Gut microbiome in PCOS associates to serum metabolomics: a cross-sectional study by Zheng Yu, Erqi Qin, Shirui Cheng, Han Yang, Rui Liu, Tian Xu, Yanqin Liu, Jing Yuan, Shuguang Yu, Jie Yang, Fanrong Liang

“…Abstract The association between gut microbiome and chronic metabolic disease including polycystic ovary syndrome (PCOS), is well documented, however, the relationship between the gut microbiota and serum metabolites remains unknown. …”
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Risk of Insulin Resistance and Metabolic Syndrome in Women with Hyperandrogenemia: A Comparison between PCOS Phenotypes and Beyond by Valentin Borzan, Elisabeth Lerchbaum, Cornelia Missbrenner, Annemieke C. Heijboer, Michaela Goschnik, Christian Trummer, Verena Theiler-Schwetz, Christoph Haudum, Roswitha Gumpold, Natascha Schweighofer, Barbara Obermayer-Pietsch

“…Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in premenopausal women, with a wide spectrum of possible phenotypes, symptoms and sequelae according to the current clinical definition. …”
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Causal association between lipid-lowering drugs and female reproductive endocrine diseases: a drug-targeted Mendelian randomization study by Jing Zhao, Runfang Wang, Liyun Song, Hua Han, Pei Wang, Yuan Zhao, Yunxia Zhang, Hongzhen Zhang

“…Alongside coronary heart disease as a positive control, our main outcomes of interest included the risk of polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI), premenstrual syndrome (PMS), abnormal uterine bleeding (including menorrhagia and oligomenorrhea), and infertility.ResultsPCSK9 inhibitors significantly increased the risk of infertility in patients (OR [95%CI] = 1.14 [1.06, 1.23], p<0.05). …”
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What minimal detectable effect size is in your power – An inverted sample size formular for survival data by M. K. Dalgaard, A.-E. Christensen, M. K. Kjeldsen

“…Furthermore, we apply this to an ongoing project on data from the Danish national registers, comparing the risk of developing polycystic ovary syndrome (PCOS) associated with treatment with valproic acid in a population with bipolar disorder or epilepsy. …”
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Mammary gland condition in premenopausal women with endometrial hyperplasia by Y. E. Dobrokhotova, M. R. Narimanova, L. V. Saprykina, I. Yu. Ilina, M. L. Mazo

“…Amidst a steady increase in hyperplastic processes in uterus and mammary glands, numerous studies have shown that women with dyshormonal pathology of mammary glands had a range of gynecological diseases: external or internal endometriosis, hyperplastic processes of the endometrium and myometrium, polyps, polycystic ovary syndrome (PCOS), etc.Objective. To assess the mammary gland condition in premenopausal women with endometrial hyperplasia during indole-3-car-binol (I3C) therapy.Materials and methods. …”
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Non-Classical Congenital Adrenal Hyperplasia-Causing Alleles in Adolescent Girls with PCOS and in Risk Group for PCOS Development by Lasma Lidaka, Laine Bekere, Gunta Lazdane, Iveta Dzivite-Krisane, Anda Kivite-Urtane, Linda Gailite

“…Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. …”
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Pioglitazone suppresses excessive follicular development in murine preantral follicles by Sachiko Nagao, Tsuyoshi Baba, Yuya Fujibe, Sayaka Adachi, Keiko Ikeda, Miyuki Morishita, Yoshika Kuno, Hiroyuki Honnma, Toshiaki Endo, Tamotsu Kiya, Tsuyoshi Saito

“…Abstract Polycystic ovary syndrome (PCOS) is an endocrine disease that is common in women in their reproductive period. …”
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Maternal Preconception Glucose Homeostasis and Insulin Resistance Are Associated with Singleton and Twin Birthweight of Neonates Conceived by PCOS Women Undergoing IVF/ICSI Cycles by Huahua Jiang, Yaxin Guo, Lixue Chen, Huifeng Shi, Ning Huang, Hongbin Chi, Rui Yang, Xiaoyu Long, Jie Qiao

“…Polycystic ovary syndrome (PCOS) can induce fertility and metabolism disorders, which may increase the prevalence of glucose metabolism disorders and cause health hazards to women and their offspring. …”
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LASSO and Bioinformatics Analysis in the Identification of Key Genes for Prognostic Genes of Gynecologic Cancer by Shao-Hua Yu, Jia-Hua Cai, De-Lun Chen, Szu-Han Liao, Yi-Zhen Lin, Yu-Ting Chung, Jeffrey J. P. Tsai, Charles C. N. Wang

“…PAMR1 is a tumor suppressor gene, and many studies have proven that overexpression of the gene markedly suppresses cell growth, especially in breast cancer and polycystic ovary syndrome; (2.) SLC24A3 is a sodium–calcium regulator of cells, and high SLC24A3 levels are associated with poor prognosis. …”
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Regulatory Functions of L-Carnitine, Acetyl, and Propionyl L-Carnitine in a PCOS Mouse Model: Focus on Antioxidant/Antiglycative Molecular Pathways in the Ovarian Microenvironment by Giovanna Di Emidio, Francesco Rea, Martina Placidi, Giulia Rossi, Domenica Cocciolone, Ashraf Virmani, Guido Macchiarelli, Maria Grazia Palmerini, Anna Maria D’Alessandro, Paolo Giovanni Artini, Carla Tatone

“…Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with female infertility. …”
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Dietary Intake, Eating Behavior, Physical Activity, and Quality of Life in Infertile Women with PCOS and Obesity Compared with Non-PCOS Obese Controls by Zheng Wang, Henk Groen, Astrid E. P. Cantineau, Tessa M. van Elten, Matty D. A. Karsten, Anne M. van Oers, Ben W. J. Mol, Tessa J. Roseboom, Annemieke Hoek

“…To personalize lifestyle advice for women with polycystic ovary syndrome (PCOS) and obesity, detailed information regarding dietary intake, eating behavior, physical activity levels, and quality of life (QoL) may be useful. …”
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Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice by Bradley B. Jamieson, Aleisha M. Moore, Dayanara B. Lohr, Simone X. Thomas, Lique M. Coolen, Michael N. Lehman, Rebecca E. Campbell, Richard Piet, Richard Piet

“…Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. …”
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Serum uric acid did not affect embryonic and pregnancy outcomes in women without PCOS during IVF procedures by Niwei Yan, Niwei Yan, Niwei Yan, Junli Song, Junli Song, Huiying Jie, Huiying Jie, Pingyin Lee, Pingyin Lee, Simin Liu, Simin Liu, Yuan Yuan, Yuan Yuan

“…A previous study confirmed the association between high serum uric acid levels and poor prognosis of in vitro fertilization (IVF) treatment in polycystic ovary syndrome (PCOS) patients. This study aimed to explore the correlation between serum uric acid levels and reproductive outcomes in patients without PCOS.MethodsA retrospective study that included 1057 patients who underwent pre-implantation genetic testing for monogenic disorders (PGT-M) treatment from January 2013 to December 2020 was conducted. …”
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Familial Occurrence of Adult Granulosa Cell Tumors: Analysis of Whole-Genome Germline Variants by Joline F. Roze, Joachim Kutzera, Wouter Koole, Margreet G. E. M. Ausems, Kristi Engelstad, Jurgen M. J. Piek, Cor D. de Kroon, René H. M. Verheijen, Gijs van Haaften, Ronald P. Zweemer, Glen R. Monroe

“…Furthermore, polycystic ovary syndrome (PCOS) and subfertility was reported in three families. …”
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Adverse Effects of Polycystic Ovarian Syndrome on Pregnancy Outcomes in Women With Frozen-Thawed Embryo Transfer: Propensity Score-Matched Study by Zhexin Ni, Shanshan Mei, Siting You, Yi Lin, Wen Cheng, Ling Zhou, Yanping Kuang, Chaoqin Yu, Chaoqin Yu

“…PurposeThis work aimed to evaluate the adverse effect of polycystic ovary syndrome (PCOS) on pregnancy outcomes of singletons after vitrification in women with frozen-thawed embryo transfer (FET).MethodsPatients with/without PCOS who underwent FET from January 2013 and December 2018 were included. …”
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Selective peripheral tissue response to high testosterone levels in an infertile woman without virilization signs by Viviana Ostrovsky, Mira Ulman, Rina Hemi, Samuel Lurie, Inon Hazan, Alon Ben Ari, Oleg Sukmanov, Tal Schiller, Alena Kirzhner, Taiba Zornitzki

“…Total testosterone, which is peripherally converted to its biologically active form dihydrotestosterone (DHT), is the first-line hormone investigation in hyperandrogenic states and infertility in premenopausal women. Polycystic ovary syndrome (PCOS), the most common cause of hyperandrogenism and infertility in young women, is often associated with mild elevations of total testosterone. …”
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Fatty infiltration of the pancreas: a systematic concept analysis by Mueataz A. Mahyoub, Mueataz A. Mahyoub, Mueataz A. Mahyoub, Mueataz A. Mahyoub, Mohamed Elhoumed, Mohamed Elhoumed, Abdulfatah Hassan Maqul, Abdulfatah Hassan Maqul, Maged Almezgagi, Maged Almezgagi, Maged Almezgagi, Mustafa Abbas, Yang Jiao, Jinhai Wang, Mohammed Alnaggar, Mohammed Alnaggar, Ping Zhao, Shuixiang He, Shuixiang He

“…This review article highlights the various disorders for which FIP has been established as a risk factor, including type 2 diabetes mellitus (T2DM), pancreatitis, pancreatic fistula (PF), metabolic syndrome (MS), polycystic ovary syndrome (PCOS), and pancreatic duct adenocarcinoma (PDAC), as well as the new investigation tools. …”
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Liraglutide as an innovative and multifunctional drug for patients with obesity – the current state of knowledge and future prospects by Maria Grodkiewicz, Paweł Kozieł, Klaudia Artykiewicz, Kamila Gorczyca, Marcin Czarkowski, Aleksandra Słupczyńska, Weronika Urbaś, Klaudia Podgórska, Aleksandra Puła, Urszula Krzysiek

“…For this reason, in the latest recommendations of the Polish Obesity Treatment Association, liraglutide is indicated as the drug of first choice for obese or overweight patients with a BMI ≥27 kg / m2, in whom coexisting: pre-diabetes, type 2 diabetes, arterial hypertension, polycystic ovary syndrome, nonalcoholic fatty liver disease, metabolic syndrome, atherosclerosis or sleep apnea syndrome. …”
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Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450 by Katyayani Sharma, Angelo Lanzilotto, Jibira Yakubu, Søren Therkelsen, Clarissa Daniela Vöegel, Therina Du Toit, Flemming Steen Jørgensen, Amit V. Pandey

“…High levels of circulating androgens are linked to PCa in men and Polycystic Ovary Syndrome (PCOS) in women. Essential oils or their metabolites, like lavender oil and tea tree oil, have been reported to act as potential EDCs and contribute towards sex steroid imbalance in cases of prepubertal gynecomastia in boys and premature thelarche in girls due to the exposure to lavender-based fragrances. …”
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Gynecological Cancers and Microbiota Dynamics: Insights into Pathogenesis and Therapy by Giovanna Cocomazzi, Lino Del Pup, Viviana Contu, Gabriele Maggio, Lodovico Parmegiani, Walter Ciampaglia, Daniele De Ruvo, Raffaele Faioli, Annamaria Maglione, Giorgio Maria Baldini, Domenico Baldini, Valerio Pazienza

“…Female genital tract dysbiosis and its possible impact on pathologies such as endometriosis, polycystic ovary syndrome (PCOS), pelvic inflammatory disease (PID), and gynecological cancers have been unveiled. …”
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