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2101
A study on the immunological vitality of an inflammatory biomarker explored with rs5743708 polymorphism in TLR2 gene among Saudi women confirmed with polycystic ovarian syndrome
Published 2023-07-01“…Introduction: Polycystic ovary syndrome (PCOS) is an ovarian health condition as well as a long-term endocrine dysfunction that affects reproductive-aged women. …”
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2102
Effects of Selected Metal Nanoparticles (Ag, ZnO, TiO<sub>2</sub>) on the Structure and Function of Reproductive Organs
Published 2022-08-01“…Metal nanoparticles most likely induce polycystic ovary syndrome and follicular atresia, inflammation, apoptosis, and necrosis also occurred.…”
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2103
تقييم الخطورة القلبية الوعائية بالاعتماد على الصيغة الشحمية لدى مجموعة من مريضات متلازمة المبيض متعدد الكيسات...
Published 2023-12-01“… مقدمة: تعد متلازمة المبيض متعدد الكيسات Polycystic ovary syndrome (PCOs) إحدى أكثر الاضطرابات الصَّماوية شيوعاً ومن المعروف أنَّ اضطراب الشحوم يشكّل عامل مؤهب لتطوُّر الداء السُّكري من النمط الثاني وزيادة خطورة الإصابة القلبية الوعائية هدف البحث: تقييم مستويات الشحوم لدى مريضات المتلازمة ومن ثم تحديد المجموعات ذات الخطورة العالية ومن ثم تقييم الخطورة القلبية الوعائية لدى مريضات متلازمة المبيض متعدد الكيسات من خلال معايرة الصيغة الشحمية بالاعتماد على مشعر التصلب العصيدي Atherogenic index of plasma (AIP) المواد والطرائق: شملت الدراسة الوصفية 59 مريضة من المريضات المراجعات لمشفى تشرين الجامعي في اللاذقية ، بالمقارنة مع مجموعة شواهد مكونة من 20 من الإناث الأصحاء، تراوحت أعمار المريضات بين 18و 38 عاماً، تم إجراء تحاليل مخبرية للمريضات تضم معايرة عناصر الصيغة اللبيدية وتحديد مشعر الخطورة التصلب العصيدي(AIP) الذي يُحسب من اللوغاريتم العشري لنسبة ثلاثيات الغليسريد إلى الليبوبروتين الشحمي عالي الكثافة. …”
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2104
The complex metabolic interactions of liver tissue and hepatic exosome in PCOS mice at young and middle age
Published 2022-09-01“…Polycystic ovary syndrome (PCOS) is a common age-related endocrinopathy that promotes the metabolic disorder of the liver. …”
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2105
Alpha lipoic acid administration improved both peripheral sensitivity to insulin and liver clearance of insulin reducing potential risk of diabetes and nonalcoholic fatty liver dis...
Published 2024-12-01“…AbstractObjective To evaluate the effects of alpha lipoic acid (ALA) on hormonal and metabolic parameters in a group of overweight/obese Polycystic Ovary Syndrome (PCOS) patients.Methods This was a retrospective study in which thirty-two overweight/obese patients with PCOS (n = 32) not requiring hormonal treatment were selected from the database of the ambulatory clinic of the Gynecological Endocrinology Center at the University of Modena and Reggio Emilia, Italy. …”
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2106
Metformin Treatment Regulates the Expression of Molecules Involved in Adiponectin and Insulin Signaling Pathways in Endometria from Women with Obesity-Associated Insulin Resistance...
Published 2022-04-01“…Polycystic ovary syndrome (PCOS) is an endocrine/metabolic disorder associated with insulin resistance (IR) and obesity. …”
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2107
Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients
Published 2023-01-01“…Background. Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age, whose clinical characteristics are hyperandrogenism (HA), ovulatory dysfunction, and polycystic ovary, often accompanied by insulin resistance (IR) and metabolic abnormalities. …”
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2108
Performance Analysis of a Novel Hybrid Segmentation Method for Polycystic Ovarian Syndrome Monitoring
Published 2023-02-01“…Experts have used ultrasound imaging to manually determine follicle count and perform measurements, especially in cases of polycystic ovary syndrome (PCOS). However, due to the laborious and error-prone process of manual diagnosis, researchers have explored and developed medical image processing techniques to help with diagnosing and monitoring PCOS. …”
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2109
The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps
Published 2016-05-01“…Thirty seven women older than 40 years of age (study group), and 113 women younger than 40 years (control group) were compared in terms of various clinical and laboratory parameters including age, body mass index (BMI), gravidity, parity, abortion, basal hormone levels, tumor markers, complete blood count values, smoking status, presence of polycystic ovary syndrome (PCOS), infertility status, co-morbidities, and number and size of endometrial polyps. …”
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2110
Assessment of Nutritional Status and Its Influence on Ovarian Reserve: A Systematic Review
Published 2023-05-01“…In seven publications (31.8%), the increased body mass index (BMI) led to a decrease in ovarian reserve, two of them (0.9%) in patients with polycystic ovary syndrome, showing a decrease only if BMI > 25. …”
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2111
Metabolic cardiovascular disease risk factors in women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study.
Published 2004“…The metabolic cardiovascular disease (CVD) risk factors of women with self-reported oligomenorrhea and/or hirsutism, which are symptoms of polycystic ovary syndrome (PCOS), were investigated in a general population-based Northern Finland Birth Cohort 1966 Study to determine whether women with PCOS symptoms at 31 yr would be distinguishable from asymptomatic controls in terms of CVD risk factors. …”
Journal article -
2112
Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.
Published 2004“…Women with polycystic ovary syndrome (PCOS) have high circulating androgens, thought to originate from ovaries and adrenals, and frequently suffer from the metabolic syndrome including obesity. …”
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2113
Prevalence of polycystic ovaries in women with self-reported symptoms of oligomenorrhoea and/or hirsutism: Northern Finland Birth Cohort 1966 Study.
Published 2004“…METHODS: The ultrasonographic ovarian morphology and the hormonal and metabolic profile of female cases with self-reported symptoms typical of polycystic ovary syndrome (PCOS) (n = 196) and asymptomatic controls (n = 67) at the age of 31 years were examined in a general population-based Northern Finland Birth Cohort 1966. …”
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2114
Immune and oxidative stress disorder in ovulation-dysfunction women revealed by single-cell transcriptome
Published 2023-12-01“…Although the impact of immune cells in human reproduction has been widely investigated, systematic understanding of the changes of the immune atlas under female ovulation remain less understood.MethodsHere, we generated single cell transcriptomic profiles of 80,689 PBMCs in three representative statuses of ovulation dysfunction, i.e., polycystic ovary syndrome (PCOS), primary ovarian insufficiency (POI) and menopause (MENO), and identified totally 7 major cell types and 25 subsets of cells.ResultsOur study revealed distinct cluster distributions of immune cells among individuals of ovulation disorders and health. …”
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2115
Evaluation of socio-demographic and clinical characteristics of PCOS patients attending a tertiary care institute in Colombo
Published 2022-11-01“…Abstract Background and objectives Polycystic ovary syndrome (PCOS) is a common endocrine disorder with heterogeneous aetiology. …”
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2116
Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis
Published 2024-04-01“…Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5–20% of reproductive-age women. …”
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2117
Familial Diabetes in Obese PCOS Predisposes Individuals to Compensatory Hyperinsulinemia and Insulin Resistance (IR) Also for Reduced Hepatic Insulin Extraction (HIE)
Published 2022-05-01“…<b>Background:</b> Polycystic ovary syndrome (PCOS) is a frequent reproductive disease characterized by hyperandrogenism, oligo /anovulation, and polycystic aspects at ultrasound. …”
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2118
Which Ovarian Reserve Marker is More Reliable in IVF Patients with AMH and AFC Discordance?
Published 2024-02-01“…In the logistic regression analysis, age was not a significant patient factor affecting the ART outcomes; however, the patient’s status of polycystic ovary syndrome (PCOS) was significantly associated with the AMH-AFC discordance, with an odds ratio (OR) of 1.24. …”
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2119
The effects of serum concentration of androgens, LH and IGF1 in early follicular phase on follicular growth parameters and pregnancy rate
Published 2016-03-01“…Patients were excluded if they had polycystic ovary syndrome (PCOS) or endometriosis. The serum concentration of androgens (testosterone, dehydroepiandrosterone and androstenedione), LH and IGF1 was measured on the third day of menstruation. …”
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2120
Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice
Published 2020-01-01“…Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility. …”
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