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2121
Gut microbiome in PCOS associates to serum metabolomics: a cross-sectional study
Published 2022-12-01“…Abstract The association between gut microbiome and chronic metabolic disease including polycystic ovary syndrome (PCOS), is well documented, however, the relationship between the gut microbiota and serum metabolites remains unknown. …”
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2122
Risk of Insulin Resistance and Metabolic Syndrome in Women with Hyperandrogenemia: A Comparison between PCOS Phenotypes and Beyond
Published 2021-02-01“…Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in premenopausal women, with a wide spectrum of possible phenotypes, symptoms and sequelae according to the current clinical definition. …”
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2123
Causal association between lipid-lowering drugs and female reproductive endocrine diseases: a drug-targeted Mendelian randomization study
Published 2023-11-01“…Alongside coronary heart disease as a positive control, our main outcomes of interest included the risk of polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI), premenstrual syndrome (PMS), abnormal uterine bleeding (including menorrhagia and oligomenorrhea), and infertility.ResultsPCSK9 inhibitors significantly increased the risk of infertility in patients (OR [95%CI] = 1.14 [1.06, 1.23], p<0.05). …”
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2124
What minimal detectable effect size is in your power – An inverted sample size formular for survival data
Published 2023-03-01“…Furthermore, we apply this to an ongoing project on data from the Danish national registers, comparing the risk of developing polycystic ovary syndrome (PCOS) associated with treatment with valproic acid in a population with bipolar disorder or epilepsy. …”
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2125
Mammary gland condition in premenopausal women with endometrial hyperplasia
Published 2021-04-01“…Amidst a steady increase in hyperplastic processes in uterus and mammary glands, numerous studies have shown that women with dyshormonal pathology of mammary glands had a range of gynecological diseases: external or internal endometriosis, hyperplastic processes of the endometrium and myometrium, polyps, polycystic ovary syndrome (PCOS), etc.Objective. To assess the mammary gland condition in premenopausal women with endometrial hyperplasia during indole-3-car-binol (I3C) therapy.Materials and methods. …”
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2126
Non-Classical Congenital Adrenal Hyperplasia-Causing Alleles in Adolescent Girls with PCOS and in Risk Group for PCOS Development
Published 2021-05-01“…Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women. …”
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2127
Pioglitazone suppresses excessive follicular development in murine preantral follicles
Published 2019-08-01“…Abstract Polycystic ovary syndrome (PCOS) is an endocrine disease that is common in women in their reproductive period. …”
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2128
Maternal Preconception Glucose Homeostasis and Insulin Resistance Are Associated with Singleton and Twin Birthweight of Neonates Conceived by PCOS Women Undergoing IVF/ICSI Cycles
Published 2023-06-01“…Polycystic ovary syndrome (PCOS) can induce fertility and metabolism disorders, which may increase the prevalence of glucose metabolism disorders and cause health hazards to women and their offspring. …”
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2129
LASSO and Bioinformatics Analysis in the Identification of Key Genes for Prognostic Genes of Gynecologic Cancer
Published 2021-11-01“…PAMR1 is a tumor suppressor gene, and many studies have proven that overexpression of the gene markedly suppresses cell growth, especially in breast cancer and polycystic ovary syndrome; (2.) SLC24A3 is a sodium–calcium regulator of cells, and high SLC24A3 levels are associated with poor prognosis. …”
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2130
Regulatory Functions of L-Carnitine, Acetyl, and Propionyl L-Carnitine in a PCOS Mouse Model: Focus on Antioxidant/Antiglycative Molecular Pathways in the Ovarian Microenvironment
Published 2020-09-01“…Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with female infertility. …”
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2131
Dietary Intake, Eating Behavior, Physical Activity, and Quality of Life in Infertile Women with PCOS and Obesity Compared with Non-PCOS Obese Controls
Published 2021-10-01“…To personalize lifestyle advice for women with polycystic ovary syndrome (PCOS) and obesity, detailed information regarding dietary intake, eating behavior, physical activity levels, and quality of life (QoL) may be useful. …”
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2132
Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice
Published 2022-08-01“…Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. …”
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2133
Serum uric acid did not affect embryonic and pregnancy outcomes in women without PCOS during IVF procedures
Published 2024-02-01“…A previous study confirmed the association between high serum uric acid levels and poor prognosis of in vitro fertilization (IVF) treatment in polycystic ovary syndrome (PCOS) patients. This study aimed to explore the correlation between serum uric acid levels and reproductive outcomes in patients without PCOS.MethodsA retrospective study that included 1057 patients who underwent pre-implantation genetic testing for monogenic disorders (PGT-M) treatment from January 2013 to December 2020 was conducted. …”
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2134
Familial Occurrence of Adult Granulosa Cell Tumors: Analysis of Whole-Genome Germline Variants
Published 2021-05-01“…Furthermore, polycystic ovary syndrome (PCOS) and subfertility was reported in three families. …”
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2135
Adverse Effects of Polycystic Ovarian Syndrome on Pregnancy Outcomes in Women With Frozen-Thawed Embryo Transfer: Propensity Score-Matched Study
Published 2022-06-01“…PurposeThis work aimed to evaluate the adverse effect of polycystic ovary syndrome (PCOS) on pregnancy outcomes of singletons after vitrification in women with frozen-thawed embryo transfer (FET).MethodsPatients with/without PCOS who underwent FET from January 2013 and December 2018 were included. …”
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2136
Selective peripheral tissue response to high testosterone levels in an infertile woman without virilization signs
Published 2024-04-01“…Total testosterone, which is peripherally converted to its biologically active form dihydrotestosterone (DHT), is the first-line hormone investigation in hyperandrogenic states and infertility in premenopausal women. Polycystic ovary syndrome (PCOS), the most common cause of hyperandrogenism and infertility in young women, is often associated with mild elevations of total testosterone. …”
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2137
Fatty infiltration of the pancreas: a systematic concept analysis
Published 2023-09-01“…This review article highlights the various disorders for which FIP has been established as a risk factor, including type 2 diabetes mellitus (T2DM), pancreatitis, pancreatic fistula (PF), metabolic syndrome (MS), polycystic ovary syndrome (PCOS), and pancreatic duct adenocarcinoma (PDAC), as well as the new investigation tools. …”
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2138
Liraglutide as an innovative and multifunctional drug for patients with obesity – the current state of knowledge and future prospects
Published 2022-11-01“…For this reason, in the latest recommendations of the Polish Obesity Treatment Association, liraglutide is indicated as the drug of first choice for obese or overweight patients with a BMI ≥27 kg / m2, in whom coexisting: pre-diabetes, type 2 diabetes, arterial hypertension, polycystic ovary syndrome, nonalcoholic fatty liver disease, metabolic syndrome, atherosclerosis or sleep apnea syndrome. …”
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2139
Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450
Published 2024-02-01“…High levels of circulating androgens are linked to PCa in men and Polycystic Ovary Syndrome (PCOS) in women. Essential oils or their metabolites, like lavender oil and tea tree oil, have been reported to act as potential EDCs and contribute towards sex steroid imbalance in cases of prepubertal gynecomastia in boys and premature thelarche in girls due to the exposure to lavender-based fragrances. …”
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2140
Gynecological Cancers and Microbiota Dynamics: Insights into Pathogenesis and Therapy
Published 2024-02-01“…Female genital tract dysbiosis and its possible impact on pathologies such as endometriosis, polycystic ovary syndrome (PCOS), pelvic inflammatory disease (PID), and gynecological cancers have been unveiled. …”
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