Effects of maternal characteristics and medical history on first trimester biomarkers for preeclampsia by Johnatan Torres-Torres, Johnatan Torres-Torres, Salvador Espino-y-Sosa, Salvador Espino-y-Sosa, Jose Rafael Villafan-Bernal, Jose Rafael Villafan-Bernal, Luis Enrique Orozco-Guzman, Juan Mario Solis-Paredes, Guadalupe Estrada-Gutierrez, Romeo Adalid Martinez-Cisneros, Paloma Mateu-Rogell, Paloma Mateu-Rogell, Sandra Acevedo-Gallegos, Raigam Jafet Martinez-Portilla, Raigam Jafet Martinez-Portilla

“…Characteristics that significantly influenced PLGF were fetal crown rump length (CRL), maternal age, nulliparity, body mass index (BMI), chronic hypertension, Lupus, spontaneous pregnancy, polycystic ovary syndrome (PCOS), hypothyroidism, preeclampsia (PE) in a previous pregnancy, and mother with PE. …”
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Effect of quercetin on steroidogenesis and folliculogenesis in ovary of mice with experimentally-induced polycystic ovarian syndrome by Mohd Zahoor ul haq Shah, Vinoy kumar Shrivastva, Manzoor Ahmad Mir, Wajid Mohammad Sheikh, Mohd Ashraf Ganie, Gulzar Ahmed Rather, Majid Shafi, Showkeen Muzamil Bashir, Mohammad Azam Ansari, Meneerah A. Al-Jafary, Mohammad H. Al-Qahtani, Abdalelgadir Musa Homeida, Ebtesam A. Al-Suhaimi

“…IntroductionPolycystic Ovary syndrome (PCOS) affects the health of many women around the world. …”
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Bilirubin Concentration in Follicular Fluid Is Increased in Infertile Females, Correlates with Decreased Antioxidant Levels and Increased Nitric Oxide Metabolites, and Negatively A... by Renata Mangione, Romina Pallisco, Gabriele Bilotta, Francesca Marroni, Valentina Di Pietro, Elena Capoccia, Giuseppe Lazzarino, Barbara Tavazzi, Giacomo Lazzarino, Pasquale Bilotta, Angela Maria Amorini

“…Using the same FF samples of this previous study, we here analyzed the FF concentrations of free and bound bilirubin and compared the results obtained in CFF, IF and the different subgroups of IF (endometriosis, EM, polycystic ovary syndrome, PCOS, age-related reduced ovarian reserve, AR-ROR, reduced ovarian reserve, ROR, genetic infertility, GI and unexplained infertility, UI). …”
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Transcriptome analysis identification of A-to-I RNA editing in granulosa cells associated with PCOS by Fan-Sheng Kong, Fan-Sheng Kong, Zijing Lu, Zijing Lu, Yuan Zhou, Yuan Zhou, Yinghua Lu, Chun-Yan Ren, Ruofan Jia, Ruofan Jia, Beilei Zeng, Beilei Zeng, Panwang Huang, Panwang Huang, Jihong Wang, Yaping Ma, Yaping Ma, Jian-Huan Chen, Jian-Huan Chen, Jian-Huan Chen

“…BackgroundPolycystic ovary syndrome (PCOS) is a complex, multifactor disorder in women of reproductive age worldwide. …”
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Metabolic Cytokines at Fasting and During Macronutrient Challenges: Influence of Obesity, Female Androgen Excess and Sex by M. Ángeles Martínez-García, Samuel Moncayo, María Insenser, Francisco Álvarez-Blasco, Manuel Luque-Ramírez, Héctor F. Escobar-Morreale

“…Methods: On alternate days we submitted 17 women with polycystic ovary syndrome (PCOS) (9 non-obese, 8 obese), 17 non-hyperandrogenic control women (9 non-obese, 8 obese) and 19 control men (10 non-obese, 9 obese) to isocaloric oral glucose, lipid and protein loads. …”
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Hiperplasia adrenal congênita: dosagem da 17-hidroxiprogesterona basal para seleção e casos para realização do teste de estímulo com ACTH sintético Congenital adrenal hyperplasia:... by Lúcia Helena Coelho Nóbrega, Josivan Gomes de Lima, Maria Lúcia Coelho Nóbrega, Ana Luiza de Souza Brito, Raphael Pinto de Mendonça

“…Clinical presentation varies from life-threatening salt-losing adrenal hyperplasia to simple androgenic states, which can be of late-onset and very similar to polycystic ovary syndrome. Diagnosis is usually made by synthetic ACTH provocative tests but efforts are being made to simplify this investigation. …”
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Diversity of the Gut Microbiota in Dihydrotestosterone-Induced PCOS Rats and the Pharmacologic Effects of Diane-35, Probiotics, and Berberine by Feifei Zhang, Feifei Zhang, Feifei Zhang, Tong Ma, Peng Cui, Amin Tamadon, Shan He, Chuanbing Huo, Gulinazi Yierfulati, Xiaoqing Xu, Wei Hu, Xin Li, Xin Li, Linus R. Shao, Hongwei Guo, Yi Feng, Congjian Xu, Congjian Xu

“…Polycystic ovary syndrome (PCOS) is a frequent endocrine and metabolic syndrome in reproductive-age women. …”
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Higher risk of pre-eclampsia and other vascular disorders with artificial cycle for frozen-thawed embryo transfer compared to ovulatory cycle or to fresh embryo transfer following... by Sylvie Epelboin, Julie Labrosse, Jacques De Mouzon, Aviva Devaux, Marie-José Gervoise-Boyer, Laetitia Hesters, Philippe Jonveaux, Rachel Levy, Nathalie Sermondade, Patricia Fauque, Fabienne Pessione

“…Results were adjusted for maternal characteristics and infertility (age, parity, smoking, obesity, history of diabetes or hypertension, endometriosis, polycystic ovary syndrome and premature ovarian insufficiency).ResultsA total of 68025 single deliveries were included: fresh-ET (n=48152), OC-FET (n=9500), AC-FET (n=10373). …”
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Genotype, Mortality, Morbidity, and Outcomes of 3β-Hydroxysteroid Dehydrogenase Deficiency in Algeria by Asmahane Ladjouze, Malcolm Donaldson, Ingrid Plotton, Nacima Djenane, Kahina Mohammedi, Véronique Tardy-Guidollet, Delphine Mallet, Kamélia Boulesnane, Zair Bouzerar, Yves Morel, Florence Roucher-Boulez

“…Four girls reached menarche at 14.3 (11–14.5) years, with three developing adrenal masses (surgically excised in two) and polycystic ovary syndrome (PCOS), with radiological evidence of ovarian adrenal rest tumor in one. …”
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Establishing Normative Values to Determine the Prevalence of Biochemical Hyperandrogenism in Premenopausal Women of Different Ethnicities from Eastern Siberia by Larisa Suturina, Daria Lizneva, Alina Atalyan, Ludmila Lazareva, Aleksey Belskikh, Tatyana Bairova, Leonid Sholokhov, Maria Rashidova, Irina Danusevich, Iana Nadeliaeva, Lilia Belenkaya, Zorikto Darzhaev, Eldar Sharifulin, Natalia Belkova, Ilia Igumnov, Tatyana Trofimova, Anastasiya Khomyakova, Kseniia Ievleva, Natalia Babaeva, Irina Egorova, Madinabonu Salimova, Bulent O. Yildiz, Richard S. Legro, Frank Z. Stanczyk, Ricardo Azziz

“…Androgen assessment is a key element for diagnosing polycystic ovary syndrome (PCOS), and defining a “normal” level of circulating androgens is critical for epidemiological studies. …”
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Homeostatic Model Assessment for Insulin Resistance Is Associated With Late Miscarriage in Non-Dyslipidemic Women Undergoing Fresh IVF/ICSI Embryo Transfer by Tianli Yang, Tianli Yang, Yuanyuan Yang, Yuanyuan Yang, Qiong Zhang, Qiong Zhang, Donge Liu, Donge Liu, Nenghui Liu, Nenghui Liu, Yumei Li, Yumei Li, Zhongyuan Yao, Zhongyuan Yao, Yeqing Zhang, Yeqing Zhang, Fen Tian, Fen Tian, Jing Zhao, Jing Zhao, Yanping Li, Yanping Li

“…Subgroup analysis based on presence or absence of the polycystic ovary syndrome (PCOS) status was also performed to analyze the effects of HOMA-IR among non-PCOS populations.ResultsThe late miscarriage rate and percentage of macrosomia increased with the HOMA-IR group (for late miscarriage rate: 2.23% vs. 3.04% vs. 7.35%, P<0.001; for macrosomia: 0.21% vs. 1.70% vs. 3.23%, P=0.002). …”
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Risk of endometrial cancer in women treated with ovary-stimulating drugs for subfertility by Skalkidou, A, Sergentanis, T, Gialamas, S, Georgakis, M, Psaltopoulou, T, Trivella, M, Siristatidis, C, Evangelou, E, Petridou, E

“…This may largely be due to underlying risk factors in women who need treatment with clomiphene citrate, such as polycystic ovary syndrome, rather than exposure to the drug itself. …”

Exploration of molecular features of PCOS with different androgen levels and immune-related prognostic biomarkers associated with implantation failure by Qinyu Gao, Qinyu Gao, Qinyu Gao, Cong Ma, Cong Ma, Cong Ma, Shuyu Meng, Guanxiong Wang, Guanxiong Wang, Guanxiong Wang, Qiong Xing, Qiong Xing, Qiong Xing, Yuping Xu, Yuping Xu, Yuping Xu, Xiaojin He, Xiaojin He, Xiaojin He, Tianjuan Wang, Tianjuan Wang, Tianjuan Wang, Yunxia Cao, Yunxia Cao, Yunxia Cao

“…BackgroundPolycystic ovary syndrome (PCOS), the most common heterogeneous reproductive disease afflicting women of childbearing age, has been recognized as a chronic inflammatory disease recently. …”
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AMH concentrations in infancy and mid-childhood predict ovarian activity in adolescence: A long-term longitudinal study of healthy girlsResearch in context by Casper P. Hagen, Margit Bistrup Fischer, Christine Wohlfahrt-Veje, Maria Assens, Alexander S. Busch, Anette Tønnes Pedersen, Anders Juul, Katharina M. Main

“…In contrast, patients with polycystic ovary syndrome (PCOS) have elevated AMH. The primary aim of this study was to evaluate the individual tracking of serum AMH concentrations, as well as whether AMH in early childhood reflects ovarian activity in adolescence. …”
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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation by Susan Martin, Jessica Tyrrell, E Louise Thomas, Matthew J Bown, Andrew R Wood, Robin N Beaumont, Lam C Tsoi, Philip E Stuart, James T Elder, Philip Law, Richard Houlston, Christopher Kabrhel, Nikos Papadimitriou, Marc J Gunter, Caroline J Bull, Joshua A Bell, Emma E Vincent, Naveed Sattar, Malcolm G Dunlop, Ian PM Tomlinson, Sara Lindström, INVENT consortium, Jimmy D Bell, Timothy M Frayling, Hanieh Yaghootkar

“…Here, MR with the FA and UFA genetics showed opposing effects on risk of disease: coronary artery disease, peripheral artery disease, hypertension, stroke, type 2 diabetes, polycystic ovary syndrome, heart failure, atrial fibrillation, chronic kidney disease, renal cancer, and gout. …”
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Inflammation mediates the effect of adiposity and lipid metabolism indicators on the embryogenesis of PCOS women undergoing in vitro fertilization/intracytoplasmic sperm injection by Huahua Jiang, Huahua Jiang, Huahua Jiang, Huahua Jiang, Lixue Chen, Lixue Chen, Lixue Chen, Lixue Chen, Tian Tian, Tian Tian, Tian Tian, Tian Tian, Huifeng Shi, Huifeng Shi, Huifeng Shi, Ning Huang, Ning Huang, Ning Huang, Ning Huang, Hongbin Chi, Hongbin Chi, Hongbin Chi, Hongbin Chi, Rui Yang, Rui Yang, Rui Yang, Rui Yang, Xiaoyu Long, Xiaoyu Long, Xiaoyu Long, Xiaoyu Long, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao

“…BackgroundPolycystic ovary syndrome (PCOS) is a complex reproductive endocrine and metabolic disease affecting women of reproductive age. …”
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Inositols: From Established Knowledge to Novel Approaches by Simona Dinicola, Vittorio Unfer, Fabio Facchinetti, Christophe O. Soulage, Nicholas D. Greene, Mariano Bizzarri, Antonio Simone Laganà, Shiao-Yng Chan, Arturo Bevilacqua, Lali Pkhaladze, Salvatore Benvenga, Annarita Stringaro, Daniele Barbaro, Marialuisa Appetecchia, Cesare Aragona, Maria Salomè Bezerra Espinola, Tonino Cantelmi, Pietro Cavalli, Tony T. Chiu, Andrew J. Copp, Rosario D’Anna, Didier Dewailly, Cherubino Di Lorenzo, Evanthia Diamanti-Kandarakis, Imelda Hernández Marín, Moshe Hod, Zdravko Kamenov, Eleni Kandaraki, Giovanni Monastra, Mario Montanino Oliva, John E. Nestler, Maurizio Nordio, Ali C. Ozay, Olga Papalou, Giuseppina Porcaro, Nikos Prapas, Scott Roseff, Monica Vazquez-Levin, Ivana Vucenik, Artur Wdowiak

“…Currently both myo-Ins and D-chiro-Ins are well-tolerated, effective alternative candidates to the classical insulin sensitizers, and are useful treatments in preventing and treating metabolic and reproductive disorders such as polycystic ovary syndrome (PCOS), gestational diabetes mellitus (GDM), and male fertility disturbances, like sperm abnormalities. …”
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Effect of Nutritional Supplementation on Oxidative Stress and Hormonal and Lipid Profiles in PCOS-Affected Females by Pallavi Dubey, Sireesha Reddy, Sarah Boyd, Christina Bracamontes, Sheralyn Sanchez, Munmun Chattopadhyay, Alok Dwivedi

“…Polycystic ovary syndrome (PCOS) affects several reproductive and endocrine features in females and has a poorly understood etiology. …”
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Clinical Approaches to Nestorone Subdermal Implant Therapy in Women’s Health by Guilherme Renke, Consuelo Callizo, Raphaela Paes, Mariana Antunes, Glaycon Michels, Luana Concha, Ordânio Almeida, Christiane Valente, Thomaz Baesso, Bruna Giovannoni

“…In recent years, its potential uses in endometriosis, polycystic ovaries syndrome (PCOS), and a new therapeutic possibility for neuroprotection have made this treatment extremely interesting. …”
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Implantation and Decidualization in PCOS: Unraveling the Complexities of Pregnancy by Satoko Matsuyama, Sarah Whiteside, Shu-Yun Li

“…Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age, affecting 5–15% globally with a large proportion undiagnosed. …”
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