Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature. by Kerstin Baer, Christian Klotz, Stefan H I Kappe, Thomas Schnieder, Ute Frevert

Get full text

Global genomics analysis of the rodent malaria parasites Plasmodium Berghei, Plasmodium Chabaudi and Plasmodium Yoelii with emphasis on the identification of novel virulence factors in Plasmodium Yoelii by Liew, Kingsley Jiin Liang

Get full text

The dCas9-based genome editing in Plasmodium yoelii by Chao Zhang, Shijie Yang, Elvis Quansah, Ziyu Zhang, Weiran Da, Bingjie Wang

“…Here, we demonstrated the use of dCas9-single-stranded annealing protein, as the cleavage-free gene editor in Plasmodium yoelii, by targeted deletion and gene tagging, even using shorter homologous DNA templates. …”
Get full text

Plasmodium yoelii: blood oxygen and brain function in the infected mouse. by Krishna, S, Shoubridge, E, White, N, Weatherall, D, Radda, G

“…The carriage of oxygen by the blood and the in vivo response of the brain were investigated in mice infected with a lethal strain of Plasmodium yoelii. All mice with parasitaemia exceeding 70% were severely anaemic (Hb 3.5 +/- 1.8 g/dl; mean +/- 1 SD), acidotic (blood pH 7.04 +/- 0.06) and hypoglycaemic (blood glucose 0.6 +/- 0.76 mumol/ml). …”

Contributions of IFN-γ and granulysin to the clearance of Plasmodium yoelii blood stage. by Natália Satchiko Hojo-Souza, Patrick Orestes de Azevedo, Júlia Teixeira de Castro, Andréa Teixeira-Carvalho, Judy Lieberman, Caroline Junqueira, Ricardo Tostes Gazzinelli

Get full text

Validation of Plasmodium vivax centromere and promoter activities using Plasmodium yoelii. by Kittisak Thawnashom, Miho Kaneko, Phonepadith Xangsayarath, Nattawat Chaiyawong, Kazuhide Yahata, Masahito Asada, John H Adams, Osamu Kaneko

“…Centromere activity was evaluated using a rodent malaria parasite Plasmodium yoelii. A plasmid carrying PvCEN was stably maintained in asexual-stage parasites in the absence of drug pressure, and approximately 45% of the parasites retained the plasmid four weeks later. …”
Get full text

Apoptosis of non-parasitised red blood cells in Plasmodium yoelii malaria by Paulo Renato Rivas Totino, Raquel Alves Pinna, Ana Cecilia Amado Xavier De-Oliveira, Dalma Maria Banic, Claudio Tadeu Daniel-Ribeiro, Maria de Fatima Ferreira-da-Cruz

“…Recently, while studying erythrocytic apoptosis during Plasmodium yoelii infection, we observed an increase in the levels of non-parasitised red blood cell (nRBC) apoptosis, which could be related to malarial anaemia. …”
Get full text

Transcriptional analysis of the pre-erythrocytic stages of the rodent malaria parasite, Plasmodium yoelii. by Calvin T Williams, Abdu F Azad

“…To gain insights into the molecular events that occur during the pre-erythrocytic stages of Plasmodium, comparative transcriptional analysis was performed on radiation attenuated sporozoites (RAS), wild type sporozoites (wtSPZ) and liver stage parasites collected either 24 hours (24hrLS) or 48 hours (48hrLS) after mice were infected with Plasmodium yoelii. Our results revealed 1100 Plasmodium genes that were differentially expressed in one or more constituents of the pre-erythrocytic stages relative to the mixed blood stages. …”
Get full text

Standard Selection Treatments with Sulfadiazine Limit Plasmodium yoelii Host-to-Vector Transmission by Kelly T. Rios, Taylor M. Dickson, Scott E. Lindner

Subjects: Get full text

A <it>Plasmodium yoelii </it>soluble factor inhibits the phenotypic maturation of dendritic cells by Ocaña-Morgner Carlos, Wong Kurt A, Orengo Jamie M, Rodriguez Ana

“…</p> <p>Methods</p> <p>Mice infected with <it>Plasmodium yoelii </it>and isolated <it>P. yoelii</it>-infected erythrocytes were used to study their effect on the maturation of mouse dendritic cells.…”
Get full text

Within-host competition does not select for virulence in malaria parasites; studies with Plasmodium yoelii. by Hussein M Abkallo, Julie-Anne Tangena, Jianxia Tang, Nobuyuki Kobayashi, Megumi Inoue, Augustin Zoungrana, Nick Colegrave, Richard Culleton

“…Here we use the rodent malaria parasite Plasmodium yoelii to assess the consequences of mixed strain infections on disease severity and parasite fitness. …”
Get full text

Differential gene expression in Anopheles stephensi following infection with drug-resistant Plasmodium yoelii by Jingru Zhang, Jiacheng Huang, Feng Zhu, Jian Zhang

Get full text

Plasmodium yoelii Erythrocyte Binding Like Protein Interacts With Basigin, an Erythrocyte Surface Protein by Takaaki Yuguchi, Bernard N. Kanoi, Hikaru Nagaoka, Toyokazu Miura, Daisuke Ito, Hiroyuki Takeda, Takafumi Tsuboi, Eizo Takashima, Hitoshi Otsuki

Subjects: “…Plasmodium yoelii…”
Get full text

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections. by Lorena Martin-Jaular, Ernesto S Nakayasu, Mireia Ferrer, Igor C Almeida, Hernando A Del Portillo

“…Here, we describe the isolation and characterization of exosomes from peripheral blood of BALB/c mice infected with the reticulocyte-prone non-lethal Plasmodium yoelii 17X strain. Importantly, proteomic analysis revealed the presence of parasite proteins in these vesicles. …”
Get full text

The role of serine-type serine repeat antigen in Plasmodium yoelii blood stage development. by Ximei Huang, Kingsley Liew, Onguma Natalang, Anthony Siau, Neng Zhang, Peter Rainer Preiser

“…The rodent malaria parasite Plasmodium yoelii has been extensively used to investigate the mechanisms of parasite virulence in vivo and a number of important proteins have been identified as being key contributors to pathology. …”
Get full text

Effect of Etanercept on <i>Plasmodium yoelii</i> MDR-Induced Liver Lipid Infiltration by Bhavana Singh Chauhan, Sarika Gunjan, Sunil Kumar Singh, Swaroop Kumar Pandey, Renu Tripathi

“…In the present study, we have correlated the significant increase in serum TNF-α and liver triglyceride during <i>Plasmodium yoelii</i> MDR infection in mice. In order to explore the role of TNF-α in inducing lipid accumulation in the liver during malaria infection, we have used a competitive TNF-α inhibitor Etanercept, for the treatment of <i>Plasmodium yoelii</i> MDR (<i>Py</i> MDR) infected mice and found that Etanercept displayed up to a three-fold inhibition of the liver triglyceride level in <i>Py</i> MDR infected mice. …”
Get full text

Plasmodium yoelii-infected A. stephensi inefficiently transmit malaria compared to intravenous route. by Solomon Conteh, Rana Chattopadhyay, Charles Anderson, Stephen L Hoffman

Get full text

Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion by Mana Miyakoda, Mana Miyakoda, Ganchimeg Bayarsaikhan, Daisuke Kimura, Daisuke Kimura, Masoud Akbari, Heiichiro Udono, Katsuyuki Yui, Katsuyuki Yui

“…Mice were infected with Plasmodium yoelii and administered metformin. Levels of parasitemia were reduced in treated mice compared with those in untreated mice, starting at ~2 weeks post-infection. …”
Get full text

In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice. by Mynthia Cabrera, Lecia L Pewe, John T Harty, Ute Frevert

Get full text

Identification of a new export signal in Plasmodium yoelii : identification of a new exportome by Siau, Anthony, Huang, Ximei, Yam, Xue Yan, Bob, Ndeye Sakha, Sun, Hequan, Rajapakse, Jagath C., Renia, Laurent, Preiser, Peter R.

Get full text
Get full text