Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial by Ali Jadidi, Alireza Rezaei Ashtiani, Ali Khanmohamadi Hezaveh, Seyed Mohamad Aghaepour

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July 2023 Sleep Case of the Month: Fighting for a Good Night’s Sleep by Meneena Bright MD

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Dopaminergic agonists in Parkinson's disease by A. Alonso Cánovas, R. Luquin Piudo, P. García Ruiz-Espiga, J.A. Burguera, V. Campos Arillo, A. Castro, G. Linazasoro, J. López Del Val, L. Vela, J.C. Martínez Castrillo

“…Suspending any DA, especially pramipexole, has been linked to onset of apathy, which may be severe. …”
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Burning mouth syndrome: clinical description, pathophysiological approach, and a new therapeutic option by A. Cárcamo Fonfría, L. Gómez-Vicente, M.I. Pedraza, M.L. Cuadrado-Pérez, A.L. Guerrero Peral, J. Porta-Etessam

“…Each patient had previously received conventional treatments without amelioration. Pramipexol was initiated in doses between 0.36 mg and 1.05 mg per day, resulting in clear improvement of symptoms in all cases, a situation which continues after a 4-year follow up period. …”
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Parkinsonismo inducido por telmisartán: Reporte de caso by Luis José Fernández Yépez, Luis Alfredo Blanco Castiblanco, Elias José Fernández Fernández, Erwin Javier Fernandez Fernández

“…PRESENTACIÓN DE CASO: Hombre de 78 años, con antecedentes de enfermedad de Parkinson de dos años de evolución, controlada con levodopa, pramipexol ER y amantadina, ingresa al servicio de urgencias por empeoramiento del parkinsonismo en las dos semanas previas a la consulta. …”
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Alterações laboratoriais dos medicamentos atuantes no sistema nervoso de uma Relação Municipal de Medicamentos Essenciais do nordeste brasileiro by Laércio Silva GOMES, Bárbara Rebeca PEREIRA, Lucas Mendes DIAS, Juliene Lima MESQUITA, Bruna Victória PASSOS, Mônica Helena SOUSA

“…Biperideno, clobazam, hidroxizina, nicotina, pramipexol, piridostigmina, rivastigmina e rasagilina não apresentaram nenhuma alteração in vitro ou in vivo, de acordo com a literatura consultada. …”
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Alterações laboratoriais dos medicamentos atuantes no sistema nervoso de uma Relação Municipal de Medicamentos Essenciais do nordeste brasileiro by Laércio Silva GOMES, Bárbara Rebeca PEREIRA, Lucas Mendes DIAS, Juliene Lima MESQUITA, Bruna Victória PASSOS, Mônica Helena SOUSA

“…Biperideno, clobazam, hidroxizina, nicotina, pramipexol, piridostigmina, rivastigmina e rasagilina não apresentaram nenhuma alteração in vitro ou in vivo, de acordo com a literatura consultada. …”
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Pharmacological Interaction of Quercetin Derivatives of <i>Tilia americana</i> and Clinical Drugs in Experimental Fibromyalgia by Yara Elena Quinto-Ortiz, María Eva González-Trujano, Edith Sánchez-Jaramillo, Gabriel Fernando Moreno-Pérez, Salomón Jacinto-Gutiérrez, Francisco Pellicer, Alonso Fernández-Guasti, Alberto Hernandez-Leon

“…To investigate a possible therapeutic alternative for FM-type pain, an aqueous <i>Tilia</i> extract (TE) and its flavonoid fraction (FF) containing rutin and isoquercitrin were evaluated alone and/or combined with clinical drugs (tramadol—TRA and pramipexol—PRA) using the reserpine-induced FM model in rats. …”
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An experimental medicine investigation of the effects of potential novel antidepressant interventions on emotion and reward related information processing by Kaltenboeck, A

“…The observed effects of the mental practice and of subacute pramipexole treatment deserve further attention and should be interrogated in closer detail in future research.…”

Effects of Anti-Parkinsonian Drugs on Verbal Fluency in Patients with Parkinson’s Disease: A Network Meta-Analysis by Yuxia Zhu, Sichen Li, Hongyu Lai, Lijuan Mo, Changhong Tan, Xi Liu, Fen Deng, Lifen Chen

“…In terms of letter fluency, the ranking of the overall efficacy of included drug regimens was: levodopa, levodopa combined with pramipexole, rotigotine, cabergoline, pramipexole, pergolide, but no drug regimen presented a significant advantage over the others. …”
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Comparison of the Efficacy of Different Drugs on Non-Motor Symptoms of Parkinson’s Disease: a Network Meta-Analysis by Bao-Dong Li, Jing-Jun Cui, Jia Song, Ce Qi, Pei-Feng Ma, Ya-Rong Wang, Jing Bai

“…Background/Aims: A network meta-analysis is used to compare the efficacy of ropinirole, rasagiline, rotigotine, entacapone, apomorphine, pramipexole, sumanirole, bromocriptine, piribedil and levodopa, with placebo as a control, for non-motor symptoms in Parkinson’s disease (PD). …”
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Current therapy for Parkinson's disease by A. V. Obukhova

“…A novel extended-release formulation of pramipexole is considered separately. Both immediate- and extended-release pramipexole formulations contain the same active ingredient and have the same dopamine-receptor interaction profile, but differ in the tablet release rate of the active ingredient. …”
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Psychosis and concurrent impulse control disorder in Parkinson's disease: A review based on a case report by Bruno Fukelmann Guedes, Marcia Rubia Gonçalves, Rubens Gisbert Cury

“…Concurrent psychosis, punding and pathological gambling developed more than six years after the introduction of pramipexole and ceased shortly after the addition of quetiapine and discontinuation of pramipexole. …”
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Comparative efficacy and safety of six non-ergot dopamine-receptor agonists in early Parkinson's disease: a systematic review and network meta-analysis by Xiang-Ting Chen, Qian Zhang, Fei-Fei Chen, Si-Yuan Wen, Chang-Qing Zhou

“…Novel long-acting formulations of NEDAs including pramipexole extended-release (ER), ropinirole prolonged-release (PR), and rotigotine transdermal patch have been developed. …”
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Linking reward-learning and affect in health and depression by Halahakoon, DC

“…Combined with the behavioural modelling, this finding indicates that Pramipexole enhances choice accuracy by reducing the decay of estimated values during reward learning.…”

DO WE RECOGNIZE RESTLESS GENITAL SYNDROME AND DO WE KNOW HOW TO TREAT IT? by T. Radeva

“…In the literature, there are individual cases of patients with the syndrome, who have been administrated treatment with pramipexole. The patient in the present case report has also undergone treatment with pramipexole and has been observed for a period of two years.…”
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Comparative efficacy and safety of adjunctive drugs to levodopa for fluctuating Parkinson’s disease - network meta-analysis by Wataru Sako, Yuki Kogo, Michinori Koebis, Yoshiaki Kita, Hajime Yamakage, Takayuki Ishida, Nobutaka Hattori

“…In terms of tolerability, ropinirole (0.954) ranked the highest, followed by pramipexole (0.857), safinamide (0.717), and ropinirole ER (0.708). …”
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The treatment efficacy of pharmacotherapies for rapid eye movement sleep behavior disorder with polysomnography evaluation: A systematic review and meta-analysis by Zhiqiang Que, Cuifeng Zheng, Zhenhua Zhao, Yanhong Weng, Zhibao Zhu, Yuqi Zeng, Qinyong Ye, Fabin Lin, Guoen Cai

“…We also found that pramipexole had different effects on idiopathic RBD (iRBD) and secondary RBD (sRBD). …”
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Impulse control and related behavioral disorders (ICRD) in Idiopathic Parkinson’s Disease treated with different dopamine agonists in Hong Kong: Is any dopamine agonist better? by Hiu Fung Wu, Ellen Lok Man Yu, Bun Sheng, Kwok Kui Wong, Man Au Yeung, Wa Tai Wong, Hon Hang Kwan, Lun Pei Ng, Chun Hin Cheung, Yan Lok Lam, Yat Kwan Chan

“…Conclusion: Bromocriptine and probably rotigotine carried a lower ICRD risk compared to pramipexole and ropinirole.…”
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Profile and frequency of antiparkinsonian drugs adverse reactions: a systematic review and meta-analysis by A. A. Tappakhov, T. E. Popova, A. I. Vasilev, T. G. Govorova, Yu. I. Khabarova, K. A. Timofeeva, N. A. Schnaider

“…Dizziness was more common with pramipexole and ropinirole than with levodopa (OR=1.82; 95% CI: 1.21–2.74 and OR=1.65; 95% CI: 1.11–2.44 respectively). …”
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