get full text

Dexamethasone increased the survival rate in Plasmodium berghei-infected mice by Danilo Reymão Moreira, Ana Carolina Musa Gonçalves Uberti, Antonio Rafael Quadros Gomes, Michelli Erica Souza Ferreira, Aline da Silva Barbosa, Everton Luiz Pompeu Varela, Maria Fani Dolabela, Sandro Percário

“…Abstract The present study aimed to evaluate the effects of dexamethasone on the redox status, parasitemia evolution, and survival rate of Plasmodium berghei-infected mice. Two-hundred and twenty-five mice were infected with Plasmodium berghei and subjected to stimulation or inhibition of NO synthesis. …”
Get full text

The Impact of Plasmodium Berghei Exposure In-utero on Neurobehavioral Profile in Mice by Akhabue Keneth Okojie, Khalid Rauf, Eghosa Iyare

Subjects: “…Plasmodium berghei…”
Get full text

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent. by Robert E Sinden, Emma J Dawes, Yasmene Alavi, Joanna Waldock, Olivia Finney, Jacqui Mendoza, Geoff A Butcher, Laura Andrews, Adrian V Hill, Sarah C Gilbert, María-Gloria Basáñez

“…Here we establish infections with defined numbers of the rodent malaria parasite Plasmodium berghei to examine how parasite density at each stage of development (gametocytes; ookinetes; oocysts and sporozoites) influences development to the ensuing stage in Anopheles stephensi, and thus the delivery of infectious sporozoites to the vertebrate host. …”
Get full text

The identification of FERM domain protein in serum infected with Plasmodium berghei by Vathsala P.G., Krishna Murthy P.

Subjects: Get full text

Improvement of the observational method for <it>Plasmodium berghei </it>oocysts in the midgut of mosquitoes by Kawazu Shin-ichiro, Inoue Noboru, Fukumoto Shinya, Usui Miho

“…<p>Abstract</p> <p>Background</p> <p>There is a need for improving the method for counting oocysts of <it>Plasmodium berghei </it>in the midgut of <it>Anopheles </it>mosquitoes. …”
Get full text

Cytotoxicity and Anti-Plasmodium berghei Activity of Emodin Loaded Nanoemulsion by Fatemeh Bayat, Afsaneh Motevalli Haghi, Mehdi Nateghpour, Bahman Rahimi-Esboei, Abbas Rahimi Foroushani, Amir Amani, Leila Farivar, Zahra Sayyad Talaee, Aref Faryabi

Subjects: Get full text

Expression and Localization Profiles of Rhoptry Proteins in Plasmodium berghei Sporozoites by Naohito Tokunaga, Mamoru Nozaki, Mayumi Tachibana, Minami Baba, Kazuhiro Matsuoka, Takafumi Tsuboi, Motomi Torii, Tomoko Ishino

“…With the aim of comprehensively describing the mechanisms of sporozoite invasion, the expression and localization profiles of rhoptry proteins were investigated in Plasmodium berghei sporozoites. Of 12 genes representing merozoite rhoptry molecules, nine are transcribed in oocyst-derived sporozoites at a similar or higher level compared to those in blood-stage schizonts. …”
Get full text